What is the best way to travel from Prague to Karlsruhe?
Looking for a trip? Compare all the available Trains and Buses for the journey to Karlsruhe from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Karlsruhe from Prague?
You can get to Karlsruhe with just $28 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/13/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 11:50:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/13/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 11:50:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 9h 20m
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/13/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 6:35:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/13/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 3:15:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 8h 35m
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FlixBus11h 10m04:15 PMPragueWilsonova Bus Station3:25 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/13/2026 4:15:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 3:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 11h 10m
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České dráhy11h 16m06:31 PMPragueTrain station Wilsonova5:47 AMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 3/13/2026 6:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 5:47:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 11h 16m
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České dráhy11h 6m06:31 PMPragueTrain station Wilsonova5:37 AMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 3/13/2026 6:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 5:37:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 11h 6m
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České dráhy8h 18m02:41 PMPragueHolesovice10:59 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Holesovice, Prague (Czech Republic) at 3/13/2026 2:41:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 10:59:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 8h 18m
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České dráhy9h 28m012:31 PMPragueTrain station Wilsonova9:59 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 3/13/2026 12:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 9:59:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 9h 28m
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České dráhy8h 28m012:31 PMPragueTrain station Wilsonova8:59 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 3/13/2026 12:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 8:59:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 8h 28m
Cheapest Buses Friday
Cheapest Trains Friday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/14/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 7h 50m
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FlixBus11h 25m02:30 AMPragueWilsonova Bus Station1:55 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/14/2026 2:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 1:55:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 25m
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FlixBus11h 25m03:50 AMPragueWilsonova Bus Station3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/14/2026 3:50:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 3:15:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 25m
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FlixBus10h 15m08:20 PMPragueWilsonova Bus Station6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/14/2026 8:20:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 6:35:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 15m
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FlixBus11h 0m011:50 PMPragueWilsonova Bus Station10:50 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/14/2026 11:50:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 10:50:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 0m
Cheapest Buses Saturday
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/15/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 3:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/15/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 6:35:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 35m
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FlixBus8h 10m010:25 PMPragueHradčanská6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 3/15/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 6:35:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 10m
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FlixBus8h 45m09:50 PMPragueNa Knížecí Station6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/15/2026 9:50:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 6:35:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 8h 45m
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FlixBus11h 25m03:50 AMPragueWilsonova Bus Station3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/15/2026 3:50:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 3:15:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 11h 25m
Cheapest Buses Sunday
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/16/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 3:15:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
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FlixBus12h 0m012:50 PMPragueHradčanská12:50 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 3/16/2026 12:50:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/17/2026 12:50:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 12h 0m
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FlixBus11h 25m02:30 AMPragueWilsonova Bus Station1:55 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/16/2026 2:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 1:55:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 25m
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FlixBus11h 25m03:50 AMPragueWilsonova Bus Station3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/16/2026 3:50:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 3:15:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 25m
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FlixBus11h 15m09:00 AMPragueWilsonova Bus Station8:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/16/2026 9:00:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 8:15:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 15m
Cheapest Buses Monday
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/18/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/18/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/18/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/18/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 9h 20m
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FlixBus10h 35m09:00 AMPragueWilsonova Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/18/2026 9:00:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/18/2026 7:35:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 35m
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FlixBus10h 15m08:20 PMPragueWilsonova Bus Station6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/18/2026 8:20:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/19/2026 6:35:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 15m
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FlixBus10h 25m010:55 AMPragueNa Knížecí Station9:20 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/18/2026 10:55:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/18/2026 9:20:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 25m
Cheapest Buses Wednesday
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/19/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/19/2026 11:50:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/19/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/19/2026 11:50:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 9h 20m
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/19/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/20/2026 6:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/19/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/19/2026 3:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/19/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/20/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
Cheapest Buses Thursday
What are the fastest trips from Prague to Karlsruhe?
