Bus from Mississauga, ON to Chicago from $58

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Mississauga, ON to Chicago

Here is a selection of the cheapest bus trips from the schedule from Mississauga, ON to Chicago from various bus operators like FlixBus for the next days.

today
$60
tomorrow
$58
Wednesday
$63
Thursday
$72
Friday
$79
Saturday
$65
Sunday
$75

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 20m 8:00 AM Mississauga, ON City Centre Dr / Duke of York Blvd 10:20 AM Chicago 95th Red Line Station  Economy $60
FlixBus 14h 30m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 1:25 PM Chicago 95th Red Line Station  Economy $61
FlixBus 12h 25m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 11:20 AM Chicago Downtown Bus Station  Economy $72
FlixBus 22h 25m 8:00 AM Mississauga, ON City Centre Dr / Duke of York Blvd 5:25 AM Chicago Downtown Bus Station  Economy $75
FlixBus 18h 5m 4:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 10:00 AM Chicago Downtown Bus Station  Economy $75

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 35m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 4:30 PM Chicago 95th Red Line Station  Economy $58
FlixBus 18h 10m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 5:05 PM Chicago Downtown Bus Station  Economy $65
FlixBus 18h 40m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 5:35 PM Chicago Downtown Bus Station  Economy $65
FlixBus 18h 5m 4:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 10:00 AM Chicago Downtown Bus Station  Economy $68
FlixBus 27h 20m 8:00 AM Mississauga, ON City Centre Dr / Duke of York Blvd 10:20 AM Chicago 95th Red Line Station  Economy $68

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 5m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 11:30 PM Chicago 95th Red Line Station  Economy $63
FlixBus 27h 20m 8:00 AM Mississauga, ON City Centre Dr / Duke of York Blvd 10:20 AM Chicago 95th Red Line Station  Economy $63
FlixBus 17h 35m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 4:30 PM Chicago 95th Red Line Station  Economy $69
FlixBus 14h 30m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 1:25 PM Chicago Downtown Bus Station  Economy $73
FlixBus 17h 0m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 9:25 PM Chicago Downtown Bus Station  Economy $75
  • Did you know that if you travel from Mississauga, ON to Chicago via London, ON, you can save more than $7? You can find the corresponding connections below.
    • Rider Express
      16h 5m
      0
      8:30 AM
      Mississauga, ON
      Mavis Rd At Cantay Rd Bus Stop
      10:15 AM
      London, ON
      205 York St Bus Station
      0
      Rider Express
      Economy
      $17
      • Waiting Time 0h 40m
    • FlixBus
      13h 40m
      0
      10:55 AM
      London, ON
      Central Bus Station
      11:35 PM
      Chicago
      95th Red Line Station
      0
      FlixBus
      Economy
      $40
    Travel time is 2h 35m longer, but you will save $7

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 5m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 11:30 PM Chicago 95th Red Line Station  Economy $72
FlixBus 14h 30m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 1:25 PM Chicago 95th Red Line Station  Economy $79
FlixBus 17h 0m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 9:25 PM Chicago Downtown Bus Station  Economy $82
FlixBus 12h 20m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 11:15 AM Chicago Downtown Bus Station  Economy $88
FlixBus 18h 5m 4:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 10:00 AM Chicago Downtown Bus Station  Economy $97
  • Did you know that if you travel from Mississauga, ON to Chicago via London, ON, you can save more than $16? You can find the corresponding connections below.
    • Rider Express
      16h 5m
      0
      8:30 AM
      Mississauga, ON
      Mavis Rd At Cantay Rd Bus Stop
      10:15 AM
      London, ON
      205 York St Bus Station
      0
      Rider Express
      Economy
      $17
      • Waiting Time 0h 40m
    • FlixBus
      13h 40m
      0
      10:55 AM
      London, ON
      Central Bus Station
      11:35 PM
      Chicago
      95th Red Line Station
      0
      FlixBus
      Economy
      $40
    Travel time is 4h 45m longer, but you will save $16

