Bus Cincinnati to San Diego - Compare all Companies

Compare all timetables for the bus from Cincinnati to San Diego

Here is a selection of the cheapest bus trips from the schedule from Cincinnati to San Diego from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Thursday

$181

Friday

$219

Saturday

$206

Sunday

$219

Monday

$191

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	59h 55m	7:00 AM	Cincinnati	University of Cincinnati	3:55 PM	San Diego	La Jolla Village	Economy	$181	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/3/2026 7:00:00 AM to La Jolla Village, San Diego (USA) arriving at 9/5/2026 3:55:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 59h 55m
FlixBus	59h 40m	7:15 AM	Cincinnati	Downtown	3:55 PM	San Diego	La Jolla Village	Economy	$181	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 9/3/2026 7:15:00 AM to La Jolla Village, San Diego (USA) arriving at 9/5/2026 3:55:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 59h 40m
FlixBus	60h 25m	7:00 AM	Cincinnati	University of Cincinnati	4:25 PM	San Diego	Old Town Transit Center	Economy	$183	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/3/2026 7:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/5/2026 4:25:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 60h 25m
Greyhound US	58h 40m	10:05 AM	Cincinnati	Greyhound Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$198	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/3/2026 10:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/5/2026 5:45:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 58h 40m
Greyhound US	61h 50m	12:55 AM	Cincinnati	Greyhound Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$201	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/3/2026 12:55:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/5/2026 11:45:00 AM. 50 Economy ticket for $201 per person are available. Travel duration is 61h 50m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	62h 20m	7:00 AM	Cincinnati	University of Cincinnati	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$219	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/4/2026 7:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/6/2026 6:20:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 62h 20m
FlixBus	62h 5m	7:15 AM	Cincinnati	Downtown	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$219	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 9/4/2026 7:15:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/6/2026 6:20:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 62h 5m
FlixBus	61h 10m	7:00 AM	Cincinnati	University of Cincinnati	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$223	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/4/2026 7:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/6/2026 5:10:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 61h 10m
Greyhound US	62h 25m	12:55 AM	Cincinnati	Greyhound Bus Station	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$272	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/4/2026 12:55:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/6/2026 12:20:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 62h 25m
Greyhound US	68h 25m	12:55 AM	Cincinnati	Greyhound Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$272	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/4/2026 12:55:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/6/2026 6:20:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 68h 25m

Did you know that if you travel from Cincinnati to San Diego via Indianapolis, you can save more than $24? You can find the corresponding connections below.
- FlixBus
  
  62h 5m
  
  0
  
  7:15 AM
  
  Cincinnati
  Downtown
  
  9:15 AM
  
  Indianapolis
  Washington / Delaware
  
  0
  
  Economy
  
  $23
  
  A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 9/5/2026 7:15:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 9/5/2026 9:15:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 0m
- Greyhound US
  
  58h 15m
  
  0
  
  11:05 AM
  
  Indianapolis
  Central Bus Station
  
  6:20 PM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $172
  
  A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 9/5/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/7/2026 6:20:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 58h 15m
Travel time is 3h 55m longer, but you will save $24

