Bus from Prague to Karlsruhe from $33

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Prague to Karlsruhe

Here is a selection of the cheapest bus trips from the schedule from Prague to Karlsruhe from various bus operators like FlixBus for the next days.

today
$43
tomorrow
$41
Friday
$52
Saturday
$48
Sunday
$47
Monday
$46
Tuesday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 9h 55m 5:30 PM Prague Wilsonova Bus Station 3:25 AM Karlsruhe Central Station  Economy $43
FlixBus 10h 15m 8:20 PM Prague Wilsonova Bus Station 6:35 AM Karlsruhe Central Station  Economy $43
FlixBus 11h 0m 11:50 PM Prague Wilsonova Bus Station 10:50 AM Karlsruhe Central Station  Economy $43
FlixBus 8h 45m 9:50 PM Prague Na Knížecí Station 6:35 AM Karlsruhe Central Station  Economy $43
FlixBus 11h 25m 2:30 AM Prague Wilsonova Bus Station 1:55 PM Karlsruhe Central Station  Economy $44

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 11h 25m 2:30 AM Prague Wilsonova Bus Station 1:55 PM Karlsruhe Central Station  Economy $41
FlixBus 11h 50m 3:25 AM Prague Wilsonova Bus Station 3:15 PM Karlsruhe Central Station  Economy $41
FlixBus 9h 55m 5:30 PM Prague Wilsonova Bus Station 3:25 AM Karlsruhe Central Station  Economy $41
FlixBus 10h 15m 8:20 PM Prague Wilsonova Bus Station 6:35 AM Karlsruhe Central Station  Economy $41
FlixBus 11h 35m 3:40 AM Prague Na Knížecí Station 3:15 PM Karlsruhe Central Station  Economy $41

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 8h 40m 3:10 PM Prague ÚAN Florenc 11:50 PM Karlsruhe Central Station  Economy $52
FlixBus 8h 35m 10:00 PM Prague ÚAN Florenc 6:35 AM Karlsruhe Central Station  Economy $52
FlixBus 9h 20m 2:30 PM Prague Černý Most 11:50 PM Karlsruhe Central Station  Economy $52
FlixBus 8h 10m 10:25 PM Prague Hradčanská 6:35 AM Karlsruhe Central Station  Economy $52
FlixBus 11h 50m 3:25 AM Prague Wilsonova Bus Station 3:15 PM Karlsruhe Central Station  Economy $55
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $11? You can find the corresponding connections below.
    • FlixBus
      10h 5m
      0
      8:30 PM
      Prague
      Hradčanská
      8:45 PM
      Prague Airport
      Prague Airport - T1/2
      0
      FlixBus
      Economy
      $4
      • Waiting Time 2h 0m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $37
    Travel time is 1h 55m longer, but you will save $11

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 8h 40m 3:10 PM Prague ÚAN Florenc 11:50 PM Karlsruhe Central Station  Economy $48
FlixBus 9h 20m 2:30 PM Prague Černý Most 11:50 PM Karlsruhe Central Station  Economy $48
FlixBus 8h 45m 9:50 PM Prague Na Knížecí Station 6:35 AM Karlsruhe Central Station  Economy $50
FlixBus 8h 35m 6:40 AM Prague ÚAN Florenc 3:15 PM Karlsruhe Central Station  Economy $50
FlixBus 11h 25m 2:30 AM Prague Wilsonova Bus Station 1:55 PM Karlsruhe Central Station  Economy $51
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      10h 5m
      0
      8:30 PM
      Prague
      Hradčanská
      8:45 PM
      Prague Airport
      Prague Airport - T1/2
      0
      FlixBus
      Economy
      $4
      • Waiting Time 2h 0m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $37
    Travel time is 1h 30m longer, but you will save $7

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 8h 40m 3:10 PM Prague ÚAN Florenc 11:50 PM Karlsruhe Central Station  Economy $47
FlixBus 8h 35m 10:00 PM Prague ÚAN Florenc 6:35 AM Karlsruhe Central Station  Economy $47
FlixBus 8h 10m 10:25 PM Prague Hradčanská 6:35 AM Karlsruhe Central Station  Economy $47
FlixBus 9h 20m 2:30 PM Prague Černý Most 11:50 PM Karlsruhe Central Station  Economy $47
FlixBus 11h 50m 3:25 AM Prague Wilsonova Bus Station 3:15 PM Karlsruhe Central Station  Economy $55
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $6? You can find the corresponding connections below.
    • FlixBus
      10h 5m
      0
      8:30 PM
      Prague
      Hradčanská
      8:45 PM
      Prague Airport
      Prague Airport - T1/2
      0
      FlixBus
      Economy
      $4
      • Waiting Time 2h 0m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $37
    Travel time is 1h 55m longer, but you will save $6

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 11h 50m 3:25 AM Prague Wilsonova Bus Station 3:15 PM Karlsruhe Central Station  Economy $46
FlixBus 11h 35m 3:40 AM Prague Na Knížecí Station 3:15 PM Karlsruhe Central Station  Economy $46
FlixBus 8h 45m 9:50 PM Prague Na Knížecí Station 6:35 AM Karlsruhe Central Station  Economy $46
FlixBus 8h 45m 3:05 PM Prague Zličín 11:50 PM Karlsruhe Central Station  Economy $46
FlixBus 11h 10m 7:25 PM Prague Zličín 6:35 AM Karlsruhe Central Station  Economy $46
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $5? You can find the corresponding connections below.
    • FlixBus
      10h 5m
      0
      8:30 PM
      Prague
      Hradčanská
      8:45 PM
      Prague Airport
      Prague Airport - T1/2
      0
      FlixBus
      Economy
      $4
      • Waiting Time 2h 0m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $37
    Travel time is 1h 20m longer, but you will save $5

