Bus from Rome to Karlsruhe from $65

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Compare all timetables for the bus from Rome to Karlsruhe

Here is a selection of the cheapest bus trips from the schedule from Rome to Karlsruhe from various bus operators like FlixBus for the next days.

today
from $73
tomorrow
from $65
Thursday
from $65
Friday
from $93
Saturday
from $84
Sunday
from $96
Monday
from $77

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    19h 35m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    12:10 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $73
  • FlixBus
    20h 35m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    5:35 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $85
  • FlixBus
    20h 10m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    3:40 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $90
  • FlixBus
    18h 45m
    0
    5:25 PM
    Rome
    Anagnina Bus Station
    12:10 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $97
  • FlixBus
    17h 35m
    0
    10:10 AM
    Rome
    Tiburtina Bus Station
    3:45 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $97

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    19h 35m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    12:10 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    18h 10m
    0
    9:30 AM
    Rome
    Tiburtina Bus Station
    3:40 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $83
  • FlixBus
    18h 45m
    0
    5:25 PM
    Rome
    Anagnina Bus Station
    12:10 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $84
  • FlixBus
    19h 15m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    8:20 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $88
  • FlixBus
    17h 55m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    3:40 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $88

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    18h 35m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    11:10 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    20h 10m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    3:40 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $74
  • FlixBus
    18h 10m
    0
    9:30 AM
    Rome
    Tiburtina Bus Station
    3:40 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $75
  • FlixBus
    18h 45m
    0
    5:25 PM
    Rome
    Anagnina Bus Station
    12:10 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $75
  • FlixBus
    17h 45m
    0
    9:25 AM
    Rome
    Tiburtina Bus Station
    3:10 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $80

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    18h 35m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    11:10 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $93
  • FlixBus
    22h 15m
    0
    5:25 PM
    Rome
    Anagnina Bus Station
    3:40 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $106
  • FlixBus
    17h 55m
    0
    9:45 PM
    Rome
    Tiburtina Bus Station
    3:40 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $110
  • FlixBus
    17h 35m
    0
    10:10 AM
    Rome
    Tiburtina Bus Station
    3:45 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $115
  • FlixBus
    19h 15m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    8:20 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $115

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    18h 35m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    11:10 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $84
  • FlixBus
    20h 40m
    0
    10:55 PM
    Rome
    Tiburtina Bus Station
    7:35 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $110
  • FlixBus
    19h 15m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    8:20 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $110
  • FlixBus
    20h 10m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    3:40 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $117
  • FlixBus
    19h 15m
    0
    8:00 PM
    Rome
    Tiburtina Bus Station
    3:15 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $118

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    18h 35m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    11:10 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $96
  • FlixBus
    17h 45m
    0
    9:25 AM
    Rome
    Tiburtina Bus Station
    3:10 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $127
  • FlixBus
    20h 10m
    0
    12:15 AM
    Rome
    Tiburtina Bus Station
    8:25 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $134
  • FlixBus
    17h 5m
    0
    10:40 AM
    Rome
    Tiburtina Bus Station
    3:45 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $135
  • FlixBus
    19h 15m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    8:20 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $135

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    18h 35m
    0
    4:35 PM
    Rome
    Tiburtina Bus Station
    11:10 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $77
  • FlixBus
    19h 45m
    0
    9:00 PM
    Rome
    Tiburtina Bus Station
    4:45 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $88
  • FlixBus
    18h 45m
    0
    5:25 PM
    Rome
    Anagnina Bus Station
    12:10 PM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $89
  • FlixBus
    20h 10m
    0
    7:30 AM
    Rome
    Anagnina Bus Station
    3:40 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $92
  • FlixBus
    19h 15m
    0
    1:05 PM
    Rome
    Anagnina Bus Station
    8:20 AM
    Karlsruhe
    Central Station
    0
    FlixBus
    Economy
    $92

Frequency of bus connections between Rome and Karlsruhe

See here how frequent the connections between Rome and Karlsruhe are, during different times and days of the week.
Thursday is the busiest day, with more than 15 daily buses from Rome to Karlsruhe. Tuesday has instead the fewest connections, with only 10 daily coaches between Rome and Karlsruhe.
The busiest time of the day is the Morning, with 30 buses from Rome to Karlsruhe, while Night sees the fewest connections between Rome and Karlsruhe, with 5 offers.

