Bus from Santiago, RM to Antofagasta from $31

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Compare all timetables for the bus from Santiago, RM to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to Antofagasta from various bus operators like Pluss Chile, Pullman San Andres or Pullman Bus for the next days.

today
$46
tomorrow
$46
Sunday
$45
Monday
$46
Tuesday
$46
Wednesday
$41
Thursday
$41

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 17h 40m 6:55 PM Santiago, RM Terminal San Borja 12:35 PM Antofagasta Camus Bus Station  First Class $46
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Nueva Andimar Vip 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $52
Pluss Chile 17h 55m 7:45 AM Santiago, RM Sur Bus Station 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $54
Pullman Bus 18h 50m 11:00 AM Santiago, RM Terminal San Borja 5:50 AM Antofagasta Camus Bus Station  First Class $56
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      8:30 AM
      Santiago, RM
      Terminal San Borja
      1:45 PM
      Ovalle
      Bus Station
      0
      FlixBus
      Economy
      $16
      • Waiting Time 4h 0m
    • Busbud
      13h 5m
      0
      5:45 PM
      Ovalle
      Bus Station
      6:50 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Busbud
      Economy
      $24
    Travel time is 4h 40m longer, but you will save $7

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 17h 40m 3:20 PM Santiago, RM Terminal San Borja 9:00 AM Antofagasta Camus Bus Station  First Class $46
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $52
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Sur Bus Station 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Pluss Chile 17h 55m 7:45 AM Santiago, RM Sur Bus Station 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $54
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      8:30 AM
      Santiago, RM
      Terminal San Borja
      1:45 PM
      Ovalle
      Bus Station
      0
      FlixBus
      Economy
      $16
      • Waiting Time 4h 0m
    • Busbud
      13h 5m
      0
      5:45 PM
      Ovalle
      Bus Station
      6:50 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Busbud
      Economy
      $24
    Travel time is 4h 40m longer, but you will save $7

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 17h 40m 6:00 PM Santiago, RM Terminal San Borja 11:40 AM Antofagasta Camus Bus Station  First Class $45
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Chile Bus 18h 30m 11:00 AM Santiago, RM Terminal San Borja 5:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  First Class $52
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $52
Pluss Chile 17h 55m 7:45 AM Santiago, RM Sur Bus Station 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $54
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than $6? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      8:30 AM
      Santiago, RM
      Terminal San Borja
      1:45 PM
      Ovalle
      Bus Station
      0
      FlixBus
      Economy
      $16
      • Waiting Time 4h 0m
    • Busbud
      13h 5m
      0
      5:45 PM
      Ovalle
      Bus Station
      6:50 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Busbud
      Economy
      $24
    Travel time is 4h 40m longer, but you will save $6

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 17h 50m 12:20 PM Santiago, RM Terminal San Borja 6:10 AM Antofagasta Camus Bus Station  First Class $46
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Terminal San Borja 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Business $50
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $52
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Pluss Chile 17h 55m 7:45 AM Santiago, RM Sur Bus Station 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $54
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      8:30 AM
      Santiago, RM
      Terminal San Borja
      1:45 PM
      Ovalle
      Bus Station
      0
      FlixBus
      Economy
      $16
      • Waiting Time 4h 0m
    • Busbud
      13h 5m
      0
      5:45 PM
      Ovalle
      Bus Station
      6:50 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Busbud
      Economy
      $24
    Travel time is 4h 35m longer, but you will save $7

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 18h 20m 10:55 PM Santiago, RM Terminal San Borja 5:15 PM Antofagasta Camus Bus Station  Premium Economy $46
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $52
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Sur Bus Station 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Pluss Chile 17h 55m 7:45 AM Santiago, RM Sur Bus Station 1:40 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $54
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      8:30 AM
      Santiago, RM
      Terminal San Borja
      1:45 PM
      Ovalle
      Bus Station
      0
      FlixBus
      Economy
      $16
      • Waiting Time 4h 0m
    • Busbud
      13h 5m
      0
      5:45 PM
      Ovalle
      Bus Station
      6:50 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Busbud
      Economy
      $24
    Travel time is 4h 35m longer, but you will save $7

