Compare all timetables for the bus from Rome to Karlsruhe
Cheapest bus trips today
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FlixBus19h 35m04:35 PMRomeTiburtina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/8/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/9/2025 12:10:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 19h 35m
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FlixBus20h 35m09:00 PMRomeTiburtina Bus Station5:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/8/2025 9:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/9/2025 5:35:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 35m
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FlixBus20h 10m07:30 AMRomeAnagnina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/8/2025 7:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/9/2025 3:40:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 20h 10m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/8/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/9/2025 12:10:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 18h 45m
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FlixBus17h 35m010:10 AMRomeTiburtina Bus Station3:45 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/8/2025 10:10:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/9/2025 3:45:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 17h 35m
Cheapest bus trips tomorrow
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FlixBus19h 35m04:35 PMRomeTiburtina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/9/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/10/2025 12:10:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 19h 35m
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FlixBus18h 10m09:30 AMRomeTiburtina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/9/2025 9:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/10/2025 3:40:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 18h 10m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/9/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/10/2025 12:10:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 18h 45m
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FlixBus19h 15m01:05 PMRomeAnagnina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/9/2025 1:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/10/2025 8:20:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 15m
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FlixBus17h 55m09:45 PMRomeTiburtina Bus Station3:40 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/9/2025 9:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/10/2025 3:40:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 17h 55m
Cheapest bus trips Thursday
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/10/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/11/2025 11:10:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 18h 35m
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FlixBus20h 10m07:30 AMRomeAnagnina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/10/2025 7:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/11/2025 3:40:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 20h 10m
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FlixBus18h 10m09:30 AMRomeTiburtina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/10/2025 9:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/11/2025 3:40:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 18h 10m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/10/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/11/2025 12:10:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 18h 45m
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FlixBus17h 45m09:25 AMRomeTiburtina Bus Station3:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/10/2025 9:25:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/11/2025 3:10:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 17h 45m
Cheapest bus trips Friday
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/11/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/12/2025 11:10:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 18h 35m
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FlixBus22h 15m05:25 PMRomeAnagnina Bus Station3:40 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/11/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/12/2025 3:40:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 22h 15m
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FlixBus17h 55m09:45 PMRomeTiburtina Bus Station3:40 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/11/2025 9:45:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/12/2025 3:40:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 17h 55m
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FlixBus17h 35m010:10 AMRomeTiburtina Bus Station3:45 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/11/2025 10:10:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/12/2025 3:45:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 17h 35m
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FlixBus19h 15m01:05 PMRomeAnagnina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/11/2025 1:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/12/2025 8:20:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 19h 15m
Cheapest bus trips Saturday
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/12/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/13/2025 11:10:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 18h 35m
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FlixBus20h 40m010:55 PMRomeTiburtina Bus Station7:35 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/12/2025 10:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/13/2025 7:35:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 20h 40m
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FlixBus19h 15m01:05 PMRomeAnagnina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/12/2025 1:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/13/2025 8:20:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 19h 15m
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FlixBus20h 10m07:30 AMRomeAnagnina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/12/2025 7:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/13/2025 3:40:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 20h 10m
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FlixBus19h 15m08:00 PMRomeTiburtina Bus Station3:15 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/12/2025 8:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/13/2025 3:15:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 19h 15m
Cheapest bus trips Sunday
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/13/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/14/2025 11:10:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 18h 35m
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FlixBus17h 45m09:25 AMRomeTiburtina Bus Station3:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/13/2025 9:25:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/14/2025 3:10:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 17h 45m
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FlixBus20h 10m012:15 AMRomeTiburtina Bus Station8:25 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/13/2025 12:15:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/13/2025 8:25:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 20h 10m
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FlixBus17h 5m010:40 AMRomeTiburtina Bus Station3:45 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/13/2025 10:40:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/14/2025 3:45:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 17h 5m
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FlixBus19h 15m01:05 PMRomeAnagnina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/13/2025 1:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/14/2025 8:20:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 19h 15m
Cheapest bus trips Monday
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FlixBus18h 35m04:35 PMRomeTiburtina Bus Station11:10 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/14/2025 4:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/15/2025 11:10:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 18h 35m
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FlixBus19h 45m09:00 PMRomeTiburtina Bus Station4:45 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/14/2025 9:00:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/15/2025 4:45:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 45m
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FlixBus18h 45m05:25 PMRomeAnagnina Bus Station12:10 PMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/14/2025 5:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/15/2025 12:10:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 45m
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FlixBus20h 10m07:30 AMRomeAnagnina Bus Station3:40 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/14/2025 7:30:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/15/2025 3:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 20h 10m
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FlixBus19h 15m01:05 PMRomeAnagnina Bus Station8:20 AMKarlsruheCentral Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 7/14/2025 1:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/15/2025 8:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 19h 15m
Frequency of bus connections between Rome and Karlsruhe
Facts about the bus from Rome to Karlsruhe
Compare all providers like FlixBus that travel 13 times every day by bus from Rome to Karlsruhe in one click! Book your bus ticket from Rome to Karlsruhe starting from $65!
Cheapest Bus | $65 |
Fastest Bus | 17h 5m |
Earliest Bus | 7:30 AM |
Latest Bus | 9:00 PM |
Daily Bus Routes | 13 Ø |
Distance | 529.5 miles |
Bus Companies | FlixBus |
Cheapest bus connections from Rome to Karlsruhe
Every day, 13 buses from 1 bus companies leave Rome for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/08/2025 and for the following days.
The cheapest time to travel from Rome to Karlsruhe
How to save money travelling from Rome to Karlsruhe
Book the ticket from Rome to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Karlsruhe are also emptier.All bus stations and stops in Rome and Karlsruhe
In the map below, you can see where to find all bus stations in Rome and Karlsruhe.
Service and Comfort on the bus from Rome to Karlsruhe
FAQs about the Rome to Karlsruhe bus
How much does a Rome Karlsruhe bus trip cost?
How much could I save by comparing buses from Rome to Karlsruhe?
On average, how many connections are available from Rome to Karlsruhe each day?
How long does a bus journey from Rome to Karlsruhe take?
What time is the first bus from Rome to Karlsruhe?
What time is the last bus from Rome to Karlsruhe?
Which bus companies operate the Rome Karlsruhe route?
Is there a direct bus between Rome and Karlsruhe?
What can I take with me on the Rome to Karlsruhe bus route?
What equipment is available for the Rome Karlsruhe bus route?
Available seat classes which are offered on the bus route Rome to Karlsruhe
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Rome and to Karlsruhe
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