Which bus from Cambridge, MA to Indianapolis is the cheapest?

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Compare all timetables for the bus from Cambridge, MA to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Cambridge, MA to Indianapolis from various bus operators like FlixBus for the next days.

today
tomorrow
$121
Sunday
$178
Monday
$167
Tuesday
$231
Wednesday
Thursday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 31h 40m 11:00 AM Cambridge, MA Alewife Station 6:40 PM Indianapolis Central Bus Station  Economy $121
FlixBus 40h 0m 11:00 AM Cambridge, MA Alewife Station 3:00 AM Indianapolis Downtown Transit Center  Economy $123
  • Did you know that if you travel from Cambridge, MA to Indianapolis via Pittsburgh, you can save more than $12? You can find the corresponding connections below.
    • Busbud
      46h 45m
      0
      11:00 AM
      Cambridge, MA
      Alewife Station
      6:30 AM
      Pittsburgh
      Grant Street Transportation Center
      0
      Busbud
      Economy
      $64
      • Waiting Time 19h 5m
    • Busbud
      8h 10m
      0
      1:35 AM
      Pittsburgh
      Grant Street Transportation Center
      9:45 AM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $45
    Travel time is 15h 5m longer, but you will save $12

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 31h 40m 11:00 AM Cambridge, MA Alewife Station 6:40 PM Indianapolis Central Bus Station  Economy $178
  • Did you know that if you travel from Cambridge, MA to Indianapolis via Pittsburgh, you can save more than $70? You can find the corresponding connections below.
    • Busbud
      46h 45m
      0
      11:00 AM
      Cambridge, MA
      Alewife Station
      6:30 AM
      Pittsburgh
      Grant Street Transportation Center
      0
      Busbud
      Economy
      $65
      • Waiting Time 19h 5m
    • Busbud
      8h 10m
      0
      1:35 AM
      Pittsburgh
      Grant Street Transportation Center
      9:45 AM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $42
    Travel time is 15h 5m longer, but you will save $70

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 31h 40m 11:00 AM Cambridge, MA Alewife Station 6:40 PM Indianapolis Central Bus Station  Economy $167
  • Did you know that if you travel from Cambridge, MA to Indianapolis via Brookline, MA, you can save more than $6? You will find the corresponding connections below.
    • Save more than 4%
      31h 5m
      Cambridge, MA
      3 mi
      8:55 PM
      Brookline, MA
      Bus Stop
      4:00 AM
      Indianapolis
      Central Bus Station
      0 mi
      Economy
      $161
  • Did you know that if you travel from Cambridge, MA to Indianapolis via Pittsburgh, you can save more than $59? You can find the corresponding connections below.
    • Busbud
      46h 45m
      0
      11:00 AM
      Cambridge, MA
      Alewife Station
      6:30 AM
      Pittsburgh
      Grant Street Transportation Center
      0
      Busbud
      Economy
      $65
      • Waiting Time 19h 5m
    • Busbud
      8h 10m
      0
      1:35 AM
      Pittsburgh
      Grant Street Transportation Center
      9:45 AM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $42
    Travel time is 15h 5m longer, but you will save $59

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 40h 0m 11:00 AM Cambridge, MA Alewife Station 3:00 AM Indianapolis Washington / Delaware  Economy $231
FlixBus 31h 40m 11:00 AM Cambridge, MA Alewife Station 6:40 PM Indianapolis Central Bus Station  Economy $233
  • Did you know that if you travel from Cambridge, MA to Indianapolis via Pittsburgh, you can save more than $123? You can find the corresponding connections below.
    • Busbud
      46h 45m
      0
      11:00 AM
      Cambridge, MA
      Alewife Station
      6:30 AM
      Pittsburgh
      Grant Street Transportation Center
      0
      Busbud
      Economy
      $65
      • Waiting Time 19h 5m
    • Busbud
      8h 10m
      0
      1:35 AM
      Pittsburgh
      Grant Street Transportation Center
      9:45 AM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $42
    Travel time is 15h 5m longer, but you will save $123

Best Price Offer: The price for the cheapest bus from Cambridge, MA to Indianapolis is $108 on 2/17/2026. Flexible travelers save on ticket prices.


Facts about the bus from Cambridge, MA to Indianapolis

Compare all providers like FlixBus that travel 2 times every day by bus from Cambridge, MA to Indianapolis in one click! Book your bus ticket from Cambridge, MA to Indianapolis starting from $108!

Cheapest Bus $108
Fastest Bus 31h 40m
Earliest Bus 11:00 AM
Latest Bus 11:00 AM
Daily Bus Routes 2 Ø
Distance 803.1 miles
Bus Companies FlixBus

Cheapest bus connections from Cambridge, MA to Indianapolis

Every day, 2 buses from 1 bus companies leave Cambridge, MA for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
$262
Sunday 02/08
$178
Monday 02/09
$167
Tuesday 02/10
$231
Wednesday 02/11
Thursday 02/12
Friday 02/13
$195
Saturday 02/14
$126
Sunday 02/15
$129
Monday 02/16
Tuesday 02/17
$108
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
$116
Sunday 02/22
$127
Monday 02/23
$123
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

How to save money travelling from Cambridge, MA to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cambridge, MA to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cambridge, MA to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cambridge, MA to Indianapolis are also emptier.

All bus stations and stops in Cambridge, MA and Indianapolis

In the map below, you can see where to find all bus stations in Cambridge, MA and Indianapolis.

Service and Comfort on the bus from Cambridge, MA to Indianapolis

Want to know which seat classes are available on the buses from Cambridge, MA to Indianapolis? Or which bus companies serve the route Cambridge, MA to Indianapolis? Below you will find answers to your questions.

FAQs about the Cambridge, MA to Indianapolis bus

How much does a Cambridge, MA Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $108 and takes 31h 40m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Cambridge, MA to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $108 and $263. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Cambridge, MA to Indianapolis each day?

Every day, the Cambridge, MA to Indianapolis bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cambridge, MA to Indianapolis take?

The fastest bus from Cambridge, MA to Indianapolis is offered by FlixBus and takes 31h 40m. Bus tickets for this connection cost $121. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cambridge, MA to Indianapolis?

The earliest bus arriving in Indianapolis from Cambridge, MA starts at 11:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cambridge, MA to Indianapolis?

The latest bus trip departing from Cambridge, MA for Indianapolis starts at 11:00 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cambridge, MA Indianapolis route?

When traveling by bus from Cambridge, MA to Indianapolis, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cambridge, MA and Indianapolis?

You can check all the direct connections between Cambridge, MA and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Cambridge, MA to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cambridge, MA Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cambridge, MA Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cambridge, MA to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from Cambridge, MA to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Cambridge, MA and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Cambridge, MA to Indianapolis?

Prices and availability for 2 trips between Cambridge, MA and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Cambridge, MA to Indianapolis

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cambridge, MA and to Indianapolis

Here’s an overview of the most popular bus routes to Cambridge, MA and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus Miami - Cambridge, MA Bus Miami - Cambridge, MA
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From Charleston, SC to Indianapolis bus From Charleston, SC to Indianapolis bus
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Bus to Indianapolis from Eugene, OR Bus to Indianapolis from Eugene, OR
Popular Airport Shuttles to Cambridge, MA and to Indianapolis
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