What is the best way to travel from Prague to Karlsruhe?
Looking for a trip? Compare all the available Flights, Buses and Trains for the journey to Karlsruhe from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Karlsruhe from Prague?
You can get to Karlsruhe with just $27 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 6:35:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 50m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/16/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 11:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 6/16/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 11:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 9h 20m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/16/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 6:35:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 35m
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Wizz Air28h 10m011:30 AMPrague AirportPrague Airport - T1/23:40 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 11:30:00 AM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/17/2026 3:40:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 28h 10m
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Air Bagan27h 55m05:35 PMPrague AirportPrague Airport - T1/29:30 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 5:35:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/17/2026 9:30:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 27h 55m
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Buzz14h 40m07:10 AMPrague AirportPrague Airport - T1/29:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 7:10:00 AM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/16/2026 9:50:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 14h 40m
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Smartwings16h 35m06:00 PMPrague AirportPrague Airport - T1/210:35 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 6:00:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/17/2026 10:35:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 16h 35m
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České dráhy10h 50m012:33 AMPragueTrain station Wilsonova11:23 AMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 6/16/2026 12:33:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 11:23:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 10h 50m
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České dráhy9h 28m012:31 PMPragueTrain station Wilsonova9:59 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 6/16/2026 12:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 9:59:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 9h 28m
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České dráhy8h 50m01:35 PMPragueTrain station Wilsonova10:25 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 6/16/2026 1:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 10:25:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 8h 50m
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České dráhy8h 36m03:35 PMPragueTrain station Wilsonova12:11 AMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 6/16/2026 3:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 12:11:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 8h 36m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
Cheapest Trains Tuesday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/17/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/18/2026 6:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 7h 50m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/17/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 6/17/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 9h 20m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/17/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 3:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
Cheapest Buses Wednesday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/19/2026 6:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 50m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/18/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/18/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 6/18/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/18/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 9h 20m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/18/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/18/2026 3:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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R Airlines5h 45m03:30 PMPrague AirportPrague Airport - T1/29:15 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from R Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 3:30:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/18/2026 9:15:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 5h 45m
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Air Bagan22h 30m05:20 PMPrague AirportPrague Airport - T1/23:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 5:20:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/19/2026 3:50:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 22h 30m
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Ryanair10h 40m010:35 AMPrague AirportPrague Airport - T1/29:15 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 10:35:00 AM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/18/2026 9:15:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 10h 40m
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Buzz20h 10m07:40 PMPrague AirportPrague Airport - T1/23:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 7:40:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/19/2026 3:50:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 20h 10m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/19/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/20/2026 6:35:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 7h 50m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/19/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/19/2026 11:50:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 40m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 6/19/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/19/2026 11:50:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 9h 20m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/19/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/19/2026 3:15:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
Cheapest Buses Friday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/20/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/21/2026 6:35:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/20/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/20/2026 3:15:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/20/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/21/2026 6:35:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
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FlixBus8h 10m010:25 PMPragueHradčanská6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 6/20/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/21/2026 6:35:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 10m
Cheapest Buses Saturday
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/21/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/21/2026 3:15:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 8h 35m
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/21/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 6:35:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/21/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 6:35:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 35m
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FlixBus8h 10m010:25 PMPragueHradčanská6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 6/21/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 6:35:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 10m
Cheapest Buses Sunday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/22/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/23/2026 6:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 50m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/22/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 11:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 40m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/22/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/23/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus9h 20m02:30 PMPragueČerný Most11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 6/22/2026 2:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 11:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 20m
Cheapest Buses Monday
What are the fastest trips from Prague to Karlsruhe?
