What is the best way to travel from Santiago, RM to Antofagasta?
Looking for a trip? Compare all the available Flights and Buses for the journey to Antofagasta from Santiago, RM. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 13 available companies to find your perfect trip!
What is the cheapest way to reach Antofagasta from Santiago, RM?
You can get to Antofagasta with just $26 by taking a Flight from Sky Airline, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/22/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/23/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Cikbus Elité19h 5m01:30 PMSantiago, RMSur Bus Station8:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 3/22/2026 1:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 8:35:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 19h 5m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/22/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Gentour16h 30m06:30 PMSantiago, RMTerminal San Borja11:00 AMAntofagastaMaipú0Premium EconomyA Bus from Gentour goes from Terminal San Borja, Santiago, RM (Chile) at 3/22/2026 6:30:00 PM to Maipú, Antofagasta (Chile) arriving at 3/23/2026 11:00:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 16h 30m
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Chile Bus19h 0m02:00 PMSantiago, RMTerminal San Borja9:00 AMAntofagastaCarlos Oviedo Cavada Bus Station0First ClassA Bus from Chile Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/22/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 9:00:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 19h 0m
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JetSmart25h 59m08:48 AMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 8:48:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:47:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 25h 59m
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LAN Airlines26h 46m08:01 AMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 8:01:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:47:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 26h 46m
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LAN Perú4h 47m06:00 AMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 6:00:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 10:47:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 4h 47m
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Sky Airline24h 27m010:20 AMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 10:20:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:47:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 24h 27m
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LATAM Brasil20h 42m02:05 PMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 2:05:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:47:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 20h 42m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/23/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/24/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/23/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Chile Bus19h 10m02:00 PMSantiago, RMTerminal San Borja9:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0First ClassA Bus from Chile Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/23/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 9:10:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 19h 10m
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FlixBus18h 35m09:00 AMSantiago, RMTerminal San Borja3:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/23/2026 9:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 3:35:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 18h 35m
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Cikbus Elité19h 0m07:30 AMSantiago, RMSur Bus Station2:30 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 3/23/2026 7:30:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 2:30:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 19h 0m
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JetSmart2h 4m07:04 AMSantiago de Chile AirportSantiago de Chile Airport9:08 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 7:04:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 9:08:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 2h 4m
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Sky Airline10h 47m08:24 AMSantiago de Chile AirportSantiago de Chile Airport7:11 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 8:24:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 7:11:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 10h 47m
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LAN Airlines2h 0m08:52 PMSantiago de Chile AirportSantiago de Chile Airport10:52 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 8:52:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:52:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 2h 0m
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LATAM Brasil2h 0m08:52 PMSantiago de Chile AirportSantiago de Chile Airport10:52 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 8:52:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:52:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 2h 0m
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LAN Perú1h 59m04:48 AMSantiago de Chile AirportSantiago de Chile Airport6:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 4:48:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 6:47:00 AM. 50 Economy ticket for $234 per person are available. Travel duration is 1h 59m
Cheapest Buses Monday
Cheapest Flights Monday
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Nueva Andimar Vip17h 45m011:00 AMSantiago, RMTerminal San Borja4:45 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/24/2026 11:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 4:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 17h 45m
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FlixBus18h 35m012:15 PMSantiago, RMTerminal San Borja6:50 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/24/2026 12:15:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 6:50:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 18h 35m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/24/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/25/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/24/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Pluss Chile17h 55m07:45 AMSantiago, RMSur Bus Station1:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 3/24/2026 7:45:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 1:40:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 55m
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LAN Perú1h 59m05:11 AMSantiago de Chile AirportSantiago de Chile Airport7:10 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 5:11:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:10:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 1h 59m
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LATAM Brasil1h 59m05:11 AMSantiago de Chile AirportSantiago de Chile Airport7:10 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 5:11:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:10:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 59m
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JetSmart2h 4m05:27 AMSantiago de Chile AirportSantiago de Chile Airport7:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 5:27:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:31:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 2h 4m
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Sky Airline2h 1m05:59 AMSantiago de Chile AirportSantiago de Chile Airport8:00 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 5:59:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 8:00:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 2h 1m
