Bus Houston to Santiago de Queretaro

Compare all timetables for the bus from Houston to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from Houston to Santiago de Queretaro from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today

$214

tomorrow

$222

Saturday

$226

Sunday

$172

Monday

$196

Tuesday

$197

Wednesday

$173

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 10m	2:30 PM	Houston	Harrisburg Blvd Station	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$214	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/18/2025 2:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 6:40:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 28h 10m
Greyhound US	26h 35m	5:25 PM	Houston	Harrisburg Blvd Station	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$224	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/18/2025 5:25:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 8:00:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 26h 35m
FlixBus	29h 35m	2:25 PM	Houston	Downtown Houston	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$230	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/18/2025 2:25:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 8:00:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 29h 35m
FlixBus	29h 20m	2:40 PM	Houston	Uptown/Upper Kirby	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$230	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/18/2025 2:40:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 8:00:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 29h 20m
Greyhound Lines Mexico	24h 30m	9:00 AM	Houston	Harrisburg Blvd Station	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$240	A Bus from Greyhound Lines Mexico goes from Harrisburg Blvd Station, Houston (USA) at 12/18/2025 9:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/19/2025 9:30:00 AM. 50 Economy ticket for $240 per person are available. Travel duration is 24h 30m

Did you know that if you travel from Houston to Santiago de Queretaro via Reynosa, you can save more than $56? You can find the corresponding connections below.
- Busbud
  
  23h 53m
  
  0
  
  9:30 AM
  
  Houston
  SW Agencia Autobuses
  
  6:05 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $64
  
  A Bus from Busbud goes from SW Agencia Autobuses, Houston (USA) at 12/19/2025 9:30:00 AM to Hotel City Express, Reynosa (Mexico) arriving at 12/19/2025 6:05:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 8h 35m
- Busbud
  
  12h 53m
  
  0
  
  8:30 PM
  
  Reynosa
  Central Bus Station
  
  9:23 AM
  
  Santiago de Queretaro
  Bus Station
  
  0
  
  Economy
  
  $94
  
  A Bus from Busbud goes from Central Bus Station, Reynosa (Mexico) at 12/19/2025 8:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/20/2025 9:23:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 12h 53m
Travel Time is 0h 37m shorter, and you will save $56

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 25m	7:35 PM	Houston	Downtown Houston	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$222	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/19/2025 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 8:00:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 24h 25m
FlixBus	24h 10m	7:50 PM	Houston	Uptown/Upper Kirby	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$222	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/19/2025 7:50:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 8:00:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 24h 10m
Greyhound Lines Mexico	24h 0m	9:30 AM	Houston	SW Agencia Autobuses	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$233	A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/19/2025 9:30:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 9:30:00 AM. 50 Economy ticket for $233 per person are available. Travel duration is 24h 0m
Greyhound Lines Mexico	30h 45m	11:55 AM	Houston	Harrisburg Blvd Station	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$244	A Bus from Greyhound Lines Mexico goes from Harrisburg Blvd Station, Houston (USA) at 12/19/2025 11:55:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 6:40:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 30h 45m
FlixBus	26h 30m	7:00 AM	Houston	Downtown Houston	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$259	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/19/2025 7:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/20/2025 9:30:00 AM. 50 Economy ticket for $259 per person are available. Travel duration is 26h 30m

Did you know that if you travel from Houston to Santiago de Queretaro via Reynosa, you can save more than $64? You can find the corresponding connections below.
- Busbud
  
  23h 53m
  
  0
  
  9:30 AM
  
  Houston
  SW Agencia Autobuses
  
  6:05 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $64
  
  A Bus from Busbud goes from SW Agencia Autobuses, Houston (USA) at 12/19/2025 9:30:00 AM to Hotel City Express, Reynosa (Mexico) arriving at 12/19/2025 6:05:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 8h 35m
- Busbud
  
  12h 53m
  
  0
  
  8:30 PM
  
  Reynosa
  Central Bus Station
  
  9:23 AM
  
  Santiago de Queretaro
  Bus Station
  
  0
  
  Economy
  
  $94
  
  A Bus from Busbud goes from Central Bus Station, Reynosa (Mexico) at 12/19/2025 8:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/20/2025 9:23:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 12h 53m
Travel Time is 0h 7m shorter, and you will save $64