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	76h 25m	3:00 PM	Cincinnati	University of Cincinnati	4:25 PM	San Diego	Old Town Transit Center	Economy	$206	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/5/2026 3:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/8/2026 4:25:00 PM. 50 Economy ticket for $206 per person are available. Travel duration is 76h 25m
FlixBus	60h 25m	7:00 AM	Cincinnati	University of Cincinnati	4:25 PM	San Diego	Old Town Transit Center	Economy	$209	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/5/2026 7:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 4:25:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 60h 25m
FlixBus	60h 10m	7:15 AM	Cincinnati	Downtown	4:25 PM	San Diego	Old Town Transit Center	Economy	$209	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 9/5/2026 7:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 4:25:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 60h 10m
Greyhound US	66h 30m	12:55 AM	Cincinnati	Greyhound Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$211	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/5/2026 12:55:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 4:25:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 66h 30m
Greyhound US	63h 10m	10:05 AM	Cincinnati	Greyhound Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$231	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/5/2026 10:05:00 AM to Seaport Village, San Diego (USA) arriving at 9/7/2026 10:15:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 63h 10m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	62h 20m	7:00 AM	Cincinnati	University of Cincinnati	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$219	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/6/2026 7:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/8/2026 6:20:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 62h 20m
FlixBus	62h 5m	7:15 AM	Cincinnati	Downtown	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$219	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 9/6/2026 7:15:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/8/2026 6:20:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 62h 5m
FlixBus	61h 10m	7:00 AM	Cincinnati	University of Cincinnati	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$224	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/6/2026 7:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/8/2026 5:10:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 61h 10m
Greyhound US	62h 25m	12:55 AM	Cincinnati	Greyhound Bus Station	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$237	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/6/2026 12:55:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/8/2026 12:20:00 PM. 50 Economy ticket for $237 per person are available. Travel duration is 62h 25m
Greyhound US	68h 25m	12:55 AM	Cincinnati	Greyhound Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$238	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/6/2026 12:55:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/8/2026 6:20:00 PM. 50 Economy ticket for $238 per person are available. Travel duration is 68h 25m

Did you know that if you travel from Cincinnati to San Diego via Indianapolis, you can save more than $34? You can find the corresponding connections below.
- FlixBus
  
  84h 55m
  
  0
  
  7:15 AM
  
  Cincinnati
  Downtown
  
  9:15 AM
  
  Indianapolis
  Washington / Delaware
  
  0
  
  Economy
  
  $23
  
  A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 9/6/2026 7:15:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 9/6/2026 9:15:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 0m
- FlixBus
  
  58h 40m
  
  0
  
  9:30 AM
  
  Indianapolis
  Washington / Delaware
  
  5:10 PM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $162
  
  A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 9/7/2026 9:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/9/2026 5:10:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 58h 40m
Travel time is 26h 45m longer, but you will save $34

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	59h 55m	7:00 AM	Cincinnati	University of Cincinnati	3:55 PM	San Diego	La Jolla Village	Economy	$191	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/7/2026 7:00:00 AM to La Jolla Village, San Diego (USA) arriving at 9/9/2026 3:55:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 59h 55m
FlixBus	59h 40m	7:15 AM	Cincinnati	Downtown	3:55 PM	San Diego	La Jolla Village	Economy	$191	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 9/7/2026 7:15:00 AM to La Jolla Village, San Diego (USA) arriving at 9/9/2026 3:55:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 59h 40m
FlixBus	60h 25m	7:00 AM	Cincinnati	University of Cincinnati	4:25 PM	San Diego	Old Town Transit Center	Economy	$192	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 9/7/2026 7:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/9/2026 4:25:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 60h 25m
Greyhound US	58h 40m	10:05 AM	Cincinnati	Greyhound Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$203	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/7/2026 10:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/9/2026 5:45:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 58h 40m
Greyhound US	63h 10m	10:05 AM	Cincinnati	Greyhound Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$205	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 9/7/2026 10:05:00 AM to Seaport Village, San Diego (USA) arriving at 9/9/2026 10:15:00 PM. 50 Economy ticket for $205 per person are available. Travel duration is 63h 10m

Best Price Offer: The price for the cheapest bus from Cincinnati to San Diego is $149 on 9/13/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Cincinnati and San Diego

See here how frequent the connections between Cincinnati and San Diego are, during different times and days of the week.

Thursday is the busiest day, with more than 27 daily buses from Cincinnati to San Diego. Sunday has instead the fewest connections, with only 9 daily coaches between Cincinnati and San Diego.

The busiest time of the day is the Morning, with 38 buses from Cincinnati to San Diego, while Night sees the fewest connections between Cincinnati and San Diego, with 15 offers.

