Bus San Diego to Santiago de Queretaro

Compare all timetables for the bus from San Diego to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from San Diego to Santiago de Queretaro from various bus operators like FlixBus or Greyhound US for the next days.

today

$215

tomorrow

$212

Saturday

Sunday

Monday

$209

Tuesday

Wednesday

$212

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	56h 15m	9:25 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$215	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 10/29/2026 9:25:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 10/31/2026 6:40:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 56h 15m
FlixBus	52h 30m	1:10 PM	San Diego	Seaport Village	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$215	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 10/29/2026 1:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 10/31/2026 6:40:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 52h 30m
Greyhound US	53h 55m	11:45 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$216	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 10/29/2026 11:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 10/31/2026 6:40:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 53h 55m
FlixBus	92h 55m	10:35 PM	San Diego	Old Town Transit Center	8:30 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$230	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 10/29/2026 10:35:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/2/2026 8:30:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 92h 55m
Greyhound US	61h 20m	7:45 PM	San Diego	Old Town Transit Center	10:05 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$244	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 10/29/2026 7:45:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/1/2026 10:05:00 AM. 50 Economy ticket for $244 per person are available. Travel duration is 61h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	56h 15m	9:25 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$212	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 10/30/2026 9:25:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/1/2026 6:40:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 56h 15m
FlixBus	52h 30m	1:10 PM	San Diego	Seaport Village	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$214	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 10/30/2026 1:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/1/2026 6:40:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 52h 30m
Greyhound US	53h 55m	11:45 AM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$214	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 10/30/2026 11:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/1/2026 6:40:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 53h 55m
Greyhound US	61h 20m	7:45 PM	San Diego	Old Town Transit Center	10:05 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$249	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 10/30/2026 7:45:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/2/2026 10:05:00 AM. 50 Economy ticket for $249 per person are available. Travel duration is 61h 20m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	54h 45m	11:45 AM	San Diego	Old Town Transit Center	8:30 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$209	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 11/2/2026 11:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/4/2026 8:30:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 54h 45m
FlixBus	53h 20m	1:10 PM	San Diego	Seaport Village	8:30 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$210	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 11/2/2026 1:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/4/2026 8:30:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 53h 20m
FlixBus	57h 5m	9:25 AM	San Diego	Old Town Transit Center	8:30 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$211	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 11/2/2026 9:25:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/4/2026 8:30:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 57h 5m
FlixBus	91h 55m	10:35 PM	San Diego	Old Town Transit Center	8:30 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$222	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 11/2/2026 10:35:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/6/2026 8:30:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 91h 55m
Greyhound US	68h 55m	7:45 PM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$224	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 11/2/2026 7:45:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 11/5/2026 6:40:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 68h 55m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	52h 55m	1:35 PM	San Diego	La Jolla Village	8:30 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$212	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 11/4/2026 1:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 11/6/2026 8:30:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 52h 55m
Greyhound US	54h 45m	11:45 AM	San Diego	Old Town Transit Center	8:30 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$212	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 11/4/2026 11:45:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 11/6/2026 8:30:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 54h 45m
FlixBus	53h 20m	1:10 PM	San Diego	Seaport Village	8:30 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$213	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 11/4/2026 1:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 11/6/2026 8:30:00 PM. 50 Economy ticket for $213 per person are available. Travel duration is 53h 20m
FlixBus	57h 5m	9:25 AM	San Diego	Old Town Transit Center	8:30 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$214	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 11/4/2026 9:25:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 11/6/2026 8:30:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 57h 5m
Greyhound US	60h 20m	7:45 PM	San Diego	Old Town Transit Center	10:05 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$222	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 11/4/2026 7:45:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 11/7/2026 10:05:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 60h 20m

Did you know that if you travel from San Diego to Santiago de Queretaro via Tijuana, BC, you can save more than $21? You can find the corresponding connections below.
- Greyhound US
  
  43h 56m
  
  0
  
  7:15 PM
  
  San Diego
  San Ysidro Transit Center
  
  8:35 PM
  
  Tijuana, BC
  Tijuana(Hotel City Express) Bus Station
  
  0
  
  Economy
  
  $4
  
  A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 11/2/2026 7:15:00 PM to Tijuana(Hotel City Express) Bus Station, Tijuana, BC (Mexico) arriving at 11/2/2026 8:35:00 PM. 50 Economy ticket for $4 per person are available. Travel duration is 1h 20m
- Elite Select
  
  39h 40m
  
  0
  
  11:31 PM
  
  Tijuana, BC
  Centro Bus Stop
  
  5:11 PM
  
  Santiago de Queretaro
  Terminal Norte
  
  0
  
  Economy
  
  $186
  
  A Bus from Elite Select goes from Centro Bus Stop, Tijuana, BC (Mexico) at 11/2/2026 11:31:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 11/4/2026 5:11:00 PM. 50 Economy ticket for $186 per person are available. Travel duration is 39h 40m
Travel Time is 10h 59m shorter, and you will save $21

Best Price Offer: The price for the cheapest bus from San Diego to Santiago de Queretaro is $207 on 11/12/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Diego and Santiago de Queretaro

See here how frequent the connections between San Diego and Santiago de Queretaro are, during different times and days of the week.

