Bus San Diego to Santiago de Queretaro

Compare all timetables for the bus from San Diego to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from San Diego to Santiago de Queretaro from various bus operators like FlixBus or Greyhound US for the next days.

today

$220

tomorrow

Wednesday

$219

Thursday

$218

Friday

Saturday

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	62h 45m	1:10 PM	San Diego	Seaport Village	5:55 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 1/19/2026 1:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/22/2026 5:55:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 62h 45m
Greyhound US	69h 5m	7:35 PM	San Diego	Old Town Transit Center	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$221	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 1/19/2026 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/22/2026 6:40:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 69h 5m
FlixBus	58h 25m	7:35 AM	San Diego	Old Town Transit Center	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$222	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 1/19/2026 7:35:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/21/2026 8:00:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 58h 25m
FlixBus	63h 40m	12:15 PM	San Diego	Old Town Transit Center	5:55 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$222	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 1/19/2026 12:15:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/22/2026 5:55:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 63h 40m
Greyhound US	56h 0m	10:00 AM	San Diego	Old Town Transit Center	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$222	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 1/19/2026 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/21/2026 8:00:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 56h 0m

Did you know that if you travel from San Diego to Santiago de Queretaro via Tijuana, BC, you can save more than $38? You can find the corresponding connections below.
- Busbud
  
  70h 25m
  
  0
  
  5:55 PM
  
  San Diego
  Old Town Transit Center
  
  8:05 PM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 1/20/2026 5:55:00 PM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 1/20/2026 8:05:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 10m
- Busbud
  
  38h 20m
  
  0
  
  2:00 AM
  
  Tijuana, BC
  Central Bus Station
  
  6:20 PM
  
  Santiago de Queretaro
  Bus Station
  
  0
  
  Economy
  
  $176
  
  A Bus from Busbud goes from Central Bus Station, Tijuana, BC (Mexico) at 1/22/2026 2:00:00 AM to Bus Station, Santiago de Queretaro (Mexico) arriving at 1/23/2026 6:20:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 38h 20m
Travel time is 12h 25m longer, but you will save $38

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	59h 5m	6:55 AM	San Diego	San Ysidro Transit Center	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$219	A Bus from FlixBus goes from San Ysidro Transit Center, San Diego (USA) at 1/21/2026 6:55:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/23/2026 8:00:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 59h 5m
FlixBus	59h 5m	1:15 PM	San Diego	San Ysidro Transit Center	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$219	A Bus from FlixBus goes from San Ysidro Transit Center, San Diego (USA) at 1/21/2026 1:15:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/24/2026 2:20:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 59h 5m
Greyhound US	60h 30m	7:00 PM	San Diego	San Ysidro Transit Center	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$230	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 1/21/2026 7:00:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/24/2026 9:30:00 AM. 50 Economy ticket for $230 per person are available. Travel duration is 60h 30m

Did you know that if you travel from San Diego to Santiago de Queretaro via Tijuana, BC, you can save more than $37? You can find the corresponding connections below.
- Busbud
  
  51h 49m
  
  0
  
  12:01 AM
  
  San Diego
  Old Town Transit Center
  
  2:25 AM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $6
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 1/22/2026 12:01:00 AM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 1/22/2026 2:25:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 2h 24m
- Busbud
  
  38h 20m
  
  0
  
  1:30 PM
  
  Tijuana, BC
  Central Bus Station
  
  5:50 AM
  
  Santiago de Queretaro
  Bus Station
  
  0
  
  Economy
  
  $176
  
  A Bus from Busbud goes from Central Bus Station, Tijuana, BC (Mexico) at 1/22/2026 1:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 1/24/2026 5:50:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 38h 20m
Travel Time is 9h 16m shorter, and you will save $37

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	58h 25m	7:35 AM	San Diego	Old Town Transit Center	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$218	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 1/22/2026 7:35:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/24/2026 8:00:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 58h 25m
FlixBus	59h 10m	1:10 PM	San Diego	Seaport Village	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$219	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 1/22/2026 1:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/25/2026 2:20:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 59h 10m
Greyhound US	56h 0m	10:00 AM	San Diego	Old Town Transit Center	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$219	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 1/22/2026 10:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/24/2026 8:00:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 56h 0m
FlixBus	62h 55m	9:25 AM	San Diego	Old Town Transit Center	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$220	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 1/22/2026 9:25:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/25/2026 2:20:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 62h 55m
Greyhound US	59h 55m	7:35 PM	San Diego	Old Town Transit Center	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$225	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 1/22/2026 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 1/25/2026 9:30:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 59h 55m

