Bus Iquique to Santiago, RM - Compare all Companies

Compare all timetables for the bus from Iquique to Santiago, RM

Here is a selection of the cheapest bus trips from the schedule from Iquique to Santiago, RM from various bus operators like Pullman San Andres, Pluss Chile or Pullman Bus for the next days.

today

$38

tomorrow

$38

Tuesday

$38

Wednesday

$38

Thursday

$38

Friday

$38

Saturday

$42

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Cormar Bus	25h 20m	7:00 AM	Iquique	Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Bus Station, Iquique (Chile) at 3/22/2026 7:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/23/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 25h 20m
Pluss Chile	25h 0m	11:00 AM	Iquique	Bus Station	12:00 PM	Santiago, RM	Sur Bus Station	Premium Economy	$42	A Bus from Pluss Chile goes from Bus Station, Iquique (Chile) at 3/22/2026 11:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/23/2026 12:00:00 PM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 25h 0m
Cikbus Elité	25h 10m	3:20 PM	Iquique	Bus Station	4:30 PM	Santiago, RM	Sur Bus Station	Premium Economy	$44	A Bus from Cikbus Elité goes from Bus Station, Iquique (Chile) at 3/22/2026 3:20:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/23/2026 4:30:00 PM. 50 Premium Economy ticket for $44 per person are available. Travel duration is 25h 10m
Pullman San Andres	26h 0m	9:00 AM	Iquique	Bus Station	11:00 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Pullman San Andres goes from Bus Station, Iquique (Chile) at 3/22/2026 9:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/23/2026 11:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 26h 0m
Ramos Cholele	24h 0m	8:30 AM	Iquique	Bus Station	8:30 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Ramos Cholele goes from Bus Station, Iquique (Chile) at 3/22/2026 8:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/23/2026 8:30:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 24h 0m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Cormar Bus	25h 20m	7:00 AM	Iquique	Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Bus Station, Iquique (Chile) at 3/23/2026 7:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/24/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 25h 20m
Pluss Chile	25h 50m	3:00 AM	Iquique	Bus Station	4:50 AM	Santiago, RM	Sur Bus Station	Premium Economy	$42	A Bus from Pluss Chile goes from Bus Station, Iquique (Chile) at 3/23/2026 3:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/24/2026 4:50:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 25h 50m
Ramos Cholele	24h 0m	8:30 AM	Iquique	Bus Station	8:30 AM	Santiago, RM	Terminal San Borja	Premium Economy	$43	A Bus from Ramos Cholele goes from Bus Station, Iquique (Chile) at 3/23/2026 8:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/24/2026 8:30:00 AM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 24h 0m
Nueva Andimar Vip	24h 20m	7:15 PM	Iquique	Bus Station	7:35 PM	Santiago, RM	Terminal San Borja	Economy	$43	A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/23/2026 7:15:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/24/2026 7:35:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 24h 20m
Cikbus Elité	27h 45m	1:45 AM	Iquique	Bus Station	5:30 AM	Santiago, RM	Sur Bus Station	Premium Economy	$44	A Bus from Cikbus Elité goes from Bus Station, Iquique (Chile) at 3/23/2026 1:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/24/2026 5:30:00 AM. 50 Premium Economy ticket for $44 per person are available. Travel duration is 27h 45m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Cormar Bus	25h 20m	7:00 AM	Iquique	Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Bus Station, Iquique (Chile) at 3/24/2026 7:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/25/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 25h 20m
Pluss Chile	25h 50m	3:00 AM	Iquique	Bus Station	4:50 AM	Santiago, RM	Sur Bus Station	Premium Economy	$42	A Bus from Pluss Chile goes from Bus Station, Iquique (Chile) at 3/24/2026 3:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/25/2026 4:50:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 25h 50m
FlixBus	24h 20m	7:15 PM	Iquique	Bus Station	7:35 PM	Santiago, RM	Terminal San Borja	Economy	$44	A Bus from FlixBus goes from Bus Station, Iquique (Chile) at 3/24/2026 7:15:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/25/2026 7:35:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 24h 20m
Pullman San Andres	26h 0m	9:00 AM	Iquique	Bus Station	11:00 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Pullman San Andres goes from Bus Station, Iquique (Chile) at 3/24/2026 9:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/25/2026 11:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 26h 0m
Ramos Cholele	24h 0m	8:30 AM	Iquique	Bus Station	8:30 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Ramos Cholele goes from Bus Station, Iquique (Chile) at 3/24/2026 8:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/25/2026 8:30:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 24h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Cormar Bus	25h 20m	7:00 AM	Iquique	Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Bus Station, Iquique (Chile) at 3/25/2026 7:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/26/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 25h 20m
Nueva Andimar Vip	24h 20m	7:15 PM	Iquique	Bus Station	7:35 PM	Santiago, RM	Terminal San Borja	Economy	$40	A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/25/2026 7:15:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/26/2026 7:35:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 24h 20m
Pluss Chile	25h 50m	3:00 AM	Iquique	Bus Station	4:50 AM	Santiago, RM	Sur Bus Station	Premium Economy	$42	A Bus from Pluss Chile goes from Bus Station, Iquique (Chile) at 3/25/2026 3:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/26/2026 4:50:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 25h 50m
Ramos Cholele	24h 0m	8:30 AM	Iquique	Bus Station	8:30 AM	Santiago, RM	Terminal San Borja	Premium Economy	$43	A Bus from Ramos Cholele goes from Bus Station, Iquique (Chile) at 3/25/2026 8:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/26/2026 8:30:00 AM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 24h 0m
Pullman San Andres	26h 0m	9:00 AM	Iquique	Bus Station	11:00 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Pullman San Andres goes from Bus Station, Iquique (Chile) at 3/25/2026 9:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/26/2026 11:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 26h 0m