Wednesday is the busiest day, with more than 8 daily buses from San Diego to Santiago de Queretaro. Friday has instead the fewest connections, with only 4 daily coaches between San Diego and Santiago de Queretaro.

The busiest time of the day is the Evening, with 12 buses from San Diego to Santiago de Queretaro, while Afternoon sees the fewest connections between San Diego and Santiago de Queretaro, with 6 offers.

Facts about the bus from San Diego to Santiago de Queretaro

Compare all providers like FlixBus and Greyhound US that travel 6 times every day by bus from San Diego to Santiago de Queretaro in one click! Book your bus ticket from San Diego to Santiago de Queretaro starting from $207!

Cheapest Bus	$207
Fastest Bus	53h 30m
Earliest Bus	9:25 AM
Latest Bus	10:55 PM
Daily Bus Routes	6 Ø
Distance	1,331.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from San Diego to Santiago de Queretaro

Every day, 6 buses from 2 bus companies leave San Diego for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/29/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/25

Monday 10/26

Tuesday 10/27

Wednesday 10/28

Thursday 10/29

$261

Friday 10/30

$212

Saturday 10/31

$218

Sunday 11/01

Monday 11/02

$209

Tuesday 11/03

Wednesday 11/04

$212

Thursday 11/05

$214

Friday 11/06

$208

Saturday 11/07

$214

Sunday 11/08

$212

Monday 11/09

$208

Tuesday 11/10

$208

Wednesday 11/11

$208

Thursday 11/12

$207

Friday 11/13

Saturday 11/14

$207

Sunday 11/15

$208

Monday 11/16

$213

Tuesday 11/17

$209

Wednesday 11/18

$209

Thursday 11/19

Friday 11/20

$208

Saturday 11/21

The cheapest time to travel from San Diego to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Santiago de Queretaro, for the next 30 days.

With a price starting from $207, Monday is the cheapest day for a bus from San Diego to Santiago de Queretaro. Wednesday instead is the most expensive day with prices starting from $208.

Morning is the cheapest day time for bus tickets from San Diego to Santiago de Queretaro, with $209. Evening is the most expensive time of the day with prices starting from $222.

How to save money travelling from San Diego to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Santiago de Queretaro are also emptier.

All bus stations and stops in San Diego and Santiago de Queretaro

In the map below, you can see where to find all bus stations in San Diego and Santiago de Queretaro.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Seaport Village

W Harbor Dr 789

Santa Fe Depot

Kettner Blvd 1050

Downtown

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

Walmart Juriquilla

El Colorado

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Diego to Santiago de Queretaro? Compare all modes of transports from San Diego to Santiago de Queretaro.

Service and Comfort on the bus from San Diego to Santiago de Queretaro

Want to know which seat classes are available on the buses from San Diego to Santiago de Queretaro? Or which bus companies serve the route San Diego to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the San Diego to Santiago de Queretaro bus

How much does a San Diego Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $207 and takes 56h 45m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from San Diego to Santiago de Queretaro?

This route is offered by 2 companies with a range of ticket prices between $207 and $265. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from San Diego to Santiago de Queretaro each day?

Every day, the San Diego to Santiago de Queretaro bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Santiago de Queretaro take?

The fastest bus from San Diego to Santiago de Queretaro is offered by FlixBus and takes 53h 30m. Bus tickets for this connection cost $215. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from San Diego starts at 9:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Santiago de Queretaro?

The latest bus trip departing from San Diego for Santiago de Queretaro starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Santiago de Queretaro route?

When traveling by bus from San Diego to Santiago de Queretaro, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Santiago de Queretaro?

You can check all the direct connections between San Diego and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Santiago de Queretaro on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to Santiago de Queretaro?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between San Diego and Santiago de Queretaro. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to Santiago de Queretaro?

Prices and availability for 6 trips between San Diego and Santiago de Queretaro change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to Santiago de Queretaro

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to San Diego and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!