What is the best way to travel from Santander to Madrid?
Looking for a trip? Compare all the available Flights, Carpool and Buses for the journey to Madrid from Santander. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Madrid from Santander?
You can get to Madrid with just $22 by taking a Flight from Air Nostrum, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/29/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 5/29/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/29/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/29/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA6h 15m010:30 AMSantanderBus Station4:45 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/29/2026 10:30:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/29/2026 4:45:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 6h 15m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 5/29/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/30/2026 1:20:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 30m
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Iberia1h 10m09:35 PMSantander AirportSantander Airport10:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/29/2026 9:35:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/29/2026 10:45:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m09:35 PMSantander AirportSantander Airport10:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 5/29/2026 9:35:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/29/2026 10:45:00 PM. 50 Economy ticket for $327 per person are available. Travel duration is 1h 10m
Cheapest Buses Friday
Cheapest Flights Friday
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Air Nostrum1h 10m09:35 PMSantander AirportSantander Airport10:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 5/30/2026 9:35:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/30/2026 10:45:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 1h 10m
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Iberia1h 10m09:35 PMSantander AirportSantander Airport10:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/30/2026 9:35:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/30/2026 10:45:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 10m
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Iberia1h 10m09:20 AMSantander AirportSantander Airport10:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/30/2026 9:20:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/30/2026 10:30:00 AM. 50 Economy ticket for $374 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 5/30/2026 5:40:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/30/2026 6:50:00 PM. 50 Economy ticket for $376 per person are available. Travel duration is 1h 10m
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BlaBlaCar5h 4m09:30 AMSantander Airport2:40 PMMadrid0EconomyA Car from BlaBlaCar goes from , Santander Airport (Spain) at 5/30/2026 9:30:00 AM to , Madrid (Spain) arriving at 5/30/2026 2:40:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 4m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/30/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 5/30/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/30/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/30/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/30/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/30/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 5/30/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/31/2026 1:20:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 30m
Cheapest Flights Saturday
Cheapest Carpool Saturday
Cheapest Buses Saturday
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/31/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 5/31/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/31/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/31/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/31/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/31/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 5/31/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/1/2026 1:20:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 18h 30m
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Iberia1h 10m09:20 AMSantander AirportSantander Airport10:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/31/2026 9:20:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/31/2026 10:30:00 AM. 50 Economy ticket for $259 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m09:20 AMSantander AirportSantander Airport10:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 5/31/2026 9:20:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/31/2026 10:30:00 AM. 50 Economy ticket for $363 per person are available. Travel duration is 1h 10m
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/31/2026 5:40:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/31/2026 6:50:00 PM. 50 Economy ticket for $379 per person are available. Travel duration is 1h 10m
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/31/2026 5:40:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/31/2026 6:50:00 PM. 50 Economy ticket for $446 per person are available. Travel duration is 1h 10m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/1/2026 5:40:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/1/2026 6:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 1h 10m
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Iberia1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/1/2026 6:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/1/2026 7:40:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/1/2026 10:05:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/1/2026 11:15:00 AM. 50 Economy ticket for $268 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/1/2026 6:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/1/2026 7:40:00 AM. 50 Economy ticket for $383 per person are available. Travel duration is 1h 10m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/1/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 6/1/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/1/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/1/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/1/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/1/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 6/1/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/2/2026 1:20:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 18h 30m
Cheapest Flights Monday
Cheapest Buses Monday
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/2/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 6/2/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/2/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/2/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/2/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/2/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 6/2/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/3/2026 1:20:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 18h 30m
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Iberia1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/2/2026 10:05:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/2/2026 11:15:00 AM. 50 Economy ticket for $257 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/2/2026 10:05:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/2/2026 11:15:00 AM. 50 Economy ticket for $317 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/2/2026 6:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/2/2026 7:40:00 AM. 50 Economy ticket for $319 per person are available. Travel duration is 1h 10m
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Iberia1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/2/2026 6:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/2/2026 7:40:00 AM. 50 Economy ticket for $379 per person are available. Travel duration is 1h 10m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/3/2026 5:40:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/3/2026 6:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 1h 10m
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Iberia1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/3/2026 6:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/3/2026 7:40:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 1h 10m
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/3/2026 5:40:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/3/2026 6:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/3/2026 6:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/3/2026 7:40:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 1h 10m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/3/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 6/3/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/3/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/3/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/3/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/3/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 6/3/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/4/2026 1:20:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 18h 30m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
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ALSA5h 45m012:45 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/4/2026 12:45:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/4/2026 6:30:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 5h 45m
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ALSA6h 15m010:30 AMSantanderBus Station4:45 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/4/2026 10:30:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/4/2026 4:45:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 6h 15m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/4/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/4/2026 11:00:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 30m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 6/4/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/5/2026 1:20:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 18h 30m
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Iberia1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/4/2026 10:05:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/4/2026 11:15:00 AM. 50 Economy ticket for $287 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/4/2026 6:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/4/2026 7:40:00 AM. 50 Economy ticket for $313 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/4/2026 10:05:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/4/2026 11:15:00 AM. 50 Economy ticket for $369 per person are available. Travel duration is 1h 10m
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Iberia1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/4/2026 6:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/4/2026 7:40:00 AM. 50 Economy ticket for $374 per person are available. Travel duration is 1h 10m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Santander to Madrid?
