Bus Biloxi, MS to Chicago - Compare all Companies

Compare all timetables for the bus from Biloxi, MS to Chicago

Here is a selection of the cheapest bus trips from the schedule from Biloxi, MS to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today

$132

tomorrow

$135

Wednesday

Thursday

$124

Friday

Saturday

$138

Sunday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 10m	9:55 AM	Biloxi, MS	Transit Center	11:05 AM	Chicago	95th Red Line Station		Economy	$132	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/19/2026 9:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/20/2026 11:05:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 25h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 10m	9:55 AM	Biloxi, MS	Transit Center	11:05 AM	Chicago	95th Red Line Station	Economy	$135	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/20/2026 9:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/21/2026 11:05:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 25h 10m
Greyhound US	28h 15m	9:55 AM	Biloxi, MS	Transit Center	2:10 PM	Chicago	Union Station	Economy	$137	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/20/2026 9:55:00 AM to Union Station, Chicago (USA) arriving at 1/21/2026 2:10:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 28h 15m
Greyhound US	40h 55m	3:05 PM	Biloxi, MS	Transit Center	8:00 AM	Chicago	Union Station	Economy	$137	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/20/2026 3:05:00 PM to Union Station, Chicago (USA) arriving at 1/22/2026 8:00:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 40h 55m
Greyhound US	25h 35m	9:55 AM	Biloxi, MS	Transit Center	11:30 AM	Chicago	Downtown Bus Station	Economy	$139	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/20/2026 9:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 1/21/2026 11:30:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 25h 35m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 10m	9:55 AM	Biloxi, MS	Transit Center	11:05 AM	Chicago	95th Red Line Station		Economy	$124	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/22/2026 9:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/23/2026 11:05:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 25h 10m
	FlixBus	42h 40m	9:15 PM	Biloxi, MS	Transit Center	3:55 PM	Chicago	95th Red Line Station		Economy	$124	A Bus from FlixBus goes from Transit Center, Biloxi, MS (USA) at 1/22/2026 9:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/24/2026 3:55:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 42h 40m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	42h 40m	9:15 PM	Biloxi, MS	Transit Center	3:55 PM	Chicago	95th Red Line Station	Economy	$138	A Bus from FlixBus goes from Transit Center, Biloxi, MS (USA) at 1/24/2026 9:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/26/2026 3:55:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 42h 40m
Greyhound US	28h 15m	9:55 AM	Biloxi, MS	Transit Center	2:10 PM	Chicago	Union Station	Economy	$142	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/24/2026 9:55:00 AM to Union Station, Chicago (USA) arriving at 1/25/2026 2:10:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 28h 15m
Greyhound US	32h 45m	3:05 PM	Biloxi, MS	Transit Center	11:50 PM	Chicago	95th Red Line Station	Economy	$143	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/24/2026 3:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/25/2026 11:50:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 32h 45m
Greyhound US	25h 10m	9:55 AM	Biloxi, MS	Transit Center	11:05 AM	Chicago	95th Red Line Station	Economy	$144	A Bus from Greyhound US goes from Transit Center, Biloxi, MS (USA) at 1/24/2026 9:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/25/2026 11:05:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 25h 10m
FlixBus	43h 15m	9:15 PM	Biloxi, MS	Transit Center	4:30 PM	Chicago	Downtown Bus Station	Economy	$148	A Bus from FlixBus goes from Transit Center, Biloxi, MS (USA) at 1/24/2026 9:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 1/26/2026 4:30:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 43h 15m

Best Price Offer: The price for the cheapest bus from Biloxi, MS to Chicago is $124 on 1/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Biloxi, MS and Chicago

See here how frequent the connections between Biloxi, MS and Chicago are, during different times and days of the week.

Saturday is the busiest day, with more than 8 daily buses from Biloxi, MS to Chicago. Monday has instead the fewest connections, with only 1 daily coaches between Biloxi, MS and Chicago.

The busiest time of the day is the Morning, with 8 buses from Biloxi, MS to Chicago, while Evening sees the fewest connections between Biloxi, MS and Chicago, with 3 offers.

Facts about the bus from Biloxi, MS to Chicago

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from Biloxi, MS to Chicago in one click! Book your bus ticket from Biloxi, MS to Chicago starting from $124!

Cheapest Bus	$124
Fastest Bus	25h 10m
Earliest Bus	9:55 AM
Latest Bus	9:15 PM
Daily Bus Routes	3 Ø
Distance	796.5 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Biloxi, MS to Chicago

Every day, 3 buses from 2 bus companies leave Biloxi, MS for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$132

Tuesday 01/20

$135

Wednesday 01/21

Thursday 01/22

$124

Friday 01/23

Saturday 01/24

$142

Sunday 01/25

Monday 01/26

Tuesday 01/27

$126

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from Biloxi, MS to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Biloxi, MS to Chicago, for the next 30 days.

With a price starting from $124, Thursday is the cheapest day for a bus from Biloxi, MS to Chicago. Saturday instead is the most expensive day with prices starting from $138.

Evening is the cheapest day time for bus tickets from Biloxi, MS to Chicago, with $124. Afternoon is the most expensive time of the day with prices starting from $137.

How to save money travelling from Biloxi, MS to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Biloxi, MS to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Biloxi, MS to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Biloxi, MS to Chicago are also emptier.

All bus stations and stops in Biloxi, MS and Chicago

In the map below, you can see where to find all bus stations in Biloxi, MS and Chicago.

Transit Center

Dr Martin Luther King Jr Blvd 820

Love's Travel Stop

Cedar Lake Rd 11347

Point Cadet

Myrtle St

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Biloxi, MS to Chicago

Want to know which seat classes are available on the buses from Biloxi, MS to Chicago? Or which bus companies serve the route Biloxi, MS to Chicago? Below you will find answers to your questions.

FAQs about the Biloxi, MS to Chicago bus

How much does a Biloxi, MS Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $124 and takes 42h 40m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Biloxi, MS to Chicago?

This route is offered by 2 companies with a range of ticket prices between $124 and $148. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Biloxi, MS to Chicago each day?

Every day, the Biloxi, MS to Chicago bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Biloxi, MS to Chicago take?

The fastest bus from Biloxi, MS to Chicago is offered by Greyhound US and takes 25h 10m. Bus tickets for this connection cost $132. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Biloxi, MS to Chicago?

The earliest bus arriving in Chicago from Biloxi, MS starts at 9:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Biloxi, MS to Chicago?

The latest bus trip departing from Biloxi, MS for Chicago starts at 9:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Biloxi, MS Chicago route?

When traveling by bus from Biloxi, MS to Chicago, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Biloxi, MS and Chicago?

You can check all the direct connections between Biloxi, MS and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Biloxi, MS to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Biloxi, MS Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Biloxi, MS Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Biloxi, MS to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Biloxi, MS to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Biloxi, MS and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Biloxi, MS to Chicago?

Prices and availability for 3 trips between Biloxi, MS and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Biloxi, MS to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Biloxi, MS and to Chicago

Here’s an overview of the most popular bus routes to Biloxi, MS and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!