Bus from Southampton to Manchester from $42

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Compare all timetables for the bus from Southampton to Manchester

Here is a selection of the cheapest bus trips from the schedule from Southampton to Manchester from various bus operators like FlixBus for the next days.

today
$42
tomorrow
Friday
$49
Saturday
$48
Sunday
$53
Monday
Tuesday
$46

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 10m 5:00 PM Southampton Bus Station 6:10 AM Manchester Shudehill Interchange  Economy $42
FlixBus 12h 50m 5:00 PM Southampton Bus Station 5:50 AM Manchester Moss Lane East Station  Economy $42
FlixBus 12h 35m 5:15 PM Southampton University 5:50 AM Manchester Moss Lane East Station  Economy $42
FlixBus 12h 55m 5:15 PM Southampton University 6:10 AM Manchester Shudehill Interchange  Economy $42
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $17? You can find the corresponding connections below.
    • National Express
      12h 55m
      0
      2:20 AM
      Southampton
      University
      9:10 AM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $16
      • Waiting Time 3h 40m
    • National Express
      2h 25m
      0
      12:50 PM
      Birmingham
      Coach Station
      3:15 PM
      Manchester
      Coach Station
      0
      National Express
      Economy
      $8
    Travel time is 0h 20m longer, but you will save $17

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 8h 35m 10:45 AM Southampton Bus Station 7:20 PM Manchester Shudehill Interchange  Economy $49
FlixBus 8h 20m 11:00 AM Southampton University 7:20 PM Manchester Shudehill Interchange  Economy $49
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $23? You can find the corresponding connections below.
    • National Express
      9h 55m
      0
      2:20 AM
      Southampton
      University
      9:10 AM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $16
      • Waiting Time 0h 50m
    • National Express
      2h 15m
      0
      10:00 AM
      Birmingham
      Coach Station
      12:15 PM
      Manchester
      Coach Station
      0
      National Express
      Economy
      $9
    Travel time is 1h 35m longer, but you will save $23

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 8h 35m 10:45 AM Southampton Bus Station 7:20 PM Manchester Shudehill Interchange  Economy $48
FlixBus 8h 20m 11:00 AM Southampton University 7:20 PM Manchester Shudehill Interchange  Economy $48
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $24? You can find the corresponding connections below.
    • National Express
      6h 30m
      0
      12:10 PM
      Southampton
      Bus Station
      4:00 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $16
      • Waiting Time 0h 10m
    • FlixBus
      2h 30m
      0
      4:10 PM
      Birmingham
      Great Charles St Queensway
      6:40 PM
      Manchester
      Shudehill Interchange
      0
      FlixBus
      Economy
      $8
    Travel Time is 1h 50m shorter, and you will save $24

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 8h 35m 10:45 AM Southampton Bus Station 7:20 PM Manchester Shudehill Interchange  Economy $53
FlixBus 8h 20m 11:00 AM Southampton University 7:20 PM Manchester Shudehill Interchange  Economy $53
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $34? You can find the corresponding connections below.
    • National Express
      6h 30m
      0
      12:10 PM
      Southampton
      Bus Station
      4:00 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $11
      • Waiting Time 0h 10m
    • FlixBus
      2h 30m
      0
      4:10 PM
      Birmingham
      Great Charles St Queensway
      6:40 PM
      Manchester
      Shudehill Interchange
      0
      FlixBus
      Economy
      $8
    Travel Time is 1h 50m shorter, and you will save $34

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 8h 35m 10:45 AM Southampton Bus Station 7:20 PM Manchester Shudehill Interchange  Economy $46
FlixBus 8h 20m 11:00 AM Southampton University 7:20 PM Manchester Shudehill Interchange  Economy $46
  • Did you know that if you travel from Southampton to Manchester via Birmingham, you can save more than $27? You can find the corresponding connections below.
    • National Express
      5h 40m
      0
      4:00 PM
      Southampton
      Bus Station
      7:25 PM
      Birmingham
      Coach Station
      0
      National Express
      Economy
      $11
      • Waiting Time 0h 5m
    • National Express
      2h 10m
      0
      7:30 PM
      Birmingham
      Coach Station
      9:40 PM
      Manchester
      Coach Station
      0
      National Express
      Economy
      $8
    Travel Time is 2h 40m shorter, and you will save $27

Best Price Offer: The price for the cheapest bus from Southampton to Manchester is $42 on 2/4/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Southampton and Manchester

See here how frequent the connections between Southampton and Manchester are, during different times and days of the week.
Wednesday is the busiest day, with more than 4 daily buses from Southampton to Manchester. Sunday has instead the fewest connections, with only 2 daily coaches between Southampton and Manchester.
The busiest time of the day is the Morning, with 8 buses from Southampton to Manchester, while Afternoon sees the fewest connections between Southampton and Manchester, with 4 offers.

