Bus from Antofagasta to La Serena from $24

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Compare all timetables for the bus from Antofagasta to La Serena

Here is a selection of the cheapest bus trips from the schedule from Antofagasta to La Serena from various bus operators like Pluss Chile, Pullman Bus or Pullman San Andres for the next days.

today
from $24
tomorrow
from $24
Sunday
from $28
Monday
from $26
Tuesday
from $26
Wednesday
from $26
Thursday
from $28

Cheapest bus trips today

Prices are for one way and one person
  • Pluss Chile
    11h 35m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:50 PM
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    $24
  • Nueva Andimar Vip
    12h 20m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:55 PM
    La Serena
    Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $28
  • Turbus
    11h 55m
    0
    8:00 AM
    Antofagasta
    Terminal Buses Camus
    7:55 PM
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    $28
  • Pullman Bus
    11h 20m
    0
    9:00 PM
    Antofagasta
    Terminal Buses Camus
    8:20 AM
    La Serena
    El Sto, 1060
    0
    Pullman Bus
    First Class
    $30
  • Cormar Bus
    10h 30m
    0
    9:45 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:15 AM
    La Serena
    Bus Station
    0
    Cormar Bus
    First Class
    $34

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Pluss Chile
    11h 35m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:50 PM
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    $24
  • Turbus
    12h 15m
    0
    4:30 PM
    Antofagasta
    Terminal Buses Camus
    4:45 AM
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    $24
  • Nueva Andimar Vip
    12h 20m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:55 PM
    La Serena
    Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $28
  • Cikbus Elité
    11h 20m
    0
    1:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    12:30 PM
    La Serena
    Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman Bus
    11h 20m
    0
    9:00 PM
    Antofagasta
    Terminal Buses Camus
    8:20 AM
    La Serena
    El Sto, 1060
    0
    Pullman Bus
    First Class
    $30

Cheapest bus trips Sunday

Prices are for one way and one person
  • Nueva Andimar Vip
    12h 20m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:55 PM
    La Serena
    Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $28
  • Turbus
    11h 15m
    0
    12:20 AM
    Antofagasta
    Terminal Buses Camus
    11:35 AM
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    $28
  • Cikbus Elité
    11h 20m
    0
    1:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    12:30 PM
    La Serena
    Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman Bus
    11h 20m
    0
    9:00 PM
    Antofagasta
    Terminal Buses Camus
    8:20 AM
    La Serena
    El Sto, 1060
    0
    Pullman Bus
    First Class
    $30
  • Pullman San Andres
    11h 30m
    0
    5:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    5:00 AM
    La Serena
    Bus Station
    0
    Pullman San Andres
    Premium Economy
    $32

Cheapest bus trips Monday

Prices are for one way and one person
  • Nueva Andimar Vip
    12h 20m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:55 PM
    La Serena
    Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $26
  • Pluss Chile
    11h 35m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:50 PM
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Turbus
    11h 15m
    0
    12:20 AM
    Antofagasta
    Terminal Buses Camus
    11:35 AM
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    $28
  • Cikbus Elité
    11h 20m
    0
    1:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    12:30 PM
    La Serena
    Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman Bus
    11h 20m
    0
    9:00 PM
    Antofagasta
    Terminal Buses Camus
    8:20 AM
    La Serena
    El Sto, 1060
    0
    Pullman Bus
    First Class
    $30

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Nueva Andimar Vip
    12h 20m
    0
    9:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    9:50 AM
    La Serena
    Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $26
  • Cormar Bus
    11h 30m
    0
    11:30 PM
    Antofagasta
    Terminal Buses Camus
    11:00 AM
    La Serena
    Bus Station
    0
    Cormar Bus
    Premium Economy
    $27
  • Turbus
    11h 20m
    0
    1:10 AM
    Antofagasta
    Terminal Buses Camus
    12:30 PM
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    $28
  • Pullman San Andres
    11h 30m
    0
    11:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    11:00 AM
    La Serena
    Bus Station
    0
    Pullman San Andres
    Premium Economy
    $35
  • Pullman Bus
    11h 50m
    0
    12:30 AM
    Antofagasta
    Terminal Buses Camus
    12:20 PM
    La Serena
    El Sto, 1060
    0
    Pullman Bus
    First Class
    $43

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Nueva Andimar Vip
    12h 20m
    0
    3:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    3:55 PM
    La Serena
    Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $26
  • Pluss Chile
    11h 35m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:50 PM
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Cikbus Elité
    11h 15m
    0
    12:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    12:00 PM
    La Serena
    Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman Bus
    11h 35m
    0
    8:30 PM
    Antofagasta
    Terminal Buses Camus
    8:05 AM
    La Serena
    El Sto, 1060
    0
    Pullman Bus
    First Class
    $32
  • Cormar Bus
    11h 20m
    0
    10:50 PM
    Antofagasta
    Terminal Buses Camus
    10:10 AM
    La Serena
    Bus Station
    0
    Cormar Bus
    First Class
    $35

Cheapest bus trips Thursday

Prices are for one way and one person
  • Pluss Chile
    11h 35m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:50 PM
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Pullman Bus
    11h 20m
    0
    9:00 AM
    Antofagasta
    Terminal Buses Camus
    8:20 PM
    La Serena
    El Sto, 1060
    0
    Pullman Bus
    First Class
    $32
  • Cormar Bus
    10h 30m
    0
    9:45 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:15 AM
    La Serena
    Bus Station
    0
    Cormar Bus
    First Class
    $34
  • Turbus
    11h 15m
    0
    12:20 AM
    Antofagasta
    Terminal Buses Camus
    11:35 AM
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    $38
  • Pullman San Andres
    11h 30m
    0
    1:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    1:00 PM
    La Serena
    Bus Station
    0
    Pullman San Andres
    First Class
    $41

Frequency of bus connections between Antofagasta and La Serena

See here how frequent the connections between Antofagasta and La Serena are, during different times and days of the week.
Wednesday is the busiest day, with more than 118 daily buses from Antofagasta to La Serena. Tuesday has instead the fewest connections, with only 60 daily coaches between Antofagasta and La Serena.
The busiest time of the day is the Evening, with 268 buses from Antofagasta to La Serena, while Morning sees the fewest connections between Antofagasta and La Serena, with 46 offers.

