Bus Chicago to Biloxi, MS: Compare prices and save money

Compare all timetables for the bus from Chicago to Biloxi, MS

Here is a selection of the cheapest bus trips from the schedule from Chicago to Biloxi, MS from various bus operators like Greyhound US, FlixBus or Tornado Bus Company for the next days.

today

$114

tomorrow

Wednesday

$115

Thursday

$124

Friday

Saturday

$129

Sunday

$118

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 45m	10:15 AM	Chicago	Union Station	3:00 PM	Biloxi, MS	Transit Center	Economy	$114	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 4/20/2026 10:15:00 AM to Transit Center, Biloxi, MS (USA) arriving at 4/21/2026 3:00:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 28h 45m
FlixBus	26h 0m	1:00 PM	Chicago	Downtown Bus Station	3:00 PM	Biloxi, MS	Transit Center	Economy	$114	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/20/2026 1:00:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/21/2026 3:00:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 26h 0m
Greyhound US	23h 50m	10:30 PM	Chicago	Downtown Bus Station	10:20 PM	Biloxi, MS	Transit Center	Economy	$115	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/20/2026 10:30:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/21/2026 10:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 23h 50m
Greyhound US	28h 25m	11:10 PM	Chicago	Union Station	3:35 AM	Biloxi, MS	Transit Center	Economy	$120	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 4/20/2026 11:10:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/22/2026 3:35:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 28h 25m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 50m	10:30 PM	Chicago	Downtown Bus Station	10:20 PM	Biloxi, MS	Transit Center	Economy	$115	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/22/2026 10:30:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/23/2026 10:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 23h 50m
Greyhound US	28h 25m	11:10 PM	Chicago	Union Station	3:35 AM	Biloxi, MS	Transit Center	Economy	$117	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 4/22/2026 11:10:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/24/2026 3:35:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 28h 25m
Greyhound US	28h 45m	10:50 PM	Chicago	Downtown Bus Station	3:35 AM	Biloxi, MS	Transit Center	Economy	$117	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/22/2026 10:50:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/24/2026 3:35:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 28h 45m
FlixBus	26h 0m	1:00 PM	Chicago	Downtown Bus Station	3:00 PM	Biloxi, MS	Transit Center	Economy	$121	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/22/2026 1:00:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/23/2026 3:00:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 26h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 50m	10:30 PM	Chicago	Downtown Bus Station	10:20 PM	Biloxi, MS	Transit Center	Economy	$124	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/23/2026 10:30:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/24/2026 10:20:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 23h 50m
FlixBus	26h 0m	1:00 PM	Chicago	Downtown Bus Station	3:00 PM	Biloxi, MS	Transit Center	Economy	$124	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/23/2026 1:00:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/24/2026 3:00:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 26h 0m
Greyhound US	28h 45m	10:15 AM	Chicago	Canal & Van Buren	3:00 PM	Biloxi, MS	Transit Center	Economy	$125	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 4/23/2026 10:15:00 AM to Transit Center, Biloxi, MS (USA) arriving at 4/24/2026 3:00:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 28h 45m
FlixBus	25h 30m	1:30 PM	Chicago	95th Red Line Station	3:00 PM	Biloxi, MS	Transit Center	Economy	$125	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 4/23/2026 1:30:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/24/2026 3:00:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 25h 30m
Tornado Bus Company	35h 29m	1:30 PM	Chicago	California & 35th Street Bus Stop	12:59 AM	Biloxi, MS	Love's Travel Stop	Basic	$310	A Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 4/23/2026 1:30:00 PM to Love's Travel Stop, Biloxi, MS (USA) arriving at 4/25/2026 12:59:00 AM. 50 Basic ticket for $310 per person are available. Travel duration is 35h 29m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 45m	10:15 AM	Chicago	Union Station	3:00 PM	Biloxi, MS	Transit Center	Economy	$129	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 4/25/2026 10:15:00 AM to Transit Center, Biloxi, MS (USA) arriving at 4/26/2026 3:00:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 28h 45m
Greyhound US	23h 50m	10:30 PM	Chicago	Downtown Bus Station	10:20 PM	Biloxi, MS	Transit Center	Economy	$129	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/25/2026 10:30:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/26/2026 10:20:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 23h 50m
Greyhound US	28h 25m	11:10 PM	Chicago	Union Station	3:35 AM	Biloxi, MS	Transit Center	Economy	$136	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 4/25/2026 11:10:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/27/2026 3:35:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 28h 25m
FlixBus	26h 0m	1:00 PM	Chicago	Downtown Bus Station	3:00 PM	Biloxi, MS	Transit Center	Economy	$144	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/25/2026 1:00:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/26/2026 3:00:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 26h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 50m	11:45 PM	Chicago	95th Red Line Station	3:35 AM	Biloxi, MS	Transit Center	Economy	$118	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 4/26/2026 11:45:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/28/2026 3:35:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 27h 50m
FlixBus	25h 30m	1:30 PM	Chicago	95th Red Line Station	3:00 PM	Biloxi, MS	Transit Center	Economy	$119	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 4/26/2026 1:30:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/27/2026 3:00:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 25h 30m
FlixBus	26h 55m	7:25 PM	Chicago	95th Red Line Station	10:20 PM	Biloxi, MS	Transit Center	Economy	$119	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 4/26/2026 7:25:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/27/2026 10:20:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 26h 55m
Greyhound US	23h 50m	10:30 PM	Chicago	Downtown Bus Station	10:20 PM	Biloxi, MS	Transit Center	Economy	$122	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/26/2026 10:30:00 PM to Transit Center, Biloxi, MS (USA) arriving at 4/27/2026 10:20:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 23h 50m
Tornado Bus Company	35h 29m	1:30 PM	Chicago	California & 35th Street Bus Stop	12:59 AM	Biloxi, MS	Love's Travel Stop	Basic	$310	A Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 4/26/2026 1:30:00 PM to Love's Travel Stop, Biloxi, MS (USA) arriving at 4/28/2026 12:59:00 AM. 50 Basic ticket for $310 per person are available. Travel duration is 35h 29m

