Bus Rancagua to La Serena: Compare prices and save money

Compare all timetables for the bus from Rancagua to La Serena

Here is a selection of the cheapest bus trips from the schedule from Rancagua to La Serena from various bus operators like Turbus for the next days.

today

$49

tomorrow

$38

Wednesday

$36

Thursday

$49

Friday

$30

Saturday

$49

Sunday

$30

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	20h 10m	10:00 AM	Rancagua	Rodoviario Rancagua	6:10 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/20/2026 10:00:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 6:10:00 AM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 20h 10m
Turbus	17h 55m	10:30 PM	Rancagua	Rodoviario Rancagua	4:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/20/2026 10:30:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 4:25:00 PM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 17h 55m
Turbus	18h 0m	12:45 PM	Rancagua	Rodoviario Rancagua	6:45 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$51	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/20/2026 12:45:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 6:45:00 AM. 50 Premium Economy ticket for $51 per person are available. Travel duration is 18h 0m
Turbus	18h 15m	6:30 PM	Rancagua	Rodoviario Rancagua	12:45 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$51	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/20/2026 6:30:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 12:45:00 PM. 50 Premium Economy ticket for $51 per person are available. Travel duration is 18h 15m
Turbus	17h 55m	8:50 PM	Rancagua	Rodoviario Rancagua	2:45 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$51	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/20/2026 8:50:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 2:45:00 PM. 50 Premium Economy ticket for $51 per person are available. Travel duration is 17h 55m

Did you know that if you travel from Rancagua to La Serena via Santiago, RM, you can save more than $33? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  6h 40m
  
  0
  
  9:00 AM
  
  Rancagua
  Bus Stop
  
  9:59 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Economy
  
  $3
  
  A Bus from Nueva Andimar Vip goes from Bus Stop, Rancagua (Chile) at 4/21/2026 9:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2026 9:59:00 AM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 59m
- FlixBus
  
  5h 35m
  
  0
  
  10:05 AM
  
  Santiago, RM
  Los Libertadores Bus Stop
  
  3:40 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Los Libertadores Bus Stop, Santiago, RM (Chile) at 4/21/2026 10:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 4/21/2026 3:40:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 35m
Travel Time is 11h 15m shorter, and you will save $33

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	11h 20m	1:25 AM	Rancagua	Rodoviario Rancagua	12:45 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$38	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/21/2026 1:25:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 12:45:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 11h 20m
Turbus	11h 30m	3:15 AM	Rancagua	Rodoviario Rancagua	2:45 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$38	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/21/2026 3:15:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 2:45:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 11h 30m
Turbus	11h 20m	1:05 AM	Rancagua	Rodoviario Rancagua	12:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$41	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/21/2026 1:05:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 12:25:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 20m
Turbus	11h 15m	12:35 AM	Rancagua	Rodoviario Rancagua	11:50 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$48	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/21/2026 12:35:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 11:50:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 11h 15m
Turbus	11h 50m	4:35 AM	Rancagua	Rodoviario Rancagua	4:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$51	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/21/2026 4:35:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/21/2026 4:25:00 PM. 50 Premium Economy ticket for $51 per person are available. Travel duration is 11h 50m

Did you know that if you travel from Rancagua to La Serena via Santiago, RM, you can save more than $22? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  6h 40m
  
  0
  
  9:00 AM
  
  Rancagua
  Bus Stop
  
  9:59 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Economy
  
  $3
  
  A Bus from Nueva Andimar Vip goes from Bus Stop, Rancagua (Chile) at 4/21/2026 9:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2026 9:59:00 AM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 59m
- FlixBus
  
  5h 35m
  
  0
  
  10:05 AM
  
  Santiago, RM
  Los Libertadores Bus Stop
  
  3:40 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Los Libertadores Bus Stop, Santiago, RM (Chile) at 4/21/2026 10:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 4/21/2026 3:40:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 35m
Travel Time is 4h 35m shorter, and you will save $22

