Bus Harrisburg, PA to Buffalo, NY: Compare prices and save money

Compare all timetables for the bus from Harrisburg, PA to Buffalo, NY

Here is a selection of the cheapest bus trips from the schedule from Harrisburg, PA to Buffalo, NY from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

$80

Wednesday

Thursday

$83

Friday

$83

Saturday

Sunday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 20m	12:45 AM	Harrisburg, PA	Bus Station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$80	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/21/2026 12:45:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 4/21/2026 3:05:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 20m
Greyhound US	14h 15m	2:30 AM	Harrisburg, PA	Bus Station	4:45 PM	Buffalo, NY	Central Bus Station	Economy	$80	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/21/2026 2:30:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 4/21/2026 4:45:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 15m
Greyhound US	13h 10m	5:40 AM	Harrisburg, PA	Bus Station	6:50 PM	Buffalo, NY	Central Bus Station	Economy	$80	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/21/2026 5:40:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 4/21/2026 6:50:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 13h 10m
FlixBus	18h 5m	12:15 PM	Harrisburg, PA	Bus Station	6:20 AM	Buffalo, NY	Central Bus Station	Economy	$80	A Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 4/21/2026 12:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 4/22/2026 6:20:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 18h 5m
FlixBus	14h 45m	5:30 PM	Harrisburg, PA	Bus Station	8:15 AM	Buffalo, NY	Central Bus Station	Economy	$81	A Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 4/21/2026 5:30:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 4/22/2026 8:15:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 15m	2:30 AM	Harrisburg, PA	Bus Station	4:45 PM	Buffalo, NY	Central Bus Station	Economy	$83	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/23/2026 2:30:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 4/23/2026 4:45:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 14h 15m
Greyhound US	13h 10m	9:10 PM	Harrisburg, PA	Bus Station	10:20 AM	Buffalo, NY	Central Bus Station	Economy	$83	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/23/2026 9:10:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 4/24/2026 10:20:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 13h 10m
Greyhound US	15h 45m	11:20 PM	Harrisburg, PA	Bus Station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$83	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/23/2026 11:20:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 4/24/2026 3:05:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 45m
Greyhound US	14h 20m	12:45 AM	Harrisburg, PA	Bus Station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$84	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/23/2026 12:45:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 4/23/2026 3:05:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 14h 20m
Greyhound US	14h 30m	2:30 PM	Harrisburg, PA	Bus Station	5:00 AM	Buffalo, NY	Central Bus Station	Economy	$84	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/23/2026 2:30:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 4/24/2026 5:00:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 14h 30m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 45m	11:20 PM	Harrisburg, PA	Bus Station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$83	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/24/2026 11:20:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 4/25/2026 3:05:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 45m
Greyhound US	14h 20m	12:45 AM	Harrisburg, PA	Bus Station	3:05 PM	Buffalo, NY	Central Bus Station	Economy	$84	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/24/2026 12:45:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 4/24/2026 3:05:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 14h 20m
Greyhound US	14h 15m	2:30 AM	Harrisburg, PA	Bus Station	4:45 PM	Buffalo, NY	Central Bus Station	Economy	$84	A Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 4/24/2026 2:30:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 4/24/2026 4:45:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 14h 15m
FlixBus	14h 45m	5:30 PM	Harrisburg, PA	Bus Station	8:15 AM	Buffalo, NY	Central Bus Station	Economy	$89	A Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 4/24/2026 5:30:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 4/25/2026 8:15:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 14h 45m

Best Price Offer: The price for the cheapest bus from Harrisburg, PA to Buffalo, NY is $71 on 5/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Harrisburg, PA and Buffalo, NY

See here how frequent the connections between Harrisburg, PA and Buffalo, NY are, during different times and days of the week.

Tuesday is the busiest day, with more than 7 daily buses from Harrisburg, PA to Buffalo, NY. Thursday has instead the fewest connections, with only 6 daily coaches between Harrisburg, PA and Buffalo, NY.

The busiest time of the day is the Night, with 9 buses from Harrisburg, PA to Buffalo, NY, while Afternoon sees the fewest connections between Harrisburg, PA and Buffalo, NY, with 5 offers.

Facts about the bus from Harrisburg, PA to Buffalo, NY

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Harrisburg, PA to Buffalo, NY in one click! Book your bus ticket from Harrisburg, PA to Buffalo, NY starting from $71!

