Which bus from Frederick, MD to Myrtle Beach, SC is the cheapest?

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Compare all timetables for the bus from Frederick, MD to Myrtle Beach, SC

Here is a selection of the cheapest bus trips from the schedule from Frederick, MD to Myrtle Beach, SC from various bus operators like Greyhound US for the next days.

today
tomorrow
$86
Tuesday
$84
Wednesday
$83
Thursday
$101
Friday
Saturday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 16h 15m 11:35 PM Frederick, MD Bus Stop 3:50 PM Myrtle Beach, SC Bus Stop  Economy $86
Greyhound US 18h 45m 5:05 AM Frederick, MD Bus Stop 11:50 PM Myrtle Beach, SC Bus Stop  Economy $87
  • Did you know that if you travel from Frederick, MD to Myrtle Beach, SC via Washington, DC, you can save more than $21? You can find the corresponding connections below.
    • Greyhound US
      18h 25m
      0
      5:25 AM
      Frederick, MD
      Bus Stop
      6:50 AM
      Washington, DC
      Union Station
      0
      Greyhound US
      Economy
      $8
      • Waiting Time 0h 25m
    • Greyhound US
      16h 35m
      0
      7:15 AM
      Washington, DC
      Union Station
      11:50 PM
      Myrtle Beach, SC
      Bus Stop
      0
      Greyhound US
      Economy
      $57
    Travel time is 2h 10m longer, but you will save $21

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 16h 15m 11:35 PM Frederick, MD Bus Stop 3:50 PM Myrtle Beach, SC Bus Stop  Economy $84
Greyhound US 18h 45m 5:05 AM Frederick, MD Bus Stop 11:50 PM Myrtle Beach, SC Bus Stop  Economy $85
  • Did you know that if you travel from Frederick, MD to Myrtle Beach, SC via Washington, DC, you can save more than $19? You can find the corresponding connections below.
    • Greyhound US
      18h 25m
      0
      5:25 AM
      Frederick, MD
      Bus Stop
      6:50 AM
      Washington, DC
      Union Station
      0
      Greyhound US
      Economy
      $8
      • Waiting Time 0h 25m
    • Greyhound US
      16h 35m
      0
      7:15 AM
      Washington, DC
      Union Station
      11:50 PM
      Myrtle Beach, SC
      Bus Stop
      0
      Greyhound US
      Economy
      $57
    Travel time is 2h 10m longer, but you will save $19

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 18h 45m 5:05 AM Frederick, MD Bus Stop 11:50 PM Myrtle Beach, SC Bus Stop  Economy $83
Greyhound US 16h 15m 11:35 PM Frederick, MD Bus Stop 3:50 PM Myrtle Beach, SC Bus Stop  Economy $84
  • Did you know that if you travel from Frederick, MD to Myrtle Beach, SC via Washington, DC, you can save more than $18? You can find the corresponding connections below.
    • Greyhound US
      18h 25m
      0
      5:25 AM
      Frederick, MD
      Bus Stop
      6:50 AM
      Washington, DC
      Union Station
      0
      Greyhound US
      Economy
      $8
      • Waiting Time 0h 25m
    • Greyhound US
      16h 35m
      0
      7:15 AM
      Washington, DC
      Union Station
      11:50 PM
      Myrtle Beach, SC
      Bus Stop
      0
      Greyhound US
      Economy
      $57
    Travel time is 2h 10m longer, but you will save $18

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 18h 45m 5:05 AM Frederick, MD Bus Stop 11:50 PM Myrtle Beach, SC Bus Stop  Economy $101
Greyhound US 16h 15m 11:35 PM Frederick, MD Bus Stop 3:50 PM Myrtle Beach, SC Bus Stop  Economy $105
  • Did you know that if you travel from Frederick, MD to Myrtle Beach, SC via Washington, DC, you can save more than $36? You can find the corresponding connections below.
    • Greyhound US
      18h 25m
      0
      5:25 AM
      Frederick, MD
      Bus Stop
      6:50 AM
      Washington, DC
      Union Station
      0
      Greyhound US
      Economy
      $8
      • Waiting Time 0h 25m
    • Greyhound US
      16h 35m
      0
      7:15 AM
      Washington, DC
      Union Station
      11:50 PM
      Myrtle Beach, SC
      Bus Stop
      0
      Greyhound US
      Economy
      $57
    Travel time is 2h 10m longer, but you will save $36

Best Price Offer: The price for the cheapest bus from Frederick, MD to Myrtle Beach, SC is $76 on 8/4/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Frederick, MD and Myrtle Beach, SC

See here how frequent the connections between Frederick, MD and Myrtle Beach, SC are, during different times and days of the week.
Thursday is the busiest day, with more than 4 daily buses from Frederick, MD to Myrtle Beach, SC. Monday has instead the fewest connections, with only 2 daily coaches between Frederick, MD and Myrtle Beach, SC.
The busiest time of the day is the Evening, with 5 buses from Frederick, MD to Myrtle Beach, SC, while Evening sees the fewest connections between Frederick, MD and Myrtle Beach, SC, with 5 offers.

Facts about the bus from Frederick, MD to Myrtle Beach, SC

Compare all providers like Greyhound US that travel 2 times every day by bus from Frederick, MD to Myrtle Beach, SC in one click! Book your bus ticket from Frederick, MD to Myrtle Beach, SC starting from $76!

