What is the best way to travel from Rome to Karlsruhe?
Looking for a trip? Compare all the available Buses and Carpool for the journey to Karlsruhe from Rome. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Karlsruhe from Rome?
You can get to Karlsruhe with just $79 by taking a Carpool from BlaBlaCar, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/27/2025 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 8:20:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 21h 35m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 11:10:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 18h 35m
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FlixBus20h 40m010:55 PMRomeTiburtina Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 10:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 7:35:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 20h 40m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/27/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 12:10:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 18h 45m
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FlixBus17h 5m010:40 AMRomeTiburtina Bus Station3:45 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 10:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 3:45:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 17h 5m
Cheapest Buses Saturday
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/28/2025 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 8:20:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 21h 35m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/28/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 11:10:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 18h 35m
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FlixBus19h 45m09:00 PMRomeTiburtina Bus Station4:45 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/28/2025 9:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 4:45:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 19h 45m
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FlixBus18h 10m09:30 AMRomeTiburtina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/28/2025 9:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 3:40:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 18h 10m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/28/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 12:10:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 18h 45m
Cheapest Buses Sunday
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FlixBus24h 10m03:30 PMRome Ciampino AirportRome Ciampino Airport3:40 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/29/2025 3:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 3:40:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 24h 10m
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FlixBus17h 35m010:10 AMRomeTiburtina Bus Station3:45 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/29/2025 10:10:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 3:45:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 17h 35m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/29/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 12:10:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 18h 45m
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FlixBus17h 45m09:25 AMRomeTiburtina Bus Station3:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/29/2025 9:25:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 3:10:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 17h 45m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/29/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 11:10:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 18h 35m
Cheapest Buses Monday
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FlixBus20h 35m09:00 PMRomeTiburtina Bus Station5:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/30/2025 9:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/31/2025 5:35:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 20h 35m
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/30/2025 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/31/2025 8:20:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 21h 35m
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FlixBus28h 30m010:40 PMRome Ciampino AirportRome Ciampino Airport3:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/30/2025 10:40:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 3:10:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 28h 30m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/30/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/31/2025 11:10:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 18h 35m
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FlixBus20h 10m012:10 PMRomeTiburtina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/30/2025 12:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/31/2025 8:20:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 20h 10m
Cheapest Buses Tuesday
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/31/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 11:10:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 18h 35m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/31/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 12:10:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 18h 45m
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FlixBus19h 15m01:05 PMRomeAnagnina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/31/2025 1:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 8:20:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 19h 15m
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FlixBus20h 40m010:55 PMRomeTiburtina Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/31/2025 10:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 7:35:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 20h 40m
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FlixBus18h 10m09:30 AMRomeTiburtina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/31/2025 9:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 3:40:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 18h 10m
Cheapest Buses Wednesday
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 1/1/2026 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/2/2026 8:20:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 21h 35m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/1/2026 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/2/2026 11:10:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 18h 35m
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FlixBus18h 10m09:30 AMRomeTiburtina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/1/2026 9:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/2/2026 3:40:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 18h 10m
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FlixBus20h 10m012:15 AMRomeTiburtina Bus Station8:25 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/1/2026 12:15:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 8:25:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 20h 10m
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FlixBus19h 45m09:00 PMRomeTiburtina Bus Station4:45 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/1/2026 9:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/2/2026 4:45:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 19h 45m
Cheapest Buses Thursday
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BlaBlaCar12h 20m010:20 AMRome10:40 PMKarlsruhe0EconomyA Car from BlaBlaCar goes from , Rome (Italy) at 1/2/2026 10:20:00 AM to , Karlsruhe (Germany) arriving at 1/2/2026 10:40:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 12h 20m
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BlaBlaCar17h 0m09:40 AMRome2:40 AMKarlsruhe0EconomyA Car from BlaBlaCar goes from , Rome (Italy) at 1/2/2026 9:40:00 AM to , Karlsruhe (Germany) arriving at 1/3/2026 2:40:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 0m
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 1/2/2026 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 8:20:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 21h 35m
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FlixBus19h 30m010:40 AMRomeTiburtina Bus Station6:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/2/2026 10:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 6:10:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 19h 30m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/2/2026 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 11:10:00 AM. 50 Economy ticket for $175 per person are available. Travel duration is 18h 35m
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FlixBus20h 50m011:35 PMRomeAnagnina Bus Station8:25 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 1/2/2026 11:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 8:25:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 20h 50m
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FlixBus20h 40m010:55 PMRomeTiburtina Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/2/2026 10:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 7:35:00 PM. 50 Economy ticket for $184 per person are available. Travel duration is 20h 40m
Cheapest Carpool Friday
Cheapest Buses Friday
What are the fastest trips from Rome to Karlsruhe?
