Bus Antofagasta to Santiago, RM - Compare all Companies

Compare all timetables for the bus from Antofagasta to Santiago, RM

Here is a selection of the cheapest bus trips from the schedule from Antofagasta to Santiago, RM from various bus operators like Pullman San Andres, Pluss Chile or Pullman Bus for the next days.

today

$37

tomorrow

$37

Monday

$31

Tuesday

$33

Wednesday

$32

Thursday

$32

Friday

$32

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Pullman Bus	19h 15m	11:30 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	6:45 AM	Santiago, RM	Terminal San Borja	Business	$37	A Bus from Pullman Bus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/21/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/22/2026 6:45:00 AM. 50 Business ticket for $37 per person are available. Travel duration is 19h 15m
Pluss Chile	17h 30m	12:05 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Sur Bus Station	Premium Economy	$38	A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/21/2026 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/21/2026 5:35:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 30m
Pullman San Andres	18h 30m	4:30 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	11:00 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/21/2026 4:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/22/2026 11:00:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 30m
Chile Bus	19h 0m	10:30 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:30 AM	Santiago, RM	Terminal San Borja	First Class	$38	A Bus from Chile Bus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/21/2026 10:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/22/2026 5:30:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 19h 0m
Nueva Andimar Vip	19h 35m	10:00 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Terminal San Borja	Economy	$42	A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/21/2026 10:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/22/2026 5:35:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 19h 35m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Pullman Bus	20h 0m	1:00 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	9:00 PM	Santiago, RM	Terminal San Borja	Business	$37	A Bus from Pullman Bus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/22/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/22/2026 9:00:00 PM. 50 Business ticket for $37 per person are available. Travel duration is 20h 0m
Pluss Chile	17h 30m	12:05 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Sur Bus Station	Premium Economy	$38	A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/22/2026 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/22/2026 5:35:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 30m
Pullman San Andres	18h 30m	4:30 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	11:00 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/22/2026 4:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/23/2026 11:00:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 30m
Cormar Bus	18h 20m	2:00 PM	Antofagasta	Camus Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/22/2026 2:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/23/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 20m
Nueva Andimar Vip	19h 35m	10:00 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Terminal San Borja	Economy	$41	A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/22/2026 10:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/23/2026 5:35:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 19h 35m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Nueva Andimar Vip	19h 35m	10:00 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Terminal San Borja	Economy	$31	A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/23/2026 10:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/24/2026 5:35:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 19h 35m
FlixBus	19h 35m	6:30 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	2:05 PM	Santiago, RM	Terminal San Borja	Economy	$31	A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/23/2026 6:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/24/2026 2:05:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 19h 35m
Pullman Bus	19h 15m	11:30 AM	Antofagasta	Camus Bus Station	6:45 AM	Santiago, RM	Terminal San Borja	First Class	$33	A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/23/2026 11:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/24/2026 6:45:00 AM. 50 First Class ticket for $33 per person are available. Travel duration is 19h 15m
Pluss Chile	17h 30m	12:05 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Sur Bus Station	Premium Economy	$38	A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/23/2026 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/23/2026 5:35:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 30m
Cormar Bus	18h 20m	2:00 PM	Antofagasta	Camus Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/23/2026 2:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/24/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 20m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Pullman Bus	20h 0m	1:00 AM	Antofagasta	Camus Bus Station	9:00 PM	Santiago, RM	Terminal San Borja	First Class	$33	A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/24/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/24/2026 9:00:00 PM. 50 First Class ticket for $33 per person are available. Travel duration is 20h 0m
Nueva Andimar Vip	19h 35m	10:00 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Terminal San Borja	Economy	$34	A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 10:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/25/2026 5:35:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 19h 35m
FlixBus	19h 35m	6:30 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	2:05 PM	Santiago, RM	Terminal San Borja	Economy	$34	A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 6:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/25/2026 2:05:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 19h 35m
Cikbus Elité	18h 50m	3:10 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	10:00 PM	Santiago, RM	Sur Bus Station	Premium Economy	$36	A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 3:10:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/24/2026 10:00:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 50m
Pluss Chile	17h 30m	12:05 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Sur Bus Station	Premium Economy	$38	A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/24/2026 5:35:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 35m	10:00 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Terminal San Borja	Economy	$32	A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 10:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/26/2026 5:35:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 19h 35m
Pullman Bus	20h 0m	1:00 AM	Antofagasta	Camus Bus Station	9:00 PM	Santiago, RM	Terminal San Borja	First Class	$33	A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/25/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/25/2026 9:00:00 PM. 50 First Class ticket for $33 per person are available. Travel duration is 20h 0m
Nueva Andimar Vip	18h 0m	1:35 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	7:35 PM	Santiago, RM	Terminal San Borja	Economy	$34	A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 1:35:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/25/2026 7:35:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 18h 0m
Cikbus Elité	18h 50m	3:10 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	10:00 PM	Santiago, RM	Sur Bus Station	Premium Economy	$36	A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 3:10:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/25/2026 10:00:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 50m
Pluss Chile	17h 30m	12:05 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Sur Bus Station	Premium Economy	$38	A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/25/2026 5:35:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 30m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 35m	6:30 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	2:05 PM	Santiago, RM	Terminal San Borja	Economy	$32	A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 6:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/27/2026 2:05:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 19h 35m
Nueva Andimar Vip	18h 0m	1:35 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	7:35 PM	Santiago, RM	Terminal San Borja	Economy	$34	A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 1:35:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/26/2026 7:35:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 18h 0m
Cikbus Elité	18h 50m	3:10 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	10:00 PM	Santiago, RM	Sur Bus Station	Premium Economy	$36	A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 3:10:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/26/2026 10:00:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 50m
Pluss Chile	17h 30m	12:05 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Sur Bus Station	Premium Economy	$38	A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/26/2026 5:35:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 30m
Pullman Bus	20h 0m	1:00 AM	Antofagasta	Camus Bus Station	9:00 PM	Santiago, RM	Terminal San Borja	First Class	$38	A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/26/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/26/2026 9:00:00 PM. 50 First Class ticket for $38 per person are available. Travel duration is 20h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Nueva Andimar Vip	18h 0m	1:35 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	7:35 PM	Santiago, RM	Terminal San Borja	Economy	$32	A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 1:35:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/27/2026 7:35:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 18h 0m
Pluss Chile	17h 30m	12:05 AM	Antofagasta	Carlos Oviedo Cavada Bus Station	5:35 PM	Santiago, RM	Sur Bus Station	Premium Economy	$38	A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/27/2026 5:35:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 17h 30m
Pullman Bus	20h 0m	1:00 AM	Antofagasta	Camus Bus Station	9:00 PM	Santiago, RM	Terminal San Borja	First Class	$38	A Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/27/2026 1:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/27/2026 9:00:00 PM. 50 First Class ticket for $38 per person are available. Travel duration is 20h 0m
Pullman San Andres	18h 30m	11:30 PM	Antofagasta	Carlos Oviedo Cavada Bus Station	6:00 PM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 11:30:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 6:00:00 PM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 30m
Cormar Bus	18h 20m	2:00 PM	Antofagasta	Camus Bus Station	8:20 AM	Santiago, RM	Terminal San Borja	Premium Economy	$38	A Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/27/2026 2:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 3/28/2026 8:20:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 18h 20m

