Compare all timetables for the bus from Greenville, SC to Indianapolis
Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Indianapolis from various bus operators like FlixBus or Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 25m | 1:20 PM | Greenville, SC | Woodruff Rd | 4:45 AM | Indianapolis | Central Bus Station | Economy | $104 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/22/2026 1:20:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/23/2026 4:45:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 15h 25m
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| FlixBus | 16h 25m | 7:40 PM | Greenville, SC | Woodruff Rd | 12:05 PM | Indianapolis | Central Bus Station | Economy | $104 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/22/2026 7:40:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/23/2026 12:05:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 16h 25m
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| FlixBus | 23h 25m | 10:00 PM | Greenville, SC | Woodruff Rd | 9:25 PM | Indianapolis | Washington / Delaware | Economy | $104 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/22/2026 10:00:00 PM to Washington / Delaware, Indianapolis (USA) arriving at 3/23/2026 9:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 23h 25m
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| Greyhound US | 19h 10m | 2:45 PM | Greenville, SC | Woodruff Rd | 9:55 AM | Indianapolis | Central Bus Station | Economy | $104 |
A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/22/2026 2:45:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/23/2026 9:55:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 19h 10m
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| Greyhound US | 17h 40m | 2:45 PM | Greenville, SC | Woodruff Rd | 8:25 AM | Indianapolis | Washington / Delaware | Economy | $104 |
A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/22/2026 2:45:00 PM to Washington / Delaware, Indianapolis (USA) arriving at 3/23/2026 8:25:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 17h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 25m | 1:20 PM | Greenville, SC | Woodruff Rd | 4:45 AM | Indianapolis | Central Bus Station | Economy | $91 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/24/2026 1:20:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/25/2026 4:45:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 15h 25m
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| FlixBus | 16h 25m | 7:40 PM | Greenville, SC | Woodruff Rd | 12:05 PM | Indianapolis | Central Bus Station | Economy | $91 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/24/2026 7:40:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/25/2026 12:05:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 16h 25m
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| FlixBus | 23h 25m | 10:00 PM | Greenville, SC | Woodruff Rd | 9:25 PM | Indianapolis | Downtown Transit Center | Economy | $91 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/24/2026 10:00:00 PM to Downtown Transit Center, Indianapolis (USA) arriving at 3/25/2026 9:25:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 23h 25m
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| Greyhound US | 19h 10m | 2:45 PM | Greenville, SC | Woodruff Rd | 9:55 AM | Indianapolis | Central Bus Station | Economy | $91 |
A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/24/2026 2:45:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/25/2026 9:55:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 19h 10m
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| Greyhound US | 17h 40m | 2:45 PM | Greenville, SC | Woodruff Rd | 8:25 AM | Indianapolis | Downtown Transit Center | Economy | $91 |
A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/24/2026 2:45:00 PM to Downtown Transit Center, Indianapolis (USA) arriving at 3/25/2026 8:25:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 17h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 24h 20m | 4:15 PM | Greenville, SC | Woodruff Rd | 4:35 PM | Indianapolis | Central Bus Station | Economy | $94 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/25/2026 4:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/26/2026 4:35:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 24h 20m
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| FlixBus | 23h 25m | 10:00 PM | Greenville, SC | Woodruff Rd | 9:25 PM | Indianapolis | Washington / Delaware | Economy | $94 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/25/2026 10:00:00 PM to Washington / Delaware, Indianapolis (USA) arriving at 3/26/2026 9:25:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 23h 25m
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| FlixBus | 15h 25m | 1:20 PM | Greenville, SC | Woodruff Rd | 4:45 AM | Indianapolis | Central Bus Station | Economy | $95 |
A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/25/2026 1:20:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/26/2026 4:45:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 15h 25m
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| Greyhound US | 19h 10m | 2:45 PM | Greenville, SC | Woodruff Rd | 9:55 AM | Indianapolis | Central Bus Station | Economy | $95 |
A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/25/2026 2:45:00 PM to Central Bus Station, Indianapolis (USA) arriving at 3/26/2026 9:55:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 19h 10m
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| Greyhound US | 17h 40m | 2:45 PM | Greenville, SC | Woodruff Rd | 8:25 AM | Indianapolis | Washington / Delaware | Economy | $95 |
A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/25/2026 2:45:00 PM to Washington / Delaware, Indianapolis (USA) arriving at 3/26/2026 8:25:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 17h 40m
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Best Price Offer: The price for the cheapest bus from Greenville, SC to Indianapolis is $81 on 4/2/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Greenville, SC and Indianapolis
Sunday
is the busiest day, with more than 6 daily buses from Greenville, SC to Indianapolis. Sunday has instead the fewest connections, with only 6 daily coaches between Greenville, SC and Indianapolis.
The busiest time of the day is the Afternoon, with 10 buses from Greenville, SC to Indianapolis, while Evening sees the fewest connections between Greenville, SC and Indianapolis, with 8 offers.
