How to get from Santiago, RM to Antofagasta

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What is the best way to travel from Santiago, RM to Antofagasta?

Looking for a trip? Compare all the available Buses and Flights for the journey to Antofagasta from Santiago, RM. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 14 available companies to find your perfect trip!
Flight is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
17h 10m
$27
$34
138
Flight
2h 1m
$21
$112
45

What is the cheapest way to reach Antofagasta from Santiago, RM?

You can get to Antofagasta with just $21 by taking a Flight from Sky Airline, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Friday
from $33
Saturday
from $31
Sunday
from $27
Monday
from $33
Tuesday
from $33
Wednesday
from $33
Thursday
from $21

    Cheapest Buses Friday

  • FlixBus
    18h 35m
    0
    12:15 PM
    Santiago, RM
    Terminal San Borja
    6:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Cikbus Elité
    17h 50m
    0
    9:30 AM
    Santiago, RM
    Terminal San Borja
    3:20 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    First Class
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    4:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Cormar Bus
    18h 10m
    0
    12:00 PM
    Santiago, RM
    Terminal San Borja
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $33
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $34
  • Cheapest Flights Friday

  • Sky Airline
    2h 7m
    0
    5:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:13 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $41
  • JetSmart
    2h 4m
    0
    5:54 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:58 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $50
  • JetSmart
    2h 4m
    0
    6:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $50
  • LAN Perú
    2h 1m
    0
    4:32 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:33 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $57
  • LAN Perú
    2h 1m
    0
    5:36 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:37 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $60

    Cheapest Buses Saturday

  • Cikbus Elité
    18h 45m
    0
    11:00 AM
    Santiago, RM
    Sur Bus Station
    5:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $31
  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $34
  • Pluss Chile
    17h 55m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Cheapest Flights Saturday

  • LAN Perú
    2h 1m
    0
    4:35 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:36 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $57
  • LAN Perú
    2h 1m
    0
    4:39 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:40 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $72
  • Sky Airline
    2h 7m
    0
    6:41 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:48 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $76
  • Sky Airline
    2h 3m
    0
    6:32 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:35 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $99
  • JetSmart
    27h 30m
    0
    5:25 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:55 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $186

    Cheapest Buses Sunday

  • Cikbus Elité
    19h 0m
    0
    7:30 AM
    Santiago, RM
    Terminal San Borja
    2:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    $27
  • Cormar Bus
    18h 10m
    0
    12:00 PM
    Santiago, RM
    Terminal San Borja
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $33
  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pluss Chile
    17h 55m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Cheapest Flights Sunday

  • Sky Airline
    2h 3m
    0
    8:25 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    10:28 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $63
  • LAN Perú
    11h 17m
    0
    10:29 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:46 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $80
  • LAN Airlines
    9h 39m
    0
    12:07 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:46 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $80
  • LAN Airlines
    7h 58m
    0
    1:48 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:46 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $80
  • LAN Perú
    2h 1m
    0
    4:39 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:40 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $81

    Cheapest Buses Monday

  • FlixBus
    18h 35m
    0
    12:15 PM
    Santiago, RM
    Terminal San Borja
    6:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    4:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Cikbus Elité
    19h 0m
    0
    7:30 AM
    Santiago, RM
    Sur Bus Station
    2:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $36
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $38
  • Cormar Bus
    17h 10m
    0
    9:50 AM
    Santiago, RM
    Terminal San Borja
    3:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cormar Bus
    First Class
    $43
  • Cheapest Flights Monday

  • LAN Perú
    2h 1m
    0
    4:32 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:33 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $107
  • JetSmart
    2h 4m
    0
    6:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $108
  • Sky Airline
    2h 7m
    0
    7:36 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:43 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $157
  • LAN Airlines
    2h 1m
    0
    7:29 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:30 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $225
  • Wamos Air
    20h 15m
    0
    8:15 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    4:30 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Wamos Air
    Economy
    from $726

    Cheapest Buses Tuesday

  • Cormar Bus
    18h 10m
    0
    12:00 PM
    Santiago, RM
    Terminal San Borja
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pluss Chile
    17h 20m
    0
    3:56 PM
    Santiago, RM
    Sur Bus Station
    9:16 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $38
  • Cheapest Flights Tuesday

  • JetSmart
    2h 4m
    0
    5:34 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:38 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $45
  • JetSmart
    2h 4m
    0
    6:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $45
  • Sky Airline
    2h 7m
    0
    6:21 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:28 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $45
  • LAN Airlines
    2h 1m
    0
    8:30 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    10:31 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $50
  • Sky Airline
    2h 7m
    0
    1:57 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    4:04 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $51

    Cheapest Buses Wednesday

  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pluss Chile
    17h 55m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Pullman San Andres
    18h 40m
    0
    2:00 PM
    Santiago, RM
    Terminal San Borja
    8:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $38
  • Cormar Bus
    17h 40m
    0
    6:55 PM
    Santiago, RM
    Terminal San Borja
    12:35 PM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    First Class
    $40
  • Cheapest Flights Wednesday

