Bus Gainesville, FL to Chicago: Compare prices and save money

Compare all timetables for the bus from Gainesville, FL to Chicago

Here is a selection of the cheapest bus trips from the schedule from Gainesville, FL to Chicago from various bus operators like FlixBus or Greyhound US for the next days.

today

$135

tomorrow

Sunday

Monday

Tuesday

Wednesday

Thursday

$139

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 55m	2:40 PM	Gainesville, FL	Rosa Parks Transfer station	2:35 PM	Chicago	Downtown Bus Station	Economy	$135	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/5/2025 2:40:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 2:35:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 24h 55m
FlixBus	23h 15m	5:00 PM	Gainesville, FL	Rosa Parks Transfer station	3:15 PM	Chicago	Downtown Bus Station	Economy	$135	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/5/2025 5:00:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 3:15:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 23h 15m
FlixBus	24h 30m	2:40 PM	Gainesville, FL	Rosa Parks Transfer station	2:10 PM	Chicago	Union Station	Economy	$135	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/5/2025 2:40:00 PM to Union Station, Chicago (USA) arriving at 12/6/2025 2:10:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 24h 30m
Greyhound US	30h 50m	8:20 AM	Gainesville, FL	Greyhound Bus Station	2:10 PM	Chicago	Union Station	Economy	$135	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/5/2025 8:20:00 AM to Union Station, Chicago (USA) arriving at 12/6/2025 2:10:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 30h 50m
Greyhound US	28h 10m	8:20 AM	Gainesville, FL	Greyhound Bus Station	11:30 AM	Chicago	Downtown Bus Station	Economy	$137	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/5/2025 8:20:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 11:30:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 28h 10m

Did you know that if you travel from Gainesville, FL to Chicago via Atlanta, GA, you can save more than $17? You can find the corresponding connections below.
- Busbud
  
  28h 10m
  
  0
  
  5:00 PM
  
  Gainesville, FL
  Rosa Parks Transfer station
  
  11:10 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $41
  
  A Bus from Busbud goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/6/2025 5:00:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/6/2025 11:10:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 6h 10m
- Busbud
  
  16h 20m
  
  0
  
  4:50 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  8:10 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $77
  
  A Bus from Busbud goes from Garnett Transit Station, Atlanta, GA (USA) at 12/7/2025 4:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/7/2025 8:10:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 16h 20m
Travel time is 5h 55m longer, but you will save $17

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 10m	8:20 AM	Gainesville, FL	Greyhound Bus Station	11:30 AM	Chicago	Downtown Bus Station	Economy	$139	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/11/2025 8:20:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 11:30:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 28h 10m
FlixBus	24h 55m	2:40 PM	Gainesville, FL	Rosa Parks Transfer station	2:35 PM	Chicago	Downtown Bus Station	Economy	$140	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/11/2025 2:40:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 2:35:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 24h 55m
FlixBus	23h 15m	5:00 PM	Gainesville, FL	Rosa Parks Transfer station	3:15 PM	Chicago	Downtown Bus Station	Economy	$140	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/11/2025 5:00:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 3:15:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 23h 15m
FlixBus	24h 30m	2:40 PM	Gainesville, FL	Rosa Parks Transfer station	2:10 PM	Chicago	Union Station	Economy	$140	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/11/2025 2:40:00 PM to Union Station, Chicago (USA) arriving at 12/12/2025 2:10:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 24h 30m
Greyhound US	30h 50m	8:20 AM	Gainesville, FL	Greyhound Bus Station	2:10 PM	Chicago	Union Station	Economy	$140	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/11/2025 8:20:00 AM to Union Station, Chicago (USA) arriving at 12/12/2025 2:10:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 30h 50m

Did you know that if you travel from Gainesville, FL to Chicago via Atlanta, GA, you can save more than $21? You can find the corresponding connections below.
- Busbud
  
