What is the best way to travel from Southampton to Manchester?
Looking for a trip? Compare all the available Flights, Trains and Buses for the journey to Manchester from Southampton. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Manchester from Southampton?
You can get to Manchester with just $33 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/29/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/29/2026 11:50:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 7h 45m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/29/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/29/2026 11:50:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m06:05 AMSouthamptonBus Station1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/29/2026 6:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/29/2026 1:50:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 7h 45m
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FlixBus7h 25m06:25 AMSouthamptonUniversity1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/29/2026 6:25:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/29/2026 1:50:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 7h 25m
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Eastern Air Lines (2011)4h 20m012:25 PMSouthampton AirportSouthampton Airport4:45 PMManchester AirportAirport Bus Station0EconomyA Flight from Eastern Air Lines (2011) goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/29/2026 12:25:00 PM to Airport Bus Station, Manchester Airport (United Kingdom) arriving at 10/29/2026 4:45:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 4h 20m
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KLM Cityhopper14h 45m05:35 PMSouthampton AirportSouthampton Airport8:20 AMManchester AirportAirport Bus Station0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/29/2026 5:35:00 PM to Airport Bus Station, Manchester Airport (United Kingdom) arriving at 10/30/2026 8:20:00 AM. 50 Economy ticket for $234 per person are available. Travel duration is 14h 45m
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KLM Cityhopper23h 40m08:40 AMSouthampton AirportSouthampton Airport8:20 AMManchester AirportAirport Bus Station0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/29/2026 8:40:00 AM to Airport Bus Station, Manchester Airport (United Kingdom) arriving at 10/30/2026 8:20:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 23h 40m
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Aer Lingus12h 30m07:40 PMSouthampton AirportSouthampton Airport8:10 AMManchester AirportAirport Bus Station0EconomyA Flight from Aer Lingus goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/29/2026 7:40:00 PM to Airport Bus Station, Manchester Airport (United Kingdom) arriving at 10/30/2026 8:10:00 AM. 50 Economy ticket for $307 per person are available. Travel duration is 12h 30m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/30/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/30/2026 11:50:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 7h 45m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/30/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/30/2026 11:50:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m06:05 AMSouthamptonBus Station1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/30/2026 6:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/30/2026 1:50:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 45m
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FlixBus10h 45m04:45 PMSouthamptonBus Station3:30 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/30/2026 4:45:00 PM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 3:30:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 10h 45m
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EasyJet Airline6h 55m02:45 PMSouthampton AirportSouthampton Airport9:40 PMLiverpool AirportLiverpool Airport0EconomyA Flight from EasyJet Airline goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/30/2026 2:45:00 PM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 10/30/2026 9:40:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 6h 55m
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EasyJet Airline6h 35m02:45 PMSouthampton AirportSouthampton Airport9:20 PMLiverpool AirportLiverpool Airport0EconomyA Flight from EasyJet Airline goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/30/2026 2:45:00 PM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 10/30/2026 9:20:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 6h 35m
Cheapest Buses Friday
Cheapest Flights Friday
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/31/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 11:50:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/31/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 11:50:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 7h 45m
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FlixBus7h 25m06:25 AMSouthamptonUniversity1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/31/2026 6:25:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 1:50:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 7h 25m
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FlixBus7h 45m06:05 AMSouthamptonBus Station1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/31/2026 6:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 1:50:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 7h 45m
Cheapest Buses Saturday
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/1/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/1/2026 11:50:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 7h 30m
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FlixBus7h 25m06:25 AMSouthamptonUniversity1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/1/2026 6:25:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/1/2026 1:50:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 7h 25m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/1/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/1/2026 11:50:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 7h 45m
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FlixBus7h 45m06:05 AMSouthamptonBus Station1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/1/2026 6:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/1/2026 1:50:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 7h 45m
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EasyJet Airline15h 55m07:30 PMSouthampton AirportSouthampton Airport11:25 AMLiverpool AirportLiverpool Airport0EconomyA Flight from EasyJet Airline goes from Southampton Airport, Southampton Airport (United Kingdom) at 11/1/2026 7:30:00 PM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 11/2/2026 11:25:00 AM. 50 Economy ticket for $234 per person are available. Travel duration is 15h 55m
