Bus from Southampton to Manchester from $24

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Compare all timetables for the bus from Southampton to Manchester

Here is a selection of the cheapest bus trips from the schedule from Southampton to Manchester from various bus operators like FlixBus for the next days.
today
from $38
tomorrow
from $55
Sunday
Monday
from $30
Tuesday
from $27
Wednesday
from $24
Thursday
from $39

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    5:00 PM
    Southampton
    Bus Station
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $38
  • FlixBus
    12h 50m
    0
    5:00 PM
    Southampton
    Bus Station
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    12h 55m
    0
    5:15 PM
    Southampton
    Burgess Road
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $38
  • FlixBus
    12h 35m
    0
    5:15 PM
    Southampton
    Burgess Road
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $38
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $15? You can find the corresponding connections below.
    • National Express
      5h 40m
      0
      4:00 PM
      Southampton
      Bus Station
      7:25 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $14
      • Waiting Time 0h 5m
    • National Express
      2h 10m
      0
      7:30 PM
      Birmingham
      Coach Station
      9:40 PM
      Manchester
      Coach Station
      0
      National Express
      Economy
      $9
    Travel Time is 6h 55m shorter, and you will save $15

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    5:00 PM
    Southampton
    Bus Station
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $55
  • FlixBus
    12h 50m
    0
    5:00 PM
    Southampton
    Bus Station
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $55
  • FlixBus
    12h 55m
    0
    5:15 PM
    Southampton
    Burgess Road
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $55
  • FlixBus
    12h 35m
    0
    5:15 PM
    Southampton
    Burgess Road
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $55
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $32? You can find the corresponding connections below.
    • National Express
      5h 40m
      0
      4:00 PM
      Southampton
      Bus Station
      7:25 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $14
      • Waiting Time 0h 5m
    • National Express
      2h 10m
      0
      7:30 PM
      Birmingham
      Coach Station
      9:40 PM
      Manchester
      Coach Station
      0
      National Express
      Economy
      $9
    Travel Time is 6h 55m shorter, and you will save $32

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    5:00 PM
    Southampton
    Bus Station
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $30
  • FlixBus
    12h 50m
    0
    5:00 PM
    Southampton
    Bus Station
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $30
  • FlixBus
    12h 55m
    0
    5:15 PM
    Southampton
    Burgess Road
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $30
  • FlixBus
    12h 35m
    0
    5:15 PM
    Southampton
    Burgess Road
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $30
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $9? You can find the corresponding connections below.
    • National Express
      7h 45m
      0
      8:55 AM
      Southampton
      Bus Station
      12:30 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $14
      • Waiting Time 1h 40m
    • FlixBus
      2h 30m
      0
      2:10 PM
      Birmingham
      Great Charles St Queensway
      4:40 PM
      Manchester
      Shudehill Interchange
      0
      FlixBus
      Economy
      $7
    Travel Time is 4h 50m shorter, and you will save $9

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    5:00 PM
    Southampton
    Bus Station
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $27
  • FlixBus
    12h 50m
    0
    5:00 PM
    Southampton
    Bus Station
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $27
  • FlixBus
    12h 55m
    0
    5:15 PM
    Southampton
    Burgess Road
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $27
  • FlixBus
    12h 35m
    0
    5:15 PM
    Southampton
    Burgess Road
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $27
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $6? You can find the corresponding connections below.
    • National Express
      7h 45m
      0
      8:55 AM
      Southampton
      Bus Station
      12:30 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $14
      • Waiting Time 1h 40m
    • FlixBus
      2h 30m
      0
      2:10 PM
      Birmingham
      Great Charles St Queensway
      4:40 PM
      Manchester
      Shudehill Interchange
      0
      FlixBus
      Economy
      $7
    Travel Time is 4h 50m shorter, and you will save $6

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    5:00 PM
    Southampton
    Bus Station
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $24
  • FlixBus
    12h 50m
    0
    5:00 PM
    Southampton
    Bus Station
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $24
  • FlixBus
    12h 35m
    0
    5:15 PM
    Southampton
    Burgess Road
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $24
  • FlixBus
    12h 55m
    0
    5:15 PM
    Southampton
    Burgess Road
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $24
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $3? You can find the corresponding connections below.
    • National Express
      7h 45m
      0
      8:55 AM
      Southampton
      Bus Station
      12:30 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $14
      • Waiting Time 1h 40m
    • FlixBus
      2h 30m
      0
      2:10 PM
      Birmingham
      Great Charles St Queensway
      4:40 PM
      Manchester
      Shudehill Interchange
      0
      FlixBus
      Economy
      $7
    Travel Time is 4h 50m shorter, and you will save $3