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 45m 7:50 AM Santiago, RM Terminal San Borja 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $41
Cormar Bus 17h 40m 6:55 PM Santiago, RM Terminal San Borja 12:35 PM Antofagasta Camus Bus Station  First Class $43
Nueva Andimar Vip 18h 35m 12:15 PM Santiago, RM Terminal San Borja 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $44
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Sur Bus Station 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 35m 12:15 PM Santiago, RM Terminal San Borja 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $41
Cormar Bus 17h 40m 6:55 PM Santiago, RM Terminal San Borja 12:35 PM Antofagasta Camus Bus Station  First Class $46
FlixBus 20h 15m 10:35 AM Santiago, RM Los Libertadores Bus Stop 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $47
Pullman San Andres 18h 40m 3:30 PM Santiago, RM Terminal San Borja 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52
Cikbus Elité 19h 0m 7:30 AM Santiago, RM Sur Bus Station 2:30 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $52

Best Price Offer: The price for the cheapest bus from Santiago, RM to Antofagasta is $31 on 2/25/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Santiago, RM and Antofagasta

See here how frequent the connections between Santiago, RM and Antofagasta are, during different times and days of the week.
Sunday is the busiest day, with more than 148 daily buses from Santiago, RM to Antofagasta. Friday has instead the fewest connections, with only 83 daily coaches between Santiago, RM and Antofagasta.
The busiest time of the day is the Morning, with 298 buses from Santiago, RM to Antofagasta, while Evening sees the fewest connections between Santiago, RM and Antofagasta, with 246 offers.

Facts about the bus from Santiago, RM to Antofagasta

Compare all providers like Pluss Chile, Pullman San Andres and Pullman Bus that travel 118 times every day by bus from Santiago, RM to Antofagasta in one click! Book your bus ticket from Santiago, RM to Antofagasta starting from $31!

Cheapest Bus $31
Fastest Bus 16h 30m
Earliest Bus 6:50 AM
Latest Bus 11:30 PM
Daily Bus Routes 118 Ø
Distance 677.0 miles
Bus Companies Pluss Chile, Pullman San Andres, Pullman Bus, Cikbus Elité, FlixBus, Cormar Bus, Nueva Andimar Vip, Gentour and Chile Bus

Cheapest bus connections from Santiago, RM to Antofagasta

Every day, 118 buses from 9 bus companies leave Santiago, RM for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
$52
Saturday 02/07
$52
Sunday 02/08
$53
Monday 02/09
$52
Tuesday 02/10
$46
Wednesday 02/11
$48
Thursday 02/12
$41
Friday 02/13
$47
Saturday 02/14
$42
Sunday 02/15
$47
Monday 02/16
$46
Tuesday 02/17
$47
Wednesday 02/18
$37
Thursday 02/19
$37
Friday 02/20
$38
Saturday 02/21
$38
Sunday 02/22
$47
Monday 02/23
$36
Tuesday 02/24
$34
Wednesday 02/25
$31
Thursday 02/26
$33
Friday 02/27
$35
Saturday 02/28

The cheapest time to travel from Santiago, RM to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to Antofagasta, for the next 30 days.
With a price starting from $31, Tuesday is the cheapest day for a bus from Santiago, RM to Antofagasta. Sunday instead is the most expensive day with prices starting from $36.
Morning is the cheapest day time for bus tickets from Santiago, RM to Antofagasta, with $41. Evening is the most expensive time of the day with prices starting from $43.

How to save money travelling from Santiago, RM to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago, RM to Antofagasta are also emptier.

Beloved bus companies from Santiago, RM to Antofagasta

These are the most booked bus companies between Santiago, RM to Antofagasta from our users.

