Bus from Rome to Karlsruhe from $90

Compare all the bus companies and find the best price with CheckMyBus
1
Search accommodation with Booking.com
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Rome to Karlsruhe

Here is a selection of the cheapest bus trips from the schedule from Rome to Karlsruhe from various bus operators like FlixBus or MarinoBus for the next days.

today
from $90
tomorrow
from $96
Saturday
from $94
Sunday
from $140
Monday
from $100
Tuesday
from $96
Wednesday
from $90

Cheapest bus trips today

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 35m 4:35 PM Rome Tiburtina Bus Station 11:10 AM Karlsruhe Central Station  Economy $90
FlixBus 17h 35m 10:10 AM Rome Tiburtina Bus Station 3:45 AM Karlsruhe Central Station  Economy $106
FlixBus 20h 10m 7:30 AM Rome Anagnina Bus Station 3:40 AM Karlsruhe Central Station  Economy $106
FlixBus 18h 10m 9:30 AM Rome Tiburtina Bus Station 3:40 AM Karlsruhe Central Station  Economy $108
FlixBus 17h 45m 9:25 AM Rome Tiburtina Bus Station 3:10 AM Karlsruhe Central Station  Economy $109
  • Did you know that if you travel from Rome to Karlsruhe via Bologna, you can save more than $12? You can find the corresponding connections below.
    • Distribusion
      23h 10m
      0
      12:00 PM
      Rome
      Tiburtina Bus Station
      5:15 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      Distribusion
      Premium Economy
      $9
    • Waiting Time 4h 45m
    • FlixBus
      13h 10m
      0
      10:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      11:10 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $69
    Travel time is 5h 35m longer, but you will save $12

Cheapest bus trips tomorrow

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 35m 4:35 PM Rome Tiburtina Bus Station 11:10 AM Karlsruhe Central Station  Economy $96
FlixBus 19h 15m 8:00 PM Rome Tiburtina Bus Station 3:15 PM Karlsruhe Central Station  Economy $117
FlixBus 20h 10m 12:15 AM Rome Tiburtina Bus Station 8:25 PM Karlsruhe Central Station  Economy $119
FlixBus 17h 45m 9:25 AM Rome Tiburtina Bus Station 3:10 AM Karlsruhe Central Station  Economy $121
FlixBus 17h 35m 10:10 AM Rome Tiburtina Bus Station 3:45 AM Karlsruhe Central Station  Economy $121
  • Did you know that if you travel from Rome to Karlsruhe via Bologna, you can save more than $18? You can find the corresponding connections below.
    • Distribusion
      23h 10m
      0
      12:00 PM
      Rome
      Tiburtina Bus Station
      5:15 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      Distribusion
      Premium Economy
      $9
    • Waiting Time 4h 45m
    • FlixBus
      13h 10m
      0
      10:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      11:10 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $69
    Travel time is 5h 35m longer, but you will save $18

Cheapest bus trips Saturday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 35m 4:35 PM Rome Tiburtina Bus Station 11:10 AM Karlsruhe Central Station  Economy $94
FlixBus 18h 10m 9:30 AM Rome Tiburtina Bus Station 3:40 AM Karlsruhe Central Station  Economy $113
FlixBus 20h 10m 7:30 AM Rome Anagnina Bus Station 3:40 AM Karlsruhe Central Station  Economy $113
FlixBus 20h 40m 10:55 PM Rome Tiburtina Bus Station 7:35 PM Karlsruhe Central Station  Economy $115
FlixBus 19h 15m 1:05 PM Rome Anagnina Bus Station 8:20 AM Karlsruhe Central Station  Economy $120
  • Did you know that if you travel from Rome to Karlsruhe via Bologna, you can save more than $16? You can find the corresponding connections below.
    • Distribusion
      23h 10m
      0
      12:00 PM
      Rome
      Tiburtina Bus Station
      5:15 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      Distribusion
      Premium Economy
      $9
    • Waiting Time 4h 45m
    • FlixBus
      13h 10m
      0
      10:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      11:10 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $69
    Travel time is 5h 0m longer, but you will save $16