Did you know that if you travel from Antofagasta to Santiago, RM via La Serena, you can save more than $15? You can find the corresponding connections below.
- FlixBus
  
  18h 30m
  
  0
  
  6:30 PM
  
  Antofagasta
  Carlos Oviedo Cavada Bus Station
  
  6:40 AM
  
  La Serena
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 6:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 6:40:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 12h 10m
- Turbus
  
  6h 5m
  
  0
  
  6:55 AM
  
  La Serena
  Avda. Fco de Aguirre Station
  
  1:00 PM
  
  Santiago, RM
  Terminal Alameda
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 3/29/2026 6:55:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 3/29/2026 1:00:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 5m
Travel time is 1h 0m longer, but you will save $15

Best Price Offer: The price for the cheapest bus from Antofagasta to Santiago, RM is $29 on 4/9/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Antofagasta and Santiago, RM

See here how frequent the connections between Antofagasta and Santiago, RM are, during different times and days of the week.

Tuesday is the busiest day, with more than 154 daily buses from Antofagasta to Santiago, RM. Thursday has instead the fewest connections, with only 101 daily coaches between Antofagasta and Santiago, RM.

The busiest time of the day is the Evening, with 367 buses from Antofagasta to Santiago, RM, while Morning sees the fewest connections between Antofagasta and Santiago, RM, with 88 offers.

Facts about the bus from Antofagasta to Santiago, RM

Compare all providers like Pullman San Andres, Pluss Chile and Pullman Bus that travel 118 times every day by bus from Antofagasta to Santiago, RM in one click! Book your bus ticket from Antofagasta to Santiago, RM starting from $29!

Cheapest Bus	$29
Fastest Bus	17h 5m
Earliest Bus	12:05 AM
Latest Bus	11:59 PM
Daily Bus Routes	118 Ø
Distance	677.0 miles
Bus Companies	Pullman San Andres, Pluss Chile, Pullman Bus, Cikbus Elité, Cormar Bus, FlixBus, Nueva Andimar Vip, Chile Bus and Roma Buses

Cheapest bus connections from Antofagasta to Santiago, RM

Every day, 118 buses from 9 bus companies leave Antofagasta for Santiago, RM: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/15

Monday 03/16

Tuesday 03/17

Wednesday 03/18

Thursday 03/19

Friday 03/20

Saturday 03/21

$38

Sunday 03/22

$38

Monday 03/23

$38

Tuesday 03/24

$33

Wednesday 03/25

$32

Thursday 03/26

$34

Friday 03/27

$32

Saturday 03/28

$29

Sunday 03/29

$31

Monday 03/30

$33

Tuesday 03/31

$38

Wednesday 04/01

$38

Thursday 04/02

$43

Friday 04/03

$56

Saturday 04/04

$33

Sunday 04/05

$38

Monday 04/06

$32

Tuesday 04/07

$30

Wednesday 04/08

$30

Thursday 04/09

$29

Friday 04/10

$29

Saturday 04/11

The cheapest time to travel from Antofagasta to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to Santiago, RM, for the next 30 days.