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Loganair3h 55m09:20 AMSouthampton AirportSouthampton Airport1:15 PMLiverpool AirportLiverpool Airport0EconomyA Flight from Loganair goes from Southampton Airport, Southampton Airport (United Kingdom) at 11/1/2026 9:20:00 AM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 11/1/2026 1:15:00 PM. 50 Economy ticket for $238 per person are available. Travel duration is 3h 55m
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Eastern Air Lines (2011)6h 5m09:20 AMSouthampton AirportSouthampton Airport3:25 PMLiverpool AirportLiverpool Airport0EconomyA Flight from Eastern Air Lines (2011) goes from Southampton Airport, Southampton Airport (United Kingdom) at 11/1/2026 9:20:00 AM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 11/1/2026 3:25:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 6h 5m
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Eastern Air Lines (2011)7h 45m012:25 PMSouthampton AirportSouthampton Airport8:10 PMLiverpool AirportLiverpool Airport0EconomyA Flight from Eastern Air Lines (2011) goes from Southampton Airport, Southampton Airport (United Kingdom) at 11/1/2026 12:25:00 PM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 11/1/2026 8:10:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 7h 45m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus10h 45m04:45 PMSouthamptonBus Station3:30 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/2/2026 4:45:00 PM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 3:30:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 45m
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FlixBus10h 25m05:05 PMSouthamptonUniversity3:30 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/2/2026 5:05:00 PM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 3:30:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 25m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/2/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/2/2026 11:50:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 7h 45m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/2/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/2/2026 11:50:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 7h 30m
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South Western Railway5h 42m05:47 AMSouthamptonSwanwick Train Station11:29 AMManchesterPiccadilly Train Station0EconomyA Train from South Western Railway goes from Swanwick Train Station, Southampton (United Kingdom) at 11/2/2026 5:47:00 AM to Piccadilly Train Station, Manchester (United Kingdom) arriving at 11/2/2026 11:29:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 5h 42m
Cheapest Buses Monday
Cheapest Trains Monday
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/3/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 11:50:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/3/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 11:50:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 45m
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FlixBus8h 45m010:45 AMSouthamptonBus Station7:30 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/3/2026 10:45:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 7:30:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 45m
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FlixBus10h 45m04:45 PMSouthamptonBus Station3:30 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/3/2026 4:45:00 PM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/4/2026 3:30:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 10h 45m
Cheapest Buses Tuesday
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/4/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/4/2026 11:50:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 45m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/4/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/4/2026 11:50:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 7h 30m
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FlixBus10h 45m04:45 PMSouthamptonBus Station3:30 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/4/2026 4:45:00 PM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/5/2026 3:30:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 45m
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FlixBus10h 25m05:05 PMSouthamptonUniversity3:30 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/4/2026 5:05:00 PM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/5/2026 3:30:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 25m
Cheapest Buses Wednesday
What are the fastest trips from Southampton to Manchester?
You can get to Manchester from Southampton in just 3h 55m with a Flight from Loganair. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Eastern Air Lines (2011)4h 20m012:25 PMSouthampton AirportSouthampton Airport4:45 PMManchester AirportAirport Bus Station0EconomyA Flight from Eastern Air Lines (2011) goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/29/2026 12:25:00 PM to Airport Bus Station, Manchester Airport (United Kingdom) arriving at 10/29/2026 4:45:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 4h 20m
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Aer Lingus12h 30m07:40 PMSouthampton AirportSouthampton Airport8:10 AMManchester AirportAirport Bus Station0EconomyA Flight from Aer Lingus goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/29/2026 7:40:00 PM to Airport Bus Station, Manchester Airport (United Kingdom) arriving at 10/30/2026 8:10:00 AM. 50 Economy ticket for $307 per person are available. Travel duration is 12h 30m
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KLM Cityhopper14h 45m05:35 PMSouthampton AirportSouthampton Airport8:20 AMManchester AirportAirport Bus Station0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/29/2026 5:35:00 PM to Airport Bus Station, Manchester Airport (United Kingdom) arriving at 10/30/2026 8:20:00 AM. 50 Economy ticket for $234 per person are available. Travel duration is 14h 45m
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Aurigny Air Services22h 20m07:55 PMSouthampton AirportSouthampton Airport6:15 PMManchester AirportAirport Bus Station0EconomyA Flight from Aurigny Air Services goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/29/2026 7:55:00 PM to Airport Bus Station, Manchester Airport (United Kingdom) arriving at 10/30/2026 6:15:00 PM. 50 Economy ticket for $327 per person are available. Travel duration is 22h 20m
