Compare all timetables for the bus from Chicago to Santiago de Queretaro
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 49h 20m | 9:45 AM | Chicago | Downtown Bus Station | 10:05 AM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $160 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 8/1/2026 9:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 10:05:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 49h 20m
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| Greyhound US | 57h 25m | 10:15 AM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $162 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/1/2026 10:15:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 6:40:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 57h 25m
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| Greyhound US | 68h 30m | 11:10 PM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $162 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/1/2026 11:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/4/2026 6:40:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 68h 30m
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| Greyhound US | 45h 0m | 10:40 PM | Chicago | Downtown Bus Station | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $183 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 8/1/2026 10:40:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 6:40:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 45h 0m
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| FlixBus | 59h 10m | 11:55 PM | Chicago | 95th Red Line Station | 10:05 AM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $233 |
A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/1/2026 11:55:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/4/2026 10:05:00 AM. 50 Economy ticket for $233 per person are available. Travel duration is 59h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 52h 0m | 9:45 AM | Chicago | Downtown Bus Station | 12:45 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $179 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 8/3/2026 9:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/5/2026 12:45:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 52h 0m
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| Greyhound US | 57h 25m | 10:15 AM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $181 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/3/2026 10:15:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/5/2026 6:40:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 57h 25m
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| Greyhound US | 45h 0m | 10:40 PM | Chicago | Downtown Bus Station | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $188 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 8/3/2026 10:40:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/5/2026 6:40:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 45h 0m
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| FlixBus | 56h 0m | 5:45 AM | Chicago | 95th Red Line Station | 12:45 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $212 |
A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/3/2026 5:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/5/2026 12:45:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 56h 0m
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| Greyhound US | 68h 30m | 11:10 PM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $214 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/3/2026 11:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/6/2026 6:40:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 68h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 45h 0m | 10:40 PM | Chicago | Downtown Bus Station | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $175 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 8/4/2026 10:40:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/6/2026 6:40:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 45h 0m
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| Greyhound US | 57h 25m | 10:15 AM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $177 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/4/2026 10:15:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/6/2026 6:40:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 57h 25m
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| Greyhound US | 68h 30m | 11:10 PM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $195 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/4/2026 11:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/7/2026 6:40:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 68h 30m
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| FlixBus | 59h 10m | 11:55 PM | Chicago | 95th Red Line Station | 10:05 AM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $217 |
A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/4/2026 11:55:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/7/2026 10:05:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 59h 10m
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| FlixBus | 50h 35m | 5:05 PM | Chicago | 95th Red Line Station | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $227 |
A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/4/2026 5:05:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/6/2026 6:40:00 PM. 50 Economy ticket for $227 per person are available. Travel duration is 50h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 56h 40m | 6:30 PM | Chicago | 95th Red Line Station | 2:10 AM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $263 |
A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/5/2026 6:30:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/8/2026 2:10:00 AM. 50 Economy ticket for $263 per person are available. Travel duration is 56h 40m
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| FlixBus | 53h 40m | 5:25 AM | Chicago | 95th Red Line Station | 10:05 AM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $283 |
A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/5/2026 5:25:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/7/2026 10:05:00 AM. 50 Economy ticket for $283 per person are available. Travel duration is 53h 40m
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| FlixBus | 49h 20m | 9:45 AM | Chicago | Downtown Bus Station | 10:05 AM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $286 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 8/5/2026 9:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/7/2026 10:05:00 AM. 50 Economy ticket for $286 per person are available. Travel duration is 49h 20m