With a price starting from $29, Sunday is the cheapest day for a bus from Antofagasta to Santiago, RM. Sunday instead is the most expensive day with prices starting from $29.

Night is the cheapest day time for bus tickets from Antofagasta to Santiago, RM, with $29. Morning is the most expensive time of the day with prices starting from $33.

How to save money travelling from Antofagasta to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Antofagasta to Santiago, RM are also emptier.

Beloved bus companies from Antofagasta to Santiago, RM

These are the most booked bus companies between Antofagasta to Santiago, RM from our users.

Pluss Chile from Antofagasta to Santiago, RM

Here you will find the key facts about the Pluss Chile bus route Antofagasta to Santiago, RM:

Cheapest Price	$38
Fastest Bus	17h 30m
Earliest Bus	12:05 AM
Last Bus	10:50 PM
Daily Connections	29 Ø
Found on	3/21/2026

Pullman San Andres from Antofagasta to Santiago, RM

Here you will find the key facts about the Pullman San Andres bus route Antofagasta to Santiago, RM:

Cheapest Price	$38
Fastest Bus	17h 20m
Earliest Bus	12:30 AM
Last Bus	11:30 PM
Daily Connections	36 Ø
Found on	3/21/2026

Pullman Bus from Antofagasta to Santiago, RM

Here you will find the key facts about the Pullman Bus bus route Antofagasta to Santiago, RM:

Cheapest Price	$33
Fastest Bus	17h 30m
Earliest Bus	1:00 AM
Last Bus	11:30 PM
Daily Connections	17 Ø
Found on	3/21/2026

All bus stations and stops in Antofagasta and Santiago, RM

In the map below, you can see where to find all bus stations in Antofagasta and Santiago, RM.

Camus Bus Station

Carlos Oviedo Cavada Bus Station

Avenida Pedro Aguirre Cerda 5750

Terminal Tur Bus

Almte. Juan José Latorre 2751

Pedro Aguirre Cerda esq. Nicolas Tirado Bus Stop

La Portada

Sur Bus Station

Av Libertador Bernardo O'Higgins 3850

Terminal San Borja

San Francisco de Borja 198-180

Terminal Alameda

Av Libertador Bernardo O'Higgins 3750

Terminal Pajaritos

Av. Gral. Óscar Bonilla 5935-5939

Los Héroes Station

Tucapel Jiménez 22

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Antofagasta to Santiago, RM? Compare all modes of transports from Antofagasta to Santiago, RM.

Service and Comfort on the bus from Antofagasta to Santiago, RM

Want to know which seat classes are available on the buses from Antofagasta to Santiago, RM? Or which bus companies serve the route Antofagasta to Santiago, RM? Below you will find answers to your questions.

FAQs about the Antofagasta to Santiago, RM bus

How much does a Antofagasta Santiago, RM bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $29 and takes 19h 35m to reach Santiago, RM. Compare offers to save money!

How much could I save by comparing buses from Antofagasta to Santiago, RM?

This route is offered by 9 companies with a range of ticket prices between $29 and $70. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago, RM.

On average, how many connections are available from Antofagasta to Santiago, RM each day?

Every day, the Antofagasta to Santiago, RM bus route is served by approximately 118 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Antofagasta to Santiago, RM take?

The fastest bus from Antofagasta to Santiago, RM is offered by Cikbus Elité and takes 17h 5m. Bus tickets for this connection cost $44. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Antofagasta to Santiago, RM?

The earliest bus arriving in Santiago, RM from Antofagasta starts at 12:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Antofagasta to Santiago, RM?

The latest bus trip departing from Antofagasta for Santiago, RM starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Antofagasta Santiago, RM route?

When traveling by bus from Antofagasta to Santiago, RM, passengers can travel with Pullman San Andres, Pluss Chile and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Antofagasta and Santiago, RM?

You can check all the direct connections between Antofagasta and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman San Andres, Pluss Chile and Pullman Bus.

What can I take with me on the Antofagasta to Santiago, RM bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Antofagasta Santiago, RM bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to Santiago, RM on your planned travel date.

How does CheckMyBus find the best bus deals from Antofagasta to Santiago, RM?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 118 daily trips between Antofagasta and Santiago, RM. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Antofagasta to Santiago, RM?

Prices and availability for 118 trips between Antofagasta and Santiago, RM change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Antofagasta to Santiago, RM

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to Santiago, RM

Here’s an overview of the most popular bus routes to Antofagasta and to Santiago, RM. Simply click on the connection of your choice, and you will find all the details about your bus route!