Bus Cambridge, MA to Indianapolis - Compare all Companies

Compare all timetables for the bus from Cambridge, MA to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Cambridge, MA to Indianapolis from various bus operators like FlixBus for the next days.

today

tomorrow

$276

Saturday

$176

Sunday

Monday

$172

Tuesday

$194

Wednesday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	40h 0m	11:00 AM	Cambridge, MA	Alewife Station	3:00 AM	Indianapolis	Washington / Delaware		Economy	$276	A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/19/2025 11:00:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 12/21/2025 3:00:00 AM. 50 Economy ticket for $276 per person are available. Travel duration is 40h 0m
	FlixBus	31h 40m	11:00 AM	Cambridge, MA	Alewife Station	6:40 PM	Indianapolis	Central Bus Station		Economy	$321	A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/19/2025 11:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 12/20/2025 6:40:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 31h 40m

Did you know that if you travel from Cambridge, MA to Indianapolis via Boston, MA, you can save more than $53? You will find the corresponding connections below.
- FlixBus
  
  Save more than 19%
  
  25h 30m
  
  Cambridge, MA
  
  3 mi
  
  1:30 AM
  
  Boston, MA
  Allston
  
  3:00 AM
  
  Indianapolis
  Washington / Delaware
  
  0 mi
  
  Economy
  
  $223
  
  A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/19/2025 1:30:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 12/20/2025 3:00:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 25h 30m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	40h 0m	11:00 AM	Cambridge, MA	Alewife Station	3:00 AM	Indianapolis	Washington / Delaware		Economy	$176	A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/20/2025 11:00:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 12/22/2025 3:00:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 40h 0m
	FlixBus	31h 40m	11:00 AM	Cambridge, MA	Alewife Station	6:40 PM	Indianapolis	Central Bus Station		Economy	$207	A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/20/2025 11:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 31h 40m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	40h 0m	11:00 AM	Cambridge, MA	Alewife Station	3:00 AM	Indianapolis	Washington / Delaware		Economy	$172	A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/22/2025 11:00:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 12/24/2025 3:00:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 40h 0m
	FlixBus	31h 40m	11:00 AM	Cambridge, MA	Alewife Station	6:40 PM	Indianapolis	Central Bus Station		Economy	$185	A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/22/2025 11:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 12/23/2025 6:40:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 31h 40m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	40h 0m	11:00 AM	Cambridge, MA	Alewife Station	3:00 AM	Indianapolis	Washington / Delaware		Economy	$194	A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/23/2025 11:00:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 12/25/2025 3:00:00 AM. 50 Economy ticket for $194 per person are available. Travel duration is 40h 0m
	FlixBus	31h 40m	11:00 AM	Cambridge, MA	Alewife Station	6:40 PM	Indianapolis	Central Bus Station		Economy	$229	A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/23/2025 11:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 12/24/2025 6:40:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 31h 40m

Did you know that if you travel from Cambridge, MA to Indianapolis via Pittsburgh, you can save more than $27? You can find the corresponding connections below.
- FlixBus
  
  46h 45m
  
  0
  
  11:00 AM
  
  Cambridge, MA
  Alewife Station
  
  6:30 AM
  
  Pittsburgh
  Grant Street Transportation Center
  
  0
  
  Economy
  
  $95
  
  A Bus from FlixBus goes from Alewife Station, Cambridge, MA (USA) at 12/24/2025 11:00:00 AM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/25/2025 6:30:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 19h 30m
- FlixBus
  
  8h 10m
  
  0
  
  1:35 AM
  
  Pittsburgh
  Grant Street Transportation Center
  
  9:45 AM
  
  Indianapolis
  Central Bus Station
  
  0
  
  Economy
  
  $72
  
  A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/26/2025 1:35:00 AM to Central Bus Station, Indianapolis (USA) arriving at 12/26/2025 9:45:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 8h 10m
Travel time is 15h 5m longer, but you will save $27

Best Price Offer: The price for the cheapest bus from Cambridge, MA to Indianapolis is $158 on 12/16/2025. Flexible travelers save on ticket prices.

Facts about the bus from Cambridge, MA to Indianapolis

Compare all providers like FlixBus that travel 3 times every day by bus from Cambridge, MA to Indianapolis in one click! Book your bus ticket from Cambridge, MA to Indianapolis starting from $158!

Cheapest Bus	$158
Fastest Bus	31h 40m
Earliest Bus	11:00 AM
Latest Bus	11:00 AM
Daily Bus Routes	3 Ø
Distance	803.1 miles
Bus Companies	FlixBus

Cheapest bus connections from Cambridge, MA to Indianapolis

Every day, 3 buses from 1 bus companies leave Cambridge, MA for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$276

Saturday 12/20

$176

Sunday 12/21

Monday 12/22

$172

Tuesday 12/23

$194

Wednesday 12/24

Thursday 12/25

Friday 12/26

$271

Saturday 12/27

$160

Sunday 12/28

$173

Monday 12/29

$176

Tuesday 12/30

$168

Wednesday 12/31

$170

Thursday 01/01

Friday 01/02

$158

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

How to save money travelling from Cambridge, MA to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cambridge, MA to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cambridge, MA to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cambridge, MA to Indianapolis are also emptier.

All bus stations and stops in Cambridge, MA and Indianapolis

In the map below, you can see where to find all bus stations in Cambridge, MA and Indianapolis.

Alewife Station

Rindge Ave 351

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

BP Gas Station 70/91

N Post Rd 2102

Service and Comfort on the bus from Cambridge, MA to Indianapolis

Want to know which seat classes are available on the buses from Cambridge, MA to Indianapolis? Or which bus companies serve the route Cambridge, MA to Indianapolis? Below you will find answers to your questions.

FAQs about the Cambridge, MA to Indianapolis bus

How much does a Cambridge, MA Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $158 and takes 40h 0m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Cambridge, MA to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $158 and $321. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Cambridge, MA to Indianapolis each day?

Every day, the Cambridge, MA to Indianapolis bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cambridge, MA to Indianapolis take?

The fastest bus from Cambridge, MA to Indianapolis is offered by FlixBus and takes 31h 40m. Bus tickets for this connection cost $321. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cambridge, MA to Indianapolis?

The earliest bus arriving in Indianapolis from Cambridge, MA starts at 11:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cambridge, MA to Indianapolis?

The latest bus trip departing from Cambridge, MA for Indianapolis starts at 11:00 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cambridge, MA Indianapolis route?

When traveling by bus from Cambridge, MA to Indianapolis, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cambridge, MA and Indianapolis?

You can check all the direct connections between Cambridge, MA and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Cambridge, MA to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cambridge, MA Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cambridge, MA Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cambridge, MA to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from Cambridge, MA to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Cambridge, MA and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Cambridge, MA to Indianapolis?

Prices and availability for 3 trips between Cambridge, MA and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Cambridge, MA to Indianapolis

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cambridge, MA and to Indianapolis

Here’s an overview of the most popular bus routes to Cambridge, MA and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!