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LAN Airlines1h 59m09:38 AMSantiago de Chile AirportSantiago de Chile Airport11:37 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 9:38:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 11:37:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 1h 59m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus18h 35m09:00 AMSantiago, RMTerminal San Borja3:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 9:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 3:35:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 18h 35m
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Nueva Andimar Vip18h 35m012:15 PMSantiago, RMTerminal San Borja6:50 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 12:15:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 6:50:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 18h 35m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/26/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Gentour16h 30m011:30 AMSantiago, RMTerminal San Borja4:00 AMAntofagastaMaipú0Premium EconomyA Bus from Gentour goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 11:30:00 AM to Maipú, Antofagasta (Chile) arriving at 3/26/2026 4:00:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 16h 30m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
Cheapest Buses Wednesday
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Sky Airline2h 1m09:53 AMSantiago de Chile AirportSantiago de Chile Airport11:54 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 9:53:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 11:54:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 2h 1m
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JetSmart2h 4m06:06 AMSantiago de Chile AirportSantiago de Chile Airport8:10 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 6:06:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 8:10:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 2h 4m
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LAN Perú1h 59m04:32 AMSantiago de Chile AirportSantiago de Chile Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 4:32:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 6:31:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 1h 59m
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LAN Airlines2h 0m012:50 PMSantiago de Chile AirportSantiago de Chile Airport2:50 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 12:50:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 2:50:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 2h 0m
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LATAM Brasil1h 59m04:32 AMSantiago de Chile AirportSantiago de Chile Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 4:32:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 6:31:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 1h 59m
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FlixBus18h 35m012:15 PMSantiago, RMTerminal San Borja6:50 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/26/2026 12:15:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 6:50:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 18h 35m
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Nueva Andimar Vip17h 45m011:00 AMSantiago, RMTerminal San Borja4:45 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/26/2026 11:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 4:45:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 17h 45m
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Pullman San Andres18h 40m05:00 PMSantiago, RMTerminal San Borja11:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/26/2026 5:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 11:40:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Cikbus Elité19h 0m07:30 AMSantiago, RMSur Bus Station2:30 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 3/26/2026 7:30:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 2:30:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 19h 0m
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Pluss Chile17h 55m07:45 AMSantiago, RMSur Bus Station1:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 3/26/2026 7:45:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 1:40:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 55m
Cheapest Flights Thursday
Cheapest Buses Thursday
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FlixBus18h 35m012:15 PMSantiago, RMTerminal San Borja6:50 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 12:15:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 6:50:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 18h 35m
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Nueva Andimar Vip17h 45m07:50 AMSantiago, RMTerminal San Borja1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 7:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 1:35:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 17h 45m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/28/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Pullman Bus18h 50m011:00 AMSantiago, RMTerminal San Borja5:50 AMAntofagastaCamus Bus Station0First ClassA Bus from Pullman Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 11:00:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 3/28/2026 5:50:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 18h 50m
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Sky Airline2h 1m06:44 AMSantiago de Chile AirportSantiago de Chile Airport8:45 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 6:44:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 8:45:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 2h 1m
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JetSmart2h 4m05:00 AMSantiago de Chile AirportSantiago de Chile Airport7:04 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 5:00:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 7:04:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 2h 4m
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LAN Perú1h 59m04:32 AMSantiago de Chile AirportSantiago de Chile Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 4:32:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 6:31:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 1h 59m
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LAN Airlines2h 0m03:02 PMSantiago de Chile AirportSantiago de Chile Airport5:02 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 3:02:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 5:02:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 2h 0m
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LATAM Brasil1h 59m04:32 AMSantiago de Chile AirportSantiago de Chile Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 4:32:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 6:31:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 59m
Cheapest Buses Friday
Cheapest Flights Friday
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Nueva Andimar Vip17h 45m07:50 AMSantiago, RMTerminal San Borja1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/28/2026 7:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:35:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 17h 45m
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FlixBus17h 45m07:50 AMSantiago, RMTerminal San Borja1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/28/2026 7:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:35:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 17h 45m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/28/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/29/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pluss Chile17h 55m07:45 AMSantiago, RMSur Bus Station1:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 3/28/2026 7:45:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:40:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 55m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/28/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
Cheapest Buses Saturday
What are the fastest trips from Santiago, RM to Antofagasta?
