Compare all timetables for the bus from Middlesbrough to Southampton
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Express | 9h 20m | 4:10 PM | Middlesbrough | Bus Station | 1:30 AM | Southampton | Bus Station | Economy | $40 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/20/2026 4:10:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/21/2026 1:30:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 9h 20m
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| National Express | 11h 10m | 9:30 AM | Middlesbrough | Bus Station | 8:40 PM | Southampton | Bus Station | Economy | $41 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/20/2026 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/20/2026 8:40:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 11h 10m
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| National Express | 10h 40m | 1:25 PM | Middlesbrough | Bus Station | 12:05 AM | Southampton | Bus Station | Economy | $45 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/20/2026 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/21/2026 12:05:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 10h 40m
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| National Express | 10h 10m | 7:20 AM | Middlesbrough | Bus Station | 5:30 PM | Southampton | Bus Station | Economy | $51 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/20/2026 7:20:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/20/2026 5:30:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 10h 10m
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| National Express | 10h 5m | 10:45 AM | Middlesbrough | Bus Station | 8:50 PM | Southampton | Bus Station | Economy | $51 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/20/2026 10:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/20/2026 8:50:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 10h 5m
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National ExpressSave more than 2%10h 40mMiddlesbrough3 mi1:10 PMBillinghamBus Stop11:50 PMSouthamptonUniversity0 miEconomyA Bus from National Express goes from Bus Stop, Billingham (United Kingdom) at 4/20/2026 1:10:00 PM to University, Southampton (United Kingdom) arriving at 4/20/2026 11:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 10h 40m
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FlixBus12h 25m08:35 AMMiddlesbroughBus Station12:10 PMSheffieldMeadowhall Interchange0EconomyA Bus from FlixBus goes from Bus Station, Middlesbrough (United Kingdom) at 4/21/2026 8:35:00 AM to Meadowhall Interchange, Sheffield (United Kingdom) arriving at 4/21/2026 12:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 3h 35m
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National Express8h 15m012:45 PMSheffieldBus Station9:00 PMSouthamptonBus Station0EconomyA Bus from National Express goes from Bus Station, Sheffield (United Kingdom) at 4/21/2026 12:45:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/21/2026 9:00:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 8h 15m
Waiting Time 0h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Express | 10h 40m | 9:30 AM | Middlesbrough | Bus Station | 8:10 PM | Southampton | Bus Station | Economy | $23 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/21/2026 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/21/2026 8:10:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 10h 40m
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| National Express | 10h 10m | 1:25 PM | Middlesbrough | Bus Station | 11:35 PM | Southampton | Bus Station | Economy | $23 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/21/2026 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/21/2026 11:35:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 10h 10m
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| National Express | 10h 50m | 4:10 PM | Middlesbrough | Bus Station | 3:00 AM | Southampton | Bus Station | Economy | $23 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/21/2026 4:10:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/22/2026 3:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 10h 50m
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| National Express | 10h 30m | 7:00 AM | Middlesbrough | Bus Station | 5:30 PM | Southampton | Bus Station | Economy | $33 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/21/2026 7:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/21/2026 5:30:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 10h 30m
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| National Express | 10h 35m | 12:45 AM | Middlesbrough | Bus Station | 11:20 AM | Southampton | Bus Station | Economy | $37 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/21/2026 12:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/21/2026 11:20:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Express | 10h 50m | 4:10 PM | Middlesbrough | Bus Station | 3:00 AM | Southampton | Bus Station | Economy | $23 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/22/2026 4:10:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/23/2026 3:00:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 10h 50m
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| National Express | 10h 40m | 9:30 AM | Middlesbrough | Bus Station | 8:10 PM | Southampton | Bus Station | Economy | $24 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/22/2026 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/22/2026 8:10:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 10h 40m
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| National Express | 10h 10m | 1:25 PM | Middlesbrough | Bus Station | 11:35 PM | Southampton | Bus Station | Economy | $24 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/22/2026 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/22/2026 11:35:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 10h 10m
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| National Express | 10h 30m | 7:00 AM | Middlesbrough | Bus Station | 5:30 PM | Southampton | Bus Station | Economy | $33 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/22/2026 7:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/22/2026 5:30:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 10h 30m
