Bus San Diego to Santiago de Queretaro

Compare all timetables for the bus from San Diego to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from San Diego to Santiago de Queretaro from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Sunday

Monday

Tuesday

Wednesday

$220

Thursday

$226

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	59h 5m	1:15 PM	San Diego	San Ysidro Transit Center	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from San Ysidro Transit Center, San Diego (USA) at 12/10/2025 1:15:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/13/2025 2:20:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 59h 5m
Greyhound US	65h 35m	6:45 AM	San Diego	Old Town Transit Center	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$223	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/10/2025 6:45:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/13/2025 2:20:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 65h 35m
FlixBus	58h 35m	1:45 PM	San Diego	Seaport Village	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$223	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 12/10/2025 1:45:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/13/2025 2:20:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 58h 35m
FlixBus	58h 25m	7:35 AM	San Diego	Old Town Transit Center	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$224	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/10/2025 7:35:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/12/2025 8:00:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 58h 25m
Greyhound US	59h 55m	7:35 PM	San Diego	Old Town Transit Center	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$226	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/10/2025 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/13/2025 9:30:00 AM. 50 Economy ticket for $226 per person are available. Travel duration is 59h 55m

Did you know that if you travel from San Diego to Santiago de Queretaro via Tijuana, BC, you can save more than $40? You can find the corresponding connections below.
- Busbud
  
  47h 30m
  
  0
  
  11:55 AM
  
  San Diego
  Old Town Transit Center
  
  2:00 PM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/10/2025 11:55:00 AM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/10/2025 2:00:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 5m
- ClickBus MX
  
  41h 25m
  
  0
  
  6:00 PM
  
  Tijuana, BC
  Centro Bus Stop
  
  1:25 PM
  
  Santiago de Queretaro
  Terminal Norte
  
  0
  
  Economy
  
  $174
  
  A Bus from ClickBus MX goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/10/2025 6:00:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/12/2025 1:25:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 41h 25m
Travel Time is 12h 55m shorter, and you will save $40

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	58h 10m	2:10 PM	San Diego	La Jolla Village	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$226	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 12/11/2025 2:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/14/2025 2:20:00 AM. 50 Economy ticket for $226 per person are available. Travel duration is 58h 10m
FlixBus	58h 35m	1:45 PM	San Diego	Seaport Village	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$227	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 12/11/2025 1:45:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/14/2025 2:20:00 AM. 50 Economy ticket for $227 per person are available. Travel duration is 58h 35m
FlixBus	62h 55m	9:25 AM	San Diego	Old Town Transit Center	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$228	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/11/2025 9:25:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/14/2025 2:20:00 AM. 50 Economy ticket for $228 per person are available. Travel duration is 62h 55m
Greyhound US	56h 0m	10:00 AM	San Diego	Old Town Transit Center	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$232	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/11/2025 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/13/2025 8:00:00 PM. 50 Economy ticket for $232 per person are available. Travel duration is 56h 0m
Greyhound US	59h 55m	7:35 PM	San Diego	Old Town Transit Center	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$267	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/11/2025 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/14/2025 9:30:00 AM. 50 Economy ticket for $267 per person are available. Travel duration is 59h 55m

Did you know that if you travel from San Diego to Santiago de Queretaro via Tijuana, BC, you can save more than $46? You can find the corresponding connections below.
- Busbud
  
  47h 30m
  
  0
  
  11:55 AM
  
  San Diego
  Old Town Transit Center
  
  2:00 PM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/10/2025 11:55:00 AM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/10/2025 2:00:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 5m
- ClickBus MX
  
  41h 25m
  
  0
  
  6:00 PM
  
  Tijuana, BC
  Centro Bus Stop
  
  1:25 PM
  
  Santiago de Queretaro
  Terminal Norte
  
  0
  
  Economy
  
  $174
  
  A Bus from ClickBus MX goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/10/2025 6:00:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/12/2025 1:25:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 41h 25m
Travel Time is 10h 30m shorter, and you will save $46

Best Price Offer: The price for the cheapest bus from San Diego to Santiago de Queretaro is $219 on 12/2/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between San Diego and Santiago de Queretaro

See here how frequent the connections between San Diego and Santiago de Queretaro are, during different times and days of the week.

Thursday is the busiest day, with more than 9 daily buses from San Diego to Santiago de Queretaro. Wednesday has instead the fewest connections, with only 8 daily coaches between San Diego and Santiago de Queretaro.

The busiest time of the day is the Morning, with 8 buses from San Diego to Santiago de Queretaro, while Evening sees the fewest connections between San Diego and Santiago de Queretaro, with 3 offers.

Facts about the bus from San Diego to Santiago de Queretaro

Compare all providers like FlixBus and Greyhound US that travel 8 times every day by bus from San Diego to Santiago de Queretaro in one click! Book your bus ticket from San Diego to Santiago de Queretaro starting from $219!

Cheapest Bus	$219
Fastest Bus	58h 0m
Earliest Bus	6:45 AM
Latest Bus	7:35 PM
Daily Bus Routes	8 Ø
Distance	1,331.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from San Diego to Santiago de Queretaro

Every day, 8 buses from 2 bus companies leave San Diego for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

$220

Thursday 12/11

$226

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

$223

Tuesday 12/16

$230

Wednesday 12/17

Thursday 12/18

$228

Friday 12/19

$261

Saturday 12/20

$230

Sunday 12/21

$229

Monday 12/22

$241

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from San Diego to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Santiago de Queretaro, for the next 30 days.

With a price starting from $220, Wednesday is the cheapest day for a bus from San Diego to Santiago de Queretaro. Thursday instead is the most expensive day with prices starting from $226.

Afternoon is the cheapest day time for bus tickets from San Diego to Santiago de Queretaro, with $220. Evening is the most expensive time of the day with prices starting from $226.

How to save money travelling from San Diego to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Santiago de Queretaro are also emptier.

Beloved bus companies from San Diego to Santiago de Queretaro

These are the most booked bus companies between San Diego to Santiago de Queretaro from our users.

Greyhound US from San Diego to Santiago de Queretaro

Here you will find the key facts about the Greyhound US bus route San Diego to Santiago de Queretaro:

Cheapest Price	$223
Fastest Bus	58h 0m
Earliest Bus	6:45 AM
Last Bus	7:35 PM
Daily Connections	2 Ø
Found on	12/3/2025

All bus stations and stops in San Diego and Santiago de Queretaro

In the map below, you can see where to find all bus stations in San Diego and Santiago de Queretaro.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

Service and Comfort on the bus from San Diego to Santiago de Queretaro

Want to know which seat classes are available on the buses from San Diego to Santiago de Queretaro? Or which bus companies serve the route San Diego to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the San Diego to Santiago de Queretaro bus

How much does a San Diego Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $219 and takes 61h 5m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from San Diego to Santiago de Queretaro?

This route is offered by 2 companies with a range of ticket prices between $219 and $281. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from San Diego to Santiago de Queretaro each day?

Every day, the San Diego to Santiago de Queretaro bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Santiago de Queretaro take?

The fastest bus from San Diego to Santiago de Queretaro is offered by Greyhound US and takes 58h 0m. Bus tickets for this connection cost $232. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from San Diego starts at 6:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Santiago de Queretaro?

The latest bus trip departing from San Diego for Santiago de Queretaro starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Santiago de Queretaro route?

When traveling by bus from San Diego to Santiago de Queretaro, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Santiago de Queretaro?

You can check all the direct connections between San Diego and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Santiago de Queretaro on your planned travel date.

Available seat classes which are offered on the bus route San Diego to Santiago de Queretaro

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to San Diego and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!