Did you know that if you travel from Iquique to Santiago, RM via La Serena, you can save more than $17? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  25h 10m
  
  0
  
  7:15 PM
  
  Iquique
  Bus Station
  
  1:45 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/26/2026 7:15:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 1:45:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 18h 30m
- FlixBus
  
  6h 25m
  
  0
  
  2:00 PM
  
  La Serena
  Central Bus Station
  
  8:25 PM
  
  Santiago, RM
  Los Libertadores Bus Stop
  
  0
  
  Economy
  
  $15
  
  A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/27/2026 2:00:00 PM to Los Libertadores Bus Stop, Santiago, RM (Chile) arriving at 3/27/2026 8:25:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 25m
Travel time is 1h 10m longer, but you will save $17

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Cormar Bus	25h 20m	7:00 AM	Iquique	Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Bus Station, Iquique (Chile) at 3/26/2026 7:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/27/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 25h 20m
Pluss Chile	25h 50m	3:00 AM	Iquique	Bus Station	4:50 AM	Santiago, RM	Sur Bus Station	Premium Economy	$42	A Bus from Pluss Chile goes from Bus Station, Iquique (Chile) at 3/26/2026 3:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/27/2026 4:50:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 25h 50m
Cikbus Elité	27h 45m	1:45 AM	Iquique	Bus Station	5:30 AM	Santiago, RM	Sur Bus Station	Premium Economy	$44	A Bus from Cikbus Elité goes from Bus Station, Iquique (Chile) at 3/26/2026 1:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/27/2026 5:30:00 AM. 50 Premium Economy ticket for $44 per person are available. Travel duration is 27h 45m
Nueva Andimar Vip	24h 20m	7:15 PM	Iquique	Bus Station	7:35 PM	Santiago, RM	Terminal San Borja	Economy	$44	A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/26/2026 7:15:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/27/2026 7:35:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 24h 20m
Pullman San Andres	26h 0m	9:00 AM	Iquique	Bus Station	11:00 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Pullman San Andres goes from Bus Station, Iquique (Chile) at 3/26/2026 9:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/27/2026 11:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 26h 0m