You can get to Antofagasta from Santiago, RM in just 1h 59m with a Flight from LAN Perú. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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LAN Perú4h 47m06:00 AMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 6:00:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 10:47:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 4h 47m
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LATAM Brasil20h 42m02:05 PMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 2:05:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:47:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 20h 42m
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Sky Airline24h 27m010:20 AMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 10:20:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:47:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 24h 27m
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JetSmart25h 59m08:48 AMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 8:48:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:47:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 25h 59m
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LAN Airlines26h 46m08:01 AMSantiago de Chile AirportSantiago de Chile Airport10:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/22/2026 8:01:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:47:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 26h 46m
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Gentour16h 30m06:30 PMSantiago, RMTerminal San Borja11:00 AMAntofagastaMaipú0Premium EconomyA Bus from Gentour goes from Terminal San Borja, Santiago, RM (Chile) at 3/22/2026 6:30:00 PM to Maipú, Antofagasta (Chile) arriving at 3/23/2026 11:00:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 16h 30m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/22/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/23/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/22/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Chile Bus19h 0m02:00 PMSantiago, RMTerminal San Borja9:00 AMAntofagastaCarlos Oviedo Cavada Bus Station0First ClassA Bus from Chile Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/22/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 9:00:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 19h 0m
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Cikbus Elité19h 5m01:30 PMSantiago, RMSur Bus Station8:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 3/22/2026 1:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 8:35:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 19h 5m
Fastest Flights Sunday
Fastest Buses Sunday
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LAN Perú1h 59m04:48 AMSantiago de Chile AirportSantiago de Chile Airport6:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 4:48:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 6:47:00 AM. 50 Economy ticket for $234 per person are available. Travel duration is 1h 59m
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LAN Airlines2h 0m08:52 PMSantiago de Chile AirportSantiago de Chile Airport10:52 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 8:52:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:52:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 2h 0m
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LATAM Brasil2h 0m08:52 PMSantiago de Chile AirportSantiago de Chile Airport10:52 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 8:52:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 10:52:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 2h 0m
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JetSmart2h 4m07:04 AMSantiago de Chile AirportSantiago de Chile Airport9:08 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 7:04:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 9:08:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 2h 4m
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Sky Airline10h 47m08:24 AMSantiago de Chile AirportSantiago de Chile Airport7:11 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/23/2026 8:24:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 7:11:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 10h 47m
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FlixBus18h 35m09:00 AMSantiago, RMTerminal San Borja3:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/23/2026 9:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 3:35:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 18h 35m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/23/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/24/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/23/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Cikbus Elité19h 0m07:30 AMSantiago, RMSur Bus Station2:30 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 3/23/2026 7:30:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 2:30:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 19h 0m
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Chile Bus19h 10m02:00 PMSantiago, RMTerminal San Borja9:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0First ClassA Bus from Chile Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/23/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 9:10:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 19h 10m
Fastest Flights Monday
Fastest Buses Monday
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LAN Perú1h 59m05:11 AMSantiago de Chile AirportSantiago de Chile Airport7:10 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 5:11:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:10:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 1h 59m
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LATAM Brasil1h 59m05:11 AMSantiago de Chile AirportSantiago de Chile Airport7:10 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 5:11:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:10:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 59m
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LAN Airlines1h 59m09:38 AMSantiago de Chile AirportSantiago de Chile Airport11:37 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 9:38:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 11:37:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 1h 59m
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Sky Airline2h 1m05:59 AMSantiago de Chile AirportSantiago de Chile Airport8:00 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 5:59:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 8:00:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 2h 1m
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JetSmart2h 4m05:27 AMSantiago de Chile AirportSantiago de Chile Airport7:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/24/2026 5:27:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:31:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 2h 4m
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Nueva Andimar Vip17h 45m011:00 AMSantiago, RMTerminal San Borja4:45 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/24/2026 11:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 4:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 17h 45m
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Pluss Chile17h 55m07:45 AMSantiago, RMSur Bus Station1:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 3/24/2026 7:45:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 1:40:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 55m
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FlixBus18h 35m012:15 PMSantiago, RMTerminal San Borja6:50 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/24/2026 12:15:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 6:50:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 18h 35m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/24/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/25/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/24/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Gentour16h 30m011:30 AMSantiago, RMTerminal San Borja4:00 AMAntofagastaMaipú0Premium EconomyA Bus from Gentour goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 11:30:00 AM to Maipú, Antofagasta (Chile) arriving at 3/26/2026 4:00:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 16h 30m
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FlixBus18h 35m09:00 AMSantiago, RMTerminal San Borja3:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 9:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 3:35:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 18h 35m
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Nueva Andimar Vip18h 35m012:15 PMSantiago, RMTerminal San Borja6:50 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 12:15:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 6:50:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 18h 35m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/26/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/25/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
Fastest Buses Wednesday
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LAN Perú1h 59m04:32 AMSantiago de Chile AirportSantiago de Chile Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 4:32:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 6:31:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 1h 59m
