What is the best way to travel from Prague to Pisa?
Looking for a trip? Compare all the available Buses for the journey to Pisa from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Pisa from Prague?
You can get to Pisa with just $80 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus23h 25m02:30 PMPragueČerný Most1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 12/16/2025 2:30:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/17/2025 1:55:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 23h 25m
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/16/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/17/2025 1:55:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 30m
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FlixBus20h 10m05:45 PMPragueNa Knížecí Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/16/2025 5:45:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/17/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 20h 10m
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FlixBus20h 20m05:35 PMPragueWilsonova Bus Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/16/2025 5:35:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/17/2025 1:55:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 20h 20m
Cheapest Buses Tuesday
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FlixBus21h 55m07:25 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/17/2025 7:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/18/2025 5:20:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 21h 55m
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FlixBus24h 20m08:20 PMPragueWilsonova Bus Station8:40 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/17/2025 8:20:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/18/2025 8:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 24h 20m
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FlixBus26h 30m010:15 PMPragueNa Knížecí Station12:45 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/17/2025 10:15:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 12:45:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 26h 30m
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FlixBus28h 40m06:45 PMPragueRoztyly11:25 PMPisaParking Aurelia0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/17/2025 6:45:00 PM to Parking Aurelia, Pisa (Italy) arriving at 12/18/2025 11:25:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 28h 40m
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FlixBus23h 25m02:30 PMPragueČerný Most1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 12/17/2025 2:30:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/18/2025 1:55:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 23h 25m
Cheapest Buses Wednesday
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FlixBus22h 20m01:05 PMPragueWilsonova Bus Station11:25 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/18/2025 1:05:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 11:25:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 22h 20m
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FlixBus21h 55m07:25 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/18/2025 7:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 5:20:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 21h 55m
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FlixBus22h 15m02:30 AMPragueWilsonova Bus Station12:45 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/18/2025 2:30:00 AM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 12:45:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 22h 15m
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FlixBus24h 10m05:10 PMPragueRoztyly5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/18/2025 5:10:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 5:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 24h 10m
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FlixBus25h 5m012:50 PMPragueHradčanská1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 12/18/2025 12:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 1:55:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 25h 5m
Cheapest Buses Thursday
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/19/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 1:55:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 16h 30m
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FlixBus19h 5m06:50 PMPrague AirportPrague Airport - T1/21:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/19/2025 6:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 1:55:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 19h 5m
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FlixBus22h 20m01:05 PMPragueWilsonova Bus Station11:25 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/19/2025 1:05:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 11:25:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 22h 20m
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FlixBus22h 25m06:55 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/19/2025 6:55:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 5:20:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 22h 25m
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FlixBus22h 5m011:50 PMPragueWilsonova Bus Station9:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/19/2025 11:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 9:55:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 22h 5m
Cheapest Buses Friday
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/20/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 1:55:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 16h 30m
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FlixBus19h 5m06:50 PMPrague AirportPrague Airport - T1/21:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 6:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 1:55:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 19h 5m
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FlixBus22h 20m01:05 PMPragueWilsonova Bus Station11:25 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/20/2025 1:05:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 11:25:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 22h 20m
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FlixBus21h 55m07:25 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/20/2025 7:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 5:20:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 21h 55m
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FlixBus22h 5m011:50 PMPragueWilsonova Bus Station9:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/20/2025 11:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 9:55:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 22h 5m
Cheapest Buses Saturday
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/21/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 1:55:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 16h 30m
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FlixBus19h 5m06:50 PMPrague AirportPrague Airport - T1/21:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/21/2025 6:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 1:55:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 19h 5m
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FlixBus22h 20m01:05 PMPragueWilsonova Bus Station11:25 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/21/2025 1:05:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 11:25:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 22h 20m
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FlixBus20h 10m05:45 PMPragueNa Knížecí Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/21/2025 5:45:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 1:55:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 20h 10m
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FlixBus20h 55m08:25 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/21/2025 8:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 5:20:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 20h 55m
Cheapest Buses Sunday
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/22/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 1:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 16h 30m
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FlixBus19h 5m06:50 PMPrague AirportPrague Airport - T1/21:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 6:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 1:55:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 19h 5m
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FlixBus22h 20m010:20 PMPragueRoztyly8:40 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/22/2025 10:20:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 8:40:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 22h 20m
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FlixBus20h 20m05:35 PMPragueWilsonova Bus Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/22/2025 5:35:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 1:55:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 20h 20m
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FlixBus20h 10m05:45 PMPragueNa Knížecí Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/22/2025 5:45:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 1:55:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 20h 10m
Cheapest Buses Monday
What are the fastest trips from Prague to Pisa?
