How to get from St. Louis, MO to Detroit

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What is the best way to travel from St. Louis, MO to Detroit?

Looking for a trip? Compare all the available Flights and Buses for the journey to Detroit from St. Louis, MO. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
13h 10m
$67
$78
8
Flight
4h 58m
$181
$248
43

What is the cheapest way to reach Detroit from St. Louis, MO?

You can get to Detroit with just $67 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Friday
from $85
Saturday
from $71
Sunday
from $79
Monday
Tuesday
from $67
Wednesday
from $69
Thursday
from $87

    Cheapest Buses Friday

  • FlixBus
    14h 15m
    0
    11:30 PM
    St. Louis, MO
    Gateway Station
    2:45 PM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $85
  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $88
  • FlixBus
    15h 20m
    0
    2:30 PM
    St. Louis, MO
    Gateway Station
    6:50 AM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $88
  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $89

    Cheapest Buses Saturday

  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $71
  • FlixBus
    14h 15m
    0
    11:30 PM
    St. Louis, MO
    Gateway Station
    2:45 PM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $71
  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $72
  • FlixBus
    15h 20m
    0
    2:30 PM
    St. Louis, MO
    Gateway Station
    6:50 AM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $72
  • Cheapest Flights Saturday

  • United Airlines
    6h 28m
    0
    6:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:28 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $210
  • United Airlines
    8h 23m
    0
    6:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    3:23 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $210
  • United Airlines
    4h 58m
    0
    7:30 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:28 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $210
  • Frontier Airlines
    26h 52m
    0
    7:59 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    11:51 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from $242
  • Frontier Airlines
    15h 26m
    0
    4:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    8:52 AM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from $261

    Cheapest Buses Sunday

  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $79
  • FlixBus
    14h 15m
    0
    11:30 PM
    St. Louis, MO
    Gateway Station
    2:45 PM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $79
  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $80
  • FlixBus
    15h 20m
    0
    2:30 PM
    St. Louis, MO
    Gateway Station
    6:50 AM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $80

    Cheapest Buses Tuesday

  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $67
  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $67
  • FlixBus
    15h 20m
    0
    2:30 PM
    St. Louis, MO
    Gateway Station
    6:50 AM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $67

    Cheapest Buses Wednesday

  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $69
  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $69
  • Greyhound US
    18h 50m
    0
    2:05 PM
    St. Louis, MO
    Gateway Station
    9:55 AM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $70

    Cheapest Buses Thursday

  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    18h 50m
    0
    2:05 PM
    St. Louis, MO
    Gateway Station
    9:55 AM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $87
  • FlixBus
    14h 15m
    0
    11:30 PM
    St. Louis, MO
    Gateway Station
    2:45 PM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $87
  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $88
  • Cheapest Flights Thursday

  • Frontier Airlines
    23h 37m
    0
    7:24 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    8:01 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from $181
  • United Airlines
    4h 58m
    0
    7:30 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:28 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $183
  • United Airlines
    6h 22m
    0
    1:08 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    8:30 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $183
  • Frontier Airlines
    16h 14m
    0
    7:24 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    12:38 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from $213
  • Alaska Airlines
    9h 47m
    0
    6:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    4:47 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Alaska Airlines
    Economy
    from $585

What are the fastest trips from St. Louis, MO to Detroit?

You can get to Detroit from St. Louis, MO in just 4h 58m with a Flight from United Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Friday
from 13h 10m
Saturday
from 4h 58m
Sunday
from 13h 10m
Monday
Tuesday
from 13h 10m
Wednesday
from 13h 10m
Thursday
from 4h 58m

    Fastest Buses Friday

  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $89
  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $88
  • FlixBus
    14h 15m
    0
    11:30 PM
    St. Louis, MO
    Gateway Station
    2:45 PM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $85
  • FlixBus
    15h 20m
    0
    2:30 PM
    St. Louis, MO
    Gateway Station
    6:50 AM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $88

    Fastest Flights Saturday

  • United Airlines
    4h 58m
    0
    7:30 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:28 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $210
  • United Airlines
    6h 28m
    0
    6:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:28 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $210
  • United Airlines
    8h 23m
    0
    6:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    3:23 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $210
  • Frontier Airlines
    15h 26m
    0
    4:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    8:52 AM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from $261
  • Frontier Airlines
    26h 52m
    0
    7:59 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    11:51 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from $242
  • Fastest Buses Saturday