You can get to Karlsruhe from Prague in just 5h 45m with a Flight from R Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 6:35:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 50m
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FlixBus8h 10m010:25 PMPragueHradčanská6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 6/16/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 6:35:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 10m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/16/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 6:35:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 35m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/16/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 11:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 40m
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České dráhy8h 36m03:35 PMPragueTrain station Wilsonova12:11 AMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 6/16/2026 3:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 12:11:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 8h 36m
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České dráhy8h 50m01:35 PMPragueTrain station Wilsonova10:25 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 6/16/2026 1:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 10:25:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 8h 50m
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České dráhy8h 50m05:35 AMPragueTrain station Wilsonova2:25 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 6/16/2026 5:35:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 2:25:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 8h 50m
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České dráhy9h 28m012:31 PMPragueTrain station Wilsonova9:59 PMKarlsruheCentral Station0EconomyA Train from České dráhy goes from Train station Wilsonova, Prague (Czech Republic) at 6/16/2026 12:31:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/16/2026 9:59:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 9h 28m
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EasyJet Airline9h 40m012:10 PMPrague AirportPrague Airport - T1/29:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 12:10:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/16/2026 9:50:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 9h 40m
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Buzz14h 40m07:10 AMPrague AirportPrague Airport - T1/29:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 7:10:00 AM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/16/2026 9:50:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 14h 40m
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Smartwings16h 35m06:00 PMPrague AirportPrague Airport - T1/210:35 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 6:00:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/17/2026 10:35:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 16h 35m
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Air Bagan27h 55m05:35 PMPrague AirportPrague Airport - T1/29:30 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/16/2026 5:35:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/17/2026 9:30:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 27h 55m
Fastest Buses Tuesday
Fastest Trains Tuesday
Fastest Flights Tuesday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/17/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/18/2026 6:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/17/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 3:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/17/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/18/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/17/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/17/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 8h 40m
Fastest Buses Wednesday
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R Airlines5h 45m03:30 PMPrague AirportPrague Airport - T1/29:15 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from R Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 3:30:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/18/2026 9:15:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 5h 45m
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Ryanair10h 40m010:35 AMPrague AirportPrague Airport - T1/29:15 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 10:35:00 AM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/18/2026 9:15:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 10h 40m
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EasyJet Airline18h 5m09:45 PMPrague AirportPrague Airport - T1/23:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 9:45:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/19/2026 3:50:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 18h 5m
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Buzz20h 10m07:40 PMPrague AirportPrague Airport - T1/23:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 7:40:00 PM to Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) arriving at 6/19/2026 3:50:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 20h 10m
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/18/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/19/2026 6:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/18/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/18/2026 3:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/18/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/19/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/18/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/18/2026 11:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 8h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/19/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/20/2026 6:35:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 7h 50m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/19/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/19/2026 3:15:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/19/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/20/2026 6:35:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/19/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/19/2026 11:50:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 40m
Fastest Buses Friday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/20/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/21/2026 6:35:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 7h 50m
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FlixBus8h 10m010:25 PMPragueHradčanská6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 6/20/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/21/2026 6:35:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 10m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/20/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/20/2026 3:15:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/20/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/21/2026 6:35:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 35m
Fastest Buses Saturday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/21/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 6:35:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 50m
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FlixBus8h 10m010:25 PMPragueHradčanská6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 6/21/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 6:35:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 10m
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FlixBus8h 35m06:40 AMPragueÚAN Florenc3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/21/2026 6:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 6/21/2026 3:15:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 8h 35m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/21/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 6:35:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 35m
Fastest Buses Sunday
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FlixBus7h 50m010:45 PMPrague AirportPrague Airport - T1/26:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 6/22/2026 10:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/23/2026 6:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 50m
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FlixBus8h 10m010:25 PMPragueHradčanská6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 6/22/2026 10:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/23/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 10m
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FlixBus8h 35m010:00 PMPragueÚAN Florenc6:35 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/22/2026 10:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/23/2026 6:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 35m
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FlixBus8h 40m03:10 PMPragueÚAN Florenc11:50 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/22/2026 3:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 6/22/2026 11:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 8h 40m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Prague to Karlsruhe
What are the most popular stations in Prague and Karlsruhe?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Karlsruhe you will be arriving at Central Station, Tullastraße / Verkehrsbetriebe Train Station or Heidehof Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Karlsruhe from Prague? With 7 connections between 4 Flight, Bus and Train operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Karlsruhe, you can pay as low as $27 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from R Airlines: you will get to Karlsruhe in just 5h 45m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Karlsruhe are FlixBus, České dráhy and Air Bagan, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Karlsruhe is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Ettlingen, and look at flights from Prague Airport, and landing at Karlsruhe/Baden-Baden Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Karlsruhe?
The most popular companies between Prague and Karlsruhe, are FlixBus, České dráhy and Air Bagan. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Train companies: České dráhy
Airlines: Air Bagan, Buzz, EasyJet Airline and 4 more.
All you need to know when you travel from Prague to Karlsruhe
Check all information on comfort and services on all modes of transports from Prague to Karlsruhe. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Karlsruhe
How can I reach Karlsruhe from Prague?
Every day, there are on average 7 connections between Flight, Bus and Train, with which you can get to Karlsruhe from Prague.
How far is Karlsruhe from Prague?
The distance between Prague and Karlsruhe is 280.4 miles.
What is the most ecofriendly mode of transport between Prague and Karlsruhe?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 16 kgs, a car 77 kgs, and a flight 111 kgs.
What is the cheapest mode of transport from Prague to Karlsruhe?
You can get to Karlsruhe with just $27 by taking a Bus from FlixBus.
What is the fastest way to get from Prague to Karlsruhe?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Karlsruhe in just 5h 45m with a Flight from R Airlines.
More routes to Prague and to Karlsruhe
Looking for more options? Here you can see the most popular routes to Prague and to Karlsruhe. Simply click on a connection, and you’ll find all the details about the route!
