Bus St. Louis, MO to Detroit: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Detroit

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Detroit from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Wednesday

Thursday

Friday

Saturday

Sunday

from $105

Cheapest bus trips Sunday

Prices are for one way and one person

Greyhound US

14h 10m

0

8:45 AM

St. Louis, MO
Gateway Station

10:55 PM

Detroit
Central Bus Station

0

Economy

$105

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/13/2025 8:45:00 AM to Central Bus Station, Detroit (USA) arriving at 7/13/2025 10:55:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 14h 10m
FlixBus

15h 15m

0

11:30 PM

St. Louis, MO
Gateway Station

2:45 PM

Detroit
Central Bus Station

0

Economy

$105

A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 7/13/2025 11:30:00 PM to Central Bus Station, Detroit (USA) arriving at 7/14/2025 2:45:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 15h 15m
Greyhound US

20h 0m

0

1:55 PM

St. Louis, MO
Gateway Station

9:55 AM

Detroit
Central Bus Station

0

Economy

$109

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/13/2025 1:55:00 PM to Central Bus Station, Detroit (USA) arriving at 7/14/2025 9:55:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 20h 0m
Greyhound US

15h 15m

0

2:30 AM

St. Louis, MO
Gateway Station

5:45 PM

Detroit
Central Bus Station

0

Economy

$111

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/13/2025 2:30:00 AM to Central Bus Station, Detroit (USA) arriving at 7/13/2025 5:45:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 15h 15m
FlixBus

20h 15m

0

9:45 AM

St. Louis, MO
Gateway Station

6:00 AM

Detroit
Central Bus Station

0

Economy

$113

A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 7/13/2025 9:45:00 AM to Central Bus Station, Detroit (USA) arriving at 7/14/2025 6:00:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 20h 15m
Did you know that if you travel from St. Louis, MO to Detroit via Chicago, you can save more than $39? You can find the corresponding connections below.
- Busbud
  
  16h 15m
  
  0
  
  11:30 PM
  
  St. Louis, MO
  Gateway Station
  
  5:45 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $38
  
  A Bus from Busbud goes from Gateway Station, St. Louis, MO (USA) at 7/14/2025 11:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 7/15/2025 5:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 6h 15m
- Busbud
  
  8h 50m
  
  0
  
  6:55 AM
  
  Chicago
  Downtown Bus Station
  
  3:45 PM
  
  Detroit
  Central Bus Station
  
  0
  
  Economy
  
  $28
  
  A Bus from Busbud goes from Downtown Bus Station, Chicago (USA) at 7/15/2025 6:55:00 AM to Central Bus Station, Detroit (USA) arriving at 7/15/2025 3:45:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 8h 50m
Travel time is 2h 5m longer, but you will save $39

Facts about the bus from St. Louis, MO to Detroit

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from St. Louis, MO to Detroit in one click! Book your bus ticket from St. Louis, MO to Detroit starting from $105!

Cheapest Bus	$105
Fastest Bus	14h 10m
Earliest Bus	2:30 AM
Latest Bus	11:30 PM
Daily Bus Routes	5 Ø
Distance	454.7 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Detroit

Every day, 5 buses from 2 bus companies leave St. Louis, MO for Detroit: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/07/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/06

Monday 07/07

Tuesday 07/08

Wednesday 07/09

Thursday 07/10

Friday 07/11

Saturday 07/12

Sunday 07/13

$105

Monday 07/14

Tuesday 07/15

Wednesday 07/16

$74

Thursday 07/17

Friday 07/18

$73

Saturday 07/19

Sunday 07/20

Monday 07/21

Tuesday 07/22

Wednesday 07/23

Thursday 07/24

Friday 07/25

Saturday 07/26

Sunday 07/27

Monday 07/28

Tuesday 07/29

Wednesday 07/30

Thursday 07/31

$67

Friday 08/01

Saturday 08/02

How to save money travelling from St. Louis, MO to Detroit

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Detroit in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Detroit, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Detroit are also emptier.

Beloved bus companies from St. Louis, MO to Detroit

These are the most booked bus companies between St. Louis, MO to Detroit from our users.

Greyhound US from St. Louis, MO to Detroit

Here you will find the key facts about the Greyhound US bus route St. Louis, MO to Detroit:

Cheapest Price	$105
Fastest Bus	14h 10m
Earliest Bus	2:30 AM
Last Bus	1:55 PM
Daily Connections	3 Ø
Found on	7/5/2025

FlixBus from St. Louis, MO to Detroit

Here you will find the key facts about the FlixBus bus route St. Louis, MO to Detroit:

Cheapest Price	$105
Fastest Bus	15h 15m
Earliest Bus	9:45 AM
Last Bus	11:30 PM
Daily Connections	2 Ø
Found on	7/5/2025

All bus stations and stops in St. Louis, MO and Detroit

In the map below, you can see where to find all bus stations in St. Louis, MO and Detroit.

Lindbergh @ Hackberry NB Bus Stop

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Gateway Station

S 15th St 430

Central Bus Station

Howard St 1001

Amtrak

W Baltimore Ave 78

VA Medical Center Blue Deck

East Canfield Street (between John R. and Brush St.) 225

Park Avenue

Livernois & Chicago Bus Stop

Service and Comfort on the bus from St. Louis, MO to Detroit

Want to know which seat classes are available on the buses from St. Louis, MO to Detroit? Or which bus companies serve the route St. Louis, MO to Detroit? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Detroit bus

How much does a St. Louis, MO Detroit bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $105 and takes 14h 10m to reach Detroit. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Detroit?

This route is offered by 2 companies with a range of ticket prices between $105 and $113. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Detroit.

On average, how many connections are available from St. Louis, MO to Detroit each day?

Every day, the St. Louis, MO to Detroit bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Detroit take?

The fastest bus from St. Louis, MO to Detroit is offered by Greyhound US and takes 14h 10m. Bus tickets for this connection cost $105. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Detroit?

The earliest bus arriving in Detroit from St. Louis, MO starts at 2:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Detroit?

The latest bus trip departing from St. Louis, MO for Detroit starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Detroit route?

When traveling by bus from St. Louis, MO to Detroit, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Detroit?

You can check all the direct connections between St. Louis, MO and Detroit by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Detroit bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Detroit bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Detroit bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Detroit on your planned travel date.

Available seat classes which are offered on the bus route St. Louis, MO to Detroit

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Detroit

Here’s an overview of the most popular bus routes to St. Louis, MO and to Detroit. Simply click on the connection of your choice, and you will find all the details about your bus route!