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LATAM Brasil1h 59m04:32 AMSantiago de Chile AirportSantiago de Chile Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 4:32:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 6:31:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 1h 59m
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LAN Airlines2h 0m012:50 PMSantiago de Chile AirportSantiago de Chile Airport2:50 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 12:50:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 2:50:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 2h 0m
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Sky Airline2h 1m09:53 AMSantiago de Chile AirportSantiago de Chile Airport11:54 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 9:53:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 11:54:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 2h 1m
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JetSmart2h 4m06:06 AMSantiago de Chile AirportSantiago de Chile Airport8:10 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/26/2026 6:06:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 8:10:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 2h 4m
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Nueva Andimar Vip17h 45m011:00 AMSantiago, RMTerminal San Borja4:45 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/26/2026 11:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 4:45:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 17h 45m
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Pluss Chile17h 55m07:45 AMSantiago, RMSur Bus Station1:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 3/26/2026 7:45:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 1:40:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 55m
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FlixBus18h 35m012:15 PMSantiago, RMTerminal San Borja6:50 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/26/2026 12:15:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 6:50:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 18h 35m
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Pullman San Andres18h 40m05:00 PMSantiago, RMTerminal San Borja11:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/26/2026 5:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 11:40:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Cikbus Elité19h 0m07:30 AMSantiago, RMSur Bus Station2:30 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 3/26/2026 7:30:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 2:30:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 19h 0m
Fastest Flights Thursday
Fastest Buses Thursday
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LAN Perú1h 59m04:32 AMSantiago de Chile AirportSantiago de Chile Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 4:32:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 6:31:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 1h 59m
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LATAM Brasil1h 59m04:32 AMSantiago de Chile AirportSantiago de Chile Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 4:32:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 6:31:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 59m
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LAN Airlines2h 0m03:02 PMSantiago de Chile AirportSantiago de Chile Airport5:02 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 3:02:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 5:02:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 2h 0m
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Sky Airline2h 1m06:44 AMSantiago de Chile AirportSantiago de Chile Airport8:45 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 6:44:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 8:45:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 2h 1m
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JetSmart2h 4m05:00 AMSantiago de Chile AirportSantiago de Chile Airport7:04 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 3/27/2026 5:00:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 7:04:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 2h 4m
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Nueva Andimar Vip17h 45m07:50 AMSantiago, RMTerminal San Borja1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 7:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 1:35:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 17h 45m
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FlixBus18h 35m012:15 PMSantiago, RMTerminal San Borja6:50 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 12:15:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 6:50:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 18h 35m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/28/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
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Pullman Bus18h 50m011:00 AMSantiago, RMTerminal San Borja5:50 AMAntofagastaCamus Bus Station0First ClassA Bus from Pullman Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/27/2026 11:00:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 3/28/2026 5:50:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 18h 50m
Fastest Flights Friday
Fastest Buses Friday
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Nueva Andimar Vip17h 45m07:50 AMSantiago, RMTerminal San Borja1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 3/28/2026 7:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:35:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 17h 45m
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FlixBus17h 45m07:50 AMSantiago, RMTerminal San Borja1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 3/28/2026 7:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:35:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 17h 45m
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Pluss Chile17h 55m07:45 AMSantiago, RMSur Bus Station1:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 3/28/2026 7:45:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:40:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 55m
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Cormar Bus18h 40m012:00 PMSantiago, RMTerminal San Borja6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 3/28/2026 12:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/29/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 40m
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Pullman San Andres18h 40m03:30 PMSantiago, RMTerminal San Borja10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 3/28/2026 3:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 10:10:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 40m
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from Santiago, RM to Antofagasta
What are the most popular stations in Santiago, RM and Antofagasta?
In Santiago, RM, you will usually depart from Terminal Alameda, Terminal San Borja or Sur Bus Station, while in Antofagasta you will be arriving at Maipú, Camus Bus Station or Carlos Oviedo Cavada Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Antofagasta from Santiago, RM? With 8 connections between 13 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Santiago, RM and Antofagasta, you can pay as low as $26 with a Flight from Sky Airline.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LAN Perú: you will get to Antofagasta in just 1h 59m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Santiago, RM and Antofagasta are Pullman San Andres, Cormar Bus and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Santiago, RM and Antofagasta is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Lo Prado or to La Negra, and look at flights from Santiago de Chile Airport, and landing at Andrés Sabella Gálvez, Antofagasta Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Santiago, RM to Antofagasta?
The most popular companies between Santiago, RM and Antofagasta, are Pullman San Andres, Cormar Bus and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Pullman San Andres, Cormar Bus, FlixBus and 6 more.
Airlines: JetSmart, LAN Airlines, LAN Perú and 2 more.
All you need to know when you travel from Santiago, RM to Antofagasta
Check all information on comfort and services on all modes of transports from Santiago, RM to Antofagasta. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Santiago, RM to Antofagasta
How can I reach Antofagasta from Santiago, RM?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Antofagasta from Santiago, RM.
How far is Antofagasta from Santiago, RM?
The distance between Santiago, RM and Antofagasta is 677.0 miles.
What is the most ecofriendly mode of transport between Santiago, RM and Antofagasta?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 29 kgs of CO2, a train 38 kgs, a car 185 kgs, and a flight 268 kgs.
What is the cheapest mode of transport from Santiago, RM to Antofagasta?
You can get to Antofagasta with just $26 by taking a Flight from Sky Airline.
What is the fastest way to get from Santiago, RM to Antofagasta?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Antofagasta in just 1h 59m with a Flight from LAN Perú.
More routes to Santiago, RM and to Antofagasta
Looking for more options? Here you can see the most popular routes to Santiago, RM and to Antofagasta. Simply click on a connection, and you’ll find all the details about the route!
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