Did you know that if you travel from Iquique to Santiago, RM via La Serena, you can save more than $21? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  33h 45m
  
  0
  
  9:15 PM
  
  Iquique
  Bus Station
  
  3:45 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/26/2026 9:15:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 3:45:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 18h 30m
- Buses Romani
  
  6h 15m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Terminal San Borja
  
  0
  
  Business
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 3/28/2026 12:45:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 7:00:00 AM. 50 Business ticket for $11 per person are available. Travel duration is 6h 15m
Travel time is 9h 25m longer, but you will save $21

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Cormar Bus	25h 20m	7:00 AM	Iquique	Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Bus Station, Iquique (Chile) at 3/27/2026 7:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 25h 20m
Pluss Chile	25h 0m	11:00 AM	Iquique	Bus Station	12:00 PM	Santiago, RM	Sur Bus Station	Premium Economy	$42	A Bus from Pluss Chile goes from Bus Station, Iquique (Chile) at 3/27/2026 11:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/28/2026 12:00:00 PM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 25h 0m
Nueva Andimar Vip	24h 20m	7:15 PM	Iquique	Bus Station	7:35 PM	Santiago, RM	Terminal San Borja	Economy	$46	A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/27/2026 7:15:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 7:35:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 24h 20m
Pullman San Andres	26h 0m	9:00 AM	Iquique	Bus Station	11:00 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Pullman San Andres goes from Bus Station, Iquique (Chile) at 3/27/2026 9:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 11:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 26h 0m
Ramos Cholele	24h 0m	8:30 AM	Iquique	Bus Station	8:30 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Ramos Cholele goes from Bus Station, Iquique (Chile) at 3/27/2026 8:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 8:30:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 24h 0m

Did you know that if you travel from Iquique to Santiago, RM via La Serena, you can save more than $21? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  33h 45m
  
  0
  
  9:15 PM
  
  Iquique
  Bus Station
  
  3:45 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/26/2026 9:15:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 3:45:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 18h 30m
- Buses Romani
  
  6h 15m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Terminal San Borja
  
  0
  
  Business
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 3/28/2026 12:45:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 7:00:00 AM. 50 Business ticket for $11 per person are available. Travel duration is 6h 15m
Travel time is 9h 45m longer, but you will save $21

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Pluss Chile	25h 0m	11:00 AM	Iquique	Bus Station	12:00 PM	Santiago, RM	Sur Bus Station	Premium Economy	$42	A Bus from Pluss Chile goes from Bus Station, Iquique (Chile) at 3/28/2026 11:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/29/2026 12:00:00 PM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 25h 0m
Nueva Andimar Vip	25h 40m	7:15 PM	Iquique	Bus Station	8:55 PM	Santiago, RM	Los Libertadores Bus Stop	Economy	$47	A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/28/2026 7:15:00 PM to Los Libertadores Bus Stop, Santiago, RM (Chile) arriving at 3/29/2026 8:55:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 25h 40m
Cikbus Elité	27h 45m	1:45 AM	Iquique	Bus Station	5:30 AM	Santiago, RM	Sur Bus Station	Premium Economy	$48	A Bus from Cikbus Elité goes from Bus Station, Iquique (Chile) at 3/28/2026 1:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/29/2026 5:30:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 27h 45m
Pullman San Andres	26h 0m	9:00 AM	Iquique	Bus Station	11:00 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Pullman San Andres goes from Bus Station, Iquique (Chile) at 3/28/2026 9:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/29/2026 11:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 26h 0m
Ramos Cholele	24h 0m	8:30 AM	Iquique	Bus Station	8:30 AM	Santiago, RM	Terminal San Borja	Premium Economy	$48	A Bus from Ramos Cholele goes from Bus Station, Iquique (Chile) at 3/28/2026 8:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/29/2026 8:30:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 24h 0m

Did you know that if you travel from Iquique to Santiago, RM via La Serena, you can save more than $25? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  33h 45m
  
