What is the best way to travel from Chicago to Santiago de Queretaro?
Looking for a trip? Compare all the available Buses and Flights for the journey to Santiago de Queretaro from Chicago. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Santiago de Queretaro from Chicago?
You can get to Santiago de Queretaro with just $222 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US57h 0m09:40 AMChicagoDowntown Bus Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/15/2025 9:40:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/17/2025 6:40:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 57h 0m
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Greyhound US56h 40m010:00 AMChicagoUnion Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/15/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/17/2025 6:40:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 56h 40m
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Greyhound US45h 30m010:30 PMChicagoDowntown Bus Station8:00 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/15/2025 10:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/17/2025 8:00:00 PM. 50 Economy ticket for $249 per person are available. Travel duration is 45h 30m
Cheapest Buses Monday
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FlixBus56h 55m09:45 AMChicagoDowntown Bus Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/16/2025 9:45:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/18/2025 6:40:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 56h 55m
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Greyhound US56h 40m010:00 AMChicagoUnion Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/16/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/18/2025 6:40:00 PM. 50 Economy ticket for $248 per person are available. Travel duration is 56h 40m
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Greyhound US51h 50m010:30 PMChicagoDowntown Bus Station2:20 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/16/2025 10:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 2:20:00 AM. 50 Economy ticket for $288 per person are available. Travel duration is 51h 50m
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Greyhound US58h 20m011:10 PMChicagoUnion Station9:30 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/16/2025 11:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 9:30:00 AM. 50 Economy ticket for $292 per person are available. Travel duration is 58h 20m
Cheapest Buses Tuesday
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Greyhound US56h 40m010:00 AMChicagoCanal & Van Buren6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/18/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 6:40:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 56h 40m
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Greyhound US56h 40m010:00 AMChicagoUnion Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/18/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 6:40:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 56h 40m
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FlixBus47h 20m010:10 AMChicago95th Red Line Station9:30 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/18/2025 10:10:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 9:30:00 AM. 50 Economy ticket for $251 per person are available. Travel duration is 47h 20m
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Greyhound US59h 30m010:00 PMChicagoCanal & Van Buren9:30 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/18/2025 10:00:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/21/2025 9:30:00 AM. 50 Economy ticket for $253 per person are available. Travel duration is 59h 30m
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FlixBus47h 45m09:45 AMChicagoDowntown Bus Station9:30 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/18/2025 9:45:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 9:30:00 AM. 50 Economy ticket for $254 per person are available. Travel duration is 47h 45m
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Spirit Airlines34h 12m06:05 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:17 PMQuerétaro AirportQuerétaro Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 6:05:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/19/2025 4:17:00 PM. 50 Economy ticket for $332 per person are available. Travel duration is 34h 12m
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Frontier Airlines25h 50m07:00 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center8:50 AMQuerétaro AirportQuerétaro Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 7:00:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/19/2025 8:50:00 AM. 50 Economy ticket for $375 per person are available. Travel duration is 25h 50m
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Volaris4h 13m06:00 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:13 AMQuerétaro AirportQuerétaro Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 6:00:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/18/2025 10:13:00 AM. 50 Economy ticket for $427 per person are available. Travel duration is 4h 13m
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United Airlines15h 10m05:49 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center8:59 PMQuerétaro AirportQuerétaro Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 5:49:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/18/2025 8:59:00 PM. 50 Economy ticket for $647 per person are available. Travel duration is 15h 10m
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Delta Air Lines11h 27m06:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:12 PMQuerétaro AirportQuerétaro Airport0EconomyA Flight from Delta Air Lines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 6:45:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/18/2025 6:12:00 PM. 50 Economy ticket for $719 per person are available. Travel duration is 11h 27m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Chicago to Santiago de Queretaro?
You can get to Santiago de Queretaro from Chicago in just 4h 13m with a Flight from Volaris. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Greyhound US45h 30m010:30 PMChicagoDowntown Bus Station8:00 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/15/2025 10:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/17/2025 8:00:00 PM. 50 Economy ticket for $249 per person are available. Travel duration is 45h 30m
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Greyhound US56h 40m010:00 AMChicagoUnion Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/15/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/17/2025 6:40:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 56h 40m
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Greyhound US57h 0m09:40 AMChicagoDowntown Bus Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/15/2025 9:40:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/17/2025 6:40:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 57h 0m
Fastest Buses Monday
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Greyhound US51h 50m010:30 PMChicagoDowntown Bus Station2:20 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/16/2025 10:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 2:20:00 AM. 50 Economy ticket for $288 per person are available. Travel duration is 51h 50m
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Greyhound US56h 40m010:00 AMChicagoUnion Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/16/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/18/2025 6:40:00 PM. 50 Economy ticket for $248 per person are available. Travel duration is 56h 40m
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FlixBus56h 55m09:45 AMChicagoDowntown Bus Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/16/2025 9:45:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/18/2025 6:40:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 56h 55m