  28h 10m
  
  0
  
  5:00 PM
  
  Gainesville, FL
  Rosa Parks Transfer station
  
  11:10 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $41
  
  A Bus from Busbud goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/6/2025 5:00:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/6/2025 11:10:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 6h 10m
- Busbud
  
  16h 20m
  
  0
  
  4:50 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  8:10 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $77
  
  A Bus from Busbud goes from Garnett Transit Station, Atlanta, GA (USA) at 12/7/2025 4:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/7/2025 8:10:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 16h 20m
Travel time is 5h 55m longer, but you will save $21

Best Price Offer: The price for the cheapest bus from Gainesville, FL to Chicago is $135 on 12/5/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Gainesville, FL and Chicago

See here how frequent the connections between Gainesville, FL and Chicago are, during different times and days of the week.

Thursday is the busiest day, with more than 13 daily buses from Gainesville, FL to Chicago. Friday has instead the fewest connections, with only 12 daily coaches between Gainesville, FL and Chicago.

The busiest time of the day is the Afternoon, with 11 buses from Gainesville, FL to Chicago, while Night sees the fewest connections between Gainesville, FL and Chicago, with 2 offers.

Facts about the bus from Gainesville, FL to Chicago

Compare all providers like FlixBus and Greyhound US that travel 12 times every day by bus from Gainesville, FL to Chicago in one click! Book your bus ticket from Gainesville, FL to Chicago starting from $135!

Cheapest Bus	$135
Fastest Bus	22h 15m
Earliest Bus	1:10 AM
Latest Bus	10:40 PM
Daily Bus Routes	12 Ø
Distance	895.9 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Gainesville, FL to Chicago

Every day, 12 buses from 2 bus companies leave Gainesville, FL for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$135

Saturday 12/06

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

$139

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

$163

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Gainesville, FL to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Gainesville, FL to Chicago, for the next 30 days.

With a price starting from $135, Friday is the cheapest day for a bus from Gainesville, FL to Chicago. Thursday instead is the most expensive day with prices starting from $139.

Afternoon is the cheapest day time for bus tickets from Gainesville, FL to Chicago, with $135. Evening is the most expensive time of the day with prices starting from $136.

How to save money travelling from Gainesville, FL to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Gainesville, FL to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Gainesville, FL to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Gainesville, FL to Chicago are also emptier.

All bus stations and stops in Gainesville, FL and Chicago

In the map below, you can see where to find all bus stations in Gainesville, FL and Chicago.

Rosa Parks Transfer station

SE 3rd St 700

Greyhound Bus Station

Northeast 23rd Avenue 101

North Walmart Supercenter Bus Stop

Westgate Plaza Bus Stop

Central Bus Station

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Gainesville, FL to Chicago

Want to know which seat classes are available on the buses from Gainesville, FL to Chicago? Or which bus companies serve the route Gainesville, FL to Chicago? Below you will find answers to your questions.

FAQs about the Gainesville, FL to Chicago bus

How much does a Gainesville, FL Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $135 and takes 23h 55m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Gainesville, FL to Chicago?

This route is offered by 2 companies with a range of ticket prices between $135 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Gainesville, FL to Chicago each day?

Every day, the Gainesville, FL to Chicago bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Gainesville, FL to Chicago take?

The fastest bus from Gainesville, FL to Chicago is offered by FlixBus and takes 22h 15m. Bus tickets for this connection cost $135. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Gainesville, FL to Chicago?

The earliest bus arriving in Chicago from Gainesville, FL starts at 1:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Gainesville, FL to Chicago?

The latest bus trip departing from Gainesville, FL for Chicago starts at 10:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Gainesville, FL Chicago route?

When traveling by bus from Gainesville, FL to Chicago, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Gainesville, FL and Chicago?

You can check all the direct connections between Gainesville, FL and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Gainesville, FL to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Gainesville, FL Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Gainesville, FL Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Gainesville, FL to Chicago on your planned travel date.

Available seat classes which are offered on the bus route Gainesville, FL to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Gainesville, FL and to Chicago

Here’s an overview of the most popular bus routes to Gainesville, FL and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!