Bus from Santiago, RM to Antofagasta from $29

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Compare all timetables for the bus from Santiago, RM to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to Antofagasta from various bus operators like Pluss Chile, Cikbus Elité or Pullman Bus for the next days.

today
$40
tomorrow
$33
Saturday
$40
Sunday
$33
Monday
$40
Tuesday
$33
Wednesday
$33

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pullman San Andres 18h 40m 10:00 PM Santiago, RM Terminal San Borja 4:40 PM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $40
Cikbus Elité 18h 45m 11:00 AM Santiago, RM Sur Bus Station 5:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $42
FlixBus 17h 45m 11:00 AM Santiago, RM Terminal San Borja 4:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $43
Cormar Bus 17h 40m 6:55 PM Santiago, RM Terminal San Borja 12:35 PM Antofagasta Camus Bus Station  First Class $44
Pluss Chile 18h 40m 9:30 AM Santiago, RM Sur Bus Station 4:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $45
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than $4? You can find the corresponding connections below.
    • FlixBus
      23h 25m
      0
      6:45 AM
      Santiago, RM
      Terminal San Borja
      12:00 PM
      Ovalle
      Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 5h 10m
    • kupos.cl
      13h 0m
      0
      5:10 PM
      Ovalle
      Bus Station
      6:10 AM
      Antofagasta
      Camus Bus Station
      0
      kupos.cl
      Premium Economy
      $28
    Travel time is 5h 45m longer, but you will save $4

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 35m 12:15 PM Santiago, RM Terminal San Borja 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $33
Cormar Bus 18h 10m 12:00 PM Santiago, RM Terminal San Borja 6:10 AM Antofagasta Camus Bus Station  Premium Economy $33
Pullman San Andres 18h 40m 7:00 AM Santiago, RM Terminal San Borja 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $40
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $43
Cikbus Elité 18h 45m 11:00 AM Santiago, RM Terminal San Borja 5:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Business $45

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $40
Nueva Andimar Vip 18h 35m 12:15 PM Santiago, RM Terminal San Borja 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $40
Cikbus Elité 17h 15m 4:45 PM Santiago, RM Sur Bus Station 10:00 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $42
FlixBus 17h 45m 11:00 AM Santiago, RM Terminal San Borja 4:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $43
Cormar Bus 17h 40m 3:20 PM Santiago, RM Terminal San Borja 9:00 AM Antofagasta Camus Bus Station  First Class $44
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than $4? You can find the corresponding connections below.
    • FlixBus
      23h 25m
      0
      6:45 AM
      Santiago, RM
      Terminal San Borja
      12:00 PM
      Ovalle
      Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 5h 10m
    • kupos.cl
      13h 0m
      0
      5:10 PM
      Ovalle
      Bus Station
      6:10 AM
      Antofagasta
      Camus Bus Station
      0
      kupos.cl
      Premium Economy
      $28
    Travel time is 6h 10m longer, but you will save $4

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 18h 10m 12:00 PM Santiago, RM Terminal San Borja 6:10 AM Antofagasta Camus Bus Station  Premium Economy $33
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $40
Cikbus Elité 17h 50m 9:00 AM Santiago, RM Sur Bus Station 2:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $42
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $43
Pluss Chile 17h 55m 7:45 AM Santiago, RM Sur Bus Station 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $45

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $40
Cikbus Elité 18h 45m 11:00 AM Santiago, RM Sur Bus Station 5:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $42
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $43
Cormar Bus 17h 10m 9:50 AM Santiago, RM Terminal San Borja 3:00 AM Antofagasta Carlos Oviedo Cavada Bus Station  First Class $44
Pluss Chile 17h 55m 7:45 AM Santiago, RM Sur Bus Station 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $45
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than $4? You can find the corresponding connections below.
    • FlixBus
      23h 25m
      0
      6:45 AM
      Santiago, RM
      Terminal San Borja
      12:00 PM
      Ovalle
      Bus Station
      0
      FlixBus
      Economy
      $8
      • Waiting Time 5h 10m
    • kupos.cl
      13h 0m
      0
      5:10 PM
      Ovalle
      Bus Station
      6:10 AM
      Antofagasta
      Camus Bus Station
      0
      kupos.cl
      Premium Economy
      $28
    Travel time is 6h 15m longer, but you will save $4