Best Price Offer: The price for the cheapest bus from Chicago to Biloxi, MS is $102 on 5/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Biloxi, MS

See here how frequent the connections between Chicago and Biloxi, MS are, during different times and days of the week.

Thursday is the busiest day, with more than 17 daily buses from Chicago to Biloxi, MS. Monday has instead the fewest connections, with only 5 daily coaches between Chicago and Biloxi, MS.

The busiest time of the day is the Evening, with 24 buses from Chicago to Biloxi, MS, while Morning sees the fewest connections between Chicago and Biloxi, MS, with 6 offers.

Facts about the bus from Chicago to Biloxi, MS

Compare all providers like Greyhound US, FlixBus and Tornado Bus Company that travel 8 times every day by bus from Chicago to Biloxi, MS in one click! Book your bus ticket from Chicago to Biloxi, MS starting from $102!

Cheapest Bus	$102
Fastest Bus	23h 50m
Earliest Bus	10:15 AM
Latest Bus	11:50 PM
Daily Bus Routes	8 Ø
Distance	796.5 miles
Bus Companies	Greyhound US, FlixBus and Tornado Bus Company

Cheapest bus connections from Chicago to Biloxi, MS

Every day, 8 buses from 3 bus companies leave Chicago for Biloxi, MS: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$114

Tuesday 04/21

Wednesday 04/22

$115

Thursday 04/23

$128

Friday 04/24

Saturday 04/25

$129

Sunday 04/26

$118

Monday 04/27

$119

Tuesday 04/28

$109

Wednesday 04/29

Thursday 04/30

Friday 05/01

$134

Saturday 05/02

$117

Sunday 05/03

$113

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$123

Saturday 05/09

Sunday 05/10

$117

Monday 05/11

Tuesday 05/12

$119

Wednesday 05/13

$120

Thursday 05/14

$102

Friday 05/15

Saturday 05/16

The cheapest time to travel from Chicago to Biloxi, MS

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Biloxi, MS, for the next 30 days.

With a price starting from $102, Thursday is the cheapest day for a bus from Chicago to Biloxi, MS. Wednesday instead is the most expensive day with prices starting from $115.

Morning is the cheapest day time for bus tickets from Chicago to Biloxi, MS, with $114. Evening is the most expensive time of the day with prices starting from $115.

How to save money travelling from Chicago to Biloxi, MS

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Biloxi, MS in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Biloxi, MS, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Biloxi, MS are also emptier.

All bus stations and stops in Chicago and Biloxi, MS

In the map below, you can see where to find all bus stations in Chicago and Biloxi, MS.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Transit Center

Dr Martin Luther King Jr Blvd 820

Love's Travel Stop

Cedar Lake Rd 11347

Point Cadet

Myrtle St

Service and Comfort on the bus from Chicago to Biloxi, MS

Want to know which seat classes are available on the buses from Chicago to Biloxi, MS? Or which bus companies serve the route Chicago to Biloxi, MS? Below you will find answers to your questions.

FAQs about the Chicago to Biloxi, MS bus

How much does a Chicago Biloxi, MS bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $102 and takes 28h 45m to reach Biloxi, MS. Compare offers to save money!

How much could I save by comparing buses from Chicago to Biloxi, MS?

This route is offered by 3 companies with a range of ticket prices between $102 and $310. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Biloxi, MS.

On average, how many connections are available from Chicago to Biloxi, MS each day?

Every day, the Chicago to Biloxi, MS bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Biloxi, MS take?

The fastest bus from Chicago to Biloxi, MS is offered by Greyhound US and takes 23h 50m. Bus tickets for this connection cost $115. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Biloxi, MS?

The earliest bus arriving in Biloxi, MS from Chicago starts at 10:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Biloxi, MS?

The latest bus trip departing from Chicago for Biloxi, MS starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Biloxi, MS route?

When traveling by bus from Chicago to Biloxi, MS, passengers can travel with Greyhound US, FlixBus and Tornado Bus Company. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Biloxi, MS?

You can check all the direct connections between Chicago and Biloxi, MS by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, FlixBus and Tornado Bus Company.

What can I take with me on the Chicago to Biloxi, MS bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Biloxi, MS bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Biloxi, MS bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Biloxi, MS on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to Biloxi, MS?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between Chicago and Biloxi, MS. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to Biloxi, MS?

Prices and availability for 8 trips between Chicago and Biloxi, MS change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to Biloxi, MS

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Biloxi, MS

Here’s an overview of the most popular bus routes to Chicago and to Biloxi, MS. Simply click on the connection of your choice, and you will find all the details about your bus route!