Facts about the bus from Antofagasta to La Serena

Compare all providers like Pluss Chile, Pullman Bus and Pullman San Andres that travel 84 times every day by bus from Antofagasta to La Serena in one click! Book your bus ticket from Antofagasta to La Serena starting from $24!

Cheapest Bus $24
Fastest Bus 10h 30m
Earliest Bus 12:15 AM
Latest Bus 11:30 PM
Daily Bus Routes 84 Ø
Distance 435.4 miles
Bus Companies Pluss Chile, Pullman Bus, Pullman San Andres, Turbus, Cikbus Elité, Nueva Andimar Vip and Cormar Bus

Cheapest bus connections from Antofagasta to La Serena

Every day, 84 buses from 7 bus companies leave Antofagasta for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/27/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
Wednesday 06/25
Thursday 06/26
Friday 06/27
$24
Saturday 06/28
$24
Sunday 06/29
$28
Monday 06/30
$28
Tuesday 07/01
$26
Wednesday 07/02
$32
Thursday 07/03
$28
Friday 07/04
$27
Saturday 07/05
$36
Sunday 07/06
$42
Monday 07/07
$24
Tuesday 07/08
$22
Wednesday 07/09
$22
Thursday 07/10
$22
Friday 07/11
$19
Saturday 07/12
$22
Sunday 07/13
$36
Monday 07/14
$22
Tuesday 07/15
$22
Wednesday 07/16
$22
Thursday 07/17
$22
Friday 07/18
$22
Saturday 07/19

The cheapest time to travel from Antofagasta to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to La Serena, for the next 30 days.
With a price starting from $24, Friday is the cheapest day for a bus from Antofagasta to La Serena. Sunday instead is the most expensive day with prices starting from $28.
Afternoon is the cheapest day time for bus tickets from Antofagasta to La Serena, with $24. Morning is the most expensive time of the day with prices starting from $28.

How to save money travelling from Antofagasta to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Antofagasta to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Antofagasta to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Antofagasta to La Serena are also emptier.

Latest reviews for bus companies on the route Antofagasta - La Serena

Cikbus Elité
Alfonso fuentes , 3/22/2025
Muy mala puntualidad ya que teniamos que salir a las 23:30 horas desde antofagasta y terminamos saliendo a las 12 de la madrugada, ademas de eso el bus venia por gran parte del trayecto a mas de 120 k ... Muy mala puntualidad ya que teniamos que salir a las 23:30 horas desde antofagasta y terminamos saliendo a las 12 de la madrugada, ademas de eso el bus venia por gran parte del trayecto a mas de 120 kmh, ademas de eso se quedan haciendo tiempo en chañaral para poder llegar en el horario indicado ademas de eso me cambiaron el pasaje en 2 oportunidades por problemas con sus maquinas por nada del mundo compren pasajes en cikbus

All bus stations and stops in Antofagasta and La Serena

In the map below, you can see where to find all bus stations in Antofagasta and La Serena.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Antofagasta to La Serena? Compare all modes of transports from Antofagasta to La Serena.

Service and Comfort on the bus from Antofagasta to La Serena

Want to know which seat classes are available on the buses from Antofagasta to La Serena? Or which bus companies serve the route Antofagasta to La Serena? Below you will find answers to your questions.

FAQs about the Antofagasta to La Serena bus

How much does a Antofagasta La Serena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $24 and takes 11h 35m to reach La Serena. Compare offers to save money!

How much could I save by comparing buses from Antofagasta to La Serena?

This route is offered by 7 companies with a range of ticket prices between $24 and $52. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.

On average, how many connections are available from Antofagasta to La Serena each day?

Every day, the Antofagasta to La Serena bus route is served by approximately 84 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Antofagasta to La Serena take?

The fastest bus from Antofagasta to La Serena is offered by Cormar Bus and takes 10h 30m. Bus tickets for this connection cost $34. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Antofagasta to La Serena?

The earliest bus arriving in La Serena from Antofagasta starts at 12:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Antofagasta to La Serena?

The latest bus trip departing from Antofagasta for La Serena starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Antofagasta La Serena route?

When traveling by bus from Antofagasta to La Serena, passengers can travel with Pluss Chile, Pullman Bus and Pullman San Andres. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Antofagasta and La Serena?

You can check all the direct connections between Antofagasta and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pluss Chile, Pullman Bus and Pullman San Andres.

What can I take with me on the Antofagasta to La Serena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Antofagasta La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to La Serena on your planned travel date.

Available seat classes which are offered on the bus route Antofagasta to La Serena

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to La Serena

Here’s an overview of the most popular bus routes to Antofagasta and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Calama to Antofagasta Bus from Calama to Antofagasta
Buses Iquique - Antofagasta Buses Iquique - Antofagasta
Buses Arica, AP to Antofagasta Buses Arica, AP to Antofagasta
Bus Cochabamba to Antofagasta Bus Cochabamba to Antofagasta
From Valparaíso (CL) to La Serena bus From Valparaíso (CL) to La Serena bus
Buses to La Serena from Santiago, RM Buses to La Serena from Santiago, RM
Buses Viña del Mar - La Serena Buses Viña del Mar - La Serena
Buses to La Serena from Calama Buses to La Serena from Calama
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