What is the best way to travel from Mississauga, ON to Chicago?
Looking for a trip? Compare all the available Buses and Flights for the journey to Chicago from Mississauga, ON. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from Mississauga, ON?
You can get to Chicago with just $65 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
FlixBus17h 50m012:45 PMPearson Toronto AirportPearson Toronto Airport5:35 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/4/2025 12:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/5/2025 5:35:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 17h 50m
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/4/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/5/2025 11:25:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 50m
-
FlixBus12h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/4/2025 11:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/5/2025 11:25:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 30m
-
FlixBus14h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/4/2025 11:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/5/2025 1:25:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 30m
-
FlixBus14h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/4/2025 11:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/5/2025 1:25:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 50m
Cheapest Buses Thursday
-
FlixBus17h 50m012:45 PMPearson Toronto AirportPearson Toronto Airport5:35 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/5/2025 12:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 5:35:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 17h 50m
-
FlixBus20h 35m012:45 PMPearson Toronto AirportPearson Toronto Airport8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/5/2025 12:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/6/2025 8:20:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 20h 35m
-
FlixBus14h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/5/2025 11:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/6/2025 1:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 50m
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/5/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 11:25:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 12h 50m
-
FlixBus14h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/5/2025 11:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/6/2025 1:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 30m
Cheapest Buses Friday
-
FlixBus23h 0m02:35 AMPearson Toronto AirportPearson Toronto Airport12:35 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 2:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 12:35:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 23h 0m
-
FlixBus20h 35m012:45 PMPearson Toronto AirportPearson Toronto Airport8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 12:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 8:20:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 20h 35m
-
FlixBus14h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 11:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 1:25:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 14h 50m
-
FlixBus14h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/6/2025 11:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 1:25:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 14h 30m
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/7/2025 11:25:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 12h 50m
Cheapest Buses Saturday
-
FlixBus17h 50m012:45 PMPearson Toronto AirportPearson Toronto Airport5:35 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/7/2025 12:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/8/2025 5:35:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 17h 50m
-
FlixBus19h 50m02:35 AMPearson Toronto AirportPearson Toronto Airport9:25 PMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/7/2025 2:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/7/2025 9:25:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 19h 50m
-
FlixBus12h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/7/2025 11:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/8/2025 11:25:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 30m
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/7/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/8/2025 11:25:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 50m
Cheapest Buses Sunday
-
FlixBus19h 50m02:35 AMPearson Toronto AirportPearson Toronto Airport9:25 PMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/8/2025 2:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/8/2025 9:25:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 19h 50m
-
FlixBus12h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/8/2025 11:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/9/2025 11:25:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 12h 30m
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/8/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/9/2025 11:25:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 12h 50m
-
FlixBus14h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/8/2025 11:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 1:25:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 14h 50m
-
FlixBus14h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/8/2025 11:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 1:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 30m
Cheapest Buses Monday
-
FlixBus20h 0m010:35 AMPearson Toronto AirportPearson Toronto Airport5:35 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/10/2025 10:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/11/2025 5:35:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 20h 0m
-
FlixBus22h 45m010:35 AMPearson Toronto AirportPearson Toronto Airport8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/10/2025 10:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/11/2025 8:20:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 22h 45m
Cheapest Buses Wednesday
What are the fastest trips from Mississauga, ON to Chicago?