You can get to Karlsruhe from Prague in just 7h 50m with a Bus from FlixBus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/13/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 6:35:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/13/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 3:15:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 8h 35m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/13/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 11:50:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/13/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 11:50:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 9h 20m
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FlixBus11h 10m04:15 PMPragueWilsonova Bus Station3:25 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/13/2026 4:15:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 3:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 11h 10m
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České dráhy8h 18m02:41 PMPragueHolesovice10:59 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Holesovice, Prague (Czech Republic) at 3/13/2026 2:41:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 10:59:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 8h 18m
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České dráhy8h 28m012:31 PMPragueTrain station Wilsonova8:59 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 3/13/2026 12:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 8:59:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 8h 28m
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České dráhy9h 28m012:31 PMPragueTrain station Wilsonova9:59 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 3/13/2026 12:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/13/2026 9:59:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 9h 28m
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České dráhy11h 6m06:31 PMPragueTrain station Wilsonova5:37 AMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 3/13/2026 6:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 5:37:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 11h 6m
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České dráhy11h 16m06:31 PMPragueTrain station Wilsonova5:47 AMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 3/13/2026 6:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 5:47:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 11h 16m
Fastest Buses Friday
Fastest Trains Friday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/14/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 7h 50m
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FlixBus10h 15m08:20 PMPragueWilsonova Bus Station6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/14/2026 8:20:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 6:35:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 15m
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FlixBus11h 0m011:50 PMPragueWilsonova Bus Station10:50 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/14/2026 11:50:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 10:50:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 0m
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FlixBus11h 25m02:30 AMPragueWilsonova Bus Station1:55 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/14/2026 2:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 1:55:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 25m
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FlixBus11h 25m03:50 AMPragueWilsonova Bus Station3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/14/2026 3:50:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/14/2026 3:15:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 25m
Fastest Buses Saturday
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FlixBus8h 10m010:25 PMPragueHradčanská6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 3/15/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 6:35:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 10m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/15/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 3:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/15/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 6:35:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 35m
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FlixBus8h 45m09:50 PMPragueNa Knížecí Station6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/15/2026 9:50:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 6:35:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 8h 45m
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FlixBus11h 25m03:50 AMPragueWilsonova Bus Station3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/15/2026 3:50:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/15/2026 3:15:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 11h 25m
Fastest Buses Sunday
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/16/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 3:15:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
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FlixBus11h 15m09:00 AMPragueWilsonova Bus Station8:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/16/2026 9:00:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 8:15:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 15m
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FlixBus11h 25m02:30 AMPragueWilsonova Bus Station1:55 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/16/2026 2:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 1:55:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 25m
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FlixBus11h 25m03:50 AMPragueWilsonova Bus Station3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/16/2026 3:50:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/16/2026 3:15:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 25m
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FlixBus12h 0m012:50 PMPragueHradčanská12:50 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 3/16/2026 12:50:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/17/2026 12:50:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 12h 0m
Fastest Buses Monday
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/18/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/18/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/18/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/18/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 9h 20m
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FlixBus10h 15m08:20 PMPragueWilsonova Bus Station6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/18/2026 8:20:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/19/2026 6:35:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 15m
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FlixBus10h 25m010:55 AMPragueNa Knížecí Station9:20 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/18/2026 10:55:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/18/2026 9:20:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 25m
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FlixBus10h 35m09:00 AMPragueWilsonova Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/18/2026 9:00:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/18/2026 7:35:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 35m
Fastest Buses Wednesday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/19/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/20/2026 6:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/19/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 3/19/2026 3:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/19/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/20/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/19/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/19/2026 11:50:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/19/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 3/19/2026 11:50:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 9h 20m
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Here you will find all operators and timetables for a
Bus from Prague to Karlsruhe
What are the most popular stations in Prague and Karlsruhe?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Karlsruhe you will be arriving at Central Station, Tullastraße / Verkehrsbetriebe Train Station or Heidehof Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Karlsruhe from Prague? With 5 connections between 2 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Karlsruhe, you can pay as low as $28 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Karlsruhe in just 7h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Karlsruhe are FlixBus and České dráhy, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Karlsruhe is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Ettlingen, and look at flights from Prague Airport, and landing at Karlsruhe/Baden-Baden Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Karlsruhe?
The most popular companies between Prague and Karlsruhe, are FlixBus and České dráhy. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Train companies: České dráhy
All you need to know when you travel from Prague to Karlsruhe
Check all information on comfort and services on all modes of transports from Prague to Karlsruhe. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Karlsruhe
How can I reach Karlsruhe from Prague?
Every day, there are on average 5 connections between Train and Bus, with which you can get to Karlsruhe from Prague.
How far is Karlsruhe from Prague?
The distance between Prague and Karlsruhe is 280.4 miles.
What is the most ecofriendly mode of transport between Prague and Karlsruhe?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 16 kgs, a car 77 kgs, and a flight 111 kgs.
What is the cheapest mode of transport from Prague to Karlsruhe?
You can get to Karlsruhe with just $28 by taking a Bus from FlixBus.
What is the fastest way to get from Prague to Karlsruhe?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Karlsruhe in just 7h 50m with a Bus from FlixBus.
More routes to Prague and to Karlsruhe
Looking for more options? Here you can see the most popular routes to Prague and to Karlsruhe. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin Brandenburg Airport to Prague
- Berlin to Prague
- Bremen to Prague
- Brno to Prague
- Budapest to Prague
- Dresden to Prague
- Florence to Prague
- Frankfurt am Main to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Leipzig to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Ostrava to Prague
- Regensburg to Prague
- Třebíč to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Karlsruhe
- Amsterdam to Karlsruhe
- Berlin to Karlsruhe
- Brussels to Karlsruhe
- Frankfurt am Main Airport to Karlsruhe
- Frankfurt am Main to Karlsruhe
- Freiburg to Karlsruhe
- Hamburg to Karlsruhe
- Linz to Karlsruhe
- Ludwigshafen to Karlsruhe
- Lyon to Karlsruhe
- Mannheim to Karlsruhe
- Memmingen Airport to Karlsruhe
- Milan to Karlsruhe
- Montpellier to Karlsruhe
- Munich to Karlsruhe
- Nuremberg to Karlsruhe
- Paris to Karlsruhe
- Stuttgart Airport to Karlsruhe
- Stuttgart to Karlsruhe
- Vienna to Karlsruhe
- Zurich to Karlsruhe