You can get to Madrid from Santander in just 1h 10m with a Flight from Iberia. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Iberia1h 10m09:35 PMSantander AirportSantander Airport10:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/29/2026 9:35:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/29/2026 10:45:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m09:35 PMSantander AirportSantander Airport10:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 5/29/2026 9:35:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/29/2026 10:45:00 PM. 50 Economy ticket for $327 per person are available. Travel duration is 1h 10m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/29/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/29/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA6h 15m010:30 AMSantanderBus Station4:45 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/29/2026 10:30:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/29/2026 4:45:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 6h 15m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/29/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 5/29/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 5/29/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/30/2026 1:20:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 30m
Fastest Flights Friday
Fastest Buses Friday
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Air Nostrum1h 10m09:35 PMSantander AirportSantander Airport10:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 5/30/2026 9:35:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/30/2026 10:45:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 1h 10m
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Iberia1h 10m09:35 PMSantander AirportSantander Airport10:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/30/2026 9:35:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/30/2026 10:45:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 10m
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Iberia1h 10m09:20 AMSantander AirportSantander Airport10:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/30/2026 9:20:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/30/2026 10:30:00 AM. 50 Economy ticket for $374 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 5/30/2026 5:40:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/30/2026 6:50:00 PM. 50 Economy ticket for $376 per person are available. Travel duration is 1h 10m
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BlaBlaCar5h 4m09:30 AMSantander Airport2:40 PMMadrid0EconomyA Car from BlaBlaCar goes from , Santander Airport (Spain) at 5/30/2026 9:30:00 AM to , Madrid (Spain) arriving at 5/30/2026 2:40:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 4m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/30/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/30/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/30/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/30/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/30/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 5/30/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 5/30/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/31/2026 1:20:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 30m
Fastest Flights Saturday
Fastest Carpool Saturday
Fastest Buses Saturday
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Iberia1h 10m09:20 AMSantander AirportSantander Airport10:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/31/2026 9:20:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/31/2026 10:30:00 AM. 50 Economy ticket for $259 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m09:20 AMSantander AirportSantander Airport10:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 5/31/2026 9:20:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/31/2026 10:30:00 AM. 50 Economy ticket for $363 per person are available. Travel duration is 1h 10m
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/31/2026 5:40:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/31/2026 6:50:00 PM. 50 Economy ticket for $379 per person are available. Travel duration is 1h 10m
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 5/31/2026 5:40:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 5/31/2026 6:50:00 PM. 50 Economy ticket for $446 per person are available. Travel duration is 1h 10m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/31/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/31/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/31/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 5/31/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 5/31/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 5/31/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 5/31/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/1/2026 1:20:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 18h 30m
Fastest Flights Sunday
Fastest Buses Sunday
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/1/2026 5:40:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/1/2026 6:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 1h 10m
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Iberia1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/1/2026 6:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/1/2026 7:40:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/1/2026 10:05:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/1/2026 11:15:00 AM. 50 Economy ticket for $268 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/1/2026 6:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/1/2026 7:40:00 AM. 50 Economy ticket for $383 per person are available. Travel duration is 1h 10m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/1/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/1/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/1/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/1/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/1/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 6/1/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 6/1/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/2/2026 1:20:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 18h 30m
Fastest Flights Monday
Fastest Buses Monday
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Iberia1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/2/2026 10:05:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/2/2026 11:15:00 AM. 50 Economy ticket for $257 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/2/2026 10:05:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/2/2026 11:15:00 AM. 50 Economy ticket for $317 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/2/2026 6:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/2/2026 7:40:00 AM. 50 Economy ticket for $319 per person are available. Travel duration is 1h 10m