Facts about the bus from Greenville, SC to Indianapolis
Compare all providers like FlixBus and Greyhound US that travel 6 times every day by bus from Greenville, SC to Indianapolis in one click! Book your bus ticket from Greenville, SC to Indianapolis starting from $81!
| Cheapest Bus | $81 |
| Fastest Bus | 15h 25m |
| Earliest Bus | 1:20 PM |
| Latest Bus | 10:00 PM |
| Daily Bus Routes | 6 Ø |
| Distance | 397.5 miles |
| Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from Greenville, SC to Indianapolis
Every day, 6 buses from 2 bus companies leave Greenville, SC for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
03/15
Monday
03/16
Tuesday
03/17
Wednesday
03/18
Thursday
03/19
Friday
03/20
Saturday
03/21
Sunday
03/22
$104
Monday
03/23
Tuesday
03/24
$91
Wednesday
03/25
$94
Thursday
03/26
Friday
03/27
Saturday
03/28
Sunday
03/29
Monday
03/30
Tuesday
03/31
$86
Wednesday
04/01
Thursday
04/02
$81
Friday
04/03
Saturday
04/04
$81
Sunday
04/05
$83
Monday
04/06
Tuesday
04/07
$92
Wednesday
04/08
$91
Thursday
04/09
$83
Friday
04/10
$83
Saturday
04/11
The cheapest time to travel from Greenville, SC to Indianapolis
With a price starting from $83, Sunday is the cheapest day for a bus from Greenville, SC to Indianapolis. Wednesday instead is the most expensive day with prices starting from $91.
Evening
is the cheapest day time for bus tickets from Greenville, SC to Indianapolis, with $91. Afternoon is the most expensive time of the day with prices starting from $91.
How to save money travelling from Greenville, SC to Indianapolis
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Greenville, SC to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Indianapolis are also emptier.All bus stations and stops in Greenville, SC and Indianapolis
In the map below, you can see where to find all bus stations in Greenville, SC and Indianapolis.
Service and Comfort on the bus from Greenville, SC to Indianapolis
Want to know which seat classes are available on the buses from Greenville, SC to Indianapolis? Or which bus companies serve the route Greenville, SC to Indianapolis? Below you will find answers to your questions.
FAQs about the Greenville, SC to Indianapolis bus
How much does a Greenville, SC Indianapolis bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $81 and takes 23h 25m to reach Indianapolis. Compare offers to save money!
How much could I save by comparing buses from Greenville, SC to Indianapolis?
This route is offered by 2 companies with a range of ticket prices between $81 and $105. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.
On average, how many connections are available from Greenville, SC to Indianapolis each day?
Every day, the Greenville, SC to Indianapolis bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Greenville, SC to Indianapolis take?
The fastest bus from Greenville, SC to Indianapolis is offered by FlixBus and takes 15h 25m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Greenville, SC to Indianapolis?
The earliest bus arriving in Indianapolis from Greenville, SC starts at 1:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Greenville, SC to Indianapolis?
The latest bus trip departing from Greenville, SC for Indianapolis starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Greenville, SC Indianapolis route?
When traveling by bus from Greenville, SC to Indianapolis, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Greenville, SC and Indianapolis?
You can check all the direct connections between Greenville, SC and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.
What can I take with me on the Greenville, SC to Indianapolis bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Greenville, SC Indianapolis bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Indianapolis on your planned travel date.
How does CheckMyBus find the best bus deals from Greenville, SC to Indianapolis?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Greenville, SC and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Greenville, SC to Indianapolis?
Prices and availability for 6 trips between Greenville, SC and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Greenville, SC to Indianapolis
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Greenville, SC and to Indianapolis
Here’s an overview of the most popular bus routes to Greenville, SC and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Greenville, SC
- Buses to Greenville, SC from Aguascalientes
- Buses Atlanta, GA to Greenville, SC
- Bus from Augusta, GA to Greenville, SC
- Buses Baltimore, MD to Greenville, SC
- Bus Cincinnati - Greenville, SC
- Buses Detroit - Greenville, SC
- Bus from Doraville, GA to Greenville, SC
- Durham, NC to Greenville, SC bus
- Bus to Greenville, SC from Fort Lauderdale, FL
- Bus to Greenville, SC from Guadalajara, JC
- Bus Jacksonville, FL - Greenville, SC
- Buses to Greenville, SC from Macon, GA
- From Norcross, GA to Greenville, SC bus
- Bus from Philadelphia to Greenville, SC
- Bus San Luis Potosí - Greenville, SC
- Bus from Santiago de Queretaro to Greenville, SC
- From Syracuse, NY to Greenville, SC bus
- Bus Tampa - Greenville, SC
- Buses from Tucson, AZ to Greenville, SC
- Bus to Greenville, SC from Warner Robins, GA
- Bus Routes to Indianapolis
- Buses Birmingham, AL to Indianapolis
- Boston, MA to Indianapolis bus
- Bus Chattanooga, TN to Indianapolis
- From Dallas to Indianapolis bus
- From Dayton, OH to Indianapolis bus
- Bus from Gary, IN to Indianapolis
- From Houston to Indianapolis bus
- Bus to Indianapolis from Knoxville, TN
- Buses Madison, WI to Indianapolis
- Memphis to Indianapolis bus
- Buses Myrtle Beach, SC - Indianapolis
- From New Orleans, LA to Indianapolis bus
- Buses from Ottawa, ON to Indianapolis
- Buses to Indianapolis from Philadelphia
- Buses Phoenix, AZ to Indianapolis
- Buses Richmond, VA to Indianapolis
- From Rockford, IL to Indianapolis bus
- From South Bend, IN to Indianapolis bus
- Bus Syracuse, NY - Indianapolis
- Bus from Toronto, ON to Indianapolis
Popular Airport Shuttles to Greenville, SC and to Indianapolis
