How to get from Antofagasta to Santiago, RM

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What is the best way to travel from Antofagasta to Santiago, RM?

Looking for a trip? Compare all the available Buses and Flights for the journey to Santiago, RM from Antofagasta. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 8 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
17h 1m
$24
$33
153
Flight
1h 52m
$29
$63
33

What is the cheapest way to reach Santiago, RM from Antofagasta?

You can get to Santiago, RM with just $24 by taking a Bus from Cikbus Elité, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Friday
from $24
Saturday
from $29
Sunday
from $30
Monday
from $30
Tuesday
from $31
Wednesday
from $24
Thursday
from $25

    Cheapest Buses Friday

  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    $24
  • Nueva Andimar Vip
    19h 0m
    0
    3:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Turbus
    18h 15m
    0
    4:15 AM
    Antofagasta
    Terminal Buses Camus
    10:30 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $32
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    Economy
    $35
  • Pullman San Andres
    17h 1m
    0
    11:59 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    5:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $35
  • Cheapest Flights Friday

  • LAN Airlines
    21h 18m
    0
    1:44 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:02 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $84
  • JetSmart
    28h 16m
    0
    8:42 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:58 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $90
  • LAN Perú
    1h 56m
    0
    11:00 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:56 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $94
  • JetSmart
    1h 52m
    0
    1:08 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    3:00 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $94
  • LAN Airlines
    1h 55m
    0
    4:51 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    6:46 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $94

    Cheapest Flights Saturday

  • Sky Airline
    3h 13m
    0
    5:43 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    8:56 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $29
  • Sky Airline
    1h 56m
    0
    8:56 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:52 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $29
  • JetSmart
    1h 52m
    0
    8:58 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:50 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $30
  • LAN Perú
    1h 55m
    0
    3:44 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    5:39 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $35
  • LAN Perú
    1h 55m
    0
    6:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    8:54 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $35
  • Cheapest Buses Saturday

  • Turbus
    18h 35m
    0
    4:30 PM
    Antofagasta
    Terminal Buses Camus
    11:05 AM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $31
  • Pullman Bus
    18h 30m
    0
    5:30 PM
    Antofagasta
    Terminal Buses Camus
    12:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $32
  • Cormar Bus
    18h 10m
    0
    9:30 PM
    Antofagasta
    Terminal Buses Camus
    3:40 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    $36
  • Pullman San Andres
    17h 30m
    0
    3:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    9:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    First Class
    $43

    Cheapest Buses Sunday

  • Cikbus Elité
    18h 50m
    0
    3:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:20 PM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Turbus
    17h 50m
    0
    12:20 AM
    Antofagasta
    Terminal Buses Camus
    6:10 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Cormar Bus
    18h 10m
    0
    9:30 PM
    Antofagasta
    Terminal Buses Camus
    3:40 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    $36

    Cheapest Buses Monday

  • Cikbus Elité
    18h 40m
    0
    1:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Turbus
    18h 15m
    0
    4:15 AM
    Antofagasta
    Terminal Buses Camus
    10:30 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $31
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Terminal Buses Camus
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37

    Cheapest Buses Tuesday

  • Turbus
    17h 10m
    0
    1:10 AM
    Antofagasta
    Terminal Buses Camus
    6:20 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $31
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pullman Bus
    19h 0m
    0
    3:30 PM
    Antofagasta
    Terminal Buses Camus
    10:30 AM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $32
  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    $33
  • Pullman San Andres
    17h 30m
    0
    3:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    9:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • Cheapest Flights Tuesday

  • LAN Perú
    1h 56m
    0
    8:49 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:45 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $36
  • LAN Perú
    1h 56m
    0
    9:46 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:42 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $36
  • JetSmart
    1h 52m
    0
    7:37 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:29 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $49
  • JetSmart
    1h 52m
    0
    12:08 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    2:00 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $50
  • LAN Airlines
    1h 56m
    0
    10:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:06 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $53

    Cheapest Buses Wednesday

  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    $24
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Terminal Buses Camus
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $32
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Pullman San Andres
    17h 1m
    0
    11:59 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    5:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • Cheapest Flights Wednesday

  • Sky Airline
    26h 6m
    0
    11:36 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:42 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $91
  • JetSmart
    28h 12m
    0
    9:30 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:42 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $95
  • JetSmart
    27h 53m
    0
    9:30 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:23 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $104
  • LAN Airlines
    24h 7m
    0
    3:14 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    3:21 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $104
  • LAN Perú
    1h 56m
    0
    9:46 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:42 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $105