Cheapest bus trips Sunday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 10m 9:30 AM Rome Tiburtina Bus Station 3:40 AM Karlsruhe Central Station  Economy $140
FlixBus 18h 45m 5:25 PM Rome Anagnina Bus Station 12:10 PM Karlsruhe Central Station  Economy $141
FlixBus 17h 5m 10:40 AM Rome Tiburtina Bus Station 3:45 AM Karlsruhe Central Station  Economy $143
FlixBus 20h 10m 7:30 AM Rome Anagnina Bus Station 3:40 AM Karlsruhe Central Station  Economy $143
FlixBus 17h 55m 9:45 PM Rome Tiburtina Bus Station 3:40 PM Karlsruhe Central Station  Economy $144
  • Did you know that if you travel from Rome to Karlsruhe via Bologna, you can save more than $68? You can find the corresponding connections below.
    • FlixBus
      22h 25m
      0
      12:45 PM
      Rome
      Anagnina Bus Station
      5:35 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      FlixBus
      Economy
      $11
    • Waiting Time 4h 25m
    • FlixBus
      13h 10m
      0
      10:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      11:10 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $61
    Travel time is 5h 20m longer, but you will save $68

Cheapest bus trips Monday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 35m 4:35 PM Rome Tiburtina Bus Station 11:10 AM Karlsruhe Central Station  Economy $100
FlixBus 19h 45m 9:00 PM Rome Tiburtina Bus Station 4:45 PM Karlsruhe Central Station  Economy $113
FlixBus 20h 10m 7:30 AM Rome Anagnina Bus Station 3:40 AM Karlsruhe Central Station  Economy $122
FlixBus 18h 45m 5:25 PM Rome Anagnina Bus Station 12:10 PM Karlsruhe Central Station  Economy $124
FlixBus 18h 10m 9:30 AM Rome Tiburtina Bus Station 3:40 AM Karlsruhe Central Station  Economy $128
  • Did you know that if you travel from Rome to Karlsruhe via Bologna, you can save more than $33? You can find the corresponding connections below.
    • FlixBus
      26h 20m
      0
      8:50 AM
      Rome
      Tiburtina Bus Station
      2:15 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      FlixBus
      Economy
      $14
    • Waiting Time 7h 45m
    • FlixBus
      13h 10m
      0
      10:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      11:10 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $53
    Travel time is 8h 10m longer, but you will save $33

Cheapest bus trips Tuesday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 35m 4:35 PM Rome Tiburtina Bus Station 11:10 AM Karlsruhe Central Station  Economy $96
FlixBus 20h 35m 9:00 PM Rome Tiburtina Bus Station 5:35 PM Karlsruhe Central Station  Economy $102
FlixBus 18h 10m 9:30 AM Rome Tiburtina Bus Station 3:40 AM Karlsruhe Central Station  Economy $106
MarinoBus 18h 5m 11:00 PM Rome Tiburtina Bus Station 5:05 PM Karlsruhe Central Station  Basic $128
  • Did you know that if you travel from Rome to Karlsruhe via Bologna, you can save more than $29? You can find the corresponding connections below.
    • FlixBus
      26h 20m
      0
      8:50 AM
      Rome
      Tiburtina Bus Station
      2:15 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      FlixBus
      Economy
      $14
    • Waiting Time 7h 45m
    • FlixBus
      13h 10m
      0
      10:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      11:10 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $53
    Travel time is 8h 15m longer, but you will save $29

Cheapest bus trips Wednesday

Prices are for one way and one person
Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 35m 4:35 PM Rome Tiburtina Bus Station 11:10 AM Karlsruhe Central Station  Economy $90
FlixBus 18h 10m 9:30 AM Rome Tiburtina Bus Station 3:40 AM Karlsruhe Central Station  Economy $101
FlixBus 20h 10m 7:30 AM Rome Anagnina Bus Station 3:40 AM Karlsruhe Central Station  Economy $102
FlixBus 17h 35m 10:10 AM Rome Tiburtina Bus Station 3:45 AM Karlsruhe Central Station  Economy $103
FlixBus 19h 15m 1:05 PM Rome Anagnina Bus Station 8:20 AM Karlsruhe Central Station  Economy $106
  • Did you know that if you travel from Rome to Karlsruhe via Bologna, you can save more than $23? You can find the corresponding connections below.
    • FlixBus
      26h 20m
      0
      8:50 AM
      Rome
      Tiburtina Bus Station
      2:15 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      FlixBus
      Economy
      $14
    • Waiting Time 7h 45m
    • FlixBus
      13h 10m
      0
      10:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      11:10 AM
      Karlsruhe
      Central Station
      0
      FlixBus
      Economy
      $53
    Travel time is 8h 45m longer, but you will save $23

