Bus from Prague to Karlsruhe from $32

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Prague to Karlsruhe

Here is a selection of the cheapest bus trips from the schedule from Prague to Karlsruhe from various bus operators like FlixBus for the next days.

today
from $38
tomorrow
from $36
Thursday
from $36
Friday
from $37
Saturday
from $44
Sunday
from $42
Monday
from $32

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    8h 20m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    8h 40m
    0
    9:55 PM
    Prague
    ÚAN Florenc
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    8h 35m
    0
    6:40 AM
    Prague
    ÚAN Florenc
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $40
  • FlixBus
    8h 40m
    0
    3:10 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $40
  • FlixBus
    9h 20m
    0
    2:30 PM
    Prague
    Černý Most
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $40
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $4? You can find the corresponding connections below.
    • Terravision
      9h 50m
      0
      8:45 PM
      Prague
      Hradčanská
      9:15 PM
      Prague Airport
      Prague Airport
      0
      Terravision
      Economy
      $5
      • Waiting Time 1h 30m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $29
    Travel time is 1h 30m longer, but you will save $4

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    10h 20m
    0
    8:15 PM
    Prague
    Wilsonova Bus Station
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    11h 25m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    10h 35m
    0
    9:00 AM
    Prague
    Wilsonova Bus Station
    7:35 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    10h 25m
    0
    5:15 PM
    Prague
    Wilsonova Bus Station
    3:40 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    11h 5m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $5? You can find the corresponding connections below.
    • RegioJet
      10h 5m
      0
      8:30 PM
      Prague
      ÚAN Florenc
      9:00 PM
      Prague Airport
      Prague Airport - T1/2
      0
      RegioJet
      Economy
      $5
      • Waiting Time 1h 45m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $27
    Travel Time is 0h 15m shorter, and you will save $5

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    8h 20m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    8h 40m
    0
    9:55 PM
    Prague
    ÚAN Florenc
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    8h 35m
    0
    6:40 AM
    Prague
    ÚAN Florenc
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    8h 40m
    0
    3:10 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    9h 20m
    0
    2:30 PM
    Prague
    Černý Most
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $5? You can find the corresponding connections below.
    • RegioJet
      10h 5m
      0
      8:30 PM
      Prague
      ÚAN Florenc
      9:00 PM
      Prague Airport
      Prague Airport - T1/2
      0
      RegioJet
      Economy
      $5
      • Waiting Time 1h 45m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $27
    Travel time is 1h 45m longer, but you will save $5

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    8h 20m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    8h 40m
    0
    9:55 PM
    Prague
    ÚAN Florenc
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    8h 35m
    0
    6:40 AM
    Prague
    ÚAN Florenc
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    8h 40m
    0
    3:10 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    9h 20m
    0
    2:30 PM
    Prague
    Černý Most
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $38
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $6? You can find the corresponding connections below.
    • RegioJet
      10h 5m
      0
      8:30 PM
      Prague
      ÚAN Florenc
      9:00 PM
      Prague Airport
      Prague Airport - T1/2
      0
      RegioJet
      Economy
      $5
      • Waiting Time 1h 45m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $27
    Travel time is 1h 45m longer, but you will save $6

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    8h 20m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    8h 40m
    0
    9:55 PM
    Prague
    ÚAN Florenc
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    8h 40m
    0
    3:10 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $45
  • FlixBus
    9h 20m
    0
    2:30 PM
    Prague
    Černý Most
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $45
  • FlixBus
    8h 35m
    0
    6:40 AM
    Prague
    ÚAN Florenc
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $46
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $13? You can find the corresponding connections below.
    • RegioJet
      10h 5m
      0
      8:30 PM
      Prague
      ÚAN Florenc
      9:00 PM
      Prague Airport
      Prague Airport - T1/2
      0
      RegioJet
      Economy
      $5
      • Waiting Time 1h 45m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $27
    Travel time is 1h 45m longer, but you will save $13

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    8h 20m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $42
  • FlixBus
    8h 40m
    0
    9:55 PM
    Prague
    ÚAN Florenc
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $42
  • FlixBus
    8h 35m
    0
    6:40 AM
    Prague
    ÚAN Florenc
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    10h 25m
    0
    5:15 PM
    Prague
    Wilsonova Bus Station
    3:40 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $52
  • FlixBus
    10h 20m
    0
    8:15 PM
    Prague
    Wilsonova Bus Station
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $52
  • Did you know that if you travel from Prague to Karlsruhe via Prague Airport, you can save more than $12? You can find the corresponding connections below.
    • RegioJet
      10h 5m
      0
      8:30 PM
      Prague
      ÚAN Florenc
      9:00 PM
      Prague Airport
      Prague Airport - T1/2
      0
      RegioJet
      Economy
      $5
      • Waiting Time 1h 45m
    • FlixBus
      7h 50m
      0
      10:45 PM
      Prague Airport
      Prague Airport - T1/2
      6:35 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $25
    Travel time is 1h 45m longer, but you will save $12

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    8h 20m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $32
  • FlixBus
    8h 40m
    0
    9:55 PM
    Prague
    ÚAN Florenc
    6:35 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $32
  • FlixBus
    8h 35m
    0
    6:40 AM
    Prague
    ÚAN Florenc
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $33
  • FlixBus
    8h 40m
    0
    3:10 PM
    Prague
    ÚAN Florenc
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $33
  • FlixBus
    9h 20m
    0
    2:30 PM
    Prague
    Černý Most
    11:50 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $33

Frequency of bus connections between Prague and Karlsruhe

See here how frequent the connections between Prague and Karlsruhe are, during different times and days of the week.
Monday is the busiest day, with more than 18 daily buses from Prague to Karlsruhe. Sunday has instead the fewest connections, with only 17 daily coaches between Prague and Karlsruhe.
The busiest time of the day is the Afternoon, with 48 buses from Prague to Karlsruhe, while Night sees the fewest connections between Prague and Karlsruhe, with 14 offers.