Did you know that if you travel from San Diego to Santiago de Queretaro via Tijuana, BC, you can save more than $36? You can find the corresponding connections below.
- Busbud
  
  51h 49m
  
  0
  
  12:01 AM
  
  San Diego
  Old Town Transit Center
  
  2:25 AM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $6
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 1/22/2026 12:01:00 AM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 1/22/2026 2:25:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 2h 24m
- Busbud
  
  38h 20m
  
  0
  
  1:30 PM
  
  Tijuana, BC
  Central Bus Station
  
  5:50 AM
  
  Santiago de Queretaro
  Bus Station
  
  0
  
  Economy
  
  $176
  
  A Bus from Busbud goes from Central Bus Station, Tijuana, BC (Mexico) at 1/22/2026 1:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 1/24/2026 5:50:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 38h 20m
Travel Time is 6h 11m shorter, and you will save $36

Best Price Offer: The price for the cheapest bus from San Diego to Santiago de Queretaro is $218 on 1/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Diego and Santiago de Queretaro

See here how frequent the connections between San Diego and Santiago de Queretaro are, during different times and days of the week.

Monday is the busiest day, with more than 10 daily buses from San Diego to Santiago de Queretaro. Wednesday has instead the fewest connections, with only 3 daily coaches between San Diego and Santiago de Queretaro.

The busiest time of the day is the Morning, with 8 buses from San Diego to Santiago de Queretaro, while Evening sees the fewest connections between San Diego and Santiago de Queretaro, with 4 offers.

Facts about the bus from San Diego to Santiago de Queretaro

Compare all providers like FlixBus and Greyhound US that travel 6 times every day by bus from San Diego to Santiago de Queretaro in one click! Book your bus ticket from San Diego to Santiago de Queretaro starting from $218!

Cheapest Bus	$218
Fastest Bus	58h 0m
Earliest Bus	7:35 AM
Latest Bus	7:35 PM
Daily Bus Routes	6 Ø
Distance	1,331.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from San Diego to Santiago de Queretaro

Every day, 6 buses from 2 bus companies leave San Diego for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$223

Tuesday 01/20

Wednesday 01/21

$219

Thursday 01/22

$218

Friday 01/23

Saturday 01/24

Sunday 01/25

Monday 01/26

Tuesday 01/27

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

$224

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from San Diego to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Santiago de Queretaro, for the next 30 days.

With a price starting from $218, Thursday is the cheapest day for a bus from San Diego to Santiago de Queretaro. Monday instead is the most expensive day with prices starting from $220.

Morning is the cheapest day time for bus tickets from San Diego to Santiago de Queretaro, with $218. Evening is the most expensive time of the day with prices starting from $221.

How to save money travelling from San Diego to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Santiago de Queretaro are also emptier.

Beloved bus companies from San Diego to Santiago de Queretaro

These are the most booked bus companies between San Diego to Santiago de Queretaro from our users.

Greyhound US from San Diego to Santiago de Queretaro

Here you will find the key facts about the Greyhound US bus route San Diego to Santiago de Queretaro:

Cheapest Price	$219
Fastest Bus	58h 0m
Earliest Bus	9:25 AM
Last Bus	7:35 PM
Daily Connections	2 Ø
Found on	1/14/2026

All bus stations and stops in San Diego and Santiago de Queretaro

In the map below, you can see where to find all bus stations in San Diego and Santiago de Queretaro.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

Service and Comfort on the bus from San Diego to Santiago de Queretaro

Want to know which seat classes are available on the buses from San Diego to Santiago de Queretaro? Or which bus companies serve the route San Diego to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the San Diego to Santiago de Queretaro bus

How much does a San Diego Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $218 and takes 60h 25m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from San Diego to Santiago de Queretaro?

This route is offered by 2 companies with a range of ticket prices between $218 and $230. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from San Diego to Santiago de Queretaro each day?

Every day, the San Diego to Santiago de Queretaro bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Santiago de Queretaro take?

The fastest bus from San Diego to Santiago de Queretaro is offered by Greyhound US and takes 58h 0m. Bus tickets for this connection cost $222. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from San Diego starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Santiago de Queretaro?

The latest bus trip departing from San Diego for Santiago de Queretaro starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Santiago de Queretaro route?

When traveling by bus from San Diego to Santiago de Queretaro, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Santiago de Queretaro?

You can check all the direct connections between San Diego and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Santiago de Queretaro on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to Santiago de Queretaro?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between San Diego and Santiago de Queretaro. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to Santiago de Queretaro?

Prices and availability for 6 trips between San Diego and Santiago de Queretaro change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to Santiago de Queretaro

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to San Diego and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!