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	11h 55m	8:00 AM	Rancagua	Rodoviario Rancagua	7:55 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$36	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/22/2026 8:00:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/22/2026 7:55:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 55m
Turbus	11h 15m	7:30 PM	Rancagua	Rodoviario Rancagua	6:45 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$36	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/22/2026 7:30:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/23/2026 6:45:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 15m
Turbus	11h 10m	9:45 PM	Rancagua	Rodoviario Rancagua	8:55 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$36	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/22/2026 9:45:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/23/2026 8:55:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 10m
Turbus	11h 50m	4:35 AM	Rancagua	Rodoviario Rancagua	4:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$38	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/22/2026 4:35:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/22/2026 4:25:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 11h 50m
Turbus	11h 50m	9:10 AM	Rancagua	Rodoviario Rancagua	9:00 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$38	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/22/2026 9:10:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/22/2026 9:00:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 11h 50m

Did you know that if you travel from Rancagua to La Serena via Santiago, RM, you can save more than $20? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  6h 40m
  
  0
  
  9:00 AM
  
  Rancagua
  Bus Stop
  
  9:59 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Economy
  
  $3
  
  A Bus from Nueva Andimar Vip goes from Bus Stop, Rancagua (Chile) at 4/21/2026 9:00:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2026 9:59:00 AM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 59m
- FlixBus
  
  5h 35m
  
  0
  
  10:05 AM
  
  Santiago, RM
  Los Libertadores Bus Stop
  
  3:40 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Los Libertadores Bus Stop, Santiago, RM (Chile) at 4/21/2026 10:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 4/21/2026 3:40:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 35m
Travel Time is 4h 30m shorter, and you will save $20

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	20h 10m	10:00 AM	Rancagua	Rodoviario Rancagua	6:10 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/23/2026 10:00:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 6:10:00 AM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 20h 10m
Turbus	18h 0m	12:45 PM	Rancagua	Rodoviario Rancagua	6:45 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/23/2026 12:45:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 6:45:00 AM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 18h 0m
Turbus	18h 15m	6:30 PM	Rancagua	Rodoviario Rancagua	12:45 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/23/2026 6:30:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 12:45:00 PM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 18h 15m
Turbus	17h 40m	9:00 PM	Rancagua	Rodoviario Rancagua	2:40 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/23/2026 9:00:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 2:40:00 PM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 17h 40m
Turbus	17h 55m	10:30 PM	Rancagua	Rodoviario Rancagua	4:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/23/2026 10:30:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 4:25:00 PM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 17h 55m

Did you know that if you travel from Rancagua to La Serena via Santiago, RM, you can save more than $35? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  7h 20m
  
  0
  
  1:30 PM
  
  Rancagua
  Bus Stop
  
  2:29 PM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Economy
  
  $3
  
  A Bus from Nueva Andimar Vip goes from Bus Stop, Rancagua (Chile) at 4/24/2026 1:30:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/24/2026 2:29:00 PM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 59m
- Pluss Chile
  
  6h 20m
  
  0
  
  2:30 PM
  
  Santiago, RM
  Sur Bus Station
  
  8:50 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 4/24/2026 2:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 4/24/2026 8:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 20m
Travel Time is 10h 20m shorter, and you will save $35

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	11h 15m	12:35 AM	Rancagua	Rodoviario Rancagua	11:50 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$30	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/24/2026 12:35:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 11:50:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 15m
Turbus	11h 20m	1:05 AM	Rancagua	Rodoviario Rancagua	12:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$30	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/24/2026 1:05:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 12:25:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 20m
Turbus	11h 50m	9:10 AM	Rancagua	Rodoviario Rancagua	9:00 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$30	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/24/2026 9:10:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 9:00:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
Turbus	11h 15m	7:30 PM	Rancagua	Rodoviario Rancagua	6:45 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$30	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/24/2026 7:30:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/25/2026 6:45:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 15m
Turbus	11h 20m	1:25 AM	Rancagua	Rodoviario Rancagua	12:45 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$36	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/24/2026 1:25:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/24/2026 12:45:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 20m

Did you know that if you travel from Rancagua to La Serena via Santiago, RM, you can save more than $16? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  7h 20m
  
  0
  
  1:30 PM
  
  Rancagua
  Bus Stop
  
  2:29 PM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Economy
  
  $3
  
  A Bus from Nueva Andimar Vip goes from Bus Stop, Rancagua (Chile) at 4/24/2026 1:30:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/24/2026 2:29:00 PM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 59m
- Pluss Chile
  