You can get to Pisa from Prague in just 16h 30m with a Bus from FlixBus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/16/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/17/2025 1:55:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 30m
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FlixBus20h 10m05:45 PMPragueNa Knížecí Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/16/2025 5:45:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/17/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 20h 10m
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FlixBus20h 20m05:35 PMPragueWilsonova Bus Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/16/2025 5:35:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/17/2025 1:55:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 20h 20m
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FlixBus23h 25m02:30 PMPragueČerný Most1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 12/16/2025 2:30:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/17/2025 1:55:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 23h 25m
Fastest Buses Tuesday
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FlixBus21h 55m07:25 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/17/2025 7:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/18/2025 5:20:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 21h 55m
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FlixBus23h 25m02:30 PMPragueČerný Most1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 12/17/2025 2:30:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/18/2025 1:55:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 23h 25m
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FlixBus24h 20m08:20 PMPragueWilsonova Bus Station8:40 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/17/2025 8:20:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/18/2025 8:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 24h 20m
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FlixBus26h 30m010:15 PMPragueNa Knížecí Station12:45 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/17/2025 10:15:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 12:45:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 26h 30m
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FlixBus28h 40m06:45 PMPragueRoztyly11:25 PMPisaParking Aurelia0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/17/2025 6:45:00 PM to Parking Aurelia, Pisa (Italy) arriving at 12/18/2025 11:25:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 28h 40m
Fastest Buses Wednesday
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FlixBus21h 55m07:25 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/18/2025 7:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 5:20:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 21h 55m
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FlixBus22h 15m02:30 AMPragueWilsonova Bus Station12:45 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/18/2025 2:30:00 AM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 12:45:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 22h 15m
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FlixBus22h 20m01:05 PMPragueWilsonova Bus Station11:25 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/18/2025 1:05:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 11:25:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 22h 20m
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FlixBus24h 10m05:10 PMPragueRoztyly5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/18/2025 5:10:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 5:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 24h 10m
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FlixBus25h 5m012:50 PMPragueHradčanská1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 12/18/2025 12:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/19/2025 1:55:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 25h 5m
Fastest Buses Thursday
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/19/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 1:55:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 16h 30m
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FlixBus19h 5m06:50 PMPrague AirportPrague Airport - T1/21:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/19/2025 6:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 1:55:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 19h 5m
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FlixBus22h 5m011:50 PMPragueWilsonova Bus Station9:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/19/2025 11:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 9:55:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 22h 5m
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FlixBus22h 20m01:05 PMPragueWilsonova Bus Station11:25 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/19/2025 1:05:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 11:25:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 22h 20m
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FlixBus22h 25m06:55 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/19/2025 6:55:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/20/2025 5:20:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 22h 25m
Fastest Buses Friday
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/20/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 1:55:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 16h 30m
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FlixBus19h 5m06:50 PMPrague AirportPrague Airport - T1/21:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 6:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 1:55:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 19h 5m
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FlixBus21h 55m07:25 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/20/2025 7:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 5:20:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 21h 55m
