Which bus from La Serena to Santiago, RM is the cheapest?

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Compare all timetables for the bus from La Serena to Santiago, RM

Here is a selection of the cheapest bus trips from the schedule from La Serena to Santiago, RM from various bus operators like Cikbus Elité, FlixBus or Pullman Bus for the next days.

today
$9
tomorrow
$13
Saturday
$10
Sunday
$11
Monday
$10
Tuesday
$10
Wednesday
$9

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cikbus Elité 7h 0m 9:30 AM La Serena Central Bus Station 4:30 PM Santiago, RM Terminal San Borja  Business $9
Buses Romani 6h 15m 12:45 AM La Serena Central Bus Station 7:00 AM Santiago, RM Sur Bus Station  Premium Economy $10
FlixBus 6h 5m 6:00 AM La Serena Central Bus Station 12:05 PM Santiago, RM Terminal San Borja  Premium Economy $12
Pullman Bus 6h 30m 2:00 AM La Serena El Sto, 1060 8:30 AM Santiago, RM Terminal San Borja  First Class $13
Pullman San Andres 6h 10m 7:50 AM La Serena Central Bus Station 2:00 PM Santiago, RM Terminal San Borja  First Class $13

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Serena Mar 6h 0m 10:00 AM La Serena Central Bus Station 4:00 PM Santiago, RM Terminal San Borja  First Class $13
Cikbus Elité 6h 0m 8:30 AM La Serena Central Bus Station 2:30 PM Santiago, RM Sur Bus Station  Premium Economy $14
FlixBus 6h 5m 6:00 AM La Serena Central Bus Station 12:05 PM Santiago, RM Terminal San Borja  Economy $15
Condor Bus 6h 30m 3:15 AM La Serena Central Bus Station 9:45 AM Santiago, RM Sur Bus Station  Premium Economy $16
Pullman Bus 6h 30m 5:30 AM La Serena El Sto, 1060 12:00 PM Santiago, RM Terminal San Borja  First Class $16

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 15m 12:45 AM La Serena Central Bus Station 7:00 AM Santiago, RM Sur Bus Station  Premium Economy $10
FlixBus 6h 5m 11:00 AM La Serena Central Bus Station 5:05 PM Santiago, RM Terminal San Borja  Economy $12
Cormar Bus 6h 10m 1:20 PM La Serena Central Bus Station 7:30 PM Santiago, RM Terminal San Borja  First Class $14
Condor Bus 6h 15m 4:50 PM La Serena Central Bus Station 11:05 PM Santiago, RM Sur Bus Station  Premium Economy $15
Cikbus Elité 6h 0m 11:00 AM La Serena Central Bus Station 5:00 PM Santiago, RM Terminal San Borja  First Class $15

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 0m 9:00 AM La Serena Central Bus Station 3:00 PM Santiago, RM Terminal San Borja  Business $11
FlixBus 6h 5m 3:30 PM La Serena Central Bus Station 9:35 PM Santiago, RM Terminal San Borja  Economy $12
Serena Mar 6h 0m 10:00 AM La Serena Central Bus Station 4:00 PM Santiago, RM Terminal San Borja  First Class $13
Cikbus Elité 6h 30m 2:00 AM La Serena Central Bus Station 8:30 AM Santiago, RM Sur Bus Station  Premium Economy $14
Condor Bus 6h 35m 1:45 AM La Serena Central Bus Station 8:20 AM Santiago, RM Sur Bus Station  Premium Economy $15

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 15m 12:45 AM La Serena Central Bus Station 7:00 AM Santiago, RM Sur Bus Station  Premium Economy $10
Turbus 6h 15m 2:30 AM La Serena Avda. Fco de Aguirre Station 8:45 AM Santiago, RM Terminal Alameda  Premium Economy $11
Serena Mar 6h 0m 10:00 AM La Serena Central Bus Station 4:00 PM Santiago, RM Terminal San Borja  First Class $13
Cikbus Elité 7h 0m 9:30 AM La Serena Central Bus Station 4:30 PM Santiago, RM Terminal San Borja  Business $14
Cormar Bus 6h 10m 1:20 PM La Serena Central Bus Station 7:30 PM Santiago, RM Terminal San Borja  First Class $15

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 0m 9:00 AM La Serena Central Bus Station 3:00 PM Santiago, RM Sur Bus Station  Premium Economy $10
Cormar Bus 6h 10m 11:50 PM La Serena Central Bus Station 6:00 AM Santiago, RM Terminal San Borja  Premium Economy $11
Turbus 6h 5m 6:55 AM La Serena Avda. Fco de Aguirre Station 1:00 PM Santiago, RM Terminal Alameda  Premium Economy $11
Cikbus Elité 7h 0m 9:30 AM La Serena Central Bus Station 4:30 PM Santiago, RM Terminal San Borja  Business $14
FlixBus 6h 5m 6:00 AM La Serena Central Bus Station 12:05 PM Santiago, RM Terminal San Borja  Economy $15

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cikbus Elité 7h 0m 9:30 AM La Serena Central Bus Station 4:30 PM Santiago, RM Terminal San Borja  Business $9
Buses Romani 6h 15m 12:45 AM La Serena Central Bus Station 7:00 AM Santiago, RM Sur Bus Station  Premium Economy $10
Condor Bus 6h 50m 3:15 AM La Serena Central Bus Station 10:05 AM Santiago, RM Sur Bus Station  Premium Economy $11
Cormar Bus 6h 20m 11:50 AM La Serena Central Bus Station 6:10 PM Santiago, RM Terminal San Borja  Premium Economy $11
FlixBus 6h 5m 6:00 AM La Serena Central Bus Station 12:05 PM Santiago, RM Terminal San Borja  Economy $11

Best Price Offer: The price for the cheapest bus from La Serena to Santiago, RM is $8 on 12/25/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between La Serena and Santiago, RM

See here how frequent the connections between La Serena and Santiago, RM are, during different times and days of the week.
Wednesday is the busiest day, with more than 318 daily buses from La Serena to Santiago, RM. Saturday has instead the fewest connections, with only 243 daily coaches between La Serena and Santiago, RM.
The busiest time of the day is the Night, with 651 buses from La Serena to Santiago, RM, while Evening sees the fewest connections between La Serena and Santiago, RM, with 301 offers.