  • JetSmart
    2h 4m
    0
    4:46 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:50 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $46
  • Sky Airline
    2h 7m
    0
    3:39 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    5:46 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $51
  • LAN Airlines
    2h 1m
    0
    8:43 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    10:44 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $52
  • LAN Perú
    2h 1m
    0
    7:26 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:27 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $57
  • Wamos Air
    20h 15m
    0
    8:15 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    4:30 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Wamos Air
    Economy
    from $862

    Cheapest Flights Thursday

  • Sky Airline
    2h 7m
    0
    5:13 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:20 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $21
  • Sky Airline
    2h 7m
    0
    4:35 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:42 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $21
  • JetSmart
    2h 4m
    0
    6:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $33
  • JetSmart
    2h 4m
    0
    3:45 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    5:49 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $43
  • LAN Perú
    2h 1m
    0
    5:01 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:02 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $47
  • Cheapest Buses Thursday

  • Cikbus Elité
    18h 0m
    0
    11:00 PM
    Santiago, RM
    Terminal San Borja
    5:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    $27
  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pluss Chile
    17h 55m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $38

What are the fastest trips from Santiago, RM to Antofagasta?

You can get to Antofagasta from Santiago, RM in just 2h 1m with a Flight from LAN Perú. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Friday
from 2h 1m
Saturday
from 2h 1m
Sunday
from 2h 1m
Monday
from 2h 1m
Tuesday
from 2h 1m
Wednesday
from 2h 1m
Thursday
from 2h 1m

    Fastest Flights Friday

  • LAN Perú
    2h 1m
    0
    4:32 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:33 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $57
  • LAN Perú
    2h 1m
    0
    5:36 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:37 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $60
  • JetSmart
    2h 4m
    0
    5:54 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:58 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $50
  • JetSmart
    2h 4m
    0
    6:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $50
  • Sky Airline
    2h 7m
    0
    5:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:13 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $41
  • Fastest Buses Friday

  • Nueva Andimar Vip
    17h 45m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    4:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Cikbus Elité
    17h 50m
    0
    9:30 AM
    Santiago, RM
    Terminal San Borja
    3:20 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    First Class
    $33
  • Cormar Bus
    18h 10m
    0
    12:00 PM
    Santiago, RM
    Terminal San Borja
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $33
  • FlixBus
    18h 35m
    0
    12:15 PM
    Santiago, RM
    Terminal San Borja
    6:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $34

    Fastest Flights Saturday

  • LAN Perú
    2h 1m
    0
    4:35 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:36 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $57
  • LAN Perú
    2h 1m
    0
    4:39 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:40 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $72
  • Sky Airline
    2h 3m
    0
    6:32 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:35 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $99
  • Sky Airline
    2h 7m
    0
    6:41 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:48 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $76
  • JetSmart
    27h 30m
    0
    5:25 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:55 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $186
  • Fastest Buses Saturday

  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pluss Chile
    17h 55m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $34
  • Cikbus Elité
    18h 45m
    0
    11:00 AM
    Santiago, RM
    Sur Bus Station
    5:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $31

    Fastest Flights Sunday

  • LAN Perú
    2h 1m
    0
    4:39 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:40 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $81
  • Sky Airline
    2h 3m
    0
    8:25 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    10:28 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $63
  • LAN Airlines
    7h 58m
    0
    1:48 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:46 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $80
  • LAN Airlines
    9h 39m
    0
    12:07 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:46 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $80
  • LAN Perú
    11h 17m
    0
    10:29 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:46 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $80
  • Fastest Buses Sunday

  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pluss Chile
    17h 55m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Cormar Bus
    18h 10m
    0
    12:00 PM
    Santiago, RM
    Terminal San Borja
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $33
  • Cikbus Elité
    19h 0m
    0
    7:30 AM
    Santiago, RM
    Terminal San Borja
    2:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    $27

    Fastest Flights Monday

  • LAN Perú
    2h 1m
    0
    4:32 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:33 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $107
  • LAN Airlines
    2h 1m
    0
    7:29 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:30 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $225
  • JetSmart
    2h 4m
    0
    6:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $108
  • Sky Airline
    2h 7m
    0
    7:36 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:43 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $157
  • Wamos Air
    20h 15m
    0
    8:15 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    4:30 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Wamos Air
    Economy
    from $726
  • Fastest Buses Monday

  • Cormar Bus
    17h 10m
    0
    9:50 AM
    Santiago, RM
    Terminal San Borja
    3:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cormar Bus
    First Class
    $43
  • Nueva Andimar Vip
    17h 45m
    0
    11:00 AM
    Santiago, RM
    Terminal San Borja
    4:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    18h 35m
    0
    12:15 PM
    Santiago, RM
    Terminal San Borja
    6:50 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $38
  • Cikbus Elité
    19h 0m
    0
    7:30 AM
    Santiago, RM
    Sur Bus Station
    2:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $36