Facts about the bus from Prague to Karlsruhe

Compare all providers like FlixBus that travel 17 times every day by bus from Prague to Karlsruhe in one click! Book your bus ticket from Prague to Karlsruhe starting from $32!

Cheapest Bus $32
Fastest Bus 8h 10m
Earliest Bus 3:50 AM
Latest Bus 10:15 PM
Daily Bus Routes 17 Ø
Distance 280.4 miles
Bus Companies FlixBus

Cheapest bus connections from Prague to Karlsruhe

Every day, 17 buses from 1 bus companies leave Prague for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/08/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/06
Monday 07/07
Tuesday 07/08
$38
Wednesday 07/09
$36
Thursday 07/10
$36
Friday 07/11
$37
Saturday 07/12
$44
Sunday 07/13
$42
Monday 07/14
$32
Tuesday 07/15
$32
Wednesday 07/16
$32
Thursday 07/17
$32
Friday 07/18
$39
Saturday 07/19
$36
Sunday 07/20
$33
Monday 07/21
$35
Tuesday 07/22
$32
Wednesday 07/23
$34
Thursday 07/24
$34
Friday 07/25
$38
Saturday 07/26
$38
Sunday 07/27
$42
Monday 07/28
Tuesday 07/29
Wednesday 07/30
$36
Thursday 07/31
Friday 08/01
Saturday 08/02

The cheapest time to travel from Prague to Karlsruhe

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Karlsruhe, for the next 30 days.
With a price starting from $32, Monday is the cheapest day for a bus from Prague to Karlsruhe. Saturday instead is the most expensive day with prices starting from $44.
Evening is the cheapest day time for bus tickets from Prague to Karlsruhe, with $32. Night is the most expensive time of the day with prices starting from $37.

How to save money travelling from Prague to Karlsruhe

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Karlsruhe are also emptier.

Beloved bus companies from Prague to Karlsruhe

These are the most booked bus companies between Prague to Karlsruhe from our users.

FlixBus from Prague to Karlsruhe

FlixBus

Here you will find the key facts about the FlixBus bus route Prague to Karlsruhe:

Cheapest Price $32
Fastest Bus 8h 10m
Earliest Bus 3:50 AM
Last Bus 10:15 PM
Daily Connections 17 Ø
Found on 7/4/2025

All bus stations and stops in Prague and Karlsruhe

In the map below, you can see where to find all bus stations in Prague and Karlsruhe.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Karlsruhe? Compare all modes of transports from Prague to Karlsruhe.

Service and Comfort on the bus from Prague to Karlsruhe

Want to know which seat classes are available on the buses from Prague to Karlsruhe? Or which bus companies serve the route Prague to Karlsruhe? Below you will find answers to your questions.

FAQs about the Prague to Karlsruhe bus

How much does a Prague Karlsruhe bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $32 and takes 8h 20m to reach Karlsruhe. Compare offers to save money!

How much could I save by comparing buses from Prague to Karlsruhe?

This route is offered by 1 companies with a range of ticket prices between $32 and $73. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Karlsruhe.

On average, how many connections are available from Prague to Karlsruhe each day?

Every day, the Prague to Karlsruhe bus route is served by approximately 17 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Karlsruhe take?

The fastest bus from Prague to Karlsruhe is offered by FlixBus and takes 8h 10m. Bus tickets for this connection cost $53. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Karlsruhe?

The earliest bus arriving in Karlsruhe from Prague starts at 3:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Karlsruhe?

The latest bus trip departing from Prague for Karlsruhe starts at 10:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Karlsruhe route?

When traveling by bus from Prague to Karlsruhe, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Karlsruhe?

You can check all the direct connections between Prague and Karlsruhe by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Prague to Karlsruhe bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Karlsruhe bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Karlsruhe bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Karlsruhe on your planned travel date.

Available seat classes which are offered on the bus route Prague to Karlsruhe

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Karlsruhe

Here’s an overview of the most popular bus routes to Prague and to Karlsruhe. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Brno to Prague bus From Brno to Prague bus
Krakow to Prague bus Krakow to Prague bus
Buses from Paris to Prague Buses from Paris to Prague
Warsaw to Prague bus Warsaw to Prague bus
Buses to Karlsruhe from Novi Sad Buses to Karlsruhe from Novi Sad
Buses from Pforzheim to Karlsruhe Buses from Pforzheim to Karlsruhe
Bus Zagreb to Karlsruhe Bus Zagreb to Karlsruhe
Buses from Strasbourg to Karlsruhe Buses from Strasbourg to Karlsruhe
Popular Airport Shuttles to Prague and to Karlsruhe
CheckMyBus › Buses in Czech Republic › Bus to Prague › Bus to Karlsruhe

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.