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| Greyhound US | 45h 0m | 10:40 PM | Chicago | Downtown Bus Station | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $302 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 8/5/2026 10:40:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/7/2026 6:40:00 PM. 50 Economy ticket for $302 per person are available. Travel duration is 45h 0m
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| Greyhound US | 57h 25m | 10:15 AM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $373 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/5/2026 10:15:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/7/2026 6:40:00 PM. 50 Economy ticket for $373 per person are available. Travel duration is 57h 25m
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Greyhound US65h 0m01:45 PMChicago95th Red Line Station5:55 AMMcAllen, TXCentral Bus Station0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 8/2/2026 1:45:00 PM to Central Bus Station, McAllen, TX (USA) arriving at 8/4/2026 5:55:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 40h 10m
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Greyhound US21h 15m09:30 AMMcAllen, TXCentral Bus Station5:45 AMSantiago de QueretaroProl Zaragoza Y City Club Las Plazas Bus Stop0EconomyA Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 8/4/2026 9:30:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/5/2026 5:45:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 21h 15m
Waiting Time 3h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 49h 20m | 9:45 AM | Chicago | Downtown Bus Station | 10:05 AM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $135 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 8/7/2026 9:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/9/2026 10:05:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 49h 20m
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| Greyhound US | 45h 0m | 10:40 PM | Chicago | Downtown Bus Station | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $140 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 8/7/2026 10:40:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/9/2026 6:40:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 45h 0m
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| Greyhound US | 68h 30m | 11:10 PM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $162 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/7/2026 11:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/10/2026 6:40:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 68h 30m
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| Greyhound US | 57h 25m | 10:15 AM | Chicago | Canal & Van Buren | 6:40 PM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $164 |
A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/7/2026 10:15:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/9/2026 6:40:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 57h 25m
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| FlixBus | 53h 20m | 5:45 AM | Chicago | 95th Red Line Station | 10:05 AM | Santiago de Queretaro | Prol Zaragoza Y City Club Las Plazas Bus Stop | Economy | $213 |
A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/7/2026 5:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/9/2026 10:05:00 AM. 50 Economy ticket for $213 per person are available. Travel duration is 53h 20m
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Best Price Offer: The price for the cheapest bus from Chicago to Santiago de Queretaro is $132 on 7/27/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Chicago and Santiago de Queretaro
Facts about the bus from Chicago to Santiago de Queretaro
Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from Chicago to Santiago de Queretaro in one click! Book your bus ticket from Chicago to Santiago de Queretaro starting from $132!
| Cheapest Bus | $132 |
| Fastest Bus | 44h 0m |
| Earliest Bus | 9:45 AM |
| Latest Bus | 11:10 PM |
| Daily Bus Routes | 7 Ø |
| Distance | 1,648.5 miles |
| Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from Chicago to Santiago de Queretaro
Every day, 7 buses from 2 bus companies leave Chicago for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/01/2026 and for the following days.
The cheapest time to travel from Chicago to Santiago de Queretaro
How to save money travelling from Chicago to Santiago de Queretaro
Book the ticket from Chicago to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Santiago de Queretaro are also emptier.Beloved bus companies from Chicago to Santiago de Queretaro
FlixBus from Chicago to Santiago de Queretaro
Here you will find the key facts about the FlixBus bus route Chicago to Santiago de Queretaro:
| Cheapest Price | $135 |
| Fastest Bus | 47h 15m |
| Earliest Bus | 9:45 AM |
| Last Bus | 7:25 PM |
| Daily Connections | 4 Ø |
| Found on | 8/1/2026 |
All bus stations and stops in Chicago and Santiago de Queretaro
In the map below, you can see where to find all bus stations in Chicago and Santiago de Queretaro.
Service and Comfort on the bus from Chicago to Santiago de Queretaro
FAQs about the Chicago to Santiago de Queretaro bus
How much does a Chicago Santiago de Queretaro bus trip cost?
How much could I save by comparing buses from Chicago to Santiago de Queretaro?
On average, how many connections are available from Chicago to Santiago de Queretaro each day?
How long does a bus journey from Chicago to Santiago de Queretaro take?
What time is the first bus from Chicago to Santiago de Queretaro?
What time is the last bus from Chicago to Santiago de Queretaro?
Which bus companies operate the Chicago Santiago de Queretaro route?
Is there a direct bus between Chicago and Santiago de Queretaro?
What can I take with me on the Chicago to Santiago de Queretaro bus route?
What equipment is available for the Chicago Santiago de Queretaro bus route?
How does CheckMyBus find the best bus deals from Chicago to Santiago de Queretaro?
How does CheckMyBus technology work for trips from Chicago to Santiago de Queretaro?
Available seat classes which are offered on the bus route Chicago to Santiago de Queretaro
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Chicago and to Santiago de Queretaro
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- Bus Routes to Santiago de Queretaro
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