You can get to Karlsruhe from Rome in just 12h 20m with a Carpool from BlaBlaCar. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus17h 5m010:40 AMRomeTiburtina Bus Station3:45 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 10:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 3:45:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 17h 5m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 11:10:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 18h 35m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/27/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 12:10:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 18h 45m
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FlixBus20h 40m010:55 PMRomeTiburtina Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/27/2025 10:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 7:35:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 20h 40m
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/27/2025 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/28/2025 8:20:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 21h 35m
Fastest Buses Saturday
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FlixBus18h 10m09:30 AMRomeTiburtina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/28/2025 9:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 3:40:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 18h 10m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/28/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 11:10:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 18h 35m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/28/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 12:10:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 18h 45m
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FlixBus19h 45m09:00 PMRomeTiburtina Bus Station4:45 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/28/2025 9:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 4:45:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 19h 45m
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/28/2025 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/29/2025 8:20:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 21h 35m
Fastest Buses Sunday
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FlixBus17h 35m010:10 AMRomeTiburtina Bus Station3:45 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/29/2025 10:10:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 3:45:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 17h 35m
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FlixBus17h 45m09:25 AMRomeTiburtina Bus Station3:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/29/2025 9:25:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 3:10:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 17h 45m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/29/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 11:10:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 18h 35m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/29/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 12:10:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 18h 45m
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FlixBus24h 10m03:30 PMRome Ciampino AirportRome Ciampino Airport3:40 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/29/2025 3:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/30/2025 3:40:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 24h 10m
Fastest Buses Monday
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/30/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/31/2025 11:10:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 18h 35m
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FlixBus20h 10m012:10 PMRomeTiburtina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/30/2025 12:10:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/31/2025 8:20:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 20h 10m
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FlixBus20h 35m09:00 PMRomeTiburtina Bus Station5:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/30/2025 9:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 12/31/2025 5:35:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 20h 35m
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/30/2025 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 12/31/2025 8:20:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 21h 35m
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FlixBus28h 30m010:40 PMRome Ciampino AirportRome Ciampino Airport3:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/30/2025 10:40:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 3:10:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 28h 30m
Fastest Buses Tuesday
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FlixBus18h 10m09:30 AMRomeTiburtina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/31/2025 9:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 3:40:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 18h 10m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/31/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 11:10:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 18h 35m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/31/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 12:10:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 18h 45m
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FlixBus19h 15m01:05 PMRomeAnagnina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/31/2025 1:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 8:20:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 19h 15m
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FlixBus20h 40m010:55 PMRomeTiburtina Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/31/2025 10:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 7:35:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 20h 40m
Fastest Buses Wednesday
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FlixBus18h 10m09:30 AMRomeTiburtina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/1/2026 9:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/2/2026 3:40:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 18h 10m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/1/2026 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/2/2026 11:10:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 18h 35m
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FlixBus19h 45m09:00 PMRomeTiburtina Bus Station4:45 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/1/2026 9:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/2/2026 4:45:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 19h 45m
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FlixBus20h 10m012:15 AMRomeTiburtina Bus Station8:25 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/1/2026 12:15:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/1/2026 8:25:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 20h 10m
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 1/1/2026 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/2/2026 8:20:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 21h 35m
Fastest Buses Thursday
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BlaBlaCar12h 20m010:20 AMRome10:40 PMKarlsruhe0EconomyA Car from BlaBlaCar goes from , Rome (Italy) at 1/2/2026 10:20:00 AM to , Karlsruhe (Germany) arriving at 1/2/2026 10:40:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 12h 20m
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BlaBlaCar17h 0m09:40 AMRome2:40 AMKarlsruhe0EconomyA Car from BlaBlaCar goes from , Rome (Italy) at 1/2/2026 9:40:00 AM to , Karlsruhe (Germany) arriving at 1/3/2026 2:40:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 0m
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/2/2026 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 11:10:00 AM. 50 Economy ticket for $175 per person are available. Travel duration is 18h 35m
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FlixBus19h 30m010:40 AMRomeTiburtina Bus Station6:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/2/2026 10:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 6:10:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 19h 30m
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FlixBus20h 40m010:55 PMRomeTiburtina Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 1/2/2026 10:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 7:35:00 PM. 50 Economy ticket for $184 per person are available. Travel duration is 20h 40m
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FlixBus20h 50m011:35 PMRomeAnagnina Bus Station8:25 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 1/2/2026 11:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 8:25:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 20h 50m
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FlixBus21h 35m010:45 AMRome Ciampino AirportRome Ciampino Airport8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 1/2/2026 10:45:00 AM to Central Station, Karlsruhe (Germany) arriving at 1/3/2026 8:20:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 21h 35m
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Here you will find all operators and timetables for a
Bus from Rome to Karlsruhe
What are the most popular stations in Rome and Karlsruhe?
