Bus from St. Louis, MO to Detroit from $69

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Compare all timetables for the bus from St. Louis, MO to Detroit

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Detroit from various bus operators like Greyhound US or FlixBus for the next days.

today
$90
tomorrow
Thursday
$96
Friday
Saturday
Sunday
$81
Monday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 13h 10m 8:45 AM St. Louis, MO Gateway Station 10:55 PM Detroit Central Bus Station  Economy $90
Greyhound US 19h 0m 1:55 PM St. Louis, MO Gateway Station 9:55 AM Detroit Central Bus Station  Economy $96

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 13h 10m 8:45 AM St. Louis, MO Gateway Station 10:55 PM Detroit Central Bus Station  Economy $96
FlixBus 19h 30m 9:30 AM St. Louis, MO Gateway Station 6:00 AM Detroit Central Bus Station  Economy $96
FlixBus 14h 15m 11:30 PM St. Louis, MO Gateway Station 2:45 PM Detroit Central Bus Station  Economy $96
Greyhound US 19h 0m 1:55 PM St. Louis, MO Gateway Station 9:55 AM Detroit Central Bus Station  Economy $97
  • Did you know that if you travel from St. Louis, MO to Detroit via Chicago, you can save more than $16? You can find the corresponding connections below.
    • Busbud
      19h 30m
      0
      9:30 AM
      St. Louis, MO
      Gateway Station
      4:30 PM
      Chicago
      Downtown Bus Station
      0
      Busbud
      Economy
      $45
      • Waiting Time 2h 55m
    • Busbud
      9h 35m
      0
      7:25 PM
      Chicago
      95th Red Line Station
      6:00 AM
      Detroit
      Central Bus Station
      0
      Busbud
      Economy
      $35
    Travel time is 5h 20m longer, but you will save $16

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 15m 11:30 PM St. Louis, MO Gateway Station 2:45 PM Detroit Central Bus Station  Economy $81
FlixBus 19h 30m 9:30 AM St. Louis, MO Gateway Station 6:00 AM Detroit Central Bus Station  Economy $82
Greyhound US 19h 0m 1:55 PM St. Louis, MO Gateway Station 9:55 AM Detroit Central Bus Station  Economy $83
Greyhound US 13h 10m 8:45 AM St. Louis, MO Gateway Station 10:55 PM Detroit Central Bus Station  Economy $84

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Detroit is $69 on 1/8/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between St. Louis, MO and Detroit

See here how frequent the connections between St. Louis, MO and Detroit are, during different times and days of the week.
Sunday is the busiest day, with more than 8 daily buses from St. Louis, MO to Detroit. Tuesday has instead the fewest connections, with only 4 daily coaches between St. Louis, MO and Detroit.
The busiest time of the day is the Morning, with 10 buses from St. Louis, MO to Detroit, while Evening sees the fewest connections between St. Louis, MO and Detroit, with 4 offers.

Facts about the bus from St. Louis, MO to Detroit

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from St. Louis, MO to Detroit in one click! Book your bus ticket from St. Louis, MO to Detroit starting from $69!

Cheapest Bus $69
Fastest Bus 14h 10m
Earliest Bus 8:45 AM
Latest Bus 11:30 PM
Daily Bus Routes 6 Ø
Distance 454.7 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Detroit

Every day, 6 buses from 2 bus companies leave St. Louis, MO for Detroit: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/16/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
$90
Wednesday 12/17
Thursday 12/18
$96
Friday 12/19
Saturday 12/20
Sunday 12/21
$81
Monday 12/22
Tuesday 12/23
$109
Wednesday 12/24
Thursday 12/25
$99
Friday 12/26
Saturday 12/27
Sunday 12/28
$96
Monday 12/29
$97
Tuesday 12/30
$83
Wednesday 12/31
Thursday 01/01
$94
Friday 01/02
$96
Saturday 01/03
Sunday 01/04
Monday 01/05
$76
Tuesday 01/06
Wednesday 01/07
Thursday 01/08
$69
Friday 01/09
Saturday 01/10

The cheapest time to travel from St. Louis, MO to Detroit

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Detroit, for the next 30 days.
With a price starting from $69, Thursday is the cheapest day for a bus from St. Louis, MO to Detroit. Tuesday instead is the most expensive day with prices starting from $83.
Evening is the cheapest day time for bus tickets from St. Louis, MO to Detroit, with $81. Afternoon is the most expensive time of the day with prices starting from $83.

How to save money travelling from St. Louis, MO to Detroit

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Detroit in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Detroit, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Detroit are also emptier.

Beloved bus companies from St. Louis, MO to Detroit

These are the most booked bus companies between St. Louis, MO to Detroit from our users.

Greyhound US from St. Louis, MO to Detroit

Greyhound US

Here you will find the key facts about the Greyhound US bus route St. Louis, MO to Detroit:

Cheapest Price $83
Fastest Bus 14h 10m
Earliest Bus 8:45 AM
Last Bus 1:55 PM
Daily Connections 4 Ø
Found on 12/15/2025

FlixBus from St. Louis, MO to Detroit

FlixBus

Here you will find the key facts about the FlixBus bus route St. Louis, MO to Detroit:

Cheapest Price $81
Fastest Bus 15h 15m
Earliest Bus 9:30 AM
Last Bus 11:30 PM
Daily Connections 4 Ø
Found on 11/24/2025

All bus stations and stops in St. Louis, MO and Detroit

In the map below, you can see where to find all bus stations in St. Louis, MO and Detroit.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from St. Louis, MO to Detroit? Compare all modes of transports from St. Louis, MO to Detroit.

Service and Comfort on the bus from St. Louis, MO to Detroit

Want to know which seat classes are available on the buses from St. Louis, MO to Detroit? Or which bus companies serve the route St. Louis, MO to Detroit? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Detroit bus

How much does a St. Louis, MO Detroit bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $69 and takes 15h 15m to reach Detroit. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Detroit?

This route is offered by 2 companies with a range of ticket prices between $69 and $115. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Detroit.

On average, how many connections are available from St. Louis, MO to Detroit each day?

Every day, the St. Louis, MO to Detroit bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Detroit take?

The fastest bus from St. Louis, MO to Detroit is offered by Greyhound US and takes 14h 10m. Bus tickets for this connection cost $115. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Detroit?

The earliest bus arriving in Detroit from St. Louis, MO starts at 8:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Detroit?

The latest bus trip departing from St. Louis, MO for Detroit starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Detroit route?

When traveling by bus from St. Louis, MO to Detroit, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Detroit?

You can check all the direct connections between St. Louis, MO and Detroit by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Detroit bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Detroit bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Detroit bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Detroit on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Detroit?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between St. Louis, MO and Detroit. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Detroit?

Prices and availability for 6 trips between St. Louis, MO and Detroit change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Detroit

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Detroit

Here’s an overview of the most popular bus routes to St. Louis, MO and to Detroit. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to St. Louis, MO and to Detroit
CheckMyBus › Buses in USA › Bus to St. Louis, MO › Bus to Detroit

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