Bus Chicago to Harrisburg, PA - Compare all Companies

Compare all timetables for the bus from Chicago to Harrisburg, PA

Here is a selection of the cheapest bus trips from the schedule from Chicago to Harrisburg, PA from various bus operators like Greyhound US or FlixBus for the next days.

today

$134

tomorrow

Sunday

Monday

$137

Tuesday

Wednesday

Thursday

$118

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 20m	10:50 PM	Chicago	Downtown Bus Station	12:10 AM	Harrisburg, PA	Bus Station	Economy	$134	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/19/2025 10:50:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 12/21/2025 12:10:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 24h 20m
Greyhound US	22h 55m	11:10 PM	Chicago	Union Station	11:05 PM	Harrisburg, PA	Bus Station	Economy	$134	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/19/2025 11:10:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 12/20/2025 11:05:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 22h 55m
FlixBus	17h 0m	11:30 AM	Chicago	Downtown Bus Station	5:30 AM	Harrisburg, PA	Bus Station	Economy	$140	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/19/2025 11:30:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 12/20/2025 5:30:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 17h 0m
Greyhound US	15h 15m	6:00 PM	Chicago	Downtown Bus Station	10:15 AM	Harrisburg, PA	Bus Station	Economy	$150	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/19/2025 6:00:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 12/20/2025 10:15:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 15h 15m
FlixBus	15h 55m	7:15 PM	Chicago	Downtown Bus Station	12:10 PM	Harrisburg, PA	Bus Station	Economy	$248	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/19/2025 7:15:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 12/20/2025 12:10:00 PM. 50 Economy ticket for $248 per person are available. Travel duration is 15h 55m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 0m	11:30 AM	Chicago	Downtown Bus Station	5:30 AM	Harrisburg, PA	Bus Station	Economy	$137	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/22/2025 11:30:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 12/23/2025 5:30:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 17h 0m
FlixBus	20h 5m	8:25 AM	Chicago	95th Red Line Station	5:30 AM	Harrisburg, PA	Bus Station	Economy	$138	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/22/2025 8:25:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 12/23/2025 5:30:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 20h 5m
FlixBus	17h 25m	5:45 AM	Chicago	95th Red Line Station	12:10 AM	Harrisburg, PA	Bus Station	Economy	$140	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/22/2025 5:45:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 12/23/2025 12:10:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 17h 25m
Greyhound US	16h 15m	6:55 AM	Chicago	Downtown Bus Station	12:10 AM	Harrisburg, PA	Bus Station	Economy	$140	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/22/2025 6:55:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 12/23/2025 12:10:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 16h 15m
Greyhound US	15h 15m	6:00 PM	Chicago	Downtown Bus Station	10:15 AM	Harrisburg, PA	Bus Station	Economy	$143	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/22/2025 6:00:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 12/23/2025 10:15:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 15h 15m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 30m	7:40 PM	Chicago	95th Red Line Station	12:10 PM	Harrisburg, PA	Bus Station	Economy	$118	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/25/2025 7:40:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 12/26/2025 12:10:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 15h 30m
FlixBus	15h 55m	7:15 PM	Chicago	Downtown Bus Station	12:10 PM	Harrisburg, PA	Bus Station	Economy	$118	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/25/2025 7:15:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 12/26/2025 12:10:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 15h 55m
FlixBus	20h 5m	8:25 AM	Chicago	95th Red Line Station	5:30 AM	Harrisburg, PA	Bus Station	Economy	$119	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/25/2025 8:25:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 12/26/2025 5:30:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 20h 5m
Greyhound US	16h 15m	6:55 AM	Chicago	Downtown Bus Station	12:10 AM	Harrisburg, PA	Bus Station	Economy	$121	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/25/2025 6:55:00 AM to Bus Station, Harrisburg, PA (USA) arriving at 12/26/2025 12:10:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 16h 15m
Greyhound US	15h 15m	6:00 PM	Chicago	Downtown Bus Station	10:15 AM	Harrisburg, PA	Bus Station	Economy	$122	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/25/2025 6:00:00 PM to Bus Station, Harrisburg, PA (USA) arriving at 12/26/2025 10:15:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 15h 15m

Best Price Offer: The price for the cheapest bus from Chicago to Harrisburg, PA is $81 on 1/8/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Harrisburg, PA

See here how frequent the connections between Chicago and Harrisburg, PA are, during different times and days of the week.