Facts about the bus from Rome to Karlsruhe

Compare all providers like FlixBus that travel 13 times every day by bus from Rome to Karlsruhe in one click! Book your bus ticket from Rome to Karlsruhe starting from $65!

Cheapest Bus $65
Fastest Bus 17h 5m
Earliest Bus 7:30 AM
Latest Bus 9:00 PM
Daily Bus Routes 13 Ø
Distance 529.5 miles
Bus Companies FlixBus

Cheapest bus connections from Rome to Karlsruhe

Every day, 13 buses from 1 bus companies leave Rome for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/08/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/06
Monday 07/07
Tuesday 07/08
$73
Wednesday 07/09
$65
Thursday 07/10
$65
Friday 07/11
$93
Saturday 07/12
$84
Sunday 07/13
$96
Monday 07/14
$77
Tuesday 07/15
$65
Wednesday 07/16
$67
Thursday 07/17
$61
Friday 07/18
$88
Saturday 07/19
$75
Sunday 07/20
$84
Monday 07/21
$67
Tuesday 07/22
$69
Wednesday 07/23
$70
Thursday 07/24
$69
Friday 07/25
$89
Saturday 07/26
$77
Sunday 07/27
Monday 07/28
$80
Tuesday 07/29
$76
Wednesday 07/30
$80
Thursday 07/31
$77
Friday 08/01
$86
Saturday 08/02

The cheapest time to travel from Rome to Karlsruhe

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Karlsruhe, for the next 30 days.
With a price starting from $65, Wednesday is the cheapest day for a bus from Rome to Karlsruhe. Sunday instead is the most expensive day with prices starting from $96.
Afternoon is the cheapest day time for bus tickets from Rome to Karlsruhe, with $65. Night is the most expensive time of the day with prices starting from $92.

How to save money travelling from Rome to Karlsruhe

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Karlsruhe are also emptier.

All bus stations and stops in Rome and Karlsruhe

In the map below, you can see where to find all bus stations in Rome and Karlsruhe.

Service and Comfort on the bus from Rome to Karlsruhe

Want to know which seat classes are available on the buses from Rome to Karlsruhe? Or which bus companies serve the route Rome to Karlsruhe? Below you will find answers to your questions.

FAQs about the Rome to Karlsruhe bus

How much does a Rome Karlsruhe bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $65 and takes 19h 35m to reach Karlsruhe. Compare offers to save money!

How much could I save by comparing buses from Rome to Karlsruhe?

This route is offered by 1 companies with a range of ticket prices between $65 and $160. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Karlsruhe.

On average, how many connections are available from Rome to Karlsruhe each day?

Every day, the Rome to Karlsruhe bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Karlsruhe take?

The fastest bus from Rome to Karlsruhe is offered by FlixBus and takes 17h 5m. Bus tickets for this connection cost $128. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Karlsruhe?

The earliest bus arriving in Karlsruhe from Rome starts at 7:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Karlsruhe?

The latest bus trip departing from Rome for Karlsruhe starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Karlsruhe route?

When traveling by bus from Rome to Karlsruhe, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Karlsruhe?

You can check all the direct connections between Rome and Karlsruhe by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Karlsruhe bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Karlsruhe bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Karlsruhe bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Karlsruhe on your planned travel date.

Available seat classes which are offered on the bus route Rome to Karlsruhe

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Karlsruhe

Here’s an overview of the most popular bus routes to Rome and to Karlsruhe. Simply click on the connection of your choice, and you will find all the details about your bus route!

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