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Iberia1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/2/2026 6:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/2/2026 7:40:00 AM. 50 Economy ticket for $379 per person are available. Travel duration is 1h 10m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/2/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/2/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/2/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/2/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/2/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 6/2/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 6/2/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/3/2026 1:20:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 18h 30m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/3/2026 5:40:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/3/2026 6:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 1h 10m
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Iberia1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/3/2026 6:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/3/2026 7:40:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 1h 10m
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Iberia1h 10m05:40 PMSantander AirportSantander Airport6:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/3/2026 5:40:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/3/2026 6:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/3/2026 6:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/3/2026 7:40:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 1h 10m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/3/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/3/2026 11:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 30m
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ALSA5h 30m01:00 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/3/2026 1:00:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/3/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 30m
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ALSA6h 45m04:00 PMSantanderBus Station10:45 PMMadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/3/2026 4:00:00 PM to Intercambiador de Moncloa, Madrid (Spain) arriving at 6/3/2026 10:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 6/3/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/4/2026 1:20:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 18h 30m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Iberia1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/4/2026 10:05:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/4/2026 11:15:00 AM. 50 Economy ticket for $287 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/4/2026 6:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/4/2026 7:40:00 AM. 50 Economy ticket for $313 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m010:05 AMSantander AirportSantander Airport11:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 6/4/2026 10:05:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/4/2026 11:15:00 AM. 50 Economy ticket for $369 per person are available. Travel duration is 1h 10m
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Iberia1h 10m06:30 AMSantander AirportSantander Airport7:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 6/4/2026 6:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 6/4/2026 7:40:00 AM. 50 Economy ticket for $374 per person are available. Travel duration is 1h 10m
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ALSA5h 30m05:30 PMSantanderBus Station11:00 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/4/2026 5:30:00 PM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/4/2026 11:00:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 30m
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ALSA5h 45m012:45 AMSantanderBus Station6:30 AMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/4/2026 12:45:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/4/2026 6:30:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 5h 45m
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ALSA6h 15m010:30 AMSantanderBus Station4:45 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Bus Station, Santander (Spain) at 6/4/2026 10:30:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 6/4/2026 4:45:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 6h 15m
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FlixBus18h 30m06:50 PMSantanderBus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Santander (Spain) at 6/4/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 6/5/2026 1:20:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 18h 30m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Santander to Madrid
What are the most popular stations in Santander and Madrid?
In Santander, you will usually depart from Bus Station, Parayas Avenue Bus Stop or Astillero, while in Madrid you will be arriving at Atocha Train Station, Chamartin Train Station or Sur Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Madrid from Santander? With 9 connections between 3 Flight, Carpool and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Santander and Madrid, you can pay as low as $22 with a Flight from Air Nostrum.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Iberia: you will get to Madrid in just 1h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Santander and Madrid are ALSA, Iberia and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Santander and Madrid is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Santander Airport or to Delicias, and look at flights from Santander Airport, and landing at Adolfo Suárez Madrid-Barajas Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Santander to Madrid?
The most popular companies between Santander and Madrid, are ALSA, Iberia and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA and FlixBus
Airlines: Iberia and Air Nostrum
All you need to know when you travel from Santander to Madrid
Check all information on comfort and services on all modes of transports from Santander to Madrid. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Santander to Madrid
How can I reach Madrid from Santander?
Every day, there are on average 9 connections between Flight, Carpool and Bus, with which you can get to Madrid from Santander.
How far is Madrid from Santander?
The distance between Santander and Madrid is 210.6 miles.
What is the most ecofriendly mode of transport between Santander and Madrid?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 9 kgs of CO2, a train 12 kgs, a car 58 kgs, and a flight 83 kgs.
What is the cheapest mode of transport from Santander to Madrid?
You can get to Madrid with just $22 by taking a Flight from Air Nostrum.
What is the fastest way to get from Santander to Madrid?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Madrid in just 1h 10m with a Flight from Iberia.
More routes to Santander and to Madrid
Looking for more options? Here you can see the most popular routes to Santander and to Madrid. Simply click on a connection, and you’ll find all the details about the route!