Monday is the busiest day, with more than 24 daily buses from Chicago to Harrisburg, PA. Friday has instead the fewest connections, with only 5 daily coaches between Chicago and Harrisburg, PA.

The busiest time of the day is the Evening, with 28 buses from Chicago to Harrisburg, PA, while Afternoon sees the fewest connections between Chicago and Harrisburg, PA, with 4 offers.

Facts about the bus from Chicago to Harrisburg, PA

Compare all providers like Greyhound US and FlixBus that travel 17 times every day by bus from Chicago to Harrisburg, PA in one click! Book your bus ticket from Chicago to Harrisburg, PA starting from $81!

Cheapest Bus	$81
Fastest Bus	16h 15m
Earliest Bus	11:30 AM
Latest Bus	11:40 PM
Daily Bus Routes	17 Ø
Distance	573.8 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to Harrisburg, PA

Every day, 17 buses from 2 bus companies leave Chicago for Harrisburg, PA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$134

Saturday 12/20

Sunday 12/21

Monday 12/22

$137

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

$118

Friday 12/26

$133

Saturday 12/27

Sunday 12/28

$118

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

$81

Friday 01/09

Saturday 01/10

The cheapest time to travel from Chicago to Harrisburg, PA

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Harrisburg, PA, for the next 30 days.

With a price starting from $81, Thursday is the cheapest day for a bus from Chicago to Harrisburg, PA. Monday instead is the most expensive day with prices starting from $137.

Night is the cheapest day time for bus tickets from Chicago to Harrisburg, PA, with $81. Afternoon is the most expensive time of the day with prices starting from $121.

How to save money travelling from Chicago to Harrisburg, PA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Harrisburg, PA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Harrisburg, PA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Harrisburg, PA are also emptier.

All bus stations and stops in Chicago and Harrisburg, PA

In the map below, you can see where to find all bus stations in Chicago and Harrisburg, PA.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Bus Station

Market St 411

S 4th St & Chestnut St

N Cameron St

N Cameron St 2000

Old Country Buffet

Jonestown Rd 5083

Mall Parking Lot

Paxton St 3501

Service and Comfort on the bus from Chicago to Harrisburg, PA

Want to know which seat classes are available on the buses from Chicago to Harrisburg, PA? Or which bus companies serve the route Chicago to Harrisburg, PA? Below you will find answers to your questions.

FAQs about the Chicago to Harrisburg, PA bus

How much does a Chicago Harrisburg, PA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $81 and takes 16h 30m to reach Harrisburg, PA. Compare offers to save money!

How much could I save by comparing buses from Chicago to Harrisburg, PA?

This route is offered by 2 companies with a range of ticket prices between $81 and $248. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Harrisburg, PA.

On average, how many connections are available from Chicago to Harrisburg, PA each day?

Every day, the Chicago to Harrisburg, PA bus route is served by approximately 17 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Harrisburg, PA take?

The fastest bus from Chicago to Harrisburg, PA is offered by Greyhound US and takes 16h 15m. Bus tickets for this connection cost $150. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Harrisburg, PA?

The earliest bus arriving in Harrisburg, PA from Chicago starts at 11:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Harrisburg, PA?

The latest bus trip departing from Chicago for Harrisburg, PA starts at 11:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Harrisburg, PA route?

When traveling by bus from Chicago to Harrisburg, PA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Harrisburg, PA?

You can check all the direct connections between Chicago and Harrisburg, PA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Harrisburg, PA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Harrisburg, PA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Harrisburg, PA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Harrisburg, PA on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to Harrisburg, PA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 17 daily trips between Chicago and Harrisburg, PA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to Harrisburg, PA?

Prices and availability for 17 trips between Chicago and Harrisburg, PA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to Harrisburg, PA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Harrisburg, PA

Here’s an overview of the most popular bus routes to Chicago and to Harrisburg, PA. Simply click on the connection of your choice, and you will find all the details about your bus route!