Cheapest Bus	$71
Fastest Bus	13h 10m
Earliest Bus	12:45 AM
Latest Bus	11:20 PM
Daily Bus Routes	6 Ø
Distance	210.2 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Harrisburg, PA to Buffalo, NY

Every day, 6 buses from 2 bus companies leave Harrisburg, PA for Buffalo, NY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$129

Tuesday 04/21

$80

Wednesday 04/22

Thursday 04/23

$83

Friday 04/24

$83

Saturday 04/25

Sunday 04/26

Monday 04/27

Tuesday 04/28

Wednesday 04/29

$84

Thursday 04/30

Friday 05/01

$138

Saturday 05/02

$78

Sunday 05/03

Monday 05/04

$71

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$77

Saturday 05/09

$77

Sunday 05/10

$81

Monday 05/11

Tuesday 05/12

$73

Wednesday 05/13

Thursday 05/14

Friday 05/15

$84

Saturday 05/16

The cheapest time to travel from Harrisburg, PA to Buffalo, NY

See here on which day and which time of the day you can find the cheapest bus ticket from Harrisburg, PA to Buffalo, NY, for the next 30 days.

With a price starting from $73, Tuesday is the cheapest day for a bus from Harrisburg, PA to Buffalo, NY. Thursday instead is the most expensive day with prices starting from $83.

Night is the cheapest day time for bus tickets from Harrisburg, PA to Buffalo, NY, with $71. Afternoon is the most expensive time of the day with prices starting from $80.

How to save money travelling from Harrisburg, PA to Buffalo, NY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Harrisburg, PA to Buffalo, NY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Harrisburg, PA to Buffalo, NY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Harrisburg, PA to Buffalo, NY are also emptier.

All bus stations and stops in Harrisburg, PA and Buffalo, NY

In the map below, you can see where to find all bus stations in Harrisburg, PA and Buffalo, NY.

S 4th St & Chestnut St

N Cameron St

N Cameron St 2000

Mall Parking Lot

Paxton St 3501

Old Country Buffet

Jonestown Rd 5083

Bus Station

Market St 411

Central Bus Station

Ellicott Street 181

MTC / Downtown Terminal

Ellicott Street 181

Maple Road Gulf

Maple Rd 4641

Asia Food Market

Niagara Falls Blvd 2055

Cleveland Hall

Service and Comfort on the bus from Harrisburg, PA to Buffalo, NY

Want to know which seat classes are available on the buses from Harrisburg, PA to Buffalo, NY? Or which bus companies serve the route Harrisburg, PA to Buffalo, NY? Below you will find answers to your questions.

FAQs about the Harrisburg, PA to Buffalo, NY bus

How much does a Harrisburg, PA Buffalo, NY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $71 and takes 13h 10m to reach Buffalo, NY. Compare offers to save money!

How much could I save by comparing buses from Harrisburg, PA to Buffalo, NY?

This route is offered by 2 companies with a range of ticket prices between $71 and $89. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Buffalo, NY.

On average, how many connections are available from Harrisburg, PA to Buffalo, NY each day?

Every day, the Harrisburg, PA to Buffalo, NY bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Harrisburg, PA to Buffalo, NY take?

The fastest bus from Harrisburg, PA to Buffalo, NY is offered by Greyhound US and takes 13h 10m. Bus tickets for this connection cost $80. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Harrisburg, PA to Buffalo, NY?

The earliest bus arriving in Buffalo, NY from Harrisburg, PA starts at 12:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Harrisburg, PA to Buffalo, NY?

The latest bus trip departing from Harrisburg, PA for Buffalo, NY starts at 11:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Harrisburg, PA Buffalo, NY route?

When traveling by bus from Harrisburg, PA to Buffalo, NY, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Harrisburg, PA and Buffalo, NY?

You can check all the direct connections between Harrisburg, PA and Buffalo, NY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Harrisburg, PA to Buffalo, NY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Harrisburg, PA Buffalo, NY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Harrisburg, PA Buffalo, NY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Harrisburg, PA to Buffalo, NY on your planned travel date.

How does CheckMyBus find the best bus deals from Harrisburg, PA to Buffalo, NY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Harrisburg, PA and Buffalo, NY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Harrisburg, PA to Buffalo, NY?

Prices and availability for 6 trips between Harrisburg, PA and Buffalo, NY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Harrisburg, PA to Buffalo, NY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Harrisburg, PA and to Buffalo, NY

Here’s an overview of the most popular bus routes to Harrisburg, PA and to Buffalo, NY. Simply click on the connection of your choice, and you will find all the details about your bus route!