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FlixBus7h 25m06:25 AMSouthamptonUniversity1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/29/2026 6:25:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/29/2026 1:50:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 7h 25m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/29/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/29/2026 11:50:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/29/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/29/2026 11:50:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 7h 45m
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FlixBus7h 45m06:05 AMSouthamptonBus Station1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/29/2026 6:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/29/2026 1:50:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 7h 45m
Fastest Flights Thursday
Fastest Buses Thursday
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EasyJet Airline6h 35m02:45 PMSouthampton AirportSouthampton Airport9:20 PMLiverpool AirportLiverpool Airport0EconomyA Flight from EasyJet Airline goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/30/2026 2:45:00 PM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 10/30/2026 9:20:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 6h 35m
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EasyJet Airline6h 55m02:45 PMSouthampton AirportSouthampton Airport9:40 PMLiverpool AirportLiverpool Airport0EconomyA Flight from EasyJet Airline goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/30/2026 2:45:00 PM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 10/30/2026 9:40:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 6h 55m
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FlixBus7h 25m06:25 AMSouthamptonUniversity1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/30/2026 6:25:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/30/2026 1:50:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 25m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/30/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/30/2026 11:50:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/30/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/30/2026 11:50:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 7h 45m
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FlixBus7h 45m06:05 AMSouthamptonBus Station1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/30/2026 6:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/30/2026 1:50:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 45m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus7h 25m06:25 AMSouthamptonUniversity1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/31/2026 6:25:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 1:50:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 7h 25m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/31/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 11:50:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/31/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 11:50:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 7h 45m
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FlixBus7h 45m06:05 AMSouthamptonBus Station1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/31/2026 6:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 10/31/2026 1:50:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 7h 45m
Fastest Buses Saturday
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Loganair3h 55m09:20 AMSouthampton AirportSouthampton Airport1:15 PMLiverpool AirportLiverpool Airport0EconomyA Flight from Loganair goes from Southampton Airport, Southampton Airport (United Kingdom) at 11/1/2026 9:20:00 AM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 11/1/2026 1:15:00 PM. 50 Economy ticket for $238 per person are available. Travel duration is 3h 55m
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Eastern Air Lines (2011)6h 5m09:20 AMSouthampton AirportSouthampton Airport3:25 PMLiverpool AirportLiverpool Airport0EconomyA Flight from Eastern Air Lines (2011) goes from Southampton Airport, Southampton Airport (United Kingdom) at 11/1/2026 9:20:00 AM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 11/1/2026 3:25:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 6h 5m
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Eastern Air Lines (2011)7h 45m012:25 PMSouthampton AirportSouthampton Airport8:10 PMLiverpool AirportLiverpool Airport0EconomyA Flight from Eastern Air Lines (2011) goes from Southampton Airport, Southampton Airport (United Kingdom) at 11/1/2026 12:25:00 PM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 11/1/2026 8:10:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 7h 45m
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EasyJet Airline15h 55m07:30 PMSouthampton AirportSouthampton Airport11:25 AMLiverpool AirportLiverpool Airport0EconomyA Flight from EasyJet Airline goes from Southampton Airport, Southampton Airport (United Kingdom) at 11/1/2026 7:30:00 PM to Liverpool Airport, Liverpool Airport (United Kingdom) arriving at 11/2/2026 11:25:00 AM. 50 Economy ticket for $234 per person are available. Travel duration is 15h 55m
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FlixBus7h 25m06:25 AMSouthamptonUniversity1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/1/2026 6:25:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/1/2026 1:50:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 7h 25m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/1/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/1/2026 11:50:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/1/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/1/2026 11:50:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 7h 45m
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FlixBus7h 45m06:05 AMSouthamptonBus Station1:50 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/1/2026 6:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/1/2026 1:50:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 7h 45m
Fastest Flights Sunday
Fastest Buses Sunday
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South Western Railway5h 42m05:47 AMSouthamptonSwanwick Train Station11:29 AMManchesterPiccadilly Train Station0EconomyA Train from South Western Railway goes from Swanwick Train Station, Southampton (United Kingdom) at 11/2/2026 5:47:00 AM to Piccadilly Train Station, Manchester (United Kingdom) arriving at 11/2/2026 11:29:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 5h 42m