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| National Express | 9h 50m | 11:00 AM | Middlesbrough | Bus Station | 8:50 PM | Southampton | Bus Station | Economy | $37 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/22/2026 11:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/22/2026 8:50:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 9h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Express | 10h 40m | 9:30 AM | Middlesbrough | Bus Station | 8:10 PM | Southampton | Bus Station | Economy | $23 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/23/2026 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/23/2026 8:10:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 10h 40m
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| National Express | 10h 10m | 1:25 PM | Middlesbrough | Bus Station | 11:35 PM | Southampton | Bus Station | Economy | $23 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/23/2026 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/23/2026 11:35:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 10h 10m
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| National Express | 10h 50m | 4:10 PM | Middlesbrough | Bus Station | 3:00 AM | Southampton | Bus Station | Economy | $24 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/23/2026 4:10:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/24/2026 3:00:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 10h 50m
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| National Express | 9h 50m | 11:00 AM | Middlesbrough | Bus Station | 8:50 PM | Southampton | Bus Station | Economy | $37 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/23/2026 11:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/23/2026 8:50:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 9h 50m
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| National Express | 10h 30m | 7:00 AM | Middlesbrough | Bus Station | 5:30 PM | Southampton | Bus Station | Economy | $39 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/23/2026 7:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/23/2026 5:30:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 10h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Express | 11h 10m | 9:30 AM | Middlesbrough | Bus Station | 8:40 PM | Southampton | Bus Station | Economy | $23 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/24/2026 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/24/2026 8:40:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 11h 10m
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| National Express | 10h 40m | 1:25 PM | Middlesbrough | Bus Station | 12:05 AM | Southampton | Bus Station | Economy | $23 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/24/2026 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/25/2026 12:05:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 10h 40m
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| National Express | 9h 20m | 4:10 PM | Middlesbrough | Bus Station | 1:30 AM | Southampton | Bus Station | Economy | $24 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/24/2026 4:10:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/25/2026 1:30:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 9h 20m
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| National Express | 10h 45m | 7:00 AM | Middlesbrough | Bus Station | 5:45 PM | Southampton | Bus Station | Economy | $36 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/24/2026 7:00:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/24/2026 5:45:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 45m
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| National Express | 10h 5m | 10:45 AM | Middlesbrough | Bus Station | 8:50 PM | Southampton | Bus Station | Economy | $37 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/24/2026 10:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/24/2026 8:50:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Express | 10h 20m | 9:30 AM | Middlesbrough | Bus Station | 7:50 PM | Southampton | Bus Station | Economy | $27 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/25/2026 9:30:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/25/2026 7:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 10h 20m
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| National Express | 9h 50m | 10:45 AM | Middlesbrough | Bus Station | 8:35 PM | Southampton | Bus Station | Economy | $27 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/25/2026 10:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/25/2026 8:35:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 9h 50m
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| National Express | 10h 40m | 1:25 PM | Middlesbrough | Bus Station | 12:05 AM | Southampton | Bus Station | Economy | $27 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/25/2026 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/26/2026 12:05:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 10h 40m
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| National Express | 9h 15m | 4:15 PM | Middlesbrough | Bus Station | 1:30 AM | Southampton | Bus Station | Economy | $27 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/25/2026 4:15:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/26/2026 1:30:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 9h 15m
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| National Express | 9h 40m | 7:35 AM | Middlesbrough | Bus Station | 5:15 PM | Southampton | Bus Station | Economy | $30 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/25/2026 7:35:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/25/2026 5:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Express | 10h 35m | 12:45 AM | Middlesbrough | Bus Station | 11:20 AM | Southampton | Bus Station | Economy | $41 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/26/2026 12:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/26/2026 11:20:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 10h 35m