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FlixBus22h 5m011:50 PMPragueWilsonova Bus Station9:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/20/2025 11:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 9:55:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 22h 5m
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FlixBus22h 20m01:05 PMPragueWilsonova Bus Station11:25 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/20/2025 1:05:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/21/2025 11:25:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 22h 20m
Fastest Buses Saturday
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/21/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 1:55:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 16h 30m
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FlixBus19h 5m06:50 PMPrague AirportPrague Airport - T1/21:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/21/2025 6:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 1:55:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 19h 5m
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FlixBus20h 10m05:45 PMPragueNa Knížecí Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/21/2025 5:45:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 1:55:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 20h 10m
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FlixBus20h 55m08:25 PMPragueZličín5:20 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/21/2025 8:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 5:20:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 20h 55m
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FlixBus22h 20m01:05 PMPragueWilsonova Bus Station11:25 AMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/21/2025 1:05:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/22/2025 11:25:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 22h 20m
Fastest Buses Sunday
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FlixBus16h 30m09:25 PMPragueÚAN Florenc1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/22/2025 9:25:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 1:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 16h 30m
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FlixBus19h 5m06:50 PMPrague AirportPrague Airport - T1/21:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 6:50:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 1:55:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 19h 5m
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FlixBus20h 10m05:45 PMPragueNa Knížecí Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/22/2025 5:45:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 1:55:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 20h 10m
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FlixBus20h 20m05:35 PMPragueWilsonova Bus Station1:55 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/22/2025 5:35:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 1:55:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 20h 20m
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FlixBus22h 20m010:20 PMPragueRoztyly8:40 PMPisaPietrasantina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/22/2025 10:20:00 PM to Pietrasantina Bus Station, Pisa (Italy) arriving at 12/23/2025 8:40:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 22h 20m
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Here you will find all operators and timetables for a
Bus from Prague to Pisa
What are the most popular stations in Prague and Pisa?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Pisa you will be arriving at Central Bus Station, Pietrasantina Bus Station or Central Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Pisa from Prague? With 4 connections between 1 Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Pisa, you can pay as low as $80 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Pisa in just 16h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Pisa are FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Pisa is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Pisa Airport, and look at flights from Prague Airport, and landing at Pisa Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Pisa?
The most popular companies between Prague and Pisa, are FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
All you need to know when you travel from Prague to Pisa
Check all information on comfort and services on all modes of transports from Prague to Pisa. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Pisa
How can I reach Pisa from Prague?
Every day, there are on average 4 connections between Bus, with which you can get to Pisa from Prague.
How far is Pisa from Prague?
The distance between Prague and Pisa is 478.5 miles.
What is the most ecofriendly mode of transport between Prague and Pisa?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 21 kgs of CO2, a train 27 kgs, a car 131 kgs, and a flight 189 kgs.
What is the cheapest mode of transport from Prague to Pisa?
You can get to Pisa with just $80 by taking a Bus from FlixBus.
What is the fastest way to get from Prague to Pisa?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Pisa in just 16h 30m with a Bus from FlixBus.
More routes to Prague and to Pisa
Looking for more options? Here you can see the most popular routes to Prague and to Pisa. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bern to Prague
- Bratislava to Prague
- Brno to Prague
- Chemnitz to Prague
- Dresden to Prague
- Florence to Prague
- Istanbul to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- London to Prague
- Lyon to Prague
- Memmingen to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Teplice to Prague
- Třebíč to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Pisa
- Bari to Pisa
- Bologna to Pisa
- Catania to Pisa
- Cosenza to Pisa
- Empoli to Pisa
- Florence to Pisa
- Frosinone to Pisa
- Genoa to Pisa
- La Spezia to Pisa
- Marseille to Pisa
- Milan Malpensa Airport to Pisa
- Milan to Pisa
- Naples to Pisa
- Palermo to Pisa
- Parma to Pisa
- Pescara to Pisa
- Rome Fiumicino Airport to Pisa
- Rome to Pisa
- Sala Consilina to Pisa
- Siena to Pisa
- Turin to Pisa
- Venice to Pisa

