Which bus from Antofagasta to Santiago, RM is the cheapest?

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Compare all timetables for the bus from Antofagasta to Santiago, RM

Here is a selection of the cheapest bus trips from the schedule from Antofagasta to Santiago, RM from various bus operators like Pluss Chile, Pullman San Andres or Cikbus Elité for the next days.

today
$43
tomorrow
$45
Thursday
$38
Friday
$45
Saturday
$40
Sunday
$40
Monday
$39

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 18h 10m 2:10 PM Antofagasta Camus Bus Station 8:20 AM Santiago, RM Terminal San Borja  Premium Economy $43
Buses Norte Azul 18h 5m 8:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 2:05 PM Santiago, RM Terminal San Borja  Premium Economy $44
Pullman San Andres 18h 30m 3:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM Santiago, RM Terminal San Borja  Premium Economy $46
Pluss Chile 18h 20m 10:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 4:50 AM Santiago, RM Sur Bus Station  Premium Economy $48
Transportes San Antonio 18h 30m 4:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 11:00 AM Santiago, RM Terminal San Borja  Premium Economy $50

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 17h 50m 8:20 PM Antofagasta Camus Bus Station 2:10 PM Santiago, RM Terminal San Borja  First Class $45
Pullman San Andres 18h 30m 3:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM Santiago, RM Terminal San Borja  Premium Economy $46
Cikbus Elité 21h 0m 8:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:30 AM Santiago, RM Sur Bus Station  Premium Economy $47
Pluss Chile 17h 30m 12:05 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:35 PM Santiago, RM Sur Bus Station  Premium Economy $48
FlixBus 18h 0m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 7:35 PM Santiago, RM Terminal San Borja  Economy $51

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pullman Bus 18h 30m 12:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 7:00 PM Santiago, RM Terminal San Borja  Business $38
Cormar Bus 18h 10m 2:10 PM Antofagasta Camus Bus Station 8:20 AM Santiago, RM Terminal San Borja  Premium Economy $43
Pullman San Andres 18h 30m 11:00 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:30 AM Santiago, RM Terminal San Borja  Premium Economy $44
Chile Bus 19h 1m 11:59 PM Antofagasta Carlos Oviedo Cavada Bus Station 7:00 PM Santiago, RM Terminal San Borja  Premium Economy $46
Nueva Andimar Vip 18h 0m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 9:35 PM Santiago, RM Terminal San Borja  Economy $46

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 17h 50m 8:20 PM Antofagasta Camus Bus Station 2:10 PM Santiago, RM Terminal San Borja  First Class $45
Pullman San Andres 18h 30m 3:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM Santiago, RM Terminal San Borja  Premium Economy $46
Nueva Andimar Vip 18h 0m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 9:35 PM Santiago, RM Terminal San Borja  Economy $46
Cikbus Elité 21h 0m 8:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:30 AM Santiago, RM Sur Bus Station  Premium Economy $47
Pluss Chile 17h 30m 12:05 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:35 PM Santiago, RM Sur Bus Station  Premium Economy $48

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 35m 10:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 5:35 PM Santiago, RM Terminal San Borja  Economy $40
Nueva Andimar Vip 18h 0m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 9:35 PM Santiago, RM Terminal San Borja  Economy $41
Cormar Bus 17h 50m 8:20 PM Antofagasta Camus Bus Station 2:10 PM Santiago, RM Terminal San Borja  First Class $45
Pullman San Andres 18h 30m 3:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM Santiago, RM Terminal San Borja  Premium Economy $46
Cikbus Elité 21h 0m 8:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:30 AM Santiago, RM Sur Bus Station  Premium Economy $47

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 35m 10:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 5:35 PM Santiago, RM Terminal San Borja  Economy $40
Cormar Bus 17h 50m 8:20 PM Antofagasta Camus Bus Station 2:10 PM Santiago, RM Terminal San Borja  First Class $45
Pullman San Andres 18h 30m 3:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM Santiago, RM Terminal San Borja  Premium Economy $46
Cikbus Elité 21h 0m 8:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:30 AM Santiago, RM Sur Bus Station  Premium Economy $47
Pluss Chile 17h 30m 12:05 AM Antofagasta Carlos Oviedo Cavada Bus Station 5:35 PM Santiago, RM Sur Bus Station  Premium Economy $48

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 19h 35m 6:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 2:05 PM Santiago, RM Terminal San Borja  Economy $39
FlixBus 18h 0m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 9:35 PM Santiago, RM Terminal San Borja  Economy $40
Pullman San Andres 18h 30m 11:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 6:00 PM Santiago, RM Terminal San Borja  Premium Economy $42
Cormar Bus 17h 10m 9:05 PM Antofagasta Camus Bus Station 2:15 PM Santiago, RM Terminal San Borja  First Class $45
Cikbus Elité 18h 50m 3:10 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 PM Santiago, RM Sur Bus Station  Premium Economy $47

Best Price Offer: The price for the cheapest bus from Antofagasta to Santiago, RM is $33 on 2/24/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Antofagasta and Santiago, RM

See here how frequent the connections between Antofagasta and Santiago, RM are, during different times and days of the week.
Monday is the busiest day, with more than 133 daily buses from Antofagasta to Santiago, RM. Tuesday has instead the fewest connections, with only 46 daily coaches between Antofagasta and Santiago, RM.
The busiest time of the day is the Evening, with 309 buses from Antofagasta to Santiago, RM, while Morning sees the fewest connections between Antofagasta and Santiago, RM, with 65 offers.