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| National Express | 10h 40m | 1:25 PM | Middlesbrough | Bus Station | 12:05 AM | Southampton | Bus Station | Economy | $46 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/26/2026 1:25:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/27/2026 12:05:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 40m
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| National Express | 9h 15m | 4:15 PM | Middlesbrough | Bus Station | 1:30 AM | Southampton | Bus Station | Economy | $46 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/26/2026 4:15:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/27/2026 1:30:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 9h 15m
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| National Express | 9h 50m | 10:45 AM | Middlesbrough | Bus Station | 8:35 PM | Southampton | Bus Station | Economy | $55 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/26/2026 10:45:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/26/2026 8:35:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 9h 50m
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| National Express | 9h 40m | 7:35 AM | Middlesbrough | Bus Station | 5:15 PM | Southampton | Bus Station | Economy | $59 |
A Bus from National Express goes from Bus Station, Middlesbrough (United Kingdom) at 4/26/2026 7:35:00 AM to Bus Station, Southampton (United Kingdom) arriving at 4/26/2026 5:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 9h 40m
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National ExpressSave more than 34%10h 40mMiddlesbrough3 mi1:10 PMBillinghamBus Stop11:50 PMSouthamptonUniversity0 miEconomyA Bus from National Express goes from Bus Stop, Billingham (United Kingdom) at 4/26/2026 1:10:00 PM to University, Southampton (United Kingdom) arriving at 4/26/2026 11:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 10h 40m
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FlixBus12h 25m08:35 AMMiddlesbroughBus Station12:10 PMSheffieldMeadowhall Interchange0EconomyA Bus from FlixBus goes from Bus Station, Middlesbrough (United Kingdom) at 4/21/2026 8:35:00 AM to Meadowhall Interchange, Sheffield (United Kingdom) arriving at 4/21/2026 12:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 3h 35m
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National Express8h 15m012:45 PMSheffieldBus Station9:00 PMSouthamptonBus Station0EconomyA Bus from National Express goes from Bus Station, Sheffield (United Kingdom) at 4/21/2026 12:45:00 PM to Bus Station, Southampton (United Kingdom) arriving at 4/21/2026 9:00:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 8h 15m
Waiting Time 0h 35m -
Best Price Offer: The price for the cheapest bus from Middlesbrough to Southampton is $23 on 4/21/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Middlesbrough and Southampton
Facts about the bus from Middlesbrough to Southampton
Compare all providers like National Express that travel 6 times every day by bus from Middlesbrough to Southampton in one click! Book your bus ticket from Middlesbrough to Southampton starting from $23!
| Cheapest Bus | $23 |
| Fastest Bus | 9h 15m |
| Earliest Bus | 12:45 AM |
| Latest Bus | 4:15 PM |
| Daily Bus Routes | 6 Ø |
| Distance | 253.4 miles |
| Bus Companies | National Express |
Cheapest bus connections from Middlesbrough to Southampton
Every day, 6 buses from 1 bus companies leave Middlesbrough for Southampton: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.
The cheapest time to travel from Middlesbrough to Southampton
How to save money travelling from Middlesbrough to Southampton
Book the ticket from Middlesbrough to Southampton in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Middlesbrough to Southampton, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Middlesbrough to Southampton are also emptier.All bus stations and stops in Middlesbrough and Southampton
In the map below, you can see where to find all bus stations in Middlesbrough and Southampton.
Service and Comfort on the bus from Middlesbrough to Southampton
FAQs about the Middlesbrough to Southampton bus
How much does a Middlesbrough Southampton bus trip cost?
How much could I save by comparing buses from Middlesbrough to Southampton?
On average, how many connections are available from Middlesbrough to Southampton each day?
How long does a bus journey from Middlesbrough to Southampton take?
What time is the first bus from Middlesbrough to Southampton?
What time is the last bus from Middlesbrough to Southampton?
Which bus companies operate the Middlesbrough Southampton route?
Is there a direct bus between Middlesbrough and Southampton?
What can I take with me on the Middlesbrough to Southampton bus route?
What equipment is available for the Middlesbrough Southampton bus route?
How does CheckMyBus find the best bus deals from Middlesbrough to Southampton?
How does CheckMyBus technology work for trips from Middlesbrough to Southampton?
Available seat classes which are offered on the bus route Middlesbrough to Southampton
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Middlesbrough and to Southampton
- Bus Routes to Middlesbrough
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- Bridgwater to Middlesbrough bus
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- Bus from Durham to Middlesbrough
- Bus to Middlesbrough from Edinburgh
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- Bus from Leeds to Middlesbrough
- Bus Leicester - Middlesbrough
- Bus from Liverpool to Middlesbrough
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- Bus Routes to Southampton
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- Bus Bath to Southampton
- Bus from Birchington to Southampton
- Bus Birkenhead - Southampton
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- From Leicester to Southampton bus
- Bus London to Southampton
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- Buses to Southampton from Sheffield
- Bus from Weymouth to Southampton