  0
  
  9:15 PM
  
  Iquique
  Bus Station
  
  3:45 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from Nueva Andimar Vip goes from Bus Station, Iquique (Chile) at 3/26/2026 9:15:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 3:45:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 18h 30m
- Buses Romani
  
  6h 15m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Terminal San Borja
  
  0
  
  Business
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 3/28/2026 12:45:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 7:00:00 AM. 50 Business ticket for $11 per person are available. Travel duration is 6h 15m
Travel time is 9h 45m longer, but you will save $25

Best Price Offer: The price for the cheapest bus from Iquique to Santiago, RM is $36 on 4/15/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Iquique and Santiago, RM

See here how frequent the connections between Iquique and Santiago, RM are, during different times and days of the week.

Saturday is the busiest day, with more than 114 daily buses from Iquique to Santiago, RM. Tuesday has instead the fewest connections, with only 79 daily coaches between Iquique and Santiago, RM.

The busiest time of the day is the Afternoon, with 230 buses from Iquique to Santiago, RM, while Night sees the fewest connections between Iquique and Santiago, RM, with 74 offers.

Facts about the bus from Iquique to Santiago, RM

Compare all providers like Pullman San Andres, Pluss Chile and Pullman Bus that travel 90 times every day by bus from Iquique to Santiago, RM in one click! Book your bus ticket from Iquique to Santiago, RM starting from $36!

Cheapest Bus	$36
Fastest Bus	23h 39m
Earliest Bus	7:00 AM
Latest Bus	10:00 PM
Daily Bus Routes	90 Ø
Distance	913.8 miles
Bus Companies	Pullman San Andres, Pluss Chile, Pullman Bus, Cikbus Elité, Cormar Bus, Nueva Andimar Vip, FlixBus, Ramos Cholele and Gentour

Cheapest bus connections from Iquique to Santiago, RM

Every day, 90 buses from 9 bus companies leave Iquique for Santiago, RM: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

$52

Monday 03/23

$43

Tuesday 03/24

$42

Wednesday 03/25

$38

Thursday 03/26

$52

Friday 03/27

$42

Saturday 03/28

$47

Sunday 03/29

$42

Monday 03/30

$38

Tuesday 03/31

$38

Wednesday 04/01

$38

Thursday 04/02

$38

Friday 04/03

$38

Saturday 04/04

$42

Sunday 04/05

$38

Monday 04/06

$52

Tuesday 04/07

$38

Wednesday 04/08

$38

Thursday 04/09

$38

Friday 04/10

$38

Saturday 04/11

$46

Sunday 04/12

$48

Monday 04/13

$38

Tuesday 04/14

$38

Wednesday 04/15

$36

Thursday 04/16

$38

Friday 04/17

$38

Saturday 04/18

The cheapest time to travel from Iquique to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from Iquique to Santiago, RM, for the next 30 days.

With a price starting from $36, Wednesday is the cheapest day for a bus from Iquique to Santiago, RM. Saturday instead is the most expensive day with prices starting from $42.

Night is the cheapest day time for bus tickets from Iquique to Santiago, RM, with $36. Evening is the most expensive time of the day with prices starting from $40.

How to save money travelling from Iquique to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Iquique to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Iquique to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Iquique to Santiago, RM are also emptier.

Beloved bus companies from Iquique to Santiago, RM

These are the most booked bus companies between Iquique to Santiago, RM from our users.

Cormar Bus from Iquique to Santiago, RM

Here you will find the key facts about the Cormar Bus bus route Iquique to Santiago, RM:

Cheapest Price	$38
Fastest Bus	24h 10m
Earliest Bus	7:00 AM
Last Bus	5:30 PM
Daily Connections	3 Ø
Found on	3/22/2026

Pullman Bus from Iquique to Santiago, RM

Here you will find the key facts about the Pullman Bus bus route Iquique to Santiago, RM:

Cheapest Price	$53
Fastest Bus	24h 30m
Earliest Bus	9:00 AM
Last Bus	4:15 PM
Daily Connections	14 Ø
Found on	3/22/2026