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/2/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/2/2026 11:50:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/2/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/2/2026 11:50:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 7h 45m
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FlixBus8h 45m010:45 AMSouthamptonBus Station7:30 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/2/2026 10:45:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/2/2026 7:30:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 8h 45m
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FlixBus10h 25m05:05 PMSouthamptonUniversity3:30 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/2/2026 5:05:00 PM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 3:30:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 25m
Fastest Trains Monday
Fastest Buses Monday
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/3/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 11:50:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/3/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 11:50:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 45m
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FlixBus8h 25m011:05 AMSouthamptonUniversity7:30 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/3/2026 11:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 7:30:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 25m
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FlixBus8h 45m010:45 AMSouthamptonBus Station7:30 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/3/2026 10:45:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/3/2026 7:30:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 45m
Fastest Buses Tuesday
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FlixBus7h 30m04:20 AMSouthamptonUniversity11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/4/2026 4:20:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/4/2026 11:50:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 7h 30m
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FlixBus7h 45m04:05 AMSouthamptonBus Station11:50 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/4/2026 4:05:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/4/2026 11:50:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 45m
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FlixBus8h 45m010:45 AMSouthamptonBus Station7:30 PMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 11/4/2026 10:45:00 AM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/4/2026 7:30:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 45m
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FlixBus10h 25m05:05 PMSouthamptonUniversity3:30 AMManchesterShudehill Interchange0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 11/4/2026 5:05:00 PM to Shudehill Interchange, Manchester (United Kingdom) arriving at 11/5/2026 3:30:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 25m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Southampton to Manchester
What are the most popular stations in Southampton and Manchester?
In Southampton, you will usually depart from Bus Station, Central Station or SeaCity Museum, while in Manchester you will be arriving at Shudehill Interchange, Piccadilly Train Station or Coach Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Manchester from Southampton? With 6 connections between 2 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Southampton and Manchester, you can pay as low as $33 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Loganair: you will get to Manchester in just 3h 55m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Southampton and Manchester are FlixBus, EasyJet Airline and Eastern Air Lines (2011), but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Southampton and Manchester is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Netley or to Salford, and look at flights from Bournemouth Airport, and landing at Liverpool Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Southampton to Manchester?
The most popular companies between Southampton and Manchester, are FlixBus, EasyJet Airline and Eastern Air Lines (2011). Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Train companies: South Western Railway
Airlines: EasyJet Airline, Eastern Air Lines (2011), KLM Cityhopper and 3 more.
All you need to know when you travel from Southampton to Manchester
Check all information on comfort and services on all modes of transports from Southampton to Manchester. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Southampton to Manchester
How can I reach Manchester from Southampton?
Every day, there are on average 6 connections between Flight, Train and Bus, with which you can get to Manchester from Southampton.
How far is Manchester from Southampton?
The distance between Southampton and Manchester is 181.2 miles.
What is the most ecofriendly mode of transport between Southampton and Manchester?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Southampton to Manchester?
You can get to Manchester with just $33 by taking a Bus from FlixBus.
What is the fastest way to get from Southampton to Manchester?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Manchester in just 3h 55m with a Flight from Loganair.
More routes to Southampton and to Manchester
Looking for more options? Here you can see the most popular routes to Southampton and to Manchester. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Southampton
- Barnsley to Southampton
- Birmingham to Southampton
- Bournemouth to Southampton
- Bradford to Southampton
- Brighton to Southampton
- Bristol to Southampton
- Edinburgh to Southampton
- Glasgow to Southampton
- Leeds to Southampton
- London Gatwick Airport to Southampton
- London to Southampton
- Manchester to Southampton
- Middlesbrough to Southampton
- Newcastle upon Tyne to Southampton
- Nottingham to Southampton
- Oxford to Southampton
- Plymouth to Southampton
- Ringwood to Southampton
- Sheffield to Southampton
- Trips to Manchester
- Amsterdam to Manchester
- Bath to Manchester
- Birmingham to Manchester
- Blackpool to Manchester
- Bournemouth to Manchester
- Bristol to Manchester
- Brussels to Manchester
- Cambridge to Manchester
- Dorchester to Manchester
- Dundee to Manchester
- Edinburgh to Manchester
- Glasgow to Manchester
- Inverness to Manchester
- Leeds to Manchester
- London Heathrow Airport to Manchester
- London Stansted Airport to Manchester
- London to Manchester
- Luton to Manchester
- Newcastle upon Tyne to Manchester
- Oxford to Manchester
- Plymouth to Manchester
- Portsmouth to Manchester
- Prague to Manchester
- Preston to Manchester