Frequency of bus connections between Rome and Karlsruhe

See here how frequent the connections between Rome and Karlsruhe are, during different times and days of the week.
Thursday is the busiest day, with more than 15 daily buses from Rome to Karlsruhe. Monday has instead the fewest connections, with only 11 daily coaches between Rome and Karlsruhe.
The busiest time of the day is the Morning, with 30 buses from Rome to Karlsruhe, while Night sees the fewest connections between Rome and Karlsruhe, with 5 offers.

Facts about the bus from Rome to Karlsruhe

Compare all providers like FlixBus and MarinoBus that travel 13 times every day by bus from Rome to Karlsruhe in one click! Book your bus ticket from Rome to Karlsruhe starting from $90!

Cheapest Bus $90
Fastest Bus 17h 5m
Earliest Bus 12:15 AM
Latest Bus 11:50 PM
Daily Bus Routes 13 Ø
Distance 529.5 miles
Bus Companies FlixBus and MarinoBus

Cheapest bus connections from Rome to Karlsruhe

Every day, 13 buses from 2 bus companies leave Rome for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/31/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/27
Monday 07/28
Tuesday 07/29
Wednesday 07/30
Thursday 07/31
$90
Friday 08/01
$96
Saturday 08/02
$94
Sunday 08/03
$135
Monday 08/04
$100
Tuesday 08/05
$96
Wednesday 08/06
$90
Thursday 08/07
$88
Friday 08/08
$96
Saturday 08/09
$128
Sunday 08/10
$105
Monday 08/11
$101
Tuesday 08/12
$94
Wednesday 08/13
$96
Thursday 08/14
$114
Friday 08/15
$109
Saturday 08/16
$112
Sunday 08/17
$116
Monday 08/18
$92
Tuesday 08/19
$88
Wednesday 08/20
$89
Thursday 08/21
$86
Friday 08/22
$100
Saturday 08/23

The cheapest time to travel from Rome to Karlsruhe

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Karlsruhe, for the next 30 days.
With a price starting from $90, Wednesday is the cheapest day for a bus from Rome to Karlsruhe. Sunday instead is the most expensive day with prices starting from $140.
Afternoon is the cheapest day time for bus tickets from Rome to Karlsruhe, with $90. Night is the most expensive time of the day with prices starting from $110.

How to save money travelling from Rome to Karlsruhe

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Karlsruhe are also emptier.

All bus stations and stops in Rome and Karlsruhe

In the map below, you can see where to find all bus stations in Rome and Karlsruhe.

Service and Comfort on the bus from Rome to Karlsruhe

Want to know which seat classes are available on the buses from Rome to Karlsruhe? Or which bus companies serve the route Rome to Karlsruhe? Below you will find answers to your questions.

FAQs about the Rome to Karlsruhe bus

How much does a Rome Karlsruhe bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $90 and takes 18h 35m to reach Karlsruhe. Compare offers to save money!

How much could I save by comparing buses from Rome to Karlsruhe?

This route is offered by 2 companies with a range of ticket prices between $90 and $182. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Karlsruhe.

On average, how many connections are available from Rome to Karlsruhe each day?

Every day, the Rome to Karlsruhe bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Karlsruhe take?

The fastest bus from Rome to Karlsruhe is offered by FlixBus and takes 17h 5m. Bus tickets for this connection cost $125. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Karlsruhe?

The earliest bus arriving in Karlsruhe from Rome starts at 12:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Karlsruhe?

The latest bus trip departing from Rome for Karlsruhe starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Karlsruhe route?

When traveling by bus from Rome to Karlsruhe, passengers can travel with FlixBus and MarinoBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Karlsruhe?

You can check all the direct connections between Rome and Karlsruhe by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and MarinoBus.

What can I take with me on the Rome to Karlsruhe bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Karlsruhe bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Karlsruhe bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Karlsruhe on your planned travel date.

Available seat classes which are offered on the bus route Rome to Karlsruhe

Basic
Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Karlsruhe

Here’s an overview of the most popular bus routes to Rome and to Karlsruhe. Simply click on the connection of your choice, and you will find all the details about your bus route!

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.