    Fastest Flights Tuesday

  • LAN Airlines
    2h 1m
    0
    8:30 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    10:31 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $50
  • JetSmart
    2h 4m
    0
    5:34 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:38 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $45
  • JetSmart
    2h 4m
    0
    6:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $45
  • Sky Airline
    2h 7m
    0
    6:21 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:28 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $45
  • Sky Airline
    2h 7m
    0
    1:57 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    4:04 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $51
  • Fastest Buses Tuesday

  • Pluss Chile
    17h 20m
    0
    3:56 PM
    Santiago, RM
    Sur Bus Station
    9:16 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Cormar Bus
    18h 10m
    0
    12:00 PM
    Santiago, RM
    Terminal San Borja
    6:10 AM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    Premium Economy
    $33
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $38

    Fastest Flights Wednesday

  • LAN Airlines
    2h 1m
    0
    8:43 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    10:44 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Airlines
    Economy
    from $52
  • LAN Perú
    2h 1m
    0
    7:26 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    9:27 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $57
  • JetSmart
    2h 4m
    0
    4:46 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:50 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $46
  • Sky Airline
    2h 7m
    0
    3:39 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    5:46 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $51
  • Wamos Air
    20h 15m
    0
    8:15 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    4:30 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Wamos Air
    Economy
    from $862
  • Fastest Buses Wednesday

  • Cormar Bus
    17h 40m
    0
    6:55 PM
    Santiago, RM
    Terminal San Borja
    12:35 PM
    Antofagasta
    Camus Bus Station
    0
    Cormar Bus
    First Class
    $40
  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pluss Chile
    17h 55m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Pullman San Andres
    18h 40m
    0
    2:00 PM
    Santiago, RM
    Terminal San Borja
    8:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $38

    Fastest Flights Thursday

  • LAN Perú
    2h 1m
    0
    5:01 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:02 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    LAN Perú
    Economy
    from $47
  • JetSmart
    2h 4m
    0
    6:06 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    8:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $33
  • JetSmart
    2h 4m
    0
    3:45 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    5:49 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    JetSmart
    Economy
    from $43
  • Sky Airline
    2h 7m
    0
    5:13 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    7:20 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $21
  • Sky Airline
    2h 7m
    0
    4:35 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    6:42 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    0
    Sky Airline
    Economy
    from $21
  • Fastest Buses Thursday

  • FlixBus
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    FlixBus
    Economy
    $33
  • Nueva Andimar Vip
    17h 45m
    0
    7:50 AM
    Santiago, RM
    Terminal San Borja
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Economy
    $33
  • Pluss Chile
    17h 55m
    0
    7:45 AM
    Santiago, RM
    Sur Bus Station
    1:40 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $35
  • Cikbus Elité
    18h 0m
    0
    11:00 PM
    Santiago, RM
    Terminal San Borja
    5:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    $27
  • Pullman San Andres
    18h 40m
    0
    3:30 PM
    Santiago, RM
    Terminal San Borja
    10:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $38
Here you will find all operators and timetables for a Bus from Santiago, RM to Antofagasta

What are the most popular stations in Santiago, RM and Antofagasta?

In Santiago, RM, you will usually depart from Terminal Alameda, Terminal San Borja or Sur Bus Station, while in Antofagasta you will be arriving at Carlos Oviedo Cavada Bus Station, Camus Bus Station or Maipú, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Antofagasta from Santiago, RM? With 10 connections between 14 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Santiago, RM and Antofagasta, you can pay as low as $21 with a Flight from Sky Airline.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LAN Perú: you will get to Antofagasta in just 2h 1m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Santiago, RM and Antofagasta are Sky Airline, JetSmart and LAN Perú, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Santiago, RM and Antofagasta is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Lo Prado or to La Negra, and look at flights from Santiago de Chile Airport, and landing at Andrés Sabella Gálvez, Antofagasta Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Santiago, RM to Antofagasta?

The most popular companies between Santiago, RM and Antofagasta, are Sky Airline, JetSmart and LAN Perú. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus, Nueva Andimar Vip, Pullman San Andres and 3 more.

Airlines: Sky Airline, JetSmart, LAN Perú and 2 more.

All you need to know when you travel from Santiago, RM to Antofagasta

Check all information on comfort and services on all modes of transports from Santiago, RM to Antofagasta. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Santiago, RM to Antofagasta

How can I reach Antofagasta from Santiago, RM?

Every day, there are on average 10 connections between Bus and Flight, with which you can get to Antofagasta from Santiago, RM.

How far is Antofagasta from Santiago, RM?

The distance between Santiago, RM and Antofagasta is 677.0 miles.

What is the most ecofriendly mode of transport between Santiago, RM and Antofagasta?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 29 kgs of CO2, a train 38 kgs, a car 185 kgs, and a flight 268 kgs.

What is the cheapest mode of transport from Santiago, RM to Antofagasta?

You can get to Antofagasta with just $21 by taking a Flight from Sky Airline.

What is the fastest way to get from Santiago, RM to Antofagasta?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Antofagasta in just 2h 1m with a Flight from LAN Perú.

More routes to Santiago, RM and to Antofagasta

Looking for more options? Here you can see the most popular routes to Santiago, RM and to Antofagasta. Simply click on a connection, and you’ll find all the details about the route!

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