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 18h 10m 12:00 PM Santiago, RM Terminal San Borja 6:10 AM Antofagasta Camus Bus Station  Premium Economy $33
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $40
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $43
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Sur Bus Station 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $43
Pluss Chile 18h 40m 9:30 AM Santiago, RM Sur Bus Station 4:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $45

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 45m 11:00 AM Santiago, RM Terminal San Borja 4:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $33
Cikbus Elité 17h 50m 9:00 AM Santiago, RM Sur Bus Station 2:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $34
Pluss Chile 17h 55m 7:45 AM Santiago, RM Sur Bus Station 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $35
Cormar Bus 17h 40m 6:55 PM Santiago, RM Terminal San Borja 12:35 PM Antofagasta Camus Bus Station  First Class $40
Pullman San Andres 18h 40m 2:00 PM Santiago, RM Terminal San Borja 8:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $40

Best Price Offer: The price for the cheapest bus from Santiago, RM to Antofagasta is $29 on 1/7/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Santiago, RM and Antofagasta

See here how frequent the connections between Santiago, RM and Antofagasta are, during different times and days of the week.
Monday is the busiest day, with more than 129 daily buses from Santiago, RM to Antofagasta. Wednesday has instead the fewest connections, with only 58 daily coaches between Santiago, RM and Antofagasta.
The busiest time of the day is the Morning, with 228 buses from Santiago, RM to Antofagasta, while Evening sees the fewest connections between Santiago, RM and Antofagasta, with 197 offers.

Facts about the bus from Santiago, RM to Antofagasta

Compare all providers like Pluss Chile, Cikbus Elité and Pullman Bus that travel 92 times every day by bus from Santiago, RM to Antofagasta in one click! Book your bus ticket from Santiago, RM to Antofagasta starting from $29!

Cheapest Bus $29
Fastest Bus 16h 30m
Earliest Bus 9:30 AM
Latest Bus 11:30 PM
Daily Bus Routes 92 Ø
Distance 677.0 miles
Bus Companies Pluss Chile, Cikbus Elité, Pullman Bus, Pullman San Andres, FlixBus, Nueva Andimar Vip, Cormar Bus, Gentour and Ramos Cholele

Cheapest bus connections from Santiago, RM to Antofagasta

Every day, 92 buses from 9 bus companies leave Santiago, RM for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
$44
Friday 12/19
$40
Saturday 12/20
$42
Sunday 12/21
$37
Monday 12/22
$42
Tuesday 12/23
$33
Wednesday 12/24
$33
Thursday 12/25
$33
Friday 12/26
$33
Saturday 12/27
$40
Sunday 12/28
$33
Monday 12/29
$33
Tuesday 12/30
$33
Wednesday 12/31
$33
Thursday 01/01
$33
Friday 01/02
$33
Saturday 01/03
$33
Sunday 01/04
$43
Monday 01/05
$33
Tuesday 01/06
$29
Wednesday 01/07
$29
Thursday 01/08
$29
Friday 01/09
$31
Saturday 01/10

The cheapest time to travel from Santiago, RM to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to Antofagasta, for the next 30 days.
With a price starting from $29, Tuesday is the cheapest day for a bus from Santiago, RM to Antofagasta. Sunday instead is the most expensive day with prices starting from $33.
Afternoon is the cheapest day time for bus tickets from Santiago, RM to Antofagasta, with $33. Evening is the most expensive time of the day with prices starting from $34.

How to save money travelling from Santiago, RM to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago, RM to Antofagasta are also emptier.

Beloved bus companies from Santiago, RM to Antofagasta

These are the most booked bus companies between Santiago, RM to Antofagasta from our users.