    Cheapest Buses Thursday

  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    $25
  • Turbus
    18h 15m
    0
    4:15 AM
    Antofagasta
    Terminal Buses Camus
    10:30 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $27
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Terminal Buses Camus
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $32
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Premium Economy
    $34
  • Pullman San Andres
    17h 1m
    0
    11:59 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    5:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $35
  • Cheapest Flights Thursday

  • JetSmart
    1h 52m
    0
    11:37 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:29 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $43
  • Sky Airline
    1h 56m
    0
    11:27 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:23 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $47
  • JetSmart
    1h 52m
    0
    8:58 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:50 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $49
  • LAN Airlines
    1h 55m
    0
    10:39 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:34 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $49
  • LAN Airlines
    1h 55m
    0
    11:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:54 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $50

What are the fastest trips from Antofagasta to Santiago, RM?

You can get to Santiago, RM from Antofagasta in just 1h 52m with a Flight from JetSmart. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Friday
from 1h 52m
Saturday
from 1h 52m
Sunday
from 17h 50m
Monday
from 18h 15m
Tuesday
from 1h 52m
Wednesday
from 1h 56m
Thursday
from 1h 52m

    Fastest Flights Friday

  • JetSmart
    1h 52m
    0
    1:08 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    3:00 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $94
  • LAN Airlines
    1h 55m
    0
    4:51 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    6:46 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $94
  • LAN Perú
    1h 56m
    0
    11:00 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:56 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $94
  • LAN Airlines
    21h 18m
    0
    1:44 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:02 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $84
  • JetSmart
    28h 16m
    0
    8:42 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:58 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $90
  • Fastest Buses Friday

  • Pullman San Andres
    17h 1m
    0
    11:59 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    5:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $35
  • Turbus
    18h 15m
    0
    4:15 AM
    Antofagasta
    Terminal Buses Camus
    10:30 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $32
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    Economy
    $35
  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    $24
  • Nueva Andimar Vip
    19h 0m
    0
    3:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32

    Fastest Flights Saturday

  • JetSmart
    1h 52m
    0
    8:58 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:50 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $30
  • LAN Perú
    1h 55m
    0
    3:44 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    5:39 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $35
  • LAN Perú
    1h 55m
    0
    6:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    8:54 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $35
  • Sky Airline
    1h 56m
    0
    8:56 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:52 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $29
  • Sky Airline
    3h 13m
    0
    5:43 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    8:56 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $29
  • Fastest Buses Saturday

  • Pullman San Andres
    17h 30m
    0
    3:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    9:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • Cormar Bus
    18h 10m
    0
    9:30 PM
    Antofagasta
    Terminal Buses Camus
    3:40 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    $36
  • Pullman Bus
    18h 30m
    0
    5:30 PM
    Antofagasta
    Terminal Buses Camus
    12:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $32
  • Turbus
    18h 35m
    0
    4:30 PM
    Antofagasta
    Terminal Buses Camus
    11:05 AM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $31
  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    First Class
    $43

    Fastest Buses Sunday

  • Turbus
    17h 50m
    0
    12:20 AM
    Antofagasta
    Terminal Buses Camus
    6:10 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $32
  • Cormar Bus
    18h 10m
    0
    9:30 PM
    Antofagasta
    Terminal Buses Camus
    3:40 PM
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    $36
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Cikbus Elité
    18h 50m
    0
    3:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:20 PM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32

    Fastest Buses Monday

  • Turbus
    18h 15m
    0
    4:15 AM
    Antofagasta
    Terminal Buses Camus
    10:30 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $31
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Terminal Buses Camus
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $37
  • Cikbus Elité
    18h 40m
    0
    1:10 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32

    Fastest Flights Tuesday

  • JetSmart
    1h 52m
    0
    7:37 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    9:29 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $49
  • JetSmart
    1h 52m
    0
    12:08 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    2:00 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $50
  • LAN Perú
    1h 56m
    0
    8:49 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:45 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $36
  • LAN Perú
    1h 56m
    0
    9:46 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:42 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $36
  • LAN Airlines
    1h 56m
    0
    10:10 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:06 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $53
  • Fastest Buses Tuesday