  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $72
  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $71
  • FlixBus
    14h 15m
    0
    11:30 PM
    St. Louis, MO
    Gateway Station
    2:45 PM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $71
  • FlixBus
    15h 20m
    0
    2:30 PM
    St. Louis, MO
    Gateway Station
    6:50 AM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $72

    Fastest Buses Sunday

  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $79
  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $80
  • FlixBus
    14h 15m
    0
    11:30 PM
    St. Louis, MO
    Gateway Station
    2:45 PM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $79
  • FlixBus
    15h 20m
    0
    2:30 PM
    St. Louis, MO
    Gateway Station
    6:50 AM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $80

    Fastest Buses Tuesday

  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $67
  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $67
  • FlixBus
    15h 20m
    0
    2:30 PM
    St. Louis, MO
    Gateway Station
    6:50 AM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $67

    Fastest Buses Wednesday

  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $69
  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $69
  • Greyhound US
    18h 50m
    0
    2:05 PM
    St. Louis, MO
    Gateway Station
    9:55 AM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $70

    Fastest Flights Thursday

  • United Airlines
    4h 58m
    0
    7:30 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    1:28 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $183
  • United Airlines
    6h 22m
    0
    1:08 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    8:30 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from $183
  • Alaska Airlines
    9h 47m
    0
    6:00 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    4:47 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Alaska Airlines
    Economy
    from $585
  • Frontier Airlines
    16h 14m
    0
    7:24 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    12:38 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from $213
  • Frontier Airlines
    23h 37m
    0
    7:24 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    8:01 PM
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from $181
  • Fastest Buses Thursday

  • Greyhound US
    13h 10m
    0
    8:45 AM
    St. Louis, MO
    Gateway Station
    10:55 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $88
  • Greyhound US
    13h 50m
    0
    2:00 AM
    St. Louis, MO
    Gateway Station
    4:50 PM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $87
  • FlixBus
    14h 15m
    0
    11:30 PM
    St. Louis, MO
    Gateway Station
    2:45 PM
    Detroit
    Central Bus Station
    0
    FlixBus
    Economy
    $87
  • Greyhound US
    18h 50m
    0
    2:05 PM
    St. Louis, MO
    Gateway Station
    9:55 AM
    Detroit
    Central Bus Station
    0
    Greyhound US
    Economy
    $87
Here you will find all operators and timetables for a Bus from St. Louis, MO to Detroit

What are the most popular stations in St. Louis, MO and Detroit?

In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Detroit you will be arriving at Central Bus Station, Amtrak or Park Avenue, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Detroit from St. Louis, MO? With 6 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Detroit, you can pay as low as $67 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Detroit in just 4h 58m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Detroit are Greyhound US, FlixBus and United Airlines, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in St. Louis, MO and Detroit is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Windsor, ON, and look at flights from St. Louis Lambert Airport, and landing at Detroit Metropolitan Wayne County Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from St. Louis, MO to Detroit?

The most popular companies between St. Louis, MO and Detroit, are Greyhound US, FlixBus and United Airlines. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US and FlixBus

Airlines: United Airlines, Frontier Airlines and Alaska Airlines

All you need to know when you travel from St. Louis, MO to Detroit

Check all information on comfort and services on all modes of transports from St. Louis, MO to Detroit. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from St. Louis, MO to Detroit

How can I reach Detroit from St. Louis, MO?

Every day, there are on average 6 connections between Flight and Bus, with which you can get to Detroit from St. Louis, MO.

How far is Detroit from St. Louis, MO?

The distance between St. Louis, MO and Detroit is 454.7 miles.

What is the most ecofriendly mode of transport between St. Louis, MO and Detroit?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 124 kgs, and a flight 180 kgs.

What is the cheapest mode of transport from St. Louis, MO to Detroit?

You can get to Detroit with just $67 by taking a Bus from Greyhound US.

What is the fastest way to get from St. Louis, MO to Detroit?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Detroit in just 4h 58m with a Flight from United Airlines.

More routes to St. Louis, MO and to Detroit

Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Detroit. Simply click on a connection, and you’ll find all the details about the route!

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