  6h 20m
  
  0
  
  2:30 PM
  
  Santiago, RM
  Sur Bus Station
  
  8:50 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 4/24/2026 2:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 4/24/2026 8:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 20m
Travel Time is 3h 55m shorter, and you will save $16

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	20h 10m	10:00 AM	Rancagua	Rodoviario Rancagua	6:10 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/25/2026 10:00:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 6:10:00 AM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 20h 10m
Turbus	18h 0m	12:45 PM	Rancagua	Rodoviario Rancagua	6:45 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/25/2026 12:45:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 6:45:00 AM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 18h 0m
Turbus	18h 15m	6:30 PM	Rancagua	Rodoviario Rancagua	12:45 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/25/2026 6:30:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 12:45:00 PM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 18h 15m
Turbus	17h 55m	9:00 PM	Rancagua	Rodoviario Rancagua	2:55 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/25/2026 9:00:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 2:55:00 PM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 17h 55m
Turbus	17h 55m	10:30 PM	Rancagua	Rodoviario Rancagua	4:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$49	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/25/2026 10:30:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 4:25:00 PM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 17h 55m

Did you know that if you travel from Rancagua to La Serena via Santiago, RM, you can save more than $35? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  7h 20m
  
  0
  
  1:30 PM
  
  Rancagua
  Bus Stop
  
  2:29 PM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Economy
  
  $3
  
  A Bus from Nueva Andimar Vip goes from Bus Stop, Rancagua (Chile) at 4/24/2026 1:30:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/24/2026 2:29:00 PM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 59m
- Pluss Chile
  
  6h 20m
  
  0
  
  2:30 PM
  
  Santiago, RM
  Sur Bus Station
  
  8:50 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 4/24/2026 2:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 4/24/2026 8:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 20m
Travel Time is 10h 35m shorter, and you will save $35

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	11h 20m	1:05 AM	Rancagua	Rodoviario Rancagua	12:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$30	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/26/2026 1:05:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 12:25:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 20m
Turbus	11h 20m	1:25 AM	Rancagua	Rodoviario Rancagua	12:45 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$30	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/26/2026 1:25:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 12:45:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 20m
Turbus	11h 15m	12:35 AM	Rancagua	Rodoviario Rancagua	11:50 AM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$36	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/26/2026 12:35:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 11:50:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 15m
Turbus	11h 35m	3:20 AM	Rancagua	Rodoviario Rancagua	2:55 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$36	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/26/2026 3:20:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 2:55:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 35m
Turbus	11h 50m	4:35 AM	Rancagua	Rodoviario Rancagua	4:25 PM	La Serena	Avda. Fco de Aguirre Station	Premium Economy	$51	A Bus from Turbus goes from Rodoviario Rancagua, Rancagua (Chile) at 4/26/2026 4:35:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 4/26/2026 4:25:00 PM. 50 Premium Economy ticket for $51 per person are available. Travel duration is 11h 50m

Did you know that if you travel from Rancagua to La Serena via Santiago, RM, you can save more than $16? You can find the corresponding connections below.
- Nueva Andimar Vip
  
  7h 20m
  
  0
  
  1:30 PM
  
  Rancagua
  Bus Stop
  
  2:29 PM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Economy
  
  $3
  
  A Bus from Nueva Andimar Vip goes from Bus Stop, Rancagua (Chile) at 4/24/2026 1:30:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/24/2026 2:29:00 PM. 50 Economy ticket for $3 per person are available. Travel duration is 0h 59m
- Pluss Chile
  
  6h 20m
  
  0
  
  2:30 PM
  
  Santiago, RM
  Sur Bus Station
  
  8:50 PM
  
  La Serena
  Central Bus Station
  
  0
  
  Premium Economy
  
  $12
  
  A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 4/24/2026 2:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 4/24/2026 8:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 20m
Travel Time is 3h 55m shorter, and you will save $16

Best Price Offer: The price for the cheapest bus from Rancagua to La Serena is $30 on 4/24/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Rancagua and La Serena

See here how frequent the connections between Rancagua and La Serena are, during different times and days of the week.

