Bus Frederick, MD to Myrtle Beach, SC

Compare all timetables for the bus from Frederick, MD to Myrtle Beach, SC

Here is a selection of the cheapest bus trips from the schedule from Frederick, MD to Myrtle Beach, SC from various bus operators like Greyhound US for the next days.

today

tomorrow

$108

Wednesday

Thursday

$118

Friday

Saturday

Sunday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	14h 45m	1:05 AM	Frederick, MD	Bus Stop	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$108	A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/20/2026 1:05:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/20/2026 3:50:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 14h 45m

Did you know that if you travel from Frederick, MD to Myrtle Beach, SC via Washington, DC, you can save more than $24? You can find the corresponding connections below.
- FlixBus
  
  14h 45m
  
  0
  
  1:05 AM
  
  Frederick, MD
  Bus Stop
  
  2:55 AM
  
  Washington, DC
  Union Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Bus Stop, Frederick, MD (USA) at 1/20/2026 1:05:00 AM to Union Station, Washington, DC (USA) arriving at 1/20/2026 2:55:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 50m
- FlixBus
  
  12h 10m
  
  0
  
  3:40 AM
  
  Washington, DC
  Union Station
  
  3:50 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $71
  
  A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 1/20/2026 3:40:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/20/2026 3:50:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 12h 10m
Travel time is the same as the direct connection, but you will save $24

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	14h 45m	1:05 AM	Frederick, MD	Bus Stop	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$118	A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/22/2026 1:05:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/22/2026 3:50:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 14h 45m

Did you know that if you travel from Frederick, MD to Myrtle Beach, SC via Washington, DC, you can save more than $34? You can find the corresponding connections below.
- FlixBus
  
  14h 45m
  
  0
  
  1:05 AM
  
  Frederick, MD
  Bus Stop
  
  2:55 AM
  
  Washington, DC
  Union Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Bus Stop, Frederick, MD (USA) at 1/20/2026 1:05:00 AM to Union Station, Washington, DC (USA) arriving at 1/20/2026 2:55:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 50m
- FlixBus
  
  12h 10m
  
  0
  
  3:40 AM
  
  Washington, DC
  Union Station
  
  3:50 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $71
  
  A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 1/20/2026 3:40:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/20/2026 3:50:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 12h 10m
Travel time is the same as the direct connection, but you will save $34

Best Price Offer: The price for the cheapest bus from Frederick, MD to Myrtle Beach, SC is $100 on 1/26/2026. Flexible travelers save on ticket prices.

Facts about the bus from Frederick, MD to Myrtle Beach, SC

Compare all providers like Greyhound US that travel 1 times every day by bus from Frederick, MD to Myrtle Beach, SC in one click! Book your bus ticket from Frederick, MD to Myrtle Beach, SC starting from $100!

Cheapest Bus	$100
Fastest Bus	14h 45m
Earliest Bus	1:05 AM
Latest Bus	1:05 AM
Daily Bus Routes	1 Ø
Distance	404.5 miles
Bus Companies	Greyhound US

Cheapest bus connections from Frederick, MD to Myrtle Beach, SC

Every day, 1 buses from 1 bus companies leave Frederick, MD for Myrtle Beach, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

Tuesday 01/20

$108

Wednesday 01/21

Thursday 01/22

$118

Friday 01/23

Saturday 01/24

Sunday 01/25

Monday 01/26

$100

Tuesday 01/27

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

How to save money travelling from Frederick, MD to Myrtle Beach, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Frederick, MD to Myrtle Beach, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Frederick, MD to Myrtle Beach, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Frederick, MD to Myrtle Beach, SC are also emptier.

All bus stations and stops in Frederick, MD and Myrtle Beach, SC

In the map below, you can see where to find all bus stations in Frederick, MD and Myrtle Beach, SC.

Bus Stop

Se St 100

Prospect Plaza - Dollar tree Bus Stop

Bus Stop

7th Ave N 511

Service and Comfort on the bus from Frederick, MD to Myrtle Beach, SC

Want to know which seat classes are available on the buses from Frederick, MD to Myrtle Beach, SC? Or which bus companies serve the route Frederick, MD to Myrtle Beach, SC? Below you will find answers to your questions.

FAQs about the Frederick, MD to Myrtle Beach, SC bus

How much does a Frederick, MD Myrtle Beach, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $100 and takes 14h 45m to reach Myrtle Beach, SC. Compare offers to save money!

How much could I save by comparing buses from Frederick, MD to Myrtle Beach, SC?

This route is offered by 1 companies with a range of ticket prices between $100 and $118. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Myrtle Beach, SC.

On average, how many connections are available from Frederick, MD to Myrtle Beach, SC each day?

Every day, the Frederick, MD to Myrtle Beach, SC bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Frederick, MD to Myrtle Beach, SC take?

The fastest bus from Frederick, MD to Myrtle Beach, SC is offered by Greyhound US and takes 14h 45m. Bus tickets for this connection cost $108. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Frederick, MD to Myrtle Beach, SC?

The earliest bus arriving in Myrtle Beach, SC from Frederick, MD starts at 1:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Frederick, MD to Myrtle Beach, SC?

The latest bus trip departing from Frederick, MD for Myrtle Beach, SC starts at 1:05 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Frederick, MD Myrtle Beach, SC route?

When traveling by bus from Frederick, MD to Myrtle Beach, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Frederick, MD and Myrtle Beach, SC?

You can check all the direct connections between Frederick, MD and Myrtle Beach, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Frederick, MD to Myrtle Beach, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Frederick, MD Myrtle Beach, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Frederick, MD Myrtle Beach, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Frederick, MD to Myrtle Beach, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Frederick, MD to Myrtle Beach, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Frederick, MD and Myrtle Beach, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Frederick, MD to Myrtle Beach, SC?

Prices and availability for 1 trips between Frederick, MD and Myrtle Beach, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Frederick, MD to Myrtle Beach, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Frederick, MD and to Myrtle Beach, SC

Here’s an overview of the most popular bus routes to Frederick, MD and to Myrtle Beach, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!