Pluss Chile from Iquique to Santiago, RM

Here you will find the key facts about the Pluss Chile bus route Iquique to Santiago, RM:

Cheapest Price	$42
Fastest Bus	24h 15m
Earliest Bus	7:46 AM
Last Bus	7:30 PM
Daily Connections	16 Ø
Found on	3/22/2026

Latest reviews for bus companies on the route Iquique - Santiago, RM

Hernan Vargas, 2/12/2026

El chofer súper choro, pero me sentí seguro por eso… me dejo a cargo de basura y me dejo cambiarme de asiento, pasamos a cenar a las 1 de la mañana, pero mejor que pasar hambre. Me divertí cuando el c ... El chofer súper choro, pero me sentí seguro por eso… me dejo a cargo de basura y me dejo cambiarme de asiento, pasamos a cenar a las 1 de la mañana, pero mejor que pasar hambre. Me divertí cuando el chofer se pelio con una chica que del asiento del al lado, le exigió el sinturon de seguridad, por lo que estaba preocupado por la vida del pasajero. El fin justifica los medios. 10/10. Lo recomiendo como show de standup comedy.

Jorge Souza, 12/24/2024

Pésimo servicio llego re tarde al lugar de origen Retraso 8 horas lentísimo no lo recomiendo para nada

All bus stations and stops in Iquique and Santiago, RM

In the map below, you can see where to find all bus stations in Iquique and Santiago, RM.

Bus Station

Patricio Lynch

Playa Blanca

Esmeralda

Huara

Bajo Molle

Sur Bus Station

Av Libertador Bernardo O'Higgins 3850

Terminal San Borja

San Francisco de Borja 198-180

Terminal Alameda

Av Libertador Bernardo O'Higgins 3750

Terminal Pajaritos

Av. Gral. Óscar Bonilla 5935-5939

Los Héroes Station

Tucapel Jiménez 22

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Iquique to Santiago, RM? Compare all modes of transports from Iquique to Santiago, RM.

Service and Comfort on the bus from Iquique to Santiago, RM

Want to know which seat classes are available on the buses from Iquique to Santiago, RM? Or which bus companies serve the route Iquique to Santiago, RM? Below you will find answers to your questions.

FAQs about the Iquique to Santiago, RM bus

How much does a Iquique Santiago, RM bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $36 and takes 25h 20m to reach Santiago, RM. Compare offers to save money!

How much could I save by comparing buses from Iquique to Santiago, RM?

This route is offered by 9 companies with a range of ticket prices between $36 and $97. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago, RM.

On average, how many connections are available from Iquique to Santiago, RM each day?

Every day, the Iquique to Santiago, RM bus route is served by approximately 90 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Iquique to Santiago, RM take?

The fastest bus from Iquique to Santiago, RM is offered by Gentour and takes 23h 39m. Bus tickets for this connection cost $48. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Iquique to Santiago, RM?

The earliest bus arriving in Santiago, RM from Iquique starts at 7:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Iquique to Santiago, RM?

The latest bus trip departing from Iquique for Santiago, RM starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Iquique Santiago, RM route?

When traveling by bus from Iquique to Santiago, RM, passengers can travel with Pullman San Andres, Pluss Chile and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Iquique and Santiago, RM?

You can check all the direct connections between Iquique and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman San Andres, Pluss Chile and Pullman Bus.

What can I take with me on the Iquique to Santiago, RM bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Iquique Santiago, RM bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Iquique Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Iquique to Santiago, RM on your planned travel date.

How does CheckMyBus find the best bus deals from Iquique to Santiago, RM?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 90 daily trips between Iquique and Santiago, RM. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Iquique to Santiago, RM?

Prices and availability for 90 trips between Iquique and Santiago, RM change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Iquique to Santiago, RM

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Iquique and to Santiago, RM

Here’s an overview of the most popular bus routes to Iquique and to Santiago, RM. Simply click on the connection of your choice, and you will find all the details about your bus route!