You can get to Chicago from Mississauga, ON in just 12h 30m with a Bus from FlixBus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
FlixBus12h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/4/2025 11:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/5/2025 11:25:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 30m
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/4/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/5/2025 11:25:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 50m
-
FlixBus14h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/4/2025 11:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/5/2025 1:25:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 30m
-
FlixBus14h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/4/2025 11:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/5/2025 1:25:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 50m
-
FlixBus17h 50m012:45 PMPearson Toronto AirportPearson Toronto Airport5:35 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/4/2025 12:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/5/2025 5:35:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 17h 50m
Fastest Buses Thursday
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/5/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 11:25:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 12h 50m
-
FlixBus14h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/5/2025 11:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/6/2025 1:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 30m
-
FlixBus14h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/5/2025 11:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/6/2025 1:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 50m
-
FlixBus17h 50m012:45 PMPearson Toronto AirportPearson Toronto Airport5:35 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/5/2025 12:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 5:35:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 17h 50m
-
FlixBus20h 35m012:45 PMPearson Toronto AirportPearson Toronto Airport8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/5/2025 12:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/6/2025 8:20:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 20h 35m
Fastest Buses Friday
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/7/2025 11:25:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 12h 50m
-
FlixBus14h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/6/2025 11:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 1:25:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 14h 30m
-
FlixBus14h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 11:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 1:25:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 14h 50m
-
FlixBus20h 35m012:45 PMPearson Toronto AirportPearson Toronto Airport8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 12:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 8:20:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 20h 35m
-
FlixBus23h 0m02:35 AMPearson Toronto AirportPearson Toronto Airport12:35 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 2:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 12:35:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 23h 0m
Fastest Buses Saturday
-
FlixBus12h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/7/2025 11:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/8/2025 11:25:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 30m
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/7/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/8/2025 11:25:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 50m
-
FlixBus17h 50m012:45 PMPearson Toronto AirportPearson Toronto Airport5:35 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/7/2025 12:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/8/2025 5:35:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 17h 50m
-
FlixBus19h 50m02:35 AMPearson Toronto AirportPearson Toronto Airport9:25 PMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/7/2025 2:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/7/2025 9:25:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 19h 50m
Fastest Buses Sunday
-
FlixBus12h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/8/2025 11:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/9/2025 11:25:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 12h 30m
-
FlixBus12h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport11:25 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/8/2025 11:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/9/2025 11:25:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 12h 50m
-
FlixBus14h 30m011:55 PMMississauga, ONCity Centre Dr / Duke of York Blvd1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 12/8/2025 11:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 1:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 30m
-
FlixBus14h 50m011:35 PMPearson Toronto AirportPearson Toronto Airport1:25 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/8/2025 11:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 1:25:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 14h 50m
-
FlixBus19h 50m02:35 AMPearson Toronto AirportPearson Toronto Airport9:25 PMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/8/2025 2:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/8/2025 9:25:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 19h 50m
Fastest Buses Monday
-
FlixBus20h 0m010:35 AMPearson Toronto AirportPearson Toronto Airport5:35 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/10/2025 10:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/11/2025 5:35:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 20h 0m
-
FlixBus22h 45m010:35 AMPearson Toronto AirportPearson Toronto Airport8:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/10/2025 10:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/11/2025 8:20:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 22h 45m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Mississauga, ON to Chicago
What are the most popular stations in Mississauga, ON and Chicago?
In Mississauga, ON, you will usually depart from City Centre Dr / Duke of York Blvd, Winston Churchill Bus Station or Mavis Rd At Cantay Rd Bus Stop, while in Chicago you will be arriving at California & 35th Street Bus Stop, Downtown Bus Station or 95th Red Line Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from Mississauga, ON? With 4 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mississauga, ON and Chicago, you can pay as low as $65 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Chicago in just 12h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mississauga, ON and Chicago are FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mississauga, ON and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Pearson Toronto Airport or to Cicero, IL, and look at flights from Pearson Toronto Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mississauga, ON to Chicago?
The most popular companies between Mississauga, ON and Chicago, are FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
All you need to know when you travel from Mississauga, ON to Chicago
Check all information on comfort and services on all modes of transports from Mississauga, ON to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mississauga, ON to Chicago
How can I reach Chicago from Mississauga, ON?
Every day, there are on average 4 connections between Bus and Flight, with which you can get to Chicago from Mississauga, ON.
How far is Chicago from Mississauga, ON?
The distance between Mississauga, ON and Chicago is 422.6 miles.
What is the most ecofriendly mode of transport between Mississauga, ON and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 18 kgs of CO2, a train 24 kgs, a car 116 kgs, and a flight 167 kgs.
What is the cheapest mode of transport from Mississauga, ON to Chicago?
You can get to Chicago with just $65 by taking a Bus from FlixBus.
What is the fastest way to get from Mississauga, ON to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 12h 30m with a Bus from FlixBus.
More routes to Mississauga, ON and to Chicago
Looking for more options? Here you can see the most popular routes to Mississauga, ON and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mississauga, ON
- New York to Mississauga, ON
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Bloomington, IN to Chicago
- Buffalo, NY to Chicago
- Dallas to Chicago
- El Paso, TX to Chicago
- Guadalajara, JC to Chicago
- Houston to Chicago
- Louisville, KY to Chicago
- McAllen, TX to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Monterrey, NL to Chicago
- Nashville to Chicago
- New York to Chicago
- Pearson Toronto Airport to Chicago
- Philadelphia to Chicago
- San Antonio, TX to Chicago
- San Diego to Chicago
- San Luis Potosí to Chicago
- St. Louis, MO to Chicago
- Toronto, ON to Chicago
- Tulsa to Chicago