Best Price Offer: The price for the cheapest bus from Prague to Karlsruhe is $33 on 9/9/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Prague and Karlsruhe

See here how frequent the connections between Prague and Karlsruhe are, during different times and days of the week.
Sunday is the busiest day, with more than 20 daily buses from Prague to Karlsruhe. Monday has instead the fewest connections, with only 19 daily coaches between Prague and Karlsruhe.
The busiest time of the day is the Afternoon, with 36 buses from Prague to Karlsruhe, while Night sees the fewest connections between Prague and Karlsruhe, with 18 offers.

Facts about the bus from Prague to Karlsruhe

Compare all providers like FlixBus that travel 19 times every day by bus from Prague to Karlsruhe in one click! Book your bus ticket from Prague to Karlsruhe starting from $33!

Cheapest Bus $33
Fastest Bus 8h 10m
Earliest Bus 2:30 AM
Latest Bus 10:25 PM
Daily Bus Routes 19 Ø
Distance 280.4 miles
Bus Companies FlixBus

Cheapest bus connections from Prague to Karlsruhe

Every day, 19 buses from 1 bus companies leave Prague for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/19/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/16
Monday 08/17
Tuesday 08/18
Wednesday 08/19
$43
Thursday 08/20
$41
Friday 08/21
$52
Saturday 08/22
$48
Sunday 08/23
$47
Monday 08/24
$46
Tuesday 08/25
$43
Wednesday 08/26
$39
Thursday 08/27
$42
Friday 08/28
$46
Saturday 08/29
$47
Sunday 08/30
$45
Monday 08/31
$39
Tuesday 09/01
$37
Wednesday 09/02
$35
Thursday 09/03
$35
Friday 09/04
$39
Saturday 09/05
$38
Sunday 09/06
$45
Monday 09/07
$34
Tuesday 09/08
$36
Wednesday 09/09
$33
Thursday 09/10
$33
Friday 09/11
$42
Saturday 09/12

The cheapest time to travel from Prague to Karlsruhe

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Karlsruhe, for the next 30 days.
With a price starting from $33, Wednesday is the cheapest day for a bus from Prague to Karlsruhe. Friday instead is the most expensive day with prices starting from $39.
Night is the cheapest day time for bus tickets from Prague to Karlsruhe, with $33. Morning is the most expensive time of the day with prices starting from $41.

How to save money travelling from Prague to Karlsruhe

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Karlsruhe are also emptier.

All bus stations and stops in Prague and Karlsruhe

In the map below, you can see where to find all bus stations in Prague and Karlsruhe.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Karlsruhe? Compare all modes of transports from Prague to Karlsruhe.

Service and Comfort on the bus from Prague to Karlsruhe

Want to know which seat classes are available on the buses from Prague to Karlsruhe? Or which bus companies serve the route Prague to Karlsruhe? Below you will find answers to your questions.

FAQs about the Prague to Karlsruhe bus

How much does a Prague Karlsruhe bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $33 and takes 8h 35m to reach Karlsruhe. Compare offers to save money!

How much could I save by comparing buses from Prague to Karlsruhe?

This route is offered by 1 companies with a range of ticket prices between $33 and $89. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Karlsruhe.

On average, how many connections are available from Prague to Karlsruhe each day?

Every day, the Prague to Karlsruhe bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Karlsruhe take?

The fastest bus from Prague to Karlsruhe is offered by FlixBus and takes 8h 10m. Bus tickets for this connection cost $50. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Karlsruhe?

The earliest bus arriving in Karlsruhe from Prague starts at 2:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Karlsruhe?

The latest bus trip departing from Prague for Karlsruhe starts at 10:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Karlsruhe route?

When traveling by bus from Prague to Karlsruhe, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Karlsruhe?

You can check all the direct connections between Prague and Karlsruhe by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Prague to Karlsruhe bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Karlsruhe bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Karlsruhe bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Karlsruhe on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Karlsruhe?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 19 daily trips between Prague and Karlsruhe. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Karlsruhe?

Prices and availability for 19 trips between Prague and Karlsruhe change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Karlsruhe

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Karlsruhe

Here’s an overview of the most popular bus routes to Prague and to Karlsruhe. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Kornwestheim to Prague Buses from Kornwestheim to Prague
Buses Chomutov - Prague Buses Chomutov - Prague
Bus to Prague from Pula Bus to Prague from Pula
From Stockholm to Prague bus From Stockholm to Prague bus
Heidelberg to Karlsruhe bus Heidelberg to Karlsruhe bus
Bus Bielefeld to Karlsruhe Bus Bielefeld to Karlsruhe
Buses Szczecin - Karlsruhe Buses Szczecin - Karlsruhe
Buses Przemyśl - Karlsruhe Buses Przemyśl - Karlsruhe
Popular Airport Shuttles to Prague and to Karlsruhe
CheckMyBus › Buses in Czech Republic › Bus to Prague › Bus to Karlsruhe

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.