FlixBus from Santiago, RM to Antofagasta

FlixBus

Here you will find the key facts about the FlixBus bus route Santiago, RM to Antofagasta:

Cheapest Price $41
Fastest Bus 17h 45m
Earliest Bus 6:50 AM
Last Bus 1:15 PM
Daily Connections 10 Ø
Found on 2/6/2026

Pullman San Andres from Santiago, RM to Antofagasta

Pullman San Andres

Here you will find the key facts about the Pullman San Andres bus route Santiago, RM to Antofagasta:

Cheapest Price $52
Fastest Bus 17h 40m
Earliest Bus 7:00 AM
Last Bus 11:30 PM
Daily Connections 29 Ø
Found on 2/5/2026

Cikbus Elité from Santiago, RM to Antofagasta

Cikbus Elité

Here you will find the key facts about the Cikbus Elité bus route Santiago, RM to Antofagasta:

Cheapest Price $50
Fastest Bus 17h 15m
Earliest Bus 7:30 AM
Last Bus 11:00 PM
Daily Connections 26 Ø
Found on 2/5/2026

Latest reviews for bus companies on the route Santiago, RM - Antofagasta

Gentour
German Burgos, 9/1/2025
Bus con muy mal olor, sube gente tomando y fuman en los baños asientos incómodos. Super malo el servicio dejan a las personas fuera de los terminales en la calle. El bus no entra a los terminales. Pa ... Bus con muy mal olor, sube gente tomando y fuman en los baños asientos incómodos. Super malo el servicio dejan a las personas fuera de los terminales en la calle. El bus no entra a los terminales. Para nunca más con Gentour.

All bus stations and stops in Santiago, RM and Antofagasta

In the map below, you can see where to find all bus stations in Santiago, RM and Antofagasta.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago, RM to Antofagasta? Compare all modes of transports from Santiago, RM to Antofagasta.

Service and Comfort on the bus from Santiago, RM to Antofagasta

Want to know which seat classes are available on the buses from Santiago, RM to Antofagasta? Or which bus companies serve the route Santiago, RM to Antofagasta? Below you will find answers to your questions.

FAQs about the Santiago, RM to Antofagasta bus

How much does a Santiago, RM Antofagasta bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $31 and takes 17h 45m to reach Antofagasta. Compare offers to save money!

How much could I save by comparing buses from Santiago, RM to Antofagasta?

This route is offered by 9 companies with a range of ticket prices between $31 and $87. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Antofagasta.

On average, how many connections are available from Santiago, RM to Antofagasta each day?

Every day, the Santiago, RM to Antofagasta bus route is served by approximately 118 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago, RM to Antofagasta take?

The fastest bus from Santiago, RM to Antofagasta is offered by Gentour and takes 16h 30m. Bus tickets for this connection cost $87. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago, RM to Antofagasta?

The earliest bus arriving in Antofagasta from Santiago, RM starts at 6:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago, RM to Antofagasta?

The latest bus trip departing from Santiago, RM for Antofagasta starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago, RM Antofagasta route?

When traveling by bus from Santiago, RM to Antofagasta, passengers can travel with Pluss Chile, Pullman San Andres and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago, RM and Antofagasta?

You can check all the direct connections between Santiago, RM and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pluss Chile, Pullman San Andres and Pullman Bus.

What can I take with me on the Santiago, RM to Antofagasta bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago, RM Antofagasta bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to Antofagasta on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago, RM to Antofagasta?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 118 daily trips between Santiago, RM and Antofagasta. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago, RM to Antofagasta?

Prices and availability for 118 trips between Santiago, RM and Antofagasta change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago, RM to Antofagasta

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to Antofagasta

Here’s an overview of the most popular bus routes to Santiago, RM and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Villarrica (CL) to Santiago, RM Buses Villarrica (CL) to Santiago, RM
Bus to Santiago, RM from Placilla de Peñuelas Bus to Santiago, RM from Placilla de Peñuelas
Buses Osorno, LL to Santiago, RM Buses Osorno, LL to Santiago, RM
Buses from La Laguna de Zapallar to Santiago, RM Buses from La Laguna de Zapallar to Santiago, RM
Coquimbo to Antofagasta bus Coquimbo to Antofagasta bus
Bus to Antofagasta from Copiapó Bus to Antofagasta from Copiapó
Bus from Viña del Mar to Antofagasta Bus from Viña del Mar to Antofagasta
Bus from Salta to Antofagasta Bus from Salta to Antofagasta
Popular Airport Shuttles to Santiago, RM and to Antofagasta
CheckMyBus › Buses in Chile › Bus to Santiago, RM › Bus to Antofagasta

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