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 30m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 1:25 PM Chicago 95th Red Line Station  Economy $79
FlixBus 12h 20m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 11:15 AM Chicago Downtown Bus Station  Economy $85
FlixBus 19h 5m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 11:30 PM Chicago 95th Red Line Station  Economy $106
FlixBus 27h 20m 8:00 AM Mississauga, ON City Centre Dr / Duke of York Blvd 10:20 AM Chicago 95th Red Line Station  Economy $115
FlixBus 17h 0m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 9:25 PM Chicago Downtown Bus Station  Economy $124
  • Did you know that if you travel from Mississauga, ON to Chicago via London, ON, you can save more than $23? You can find the corresponding connections below.
    • Rider Express
      16h 5m
      0
      8:30 AM
      Mississauga, ON
      Mavis Rd At Cantay Rd Bus Stop
      10:15 AM
      London, ON
      205 York St Bus Station
      0
      Rider Express
      Economy
      $17
      • Waiting Time 0h 40m
    • FlixBus
      13h 40m
      0
      10:55 AM
      London, ON
      Central Bus Station
      11:35 PM
      Chicago
      95th Red Line Station
      0
      FlixBus
      Economy
      $40
    Travel time is 4h 45m longer, but you will save $23

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 30m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 1:25 PM Chicago 95th Red Line Station  Economy $65
FlixBus 26h 50m 8:00 AM Mississauga, ON City Centre Dr / Duke of York Blvd 9:50 AM Chicago 95th Red Line Station  Economy $66
FlixBus 19h 5m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 11:30 PM Chicago 95th Red Line Station  Economy $76
FlixBus 12h 20m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 11:15 AM Chicago Downtown Bus Station  Economy $86
FlixBus 22h 25m 8:00 AM Mississauga, ON City Centre Dr / Duke of York Blvd 5:25 AM Chicago Downtown Bus Station  Economy $88
  • Did you know that if you travel from Mississauga, ON to Chicago via London, ON, you can save more than $9? You can find the corresponding connections below.
    • ONEXBUS
      13h 37m
      0
      10:38 PM
      Mississauga, ON
      Mavis Rd At Cantay Rd Bus Stop
      12:10 AM
      London, ON
      Wellington Road
      0
      ONEXBUS
      Economy
      $14
      • Waiting Time 2h 0m
    • FlixBus
      10h 5m
      0
      2:10 AM
      London, ON
      Central Bus Station
      11:15 AM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $41
    Travel time is 2h 17m longer, but you will save $9

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 5m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 11:30 PM Chicago 95th Red Line Station  Economy $75
FlixBus 14h 30m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 1:25 PM Chicago 95th Red Line Station  Economy $76
FlixBus 26h 50m 8:00 AM Mississauga, ON City Centre Dr / Duke of York Blvd 9:50 AM Chicago 95th Red Line Station  Economy $81
FlixBus 17h 0m 5:25 AM Mississauga, ON City Centre Dr / Duke of York Blvd 9:25 PM Chicago Downtown Bus Station  Economy $92
FlixBus 12h 20m 11:55 PM Mississauga, ON City Centre Dr / Duke of York Blvd 11:15 AM Chicago Downtown Bus Station  Economy $92
  • Did you know that if you travel from Mississauga, ON to Chicago via London, ON, you can save more than $19? You can find the corresponding connections below.
    • ONEXBUS
      13h 37m
      0
      10:38 PM
      Mississauga, ON
      Mavis Rd At Cantay Rd Bus Stop
      12:10 AM
      London, ON
      Wellington Road
      0
      ONEXBUS
      Economy
      $14
      • Waiting Time 2h 0m
    • FlixBus
      10h 5m
      0
      2:10 AM
      London, ON
      Central Bus Station
      11:15 AM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $41
    Travel time is 2h 17m longer, but you will save $19

Best Price Offer: The price for the cheapest bus from Mississauga, ON to Chicago is $58 on 9/22/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Mississauga, ON and Chicago

See here how frequent the connections between Mississauga, ON and Chicago are, during different times and days of the week.
Sunday is the busiest day, with more than 9 daily buses from Mississauga, ON to Chicago. Thursday has instead the fewest connections, with only 7 daily coaches between Mississauga, ON and Chicago.
The busiest time of the day is the Evening, with 25 buses from Mississauga, ON to Chicago, while Afternoon sees the fewest connections between Mississauga, ON and Chicago, with 6 offers.

Facts about the bus from Mississauga, ON to Chicago

Compare all providers like FlixBus that travel 8 times every day by bus from Mississauga, ON to Chicago in one click! Book your bus ticket from Mississauga, ON to Chicago starting from $58!

