Bus San Diego to Santiago de Queretaro

Compare all timetables for the bus from San Diego to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from San Diego to Santiago de Queretaro from various bus operators like FlixBus or Greyhound US for the next days.

today

$220

tomorrow

$220

Wednesday

$220

Thursday

Friday

Saturday

$259

Sunday

$302

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	58h 5m	7:35 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 4/27/2026 7:35:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/29/2026 6:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 58h 5m
FlixBus	57h 45m	7:55 AM	San Diego	La Jolla Village	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 4/27/2026 7:55:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/29/2026 6:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 57h 45m
FlixBus	59h 35m	1:35 PM	San Diego	La Jolla Village	2:10 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 4/27/2026 1:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/30/2026 2:10:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 59h 35m
Greyhound US	55h 50m	9:50 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 4/27/2026 9:50:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/29/2026 6:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 55h 50m
Greyhound US	70h 5m	7:35 PM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 4/27/2026 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/30/2026 6:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 70h 5m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	58h 5m	7:35 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 4/28/2026 7:35:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/30/2026 6:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 58h 5m
FlixBus	57h 45m	7:55 AM	San Diego	La Jolla Village	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 4/28/2026 7:55:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/30/2026 6:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 57h 45m
FlixBus	59h 35m	1:35 PM	San Diego	La Jolla Village	2:10 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 4/28/2026 1:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/1/2026 2:10:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 59h 35m
Greyhound US	66h 25m	6:45 AM	San Diego	Old Town Transit Center	2:10 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$221	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 4/28/2026 6:45:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/1/2026 2:10:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 66h 25m
Greyhound US	61h 30m	7:35 PM	San Diego	Old Town Transit Center	10:05 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$235	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 4/28/2026 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/1/2026 10:05:00 AM. 50 Economy ticket for $235 per person are available. Travel duration is 61h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	58h 5m	7:35 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 4/29/2026 7:35:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/1/2026 6:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 58h 5m
FlixBus	57h 45m	7:55 AM	San Diego	La Jolla Village	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 4/29/2026 7:55:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/1/2026 6:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 57h 45m
FlixBus	59h 35m	1:35 PM	San Diego	La Jolla Village	2:10 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 4/29/2026 1:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/2/2026 2:10:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 59h 35m
Greyhound US	66h 25m	6:45 AM	San Diego	Old Town Transit Center	2:10 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$221	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 4/29/2026 6:45:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/2/2026 2:10:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 66h 25m
Greyhound US	61h 30m	7:35 PM	San Diego	Old Town Transit Center	10:05 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$223	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 4/29/2026 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/2/2026 10:05:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 61h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	61h 30m	7:35 PM	San Diego	Old Town Transit Center	10:05 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$259	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/2/2026 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/5/2026 10:05:00 AM. 50 Economy ticket for $259 per person are available. Travel duration is 61h 30m
Greyhound US	55h 50m	9:50 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$278	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/2/2026 9:50:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/4/2026 6:40:00 PM. 50 Economy ticket for $278 per person are available. Travel duration is 55h 50m
FlixBus	58h 5m	7:35 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$281	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/2/2026 7:35:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/4/2026 6:40:00 PM. 50 Economy ticket for $281 per person are available. Travel duration is 58h 5m
FlixBus	57h 45m	7:55 AM	San Diego	La Jolla Village	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$281	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/2/2026 7:55:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/4/2026 6:40:00 PM. 50 Economy ticket for $281 per person are available. Travel duration is 57h 45m
FlixBus	59h 35m	1:35 PM	San Diego	La Jolla Village	2:10 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$329	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/2/2026 1:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/5/2026 2:10:00 AM. 50 Economy ticket for $329 per person are available. Travel duration is 59h 35m

Did you know that if you travel from San Diego to Santiago de Queretaro via Tijuana, BC, you can save more than $53? You can find the corresponding connections below.
- Tufesa International
  
  39h 43m
  
  0
  
  5:00 AM
  
  San Diego
  San Ysidro Transit Center
  
  6:00 AM
  
  Tijuana, BC
  Central Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from Tufesa International goes from San Ysidro Transit Center, San Diego (USA) at 4/28/2026 5:00:00 AM to Central Bus Station, Tijuana, BC (Mexico) arriving at 4/28/2026 6:00:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 1h 0m
- Aguacaliente
  
  37h 28m
  
  0
  
  7:15 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  9:43 PM
  
  Santiago de Queretaro
  Terminal Norte
  
  0
  
  Economy
  
  $195
  
  A Bus from Aguacaliente goes from Centro Bus Stop, Tijuana, BC (Mexico) at 4/28/2026 7:15:00 AM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 4/29/2026 9:43:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 37h 28m
Travel Time is 17h 7m shorter, and you will save $53

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	55h 50m	9:50 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$302	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/3/2026 9:50:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/5/2026 6:40:00 PM. 50 Economy ticket for $302 per person are available. Travel duration is 55h 50m
Greyhound US	70h 5m	7:35 PM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$303	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/3/2026 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/6/2026 6:40:00 PM. 50 Economy ticket for $303 per person are available. Travel duration is 70h 5m
FlixBus	58h 5m	7:35 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$306	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/3/2026 7:35:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/5/2026 6:40:00 PM. 50 Economy ticket for $306 per person are available. Travel duration is 58h 5m
FlixBus	57h 45m	7:55 AM	San Diego	La Jolla Village	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$306	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/3/2026 7:55:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/5/2026 6:40:00 PM. 50 Economy ticket for $306 per person are available. Travel duration is 57h 45m
FlixBus	59h 35m	1:35 PM	San Diego	La Jolla Village	2:10 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$310	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/3/2026 1:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 5/6/2026 2:10:00 AM. 50 Economy ticket for $310 per person are available. Travel duration is 59h 35m