Pullman San Andres from Santiago, RM to Antofagasta

Pullman San Andres

Here you will find the key facts about the Pullman San Andres bus route Santiago, RM to Antofagasta:

Cheapest Price $40
Fastest Bus 17h 55m
Earliest Bus 10:00 AM
Last Bus 11:30 PM
Daily Connections 22 Ø
Found on 12/18/2025

Cormar Bus from Santiago, RM to Antofagasta

Cormar Bus

Here you will find the key facts about the Cormar Bus bus route Santiago, RM to Antofagasta:

Cheapest Price $33
Fastest Bus 17h 10m
Earliest Bus 6:55 PM
Last Bus 6:55 PM
Daily Connections 3 Ø
Found on 12/18/2025

Latest reviews for bus companies on the route Santiago, RM - Antofagasta

Gentour
German Burgos, 9/1/2025
Bus con muy mal olor, sube gente tomando y fuman en los baños asientos incómodos. Super malo el servicio dejan a las personas fuera de los terminales en la calle. El bus no entra a los terminales. Pa ... Bus con muy mal olor, sube gente tomando y fuman en los baños asientos incómodos. Super malo el servicio dejan a las personas fuera de los terminales en la calle. El bus no entra a los terminales. Para nunca más con Gentour.

All bus stations and stops in Santiago, RM and Antofagasta

In the map below, you can see where to find all bus stations in Santiago, RM and Antofagasta.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago, RM to Antofagasta? Compare all modes of transports from Santiago, RM to Antofagasta.

Service and Comfort on the bus from Santiago, RM to Antofagasta

Want to know which seat classes are available on the buses from Santiago, RM to Antofagasta? Or which bus companies serve the route Santiago, RM to Antofagasta? Below you will find answers to your questions.

FAQs about the Santiago, RM to Antofagasta bus

How much does a Santiago, RM Antofagasta bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $29 and takes 18h 10m to reach Antofagasta. Compare offers to save money!

How much could I save by comparing buses from Santiago, RM to Antofagasta?

This route is offered by 9 companies with a range of ticket prices between $29 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Antofagasta.

On average, how many connections are available from Santiago, RM to Antofagasta each day?

Every day, the Santiago, RM to Antofagasta bus route is served by approximately 92 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago, RM to Antofagasta take?

The fastest bus from Santiago, RM to Antofagasta is offered by Gentour and takes 16h 30m. Bus tickets for this connection cost $83. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago, RM to Antofagasta?

The earliest bus arriving in Antofagasta from Santiago, RM starts at 9:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago, RM to Antofagasta?

The latest bus trip departing from Santiago, RM for Antofagasta starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago, RM Antofagasta route?

When traveling by bus from Santiago, RM to Antofagasta, passengers can travel with Pluss Chile, Cikbus Elité and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago, RM and Antofagasta?

You can check all the direct connections between Santiago, RM and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pluss Chile, Cikbus Elité and Pullman Bus.

What can I take with me on the Santiago, RM to Antofagasta bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago, RM Antofagasta bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to Antofagasta on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago, RM to Antofagasta?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 92 daily trips between Santiago, RM and Antofagasta. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago, RM to Antofagasta?

Prices and availability for 92 trips between Santiago, RM and Antofagasta change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago, RM to Antofagasta

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to Antofagasta

Here’s an overview of the most popular bus routes to Santiago, RM and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Maitencillo to Santiago, RM Buses from Maitencillo to Santiago, RM
Buses to Santiago, RM from Coquimbo Buses to Santiago, RM from Coquimbo
Bus Valparaíso (CL) to Santiago, RM Bus Valparaíso (CL) to Santiago, RM
Buses to Santiago, RM from Mendoza Buses to Santiago, RM from Mendoza
Bus Calama to Antofagasta Bus Calama to Antofagasta
Buses Iquique to Antofagasta Buses Iquique to Antofagasta
From Valparaíso (CL) to Antofagasta bus From Valparaíso (CL) to Antofagasta bus
From Arica, AP to Antofagasta bus From Arica, AP to Antofagasta bus
Popular Airport Shuttles to Santiago, RM and to Antofagasta
CheckMyBus › Buses in Chile › Bus to Santiago, RM › Bus to Antofagasta

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