  • Turbus
    17h 10m
    0
    1:10 AM
    Antofagasta
    Terminal Buses Camus
    6:20 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $31
  • Pullman San Andres
    17h 30m
    0
    3:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    9:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    $33
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32
  • Pullman Bus
    19h 0m
    0
    3:30 PM
    Antofagasta
    Terminal Buses Camus
    10:30 AM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $32

    Fastest Flights Wednesday

  • LAN Perú
    1h 56m
    0
    9:46 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:42 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from $105
  • LAN Airlines
    24h 7m
    0
    3:14 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    3:21 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $104
  • Sky Airline
    26h 6m
    0
    11:36 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:42 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $91
  • JetSmart
    27h 53m
    0
    9:30 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:23 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $104
  • JetSmart
    28h 12m
    0
    9:30 AM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:42 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $95
  • Fastest Buses Wednesday

  • Pullman San Andres
    17h 1m
    0
    11:59 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    5:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $37
  • Pluss Chile
    18h 20m
    0
    2:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    $34
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Terminal Buses Camus
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $32
  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    $24
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $32

    Fastest Flights Thursday

  • JetSmart
    1h 52m
    0
    11:37 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:29 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $43
  • JetSmart
    1h 52m
    0
    8:58 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:50 PM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from $49
  • LAN Airlines
    1h 55m
    0
    10:39 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:34 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $49
  • LAN Airlines
    1h 55m
    0
    11:59 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:54 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from $50
  • Sky Airline
    1h 56m
    0
    11:27 PM
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    1:23 AM
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from $47
  • Fastest Buses Thursday

  • Pullman San Andres
    17h 1m
    0
    11:59 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    5:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    $35
  • Turbus
    18h 15m
    0
    4:15 AM
    Antofagasta
    Terminal Buses Camus
    10:30 PM
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    $27
  • Pullman Bus
    18h 30m
    0
    12:30 AM
    Antofagasta
    Terminal Buses Camus
    7:00 PM
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    $32
  • Cikbus Elité
    18h 50m
    0
    1:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    7:50 PM
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    $25
  • Nueva Andimar Vip
    19h 0m
    0
    1:35 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    8:35 PM
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Premium Economy
    $34
Here you will find all operators and timetables for a Bus from Antofagasta to Santiago, RM

What are the most popular stations in Antofagasta and Santiago, RM?

In Antofagasta, you will usually depart from Carlos Oviedo Cavada Bus Station, Maipú or Terminal Tur Bus, while in Santiago, RM you will be arriving at Terminal San Borja, Los Libertadores Bus Stop or Terminal Pajaritos, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Santiago, RM from Antofagasta? With 8 connections between 8 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Antofagasta and Santiago, RM, you can pay as low as $24 with a Bus from Cikbus Elité.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from JetSmart: you will get to Santiago, RM in just 1h 52m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Antofagasta and Santiago, RM are JetSmart, Cikbus Elité and Nueva Andimar Vip, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Antofagasta and Santiago, RM is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Negra or to Lo Prado, and look at flights from Andrés Sabella Gálvez, Antofagasta Airport, and landing at Santiago de Chile Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Antofagasta to Santiago, RM?

The most popular companies between Antofagasta and Santiago, RM, are JetSmart, Cikbus Elité and Nueva Andimar Vip. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Cikbus Elité, Nueva Andimar Vip, Turbus and 4 more.

Airlines: JetSmart, LAN Airlines, LAN Perú and 1 more.

All you need to know when you travel from Antofagasta to Santiago, RM

Check all information on comfort and services on all modes of transports from Antofagasta to Santiago, RM. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Antofagasta to Santiago, RM

How can I reach Santiago, RM from Antofagasta?

Every day, there are on average 8 connections between Bus and Flight, with which you can get to Santiago, RM from Antofagasta.

How far is Santiago, RM from Antofagasta?

The distance between Antofagasta and Santiago, RM is 677.0 miles.

What is the most ecofriendly mode of transport between Antofagasta and Santiago, RM?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 29 kgs of CO2, a train 38 kgs, a car 185 kgs, and a flight 268 kgs.

What is the cheapest mode of transport from Antofagasta to Santiago, RM?

You can get to Santiago, RM with just $24 by taking a Bus from Cikbus Elité.

What is the fastest way to get from Antofagasta to Santiago, RM?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago, RM in just 1h 52m with a Flight from JetSmart.

More routes to Antofagasta and to Santiago, RM

Looking for more options? Here you can see the most popular routes to Antofagasta and to Santiago, RM. Simply click on a connection, and you’ll find all the details about the route!

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