Facts about the bus from Southampton to Manchester

Compare all providers like FlixBus that travel 2 times every day by bus from Southampton to Manchester in one click! Book your bus ticket from Southampton to Manchester starting from $42!

Cheapest Bus $42
Fastest Bus 8h 20m
Earliest Bus 5:00 PM
Latest Bus 11:00 AM
Daily Bus Routes 2 Ø
Distance 181.2 miles
Bus Companies FlixBus

Cheapest bus connections from Southampton to Manchester

Every day, 2 buses from 1 bus companies leave Southampton for Manchester: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/04/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
$42
Thursday 02/05
Friday 02/06
$49
Saturday 02/07
$48
Sunday 02/08
$53
Monday 02/09
Tuesday 02/10
$46
Wednesday 02/11
$47
Thursday 02/12
Friday 02/13
$58
Saturday 02/14
Sunday 02/15
$58
Monday 02/16
Tuesday 02/17
$52
Wednesday 02/18
Thursday 02/19
Friday 02/20
$56
Saturday 02/21
Sunday 02/22
$58
Monday 02/23
$53
Tuesday 02/24
Wednesday 02/25
$47
Thursday 02/26
$46
Friday 02/27
$49
Saturday 02/28

The cheapest time to travel from Southampton to Manchester

See here on which day and which time of the day you can find the cheapest bus ticket from Southampton to Manchester, for the next 30 days.
With a price starting from $42, Wednesday is the cheapest day for a bus from Southampton to Manchester. Sunday instead is the most expensive day with prices starting from $50.
Afternoon is the cheapest day time for bus tickets from Southampton to Manchester, with $42. Morning is the most expensive time of the day with prices starting from $46.

How to save money travelling from Southampton to Manchester

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Southampton to Manchester in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Southampton to Manchester, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Southampton to Manchester are also emptier.

All bus stations and stops in Southampton and Manchester

In the map below, you can see where to find all bus stations in Southampton and Manchester.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Southampton to Manchester? Compare all modes of transports from Southampton to Manchester.

Service and Comfort on the bus from Southampton to Manchester

Want to know which seat classes are available on the buses from Southampton to Manchester? Or which bus companies serve the route Southampton to Manchester? Below you will find answers to your questions.

FAQs about the Southampton to Manchester bus

How much does a Southampton Manchester bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 13h 10m to reach Manchester. Compare offers to save money!

How much could I save by comparing buses from Southampton to Manchester?

This route is offered by 1 companies with a range of ticket prices between $42 and $53. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Manchester.

On average, how many connections are available from Southampton to Manchester each day?

Every day, the Southampton to Manchester bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Southampton to Manchester take?

The fastest bus from Southampton to Manchester is offered by FlixBus and takes 8h 20m. Bus tickets for this connection cost $49. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Southampton to Manchester?

The earliest bus arriving in Manchester from Southampton starts at 5:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Southampton to Manchester?

The latest bus trip departing from Southampton for Manchester starts at 11:00 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Southampton Manchester route?

When traveling by bus from Southampton to Manchester, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Southampton and Manchester?

You can check all the direct connections between Southampton and Manchester by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Southampton to Manchester bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Southampton Manchester bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Southampton Manchester bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Southampton to Manchester on your planned travel date.

How does CheckMyBus find the best bus deals from Southampton to Manchester?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Southampton and Manchester. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Southampton to Manchester?

Prices and availability for 2 trips between Southampton and Manchester change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Southampton to Manchester

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Southampton and to Manchester

Here’s an overview of the most popular bus routes to Southampton and to Manchester. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Birchington to Southampton Bus Birchington to Southampton
Helston to Southampton bus Helston to Southampton bus
Buses to Southampton from West Drayton Buses to Southampton from West Drayton
Buses from Neath to Southampton Buses from Neath to Southampton
Watford to Manchester bus Watford to Manchester bus
Bus Eindhoven - Manchester Bus Eindhoven - Manchester
Bus Newport (Wales) - Manchester Bus Newport (Wales) - Manchester
Buses to Manchester from Milton Keynes Buses to Manchester from Milton Keynes
Popular Airport Shuttles to Southampton and to Manchester
CheckMyBus › Buses in United Kingdom › Bus to Southampton › Bus to Manchester

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