Facts about the bus from Cincinnati to San Diego

Compare all providers like FlixBus and Greyhound US that travel 16 times every day by bus from Cincinnati to San Diego in one click! Book your bus ticket from Cincinnati to San Diego starting from $149!

Cheapest Bus	$149
Fastest Bus	50h 45m
Earliest Bus	12:55 AM
Latest Bus	3:00 PM
Daily Bus Routes	16 Ø
Distance	1,867.9 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Cincinnati to San Diego

Every day, 16 buses from 2 bus companies leave Cincinnati for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/01/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/30

Monday 08/31

Tuesday 09/01

Wednesday 09/02

Thursday 09/03

$231

Friday 09/04

$219

Saturday 09/05

$223

Sunday 09/06

$219

Monday 09/07

$191

Tuesday 09/08

$218

Wednesday 09/09

$219

Thursday 09/10

$160

Friday 09/11

Saturday 09/12

Sunday 09/13

$149

Monday 09/14

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

$170

Friday 09/18

Saturday 09/19

$223

Sunday 09/20

$201

Monday 09/21

$170

Tuesday 09/22

Wednesday 09/23

$164

Thursday 09/24

$226

Friday 09/25

$226

Saturday 09/26

The cheapest time to travel from Cincinnati to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Cincinnati to San Diego, for the next 30 days.

With a price starting from $149, Sunday is the cheapest day for a bus from Cincinnati to San Diego. Friday instead is the most expensive day with prices starting from $219.

Night is the cheapest day time for bus tickets from Cincinnati to San Diego, with $149. Afternoon is the most expensive time of the day with prices starting from $195.

How to save money travelling from Cincinnati to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cincinnati to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cincinnati to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cincinnati to San Diego are also emptier.

Beloved bus companies from Cincinnati to San Diego

These are the most booked bus companies between Cincinnati to San Diego from our users.

FlixBus from Cincinnati to San Diego

Here you will find the key facts about the FlixBus bus route Cincinnati to San Diego:

Cheapest Price	$181
Fastest Bus	50h 45m
Earliest Bus	7:00 AM
Last Bus	3:00 PM
Daily Connections	11 Ø
Found on	8/8/2026

All bus stations and stops in Cincinnati and San Diego

In the map below, you can see where to find all bus stations in Cincinnati and San Diego.

University of Cincinnati

Commons Way 2815

Greyhound Bus Station

Gilbert Ave 1005

E Galbraith Rd

Downtown

E Court St 419

Hughes STEM High School

2515 Clifton Ave

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

Downtown

Service and Comfort on the bus from Cincinnati to San Diego

Want to know which seat classes are available on the buses from Cincinnati to San Diego? Or which bus companies serve the route Cincinnati to San Diego? Below you will find answers to your questions.

FAQs about the Cincinnati to San Diego bus

How much does a Cincinnati San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $149 and takes 56h 55m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Cincinnati to San Diego?

This route is offered by 2 companies with a range of ticket prices between $149 and $291. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Cincinnati to San Diego each day?

Every day, the Cincinnati to San Diego bus route is served by approximately 16 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cincinnati to San Diego take?

The fastest bus from Cincinnati to San Diego is offered by FlixBus and takes 50h 45m. Bus tickets for this connection cost $206. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cincinnati to San Diego?

The earliest bus arriving in San Diego from Cincinnati starts at 12:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cincinnati to San Diego?

The latest bus trip departing from Cincinnati for San Diego starts at 3:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cincinnati San Diego route?

When traveling by bus from Cincinnati to San Diego, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cincinnati and San Diego?

You can check all the direct connections between Cincinnati and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Cincinnati to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cincinnati San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cincinnati San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cincinnati to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Cincinnati to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 16 daily trips between Cincinnati and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Cincinnati to San Diego?

Prices and availability for 16 trips between Cincinnati and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Cincinnati to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cincinnati and to San Diego

Here’s an overview of the most popular bus routes to Cincinnati and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!