Facts about the bus from Antofagasta to Santiago, RM

Compare all providers like Pluss Chile, Pullman San Andres and Cikbus Elité that travel 95 times every day by bus from Antofagasta to Santiago, RM in one click! Book your bus ticket from Antofagasta to Santiago, RM starting from $33!

Cheapest Bus $33
Fastest Bus 17h 5m
Earliest Bus 10:30 AM
Latest Bus 11:59 PM
Daily Bus Routes 95 Ø
Distance 677.0 miles
Bus Companies Pluss Chile, Pullman San Andres, Cikbus Elité, Pullman Bus, FlixBus, Nueva Andimar Vip, Cormar Bus, Chile Bus, Transportes San Antonio and Buses Norte Azul

Cheapest bus connections from Antofagasta to Santiago, RM

Every day, 95 buses from 10 bus companies leave Antofagasta for Santiago, RM: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/03/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
$44
Wednesday 02/04
$47
Thursday 02/05
$43
Friday 02/06
$43
Saturday 02/07
$40
Sunday 02/08
$40
Monday 02/09
$43
Tuesday 02/10
$48
Wednesday 02/11
$48
Thursday 02/12
$48
Friday 02/13
$37
Saturday 02/14
$43
Sunday 02/15
$41
Monday 02/16
$36
Tuesday 02/17
$34
Wednesday 02/18
$34
Thursday 02/19
$36
Friday 02/20
$37
Saturday 02/21
$38
Sunday 02/22
$38
Monday 02/23
$43
Tuesday 02/24
$33
Wednesday 02/25
$35
Thursday 02/26
$35
Friday 02/27
$43
Saturday 02/28

The cheapest time to travel from Antofagasta to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to Santiago, RM, for the next 30 days.
With a price starting from $33, Tuesday is the cheapest day for a bus from Antofagasta to Santiago, RM. Sunday instead is the most expensive day with prices starting from $38.
Night is the cheapest day time for bus tickets from Antofagasta to Santiago, RM, with $33. Morning is the most expensive time of the day with prices starting from $44.

How to save money travelling from Antofagasta to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Antofagasta to Santiago, RM are also emptier.

Beloved bus companies from Antofagasta to Santiago, RM

These are the most booked bus companies between Antofagasta to Santiago, RM from our users.

All bus stations and stops in Antofagasta and Santiago, RM

In the map below, you can see where to find all bus stations in Antofagasta and Santiago, RM.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Antofagasta to Santiago, RM? Compare all modes of transports from Antofagasta to Santiago, RM.

Service and Comfort on the bus from Antofagasta to Santiago, RM

Want to know which seat classes are available on the buses from Antofagasta to Santiago, RM? Or which bus companies serve the route Antofagasta to Santiago, RM? Below you will find answers to your questions.

FAQs about the Antofagasta to Santiago, RM bus

How much does a Antofagasta Santiago, RM bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $33 and takes 18h 30m to reach Santiago, RM. Compare offers to save money!

How much could I save by comparing buses from Antofagasta to Santiago, RM?

This route is offered by 10 companies with a range of ticket prices between $33 and $76. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago, RM.

On average, how many connections are available from Antofagasta to Santiago, RM each day?

Every day, the Antofagasta to Santiago, RM bus route is served by approximately 95 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Antofagasta to Santiago, RM take?

The fastest bus from Antofagasta to Santiago, RM is offered by Cikbus Elité and takes 17h 5m. Bus tickets for this connection cost $59. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Antofagasta to Santiago, RM?

The earliest bus arriving in Santiago, RM from Antofagasta starts at 10:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Antofagasta to Santiago, RM?

The latest bus trip departing from Antofagasta for Santiago, RM starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Antofagasta Santiago, RM route?

When traveling by bus from Antofagasta to Santiago, RM, passengers can travel with Pluss Chile, Pullman San Andres and Cikbus Elité. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Antofagasta and Santiago, RM?

You can check all the direct connections between Antofagasta and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pluss Chile, Pullman San Andres and Cikbus Elité.

What can I take with me on the Antofagasta to Santiago, RM bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Antofagasta Santiago, RM bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to Santiago, RM on your planned travel date.

How does CheckMyBus find the best bus deals from Antofagasta to Santiago, RM?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 95 daily trips between Antofagasta and Santiago, RM. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Antofagasta to Santiago, RM?

Prices and availability for 95 trips between Antofagasta and Santiago, RM change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Antofagasta to Santiago, RM

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to Santiago, RM

Here’s an overview of the most popular bus routes to Antofagasta and to Santiago, RM. Simply click on the connection of your choice, and you will find all the details about your bus route!

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