Did you know that if you travel from San Diego to Santiago de Queretaro via Tijuana, BC, you can save more than $96? You can find the corresponding connections below.
- Tufesa International
  
  39h 43m
  
  0
  
  5:00 AM
  
  San Diego
  San Ysidro Transit Center
  
  6:00 AM
  
  Tijuana, BC
  Central Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from Tufesa International goes from San Ysidro Transit Center, San Diego (USA) at 4/28/2026 5:00:00 AM to Central Bus Station, Tijuana, BC (Mexico) arriving at 4/28/2026 6:00:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 1h 0m
- Aguacaliente
  
  37h 28m
  
  0
  
  7:15 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  9:43 PM
  
  Santiago de Queretaro
  Terminal Norte
  
  0
  
  Economy
  
  $195
  
  A Bus from Aguacaliente goes from Centro Bus Stop, Tijuana, BC (Mexico) at 4/28/2026 7:15:00 AM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 4/29/2026 9:43:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 37h 28m
Travel Time is 17h 7m shorter, and you will save $96

Best Price Offer: The price for the cheapest bus from San Diego to Santiago de Queretaro is $215 on 5/1/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Diego and Santiago de Queretaro

See here how frequent the connections between San Diego and Santiago de Queretaro are, during different times and days of the week.

Sunday is the busiest day, with more than 7 daily buses from San Diego to Santiago de Queretaro. Sunday has instead the fewest connections, with only 7 daily coaches between San Diego and Santiago de Queretaro.

The busiest time of the day is the Morning, with 20 buses from San Diego to Santiago de Queretaro, while Evening sees the fewest connections between San Diego and Santiago de Queretaro, with 5 offers.

Facts about the bus from San Diego to Santiago de Queretaro

Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from San Diego to Santiago de Queretaro in one click! Book your bus ticket from San Diego to Santiago de Queretaro starting from $215!

Cheapest Bus	$215
Fastest Bus	56h 50m
Earliest Bus	7:35 AM
Latest Bus	7:35 PM
Daily Bus Routes	7 Ø
Distance	1,331.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from San Diego to Santiago de Queretaro

Every day, 7 buses from 2 bus companies leave San Diego for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/26

Monday 04/27

$216

Tuesday 04/28

$216

Wednesday 04/29

$220

Thursday 04/30

Friday 05/01

$215

Saturday 05/02

$259

Sunday 05/03

$296

Monday 05/04

$217

Tuesday 05/05

$216

Wednesday 05/06

Thursday 05/07

Friday 05/08

$217

Saturday 05/09

$219

Sunday 05/10

$219

Monday 05/11

$219

Tuesday 05/12

$218

Wednesday 05/13

$222

Thursday 05/14

Friday 05/15

$220

Saturday 05/16

$220

Sunday 05/17

$224

Monday 05/18

$220

Tuesday 05/19

$220

Wednesday 05/20

$220

Thursday 05/21

$219

Friday 05/22

$224

Saturday 05/23

The cheapest time to travel from San Diego to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Santiago de Queretaro, for the next 30 days.

With a price starting from $216, Monday is the cheapest day for a bus from San Diego to Santiago de Queretaro. Wednesday instead is the most expensive day with prices starting from $220.

Morning is the cheapest day time for bus tickets from San Diego to Santiago de Queretaro, with $220. Morning is the most expensive time of the day with prices starting from $220.

How to save money travelling from San Diego to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Santiago de Queretaro are also emptier.

Beloved bus companies from San Diego to Santiago de Queretaro

These are the most booked bus companies between San Diego to Santiago de Queretaro from our users.

Greyhound US from San Diego to Santiago de Queretaro

Here you will find the key facts about the Greyhound US bus route San Diego to Santiago de Queretaro:

Cheapest Price	$220
Fastest Bus	56h 50m
Earliest Bus	9:50 AM
Last Bus	7:35 PM
Daily Connections	2 Ø
Found on	4/2/2026

All bus stations and stops in San Diego and Santiago de Queretaro

In the map below, you can see where to find all bus stations in San Diego and Santiago de Queretaro.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Prol Zaragoza Y City Club Las Plazas Bus Stop

Prol Zaragoza Y City Club Las Plazas Prol Zaragoza Y City Club Las Plazas

Service and Comfort on the bus from San Diego to Santiago de Queretaro

Want to know which seat classes are available on the buses from San Diego to Santiago de Queretaro? Or which bus companies serve the route San Diego to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the San Diego to Santiago de Queretaro bus

How much does a San Diego Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $215 and takes 59h 5m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from San Diego to Santiago de Queretaro?

This route is offered by 2 companies with a range of ticket prices between $215 and $331. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from San Diego to Santiago de Queretaro each day?

Every day, the San Diego to Santiago de Queretaro bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Santiago de Queretaro take?

The fastest bus from San Diego to Santiago de Queretaro is offered by Greyhound US and takes 56h 50m. Bus tickets for this connection cost $220. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from San Diego starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Santiago de Queretaro?

The latest bus trip departing from San Diego for Santiago de Queretaro starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Santiago de Queretaro route?

When traveling by bus from San Diego to Santiago de Queretaro, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Santiago de Queretaro?

You can check all the direct connections between San Diego and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Santiago de Queretaro on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to Santiago de Queretaro?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between San Diego and Santiago de Queretaro. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to Santiago de Queretaro?

Prices and availability for 7 trips between San Diego and Santiago de Queretaro change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to Santiago de Queretaro

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to San Diego and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!