Cheapest Bus $76
Fastest Bus 16h 15m
Earliest Bus 5:05 AM
Latest Bus 11:35 PM
Daily Bus Routes 2 Ø
Distance 404.5 miles
Bus Companies Greyhound US

Cheapest bus connections from Frederick, MD to Myrtle Beach, SC

Every day, 2 buses from 1 bus companies leave Frederick, MD for Myrtle Beach, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/19/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/19
Monday 07/20
$86
Tuesday 07/21
$84
Wednesday 07/22
$83
Thursday 07/23
$101
Friday 07/24
Saturday 07/25
Sunday 07/26
$108
Monday 07/27
$98
Tuesday 07/28
$94
Wednesday 07/29
$95
Thursday 07/30
$80
Friday 07/31
$92
Saturday 08/01
Sunday 08/02
$93
Monday 08/03
$85
Tuesday 08/04
$76
Wednesday 08/05
$86
Thursday 08/06
$88
Friday 08/07
$90
Saturday 08/08
$98
Sunday 08/09
$88
Monday 08/10
$85
Tuesday 08/11
Wednesday 08/12
Thursday 08/13
$89
Friday 08/14
$81
Saturday 08/15

The cheapest time to travel from Frederick, MD to Myrtle Beach, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Frederick, MD to Myrtle Beach, SC, for the next 30 days.
With a price starting from $76, Tuesday is the cheapest day for a bus from Frederick, MD to Myrtle Beach, SC. Monday instead is the most expensive day with prices starting from $85.
Night is the cheapest day time for bus tickets from Frederick, MD to Myrtle Beach, SC, with $76. Evening is the most expensive time of the day with prices starting from $84.

How to save money travelling from Frederick, MD to Myrtle Beach, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Frederick, MD to Myrtle Beach, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Frederick, MD to Myrtle Beach, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Frederick, MD to Myrtle Beach, SC are also emptier.

Beloved bus companies from Frederick, MD to Myrtle Beach, SC

These are the most booked bus companies between Frederick, MD to Myrtle Beach, SC from our users.

Greyhound US from Frederick, MD to Myrtle Beach, SC

Greyhound US

Here you will find the key facts about the Greyhound US bus route Frederick, MD to Myrtle Beach, SC:

Cheapest Price $83
Fastest Bus 16h 15m
Earliest Bus 5:05 AM
Last Bus 11:35 PM
Daily Connections 2 Ø
Found on 6/23/2026

All bus stations and stops in Frederick, MD and Myrtle Beach, SC

In the map below, you can see where to find all bus stations in Frederick, MD and Myrtle Beach, SC.

Service and Comfort on the bus from Frederick, MD to Myrtle Beach, SC

Want to know which seat classes are available on the buses from Frederick, MD to Myrtle Beach, SC? Or which bus companies serve the route Frederick, MD to Myrtle Beach, SC? Below you will find answers to your questions.

FAQs about the Frederick, MD to Myrtle Beach, SC bus

How much does a Frederick, MD Myrtle Beach, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $76 and takes 18h 45m to reach Myrtle Beach, SC. Compare offers to save money!

How much could I save by comparing buses from Frederick, MD to Myrtle Beach, SC?

This route is offered by 1 companies with a range of ticket prices between $76 and $115. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Myrtle Beach, SC.

On average, how many connections are available from Frederick, MD to Myrtle Beach, SC each day?

Every day, the Frederick, MD to Myrtle Beach, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Frederick, MD to Myrtle Beach, SC take?

The fastest bus from Frederick, MD to Myrtle Beach, SC is offered by Greyhound US and takes 16h 15m. Bus tickets for this connection cost $86. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Frederick, MD to Myrtle Beach, SC?

The earliest bus arriving in Myrtle Beach, SC from Frederick, MD starts at 5:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Frederick, MD to Myrtle Beach, SC?

The latest bus trip departing from Frederick, MD for Myrtle Beach, SC starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Frederick, MD Myrtle Beach, SC route?

When traveling by bus from Frederick, MD to Myrtle Beach, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Frederick, MD and Myrtle Beach, SC?

You can check all the direct connections between Frederick, MD and Myrtle Beach, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Frederick, MD to Myrtle Beach, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Frederick, MD Myrtle Beach, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Frederick, MD Myrtle Beach, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Frederick, MD to Myrtle Beach, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Frederick, MD to Myrtle Beach, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Frederick, MD and Myrtle Beach, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Frederick, MD to Myrtle Beach, SC?

Prices and availability for 2 trips between Frederick, MD and Myrtle Beach, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Frederick, MD to Myrtle Beach, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Frederick, MD and to Myrtle Beach, SC

Here’s an overview of the most popular bus routes to Frederick, MD and to Myrtle Beach, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus Camden, SC to Myrtle Beach, SC Bus Camden, SC to Myrtle Beach, SC
Buses to Myrtle Beach, SC from Ashland, KY Buses to Myrtle Beach, SC from Ashland, KY
From Edgewood, MD to Myrtle Beach, SC bus From Edgewood, MD to Myrtle Beach, SC bus
From Columbus, OH to Myrtle Beach, SC bus From Columbus, OH to Myrtle Beach, SC bus
Popular Airport Shuttles to Frederick, MD and to Myrtle Beach, SC
CheckMyBus › Buses in USA › Bus to Frederick, MD › Bus to Myrtle Beach, SC

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