In Rome, you will usually depart from Termini Bus Station, Termini Central Station or Ostiense Train Station, while in Karlsruhe you will be arriving at Central Station, Heidehof Train Station or Tullastraße / Verkehrsbetriebe Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Karlsruhe from Rome? With 5 connections between 2 Bus and Carpool operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Karlsruhe, you can pay as low as $79 with a Carpool from BlaBlaCar.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Carpool from BlaBlaCar: you will get to Karlsruhe in just 12h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Karlsruhe are FlixBus and BlaBlaCar, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Karlsruhe is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Ettlingen, and look at flights from Rome Ciampino Airport, and landing at Karlsruhe/Baden-Baden Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Karlsruhe?
The most popular companies between Rome and Karlsruhe, are FlixBus and BlaBlaCar. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
All you need to know when you travel from Rome to Karlsruhe
Check all information on comfort and services on all modes of transports from Rome to Karlsruhe. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Karlsruhe
How can I reach Karlsruhe from Rome?
Every day, there are on average 5 connections between Bus and Carpool, with which you can get to Karlsruhe from Rome.
How far is Karlsruhe from Rome?
The distance between Rome and Karlsruhe is 529.5 miles.
What is the most ecofriendly mode of transport between Rome and Karlsruhe?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 23 kgs of CO2, a train 30 kgs, a car 145 kgs, and a flight 210 kgs.
What is the cheapest mode of transport from Rome to Karlsruhe?
You can get to Karlsruhe with just $79 by taking a Carpool from BlaBlaCar.
What is the fastest way to get from Rome to Karlsruhe?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Karlsruhe in just 12h 20m with a Carpool from BlaBlaCar.
More routes to Rome and to Karlsruhe
Looking for more options? Here you can see the most popular routes to Rome and to Karlsruhe. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Foggia to Rome
- Genoa to Rome
- Grottaminarda to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Palermo to Rome
- Perugia to Rome
- Pescara to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome
- Trips to Karlsruhe
- Amsterdam to Karlsruhe
- Antwerp to Karlsruhe
- Barcelona to Karlsruhe
- Berlin to Karlsruhe
- Braunschweig to Karlsruhe
- Brussels to Karlsruhe
- Chemnitz to Karlsruhe
- Dortmund to Karlsruhe
- Dusseldorf to Karlsruhe
- Frankfurt am Main Airport to Karlsruhe
- Frankfurt am Main to Karlsruhe
- Frankfurt Hahn Airport to Karlsruhe
- Freiburg to Karlsruhe
- Kehl to Karlsruhe
- Ludwigshafen to Karlsruhe
- Mannheim to Karlsruhe
- Milan to Karlsruhe
- Munich to Karlsruhe
- Paris to Karlsruhe
- Poznan to Karlsruhe
- Stuttgart Airport to Karlsruhe
- Stuttgart to Karlsruhe
- Vienna to Karlsruhe
- Zurich to Karlsruhe