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    13h 10m
    0
    5:00 PM
    Southampton
    Bus Station
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $39
  • FlixBus
    12h 50m
    0
    5:00 PM
    Southampton
    Bus Station
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $39
  • FlixBus
    12h 55m
    0
    5:15 PM
    Southampton
    Burgess Road
    6:10 AM
    Manchester
    Shudehill Interchange
    0
    FlixBus
    Economy
    $39
  • FlixBus
    12h 35m
    0
    5:15 PM
    Southampton
    Burgess Road
    5:50 AM
    Manchester
    Moss Lane East Station
    0
    FlixBus
    Economy
    $39
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $18? You can find the corresponding connections below.
    • National Express
      7h 45m
      0
      8:55 AM
      Southampton
      Bus Station
      12:30 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $14
      • Waiting Time 1h 40m
    • FlixBus
      2h 30m
      0
      2:10 PM
      Birmingham
      Great Charles St Queensway
      4:40 PM
      Manchester
      Shudehill Interchange
      0
      FlixBus
      Economy
      $7
    Travel Time is 4h 50m shorter, and you will save $18

Facts about the bus from Southampton to Manchester

Compare all providers like FlixBus that travel 4 times every day by bus from Southampton to Manchester in one click! Book your bus ticket from Southampton to Manchester starting from $24!

Cheapest Bus $24
Fastest Bus 12h 35m
Earliest Bus 5:00 PM
Latest Bus 5:15 PM
Daily Bus Routes 4 Ø
Distance 181.2 miles
Bus Companies FlixBus

Cheapest bus connections from Southampton to Manchester

Every day, 4 buses from 1 bus companies leave Southampton for Manchester: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
Thursday 06/19
Friday 06/20
$38
Saturday 06/21
$55
Sunday 06/22
$116
Monday 06/23
$30
Tuesday 06/24
$27
Wednesday 06/25
$24
Thursday 06/26
$39
Friday 06/27
$27
Saturday 06/28
$35
Sunday 06/29
Monday 06/30
$23
Tuesday 07/01
$29
Wednesday 07/02
Thursday 07/03
$31
Friday 07/04
Saturday 07/05
$17
Sunday 07/06
$35
Monday 07/07
Tuesday 07/08
Wednesday 07/09
$33
Thursday 07/10
$33
Friday 07/11
Saturday 07/12

How to save money travelling from Southampton to Manchester

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Southampton to Manchester in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Southampton to Manchester, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Southampton to Manchester are also emptier.

Beloved bus companies from Southampton to Manchester

These are the most booked bus companies between Southampton to Manchester from our users.

FlixBus from Southampton to Manchester

FlixBus

Here you will find the key facts about the FlixBus bus route Southampton to Manchester:

Cheapest Price $24
Fastest Bus 12h 35m
Earliest Bus 5:00 PM
Last Bus 5:15 PM
Daily Connections 4 Ø
Found on 6/18/2025

All bus stations and stops in Southampton and Manchester

In the map below, you can see where to find all bus stations in Southampton and Manchester.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Southampton to Manchester? Compare all modes of transports from Southampton to Manchester.

Service and Comfort on the bus from Southampton to Manchester

Want to know which seat classes are available on the buses from Southampton to Manchester? Or which bus companies serve the route Southampton to Manchester? Below you will find answers to your questions.

FAQs about the Southampton to Manchester bus

How much does a Southampton Manchester bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $24 and takes 13h 10m to reach Manchester. Compare offers to save money!

How much could I save by comparing buses from Southampton to Manchester?

This route is offered by 1 companies with a range of ticket prices between $24 and $55. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Manchester.

On average, how many connections are available from Southampton to Manchester each day?

Every day, the Southampton to Manchester bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Southampton to Manchester take?

The fastest bus from Southampton to Manchester is offered by FlixBus and takes 12h 35m. Bus tickets for this connection cost $38. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Southampton to Manchester?

The earliest bus arriving in Manchester from Southampton starts at 5:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Southampton to Manchester?

The latest bus trip departing from Southampton for Manchester starts at 5:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Southampton Manchester route?

When traveling by bus from Southampton to Manchester, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Southampton and Manchester?

You can check all the direct connections between Southampton and Manchester by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Southampton to Manchester bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Southampton Manchester bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Southampton Manchester bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Southampton to Manchester on your planned travel date.

Available seat classes which are offered on the bus route Southampton to Manchester

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Southampton and to Manchester

Here’s an overview of the most popular bus routes to Southampton and to Manchester. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to Southampton from Portsmouth Buses to Southampton from Portsmouth
Bus Cardiff - Southampton Bus Cardiff - Southampton
Bus Brighton to Southampton Bus Brighton to Southampton
Bus from Leicester to Southampton Bus from Leicester to Southampton
Bus from Windermere to Manchester Bus from Windermere to Manchester
Bus from Cardiff to Manchester Bus from Cardiff to Manchester
Buses Oxford to Manchester Buses Oxford to Manchester
Bus from Cambridge to Manchester Bus from Cambridge to Manchester
Popular Airport Shuttles to Southampton and to Manchester
CheckMyBus › Buses in United Kingdom › Bus to Southampton › Bus to Manchester

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