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Greyhound US58h 20m011:10 PMChicagoUnion Station9:30 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/16/2025 11:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 9:30:00 AM. 50 Economy ticket for $292 per person are available. Travel duration is 58h 20m
Fastest Buses Tuesday
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Volaris4h 13m06:00 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:13 AMQuerétaro AirportQuerétaro Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 6:00:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/18/2025 10:13:00 AM. 50 Economy ticket for $427 per person are available. Travel duration is 4h 13m
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Delta Air Lines11h 27m06:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:12 PMQuerétaro AirportQuerétaro Airport0EconomyA Flight from Delta Air Lines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 6:45:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/18/2025 6:12:00 PM. 50 Economy ticket for $719 per person are available. Travel duration is 11h 27m
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United Airlines15h 10m05:49 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center8:59 PMQuerétaro AirportQuerétaro Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 5:49:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/18/2025 8:59:00 PM. 50 Economy ticket for $647 per person are available. Travel duration is 15h 10m
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Frontier Airlines25h 50m07:00 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center8:50 AMQuerétaro AirportQuerétaro Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 7:00:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/19/2025 8:50:00 AM. 50 Economy ticket for $375 per person are available. Travel duration is 25h 50m
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Spirit Airlines34h 12m06:05 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:17 PMQuerétaro AirportQuerétaro Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 12/18/2025 6:05:00 AM to Querétaro Airport, Querétaro Airport (Mexico) arriving at 12/19/2025 4:17:00 PM. 50 Economy ticket for $332 per person are available. Travel duration is 34h 12m
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FlixBus47h 20m010:10 AMChicago95th Red Line Station9:30 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/18/2025 10:10:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 9:30:00 AM. 50 Economy ticket for $251 per person are available. Travel duration is 47h 20m
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FlixBus47h 45m09:45 AMChicagoDowntown Bus Station9:30 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/18/2025 9:45:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 9:30:00 AM. 50 Economy ticket for $254 per person are available. Travel duration is 47h 45m
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Greyhound US56h 40m010:00 AMChicagoCanal & Van Buren6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/18/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 6:40:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 56h 40m
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Greyhound US56h 40m010:00 AMChicagoUnion Station6:40 PMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/18/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 6:40:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 56h 40m
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Greyhound US59h 30m010:00 PMChicagoCanal & Van Buren9:30 AMSantiago de QueretaroCentro Comercial Galeria0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/18/2025 10:00:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/21/2025 9:30:00 AM. 50 Economy ticket for $253 per person are available. Travel duration is 59h 30m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Chicago to Santiago de Queretaro
What are the most popular stations in Chicago and Santiago de Queretaro?
In Chicago, you will usually depart from California & 35th Street Bus Stop, Downtown Bus Station or 95th Red Line Station, while in Santiago de Queretaro you will be arriving at Terminal Norte, Centro Comercial Galeria or 5 de Febrero Acceso a Plaza Galerías Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Santiago de Queretaro from Chicago? With 5 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and Santiago de Queretaro, you can pay as low as $222 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Volaris: you will get to Santiago de Queretaro in just 4h 13m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and Santiago de Queretaro are Greyhound US, FlixBus and Spirit Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and Santiago de Queretaro is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to San Isidro Miranda, and look at flights from Chicago Midway Airport, and landing at Querétaro Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to Santiago de Queretaro?
The most popular companies between Chicago and Santiago de Queretaro, are Greyhound US, FlixBus and Spirit Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Spirit Airlines, Frontier Airlines, Volaris and 2 more.
All you need to know when you travel from Chicago to Santiago de Queretaro
Check all information on comfort and services on all modes of transports from Chicago to Santiago de Queretaro. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to Santiago de Queretaro
How can I reach Santiago de Queretaro from Chicago?
Every day, there are on average 5 connections between Bus and Flight, with which you can get to Santiago de Queretaro from Chicago.
How far is Santiago de Queretaro from Chicago?
The distance between Chicago and Santiago de Queretaro is 1,648.5 miles.
What is the most ecofriendly mode of transport between Chicago and Santiago de Queretaro?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 72 kgs of CO2, a train 93 kgs, a car 451 kgs, and a flight 653 kgs.
What is the cheapest mode of transport from Chicago to Santiago de Queretaro?
You can get to Santiago de Queretaro with just $222 by taking a Bus from Greyhound US.
What is the fastest way to get from Chicago to Santiago de Queretaro?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago de Queretaro in just 4h 13m with a Flight from Volaris.
More routes to Chicago and to Santiago de Queretaro
Looking for more options? Here you can see the most popular routes to Chicago and to Santiago de Queretaro. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Buffalo, NY to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Guadalajara, JC to Chicago
- Houston to Chicago
- Los Angeles to Chicago
- Louisville, KY to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Monterrey, NL to Chicago
- Nashville to Chicago
- New York to Chicago
- Pearson Toronto Airport to Chicago
- Philadelphia to Chicago
- Phoenix, AZ to Chicago
- San Antonio, TX to Chicago
- San Luis Potosí to Chicago
- Santiago de Queretaro to Chicago
- St. Louis, MO to Chicago
- Toronto, ON to Chicago
- Trips to Santiago de Queretaro
- Acapulco, GR to Santiago de Queretaro
- Chihuahua to Santiago de Queretaro
- Ciudad Juárez to Santiago de Queretaro
- Colima to Santiago de Queretaro
- Culiacán Rosales to Santiago de Queretaro
- Durango, DG to Santiago de Queretaro
- Guadalajara, JC to Santiago de Queretaro
- Guanajuato to Santiago de Queretaro
- Ixtapa to Santiago de Queretaro
- Matamoros to Santiago de Queretaro
- Mazatlán to Santiago de Queretaro
- Mexicali to Santiago de Queretaro
- Mexico City to Santiago de Queretaro
- Monterrey, NL to Santiago de Queretaro
- Piedras Negras to Santiago de Queretaro
- Puerto Vallarta to Santiago de Queretaro
- Reynosa to Santiago de Queretaro
- Saltillo to Santiago de Queretaro
- Tepic to Santiago de Queretaro
- Tijuana, BC to Santiago de Queretaro
- Torreón, CO to Santiago de Queretaro
- Zapopan to Santiago de Queretaro
- Zihuatanejo to Santiago de Queretaro