Facts about the bus from La Serena to Santiago, RM

Compare all providers like Cikbus Elité, FlixBus and Pullman Bus that travel 282 times every day by bus from La Serena to Santiago, RM in one click! Book your bus ticket from La Serena to Santiago, RM starting from $8!

Cheapest Bus $8
Fastest Bus 5h 40m
Earliest Bus 12:05 AM
Latest Bus 11:59 PM
Daily Bus Routes 282 Ø
Distance 247.0 miles
Bus Companies Cikbus Elité, FlixBus, Pullman Bus, Pluss Chile, Turbus, Pullman San Andres, Buses Romani, Condor Bus, Cormar Bus, Nueva Andimar Vip and 2 more.

Cheapest bus connections from La Serena to Santiago, RM

Every day, 282 buses from 12 bus companies leave La Serena for Santiago, RM: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
$13
Friday 12/05
$31
Saturday 12/06
$26
Sunday 12/07
$12
Monday 12/08
$10
Tuesday 12/09
$10
Wednesday 12/10
$9
Thursday 12/11
$10
Friday 12/12
$11
Saturday 12/13
$13
Sunday 12/14
$13
Monday 12/15
$11
Tuesday 12/16
$10
Wednesday 12/17
$8
Thursday 12/18
$8
Friday 12/19
$11
Saturday 12/20
$11
Sunday 12/21
$10
Monday 12/22
$11
Tuesday 12/23
$8
Wednesday 12/24
$8
Thursday 12/25
$8
Friday 12/26
$27
Saturday 12/27

The cheapest time to travel from La Serena to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from La Serena to Santiago, RM, for the next 30 days.
With a price starting from $8, Thursday is the cheapest day for a bus from La Serena to Santiago, RM. Friday instead is the most expensive day with prices starting from $11.
Night is the cheapest day time for bus tickets from La Serena to Santiago, RM, with $8. Afternoon is the most expensive time of the day with prices starting from $11.

How to save money travelling from La Serena to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from La Serena to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from La Serena to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from La Serena to Santiago, RM are also emptier.

Beloved bus companies from La Serena to Santiago, RM

These are the most booked bus companies between La Serena to Santiago, RM from our users.

Latest reviews for bus companies on the route La Serena - Santiago, RM

Pluss Chile
Claudia , 10/23/2025

El bus venía de Calama y salió con una hora de retraso.

Pluss Chile
Luis ig, 10/5/2025
Viaje en salón cama de la serena a Santiago y el bus salió una hora más tarde adema la máquina estaba hedionda y el asiento de reclinaba solo y el posa piernas estaba vencido por lo que todo el viaje ... Viaje en salón cama de la serena a Santiago y el bus salió una hora más tarde adema la máquina estaba hedionda y el asiento de reclinaba solo y el posa piernas estaba vencido por lo que todo el viaje me estuvo golpeando las piernas, pésimo el viaje.
Pluss Chile
Esteban Guerrero, 1/29/2025

Compré un pasaje de 6 horas en salón premium adelante en el parabrisas no había nada de espacio. Ultima vez que viajo en plus chile

All bus stations and stops in La Serena and Santiago, RM

In the map below, you can see where to find all bus stations in La Serena and Santiago, RM.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from La Serena to Santiago, RM? Compare all modes of transports from La Serena to Santiago, RM.

Service and Comfort on the bus from La Serena to Santiago, RM

Want to know which seat classes are available on the buses from La Serena to Santiago, RM? Or which bus companies serve the route La Serena to Santiago, RM? Below you will find answers to your questions.

FAQs about the La Serena to Santiago, RM bus

How much does a La Serena Santiago, RM bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $8 and takes 7h 0m to reach Santiago, RM. Compare offers to save money!

How much could I save by comparing buses from La Serena to Santiago, RM?

This route is offered by 12 companies with a range of ticket prices between $8 and $39. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago, RM.

On average, how many connections are available from La Serena to Santiago, RM each day?

Every day, the La Serena to Santiago, RM bus route is served by approximately 282 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from La Serena to Santiago, RM take?

The fastest bus from La Serena to Santiago, RM is offered by Turbus and takes 5h 40m. Bus tickets for this connection cost $33. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from La Serena to Santiago, RM?

The earliest bus arriving in Santiago, RM from La Serena starts at 12:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from La Serena to Santiago, RM?

The latest bus trip departing from La Serena for Santiago, RM starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the La Serena Santiago, RM route?

When traveling by bus from La Serena to Santiago, RM, passengers can travel with Cikbus Elité, FlixBus and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between La Serena and Santiago, RM?

You can check all the direct connections between La Serena and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Cikbus Elité, FlixBus and Pullman Bus.

What can I take with me on the La Serena to Santiago, RM bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the La Serena Santiago, RM bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Santiago, RM on your planned travel date.

Available seat classes which are offered on the bus route La Serena to Santiago, RM

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to La Serena and to Santiago, RM

Here’s an overview of the most popular bus routes to La Serena and to Santiago, RM. Simply click on the connection of your choice, and you will find all the details about your bus route!

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