Cheapest Bus $58
Fastest Bus 11h 20m
Earliest Bus 5:25 AM
Latest Bus 11:55 PM
Daily Bus Routes 8 Ø
Distance 422.6 miles
Bus Companies FlixBus

Cheapest bus connections from Mississauga, ON to Chicago

Every day, 8 buses from 1 bus companies leave Mississauga, ON for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/21/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 09/20
Monday 09/21
$60
Tuesday 09/22
$58
Wednesday 09/23
$63
Thursday 09/24
$72
Friday 09/25
$85
Saturday 09/26
$65
Sunday 09/27
$75
Monday 09/28
$73
Tuesday 09/29
$69
Wednesday 09/30
$63
Thursday 10/01
$85
Friday 10/02
$77
Saturday 10/03
$66
Sunday 10/04
$70
Monday 10/05
$64
Tuesday 10/06
$62
Wednesday 10/07
$61
Thursday 10/08
$100
Friday 10/09
$101
Saturday 10/10
$84
Sunday 10/11
$83
Monday 10/12
$91
Tuesday 10/13
$77
Wednesday 10/14
$68
Thursday 10/15
$67
Friday 10/16
$64
Saturday 10/17

The cheapest time to travel from Mississauga, ON to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Mississauga, ON to Chicago, for the next 30 days.
With a price starting from $58, Tuesday is the cheapest day for a bus from Mississauga, ON to Chicago. Sunday instead is the most expensive day with prices starting from $70.
Evening is the cheapest day time for bus tickets from Mississauga, ON to Chicago, with $58. Afternoon is the most expensive time of the day with prices starting from $68.

How to save money travelling from Mississauga, ON to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mississauga, ON to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mississauga, ON to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mississauga, ON to Chicago are also emptier.

Beloved bus companies from Mississauga, ON to Chicago

These are the most booked bus companies between Mississauga, ON to Chicago from our users.

FlixBus from Mississauga, ON to Chicago

FlixBus

Here you will find the key facts about the FlixBus bus route Mississauga, ON to Chicago:

Cheapest Price $58
Fastest Bus 11h 20m
Earliest Bus 5:25 AM
Last Bus 11:55 PM
Daily Connections 8 Ø
Found on 9/21/2026

All bus stations and stops in Mississauga, ON and Chicago

In the map below, you can see where to find all bus stations in Mississauga, ON and Chicago.

Service and Comfort on the bus from Mississauga, ON to Chicago

Want to know which seat classes are available on the buses from Mississauga, ON to Chicago? Or which bus companies serve the route Mississauga, ON to Chicago? Below you will find answers to your questions.

FAQs about the Mississauga, ON to Chicago bus

How much does a Mississauga, ON Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $58 and takes 16h 35m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Mississauga, ON to Chicago?

This route is offered by 1 companies with a range of ticket prices between $58 and $145. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Mississauga, ON to Chicago each day?

Every day, the Mississauga, ON to Chicago bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mississauga, ON to Chicago take?

The fastest bus from Mississauga, ON to Chicago is offered by FlixBus and takes 11h 20m. Bus tickets for this connection cost $103. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mississauga, ON to Chicago?

The earliest bus arriving in Chicago from Mississauga, ON starts at 5:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mississauga, ON to Chicago?

The latest bus trip departing from Mississauga, ON for Chicago starts at 11:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mississauga, ON Chicago route?

When traveling by bus from Mississauga, ON to Chicago, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mississauga, ON and Chicago?

You can check all the direct connections between Mississauga, ON and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Mississauga, ON to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mississauga, ON Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mississauga, ON Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mississauga, ON to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Mississauga, ON to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between Mississauga, ON and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mississauga, ON to Chicago?

Prices and availability for 8 trips between Mississauga, ON and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mississauga, ON to Chicago

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mississauga, ON and to Chicago

Here’s an overview of the most popular bus routes to Mississauga, ON and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Dallas to Mississauga, ON Bus Dallas to Mississauga, ON
Bus Whitby, ON - Mississauga, ON Bus Whitby, ON - Mississauga, ON
Buses from Rochester, NY to Mississauga, ON Buses from Rochester, NY to Mississauga, ON
Buses to Mississauga, ON from Cincinnati Buses to Mississauga, ON from Cincinnati
Bus from Matamoros to Chicago Bus from Matamoros to Chicago
From Mesa, AZ to Chicago bus From Mesa, AZ to Chicago bus
Bus Guadalupe, NL - Chicago Bus Guadalupe, NL - Chicago
Bus to Chicago from Louisville, KY Bus to Chicago from Louisville, KY
Popular Airport Shuttles to Mississauga, ON and to Chicago
CheckMyBus › Buses in Canada › Bus to Mississauga, ON › Bus to Chicago

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.