Sunday is the busiest day, with more than 13 daily buses from Rancagua to La Serena. Monday has instead the fewest connections, with only 6 daily coaches between Rancagua and La Serena.

The busiest time of the day is the Evening, with 27 buses from Rancagua to La Serena, while Morning sees the fewest connections between Rancagua and La Serena, with 11 offers.

Facts about the bus from Rancagua to La Serena

Compare all providers like Turbus that travel 10 times every day by bus from Rancagua to La Serena in one click! Book your bus ticket from Rancagua to La Serena starting from $30!

Cheapest Bus	$30
Fastest Bus	11h 10m
Earliest Bus	10:00 AM
Latest Bus	11:35 PM
Daily Bus Routes	10 Ø
Distance	296.4 miles
Bus Companies	Turbus

Cheapest bus connections from Rancagua to La Serena

Every day, 10 buses from 1 bus companies leave Rancagua for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$49

Tuesday 04/21

$38

Wednesday 04/22

$36

Thursday 04/23

$49

Friday 04/24

$30

Saturday 04/25

$49

Sunday 04/26

$30

Monday 04/27

$49

Tuesday 04/28

$49

Wednesday 04/29

$56

Thursday 04/30

$51

Friday 05/01

$30

Saturday 05/02

$56

Sunday 05/03

$66

Monday 05/04

$30

Tuesday 05/05

$30

Wednesday 05/06

$51

Thursday 05/07

$30

Friday 05/08

$30

Saturday 05/09

$30

Sunday 05/10

$51

Monday 05/11

$51

Tuesday 05/12

$51

Wednesday 05/13

$51

Thursday 05/14

$30

Friday 05/15

$51

Saturday 05/16

The cheapest time to travel from Rancagua to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Rancagua to La Serena, for the next 30 days.

With a price starting from $30, Sunday is the cheapest day for a bus from Rancagua to La Serena. Wednesday instead is the most expensive day with prices starting from $36.

Morning is the cheapest day time for bus tickets from Rancagua to La Serena, with $30. Afternoon is the most expensive time of the day with prices starting from $36.

How to save money travelling from Rancagua to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rancagua to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rancagua to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rancagua to La Serena are also emptier.

All bus stations and stops in Rancagua and La Serena

In the map below, you can see where to find all bus stations in Rancagua and La Serena.

Terminal O´Higgins

Libertador Bernardo O'Higgins 34

Sur

Manuel Montt

Estado

Ocarrol Bus Station

Parque Safari

Avda. Fco de Aguirre Station

Avenida Francisco de Aguirre 410

Central Bus Station

Avenida El Santo 1475

El Sto, 1060

Rotonda

terminal de buses covalle bus

Service and Comfort on the bus from Rancagua to La Serena

Want to know which seat classes are available on the buses from Rancagua to La Serena? Or which bus companies serve the route Rancagua to La Serena? Below you will find answers to your questions.

FAQs about the Rancagua to La Serena bus

How much does a Rancagua La Serena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $30 and takes 11h 15m to reach La Serena. Compare offers to save money!

How much could I save by comparing buses from Rancagua to La Serena?

This route is offered by 1 companies with a range of ticket prices between $30 and $71. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.

On average, how many connections are available from Rancagua to La Serena each day?

Every day, the Rancagua to La Serena bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rancagua to La Serena take?

The fastest bus from Rancagua to La Serena is offered by Turbus and takes 11h 10m. Bus tickets for this connection cost $55. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rancagua to La Serena?

The earliest bus arriving in La Serena from Rancagua starts at 10:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rancagua to La Serena?

The latest bus trip departing from Rancagua for La Serena starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rancagua La Serena route?

When traveling by bus from Rancagua to La Serena, passengers can travel with Turbus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rancagua and La Serena?

You can check all the direct connections between Rancagua and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Turbus.

What can I take with me on the Rancagua to La Serena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rancagua La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rancagua La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rancagua to La Serena on your planned travel date.

How does CheckMyBus find the best bus deals from Rancagua to La Serena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Rancagua and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rancagua to La Serena?

Prices and availability for 10 trips between Rancagua and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rancagua to La Serena

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rancagua and to La Serena

Here’s an overview of the most popular bus routes to Rancagua and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!