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 25m	7:35 PM	Houston	Downtown Houston	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$226	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/20/2025 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/21/2025 8:00:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 24h 25m
FlixBus	24h 10m	7:50 PM	Houston	Uptown/Upper Kirby	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$226	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/20/2025 7:50:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/21/2025 8:00:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 24h 10m
Greyhound US	28h 10m	2:30 PM	Houston	Harrisburg Blvd Station	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$226	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/20/2025 2:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 28h 10m
Greyhound US	26h 35m	5:25 PM	Houston	Harrisburg Blvd Station	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$226	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/20/2025 5:25:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/21/2025 8:00:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 26h 35m
Greyhound Lines Mexico	30h 45m	11:55 AM	Houston	Harrisburg Blvd Station	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$248	A Bus from Greyhound Lines Mexico goes from Harrisburg Blvd Station, Houston (USA) at 12/20/2025 11:55:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $248 per person are available. Travel duration is 30h 45m

Did you know that if you travel from Houston to Santiago de Queretaro via Reynosa, you can save more than $89? You can find the corresponding connections below.
- Busbud
  
  31h 30m
  
  0
  
  2:00 AM
  
  Houston
  Harrisburg Blvd Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $60
  
  A Bus from Busbud goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 2:00:00 AM to Hotel City Express, Reynosa (Mexico) arriving at 12/22/2025 5:00:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 15h 0m
- FlixBus
  
  15h 20m
  
  0
  
  6:10 PM
  
  Reynosa
  Central Bus Station
  
  9:30 AM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $77
  
  A Bus from FlixBus goes from Central Bus Station, Reynosa (Mexico) at 12/22/2025 6:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/23/2025 9:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 20m
Travel time is 7h 20m longer, but you will save $89

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 10m	2:30 PM	Houston	Harrisburg Blvd Station	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$172	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/21/2025 2:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/22/2025 6:40:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 28h 10m
FlixBus	28h 30m	2:10 PM	Houston	Uptown/Upper Kirby	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$174	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/21/2025 2:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/22/2025 6:40:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 28h 30m
FlixBus	28h 45m	1:55 PM	Houston	Downtown Houston	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$175	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/21/2025 1:55:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/22/2025 6:40:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 28h 45m
Greyhound Lines Mexico	24h 0m	9:30 AM	Houston	SW Agencia Autobuses	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$194	A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/21/2025 9:30:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/22/2025 9:30:00 AM. 50 Economy ticket for $194 per person are available. Travel duration is 24h 0m
Greyhound Lines Mexico	24h 30m	9:00 AM	Houston	Harrisburg Blvd Station	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$197	A Bus from Greyhound Lines Mexico goes from Harrisburg Blvd Station, Houston (USA) at 12/21/2025 9:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/22/2025 9:30:00 AM. 50 Economy ticket for $197 per person are available. Travel duration is 24h 30m

Did you know that if you travel from Houston to Santiago de Queretaro via Reynosa, you can save more than $35? You can find the corresponding connections below.
- Busbud
  
  31h 30m
  
  0
  
  2:00 AM
  
  Houston
  Harrisburg Blvd Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $60
  
  A Bus from Busbud goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 2:00:00 AM to Hotel City Express, Reynosa (Mexico) arriving at 12/22/2025 5:00:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 15h 0m
- FlixBus
  
  15h 20m
  
  0
  
  6:10 PM
  
  Reynosa
  Central Bus Station
  
  9:30 AM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $77
  
  A Bus from FlixBus goes from Central Bus Station, Reynosa (Mexico) at 12/22/2025 6:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/23/2025 9:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 20m
Travel time is 7h 30m longer, but you will save $35

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 10m	2:30 PM	Houston	Harrisburg Blvd Station	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$196	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 2:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/23/2025 6:40:00 PM. 50 Economy ticket for $196 per person are available. Travel duration is 28h 10m
FlixBus	26h 45m	11:35 PM	Houston	Harrisburg Blvd Station	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$199	A Bus from FlixBus goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 11:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/24/2025 2:20:00 AM. 50 Economy ticket for $199 per person are available. Travel duration is 26h 45m
FlixBus	28h 30m	2:10 PM	Houston	Uptown/Upper Kirby	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$200	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/22/2025 2:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/23/2025 6:40:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 28h 30m
Greyhound US	24h 20m	2:00 AM	Houston	Harrisburg Blvd Station	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$223	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 2:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/23/2025 2:20:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 24h 20m
Greyhound Lines Mexico	24h 30m	9:00 AM	Houston	Harrisburg Blvd Station	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$242	A Bus from Greyhound Lines Mexico goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 9:00:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/23/2025 9:30:00 AM. 50 Economy ticket for $242 per person are available. Travel duration is 24h 30m

Did you know that if you travel from Houston to Santiago de Queretaro via Reynosa, you can save more than $59? You can find the corresponding connections below.
- Busbud
  
  31h 30m
  
  0
  
  2:00 AM
  
  Houston
  Harrisburg Blvd Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $60
  
  A Bus from Busbud goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 2:00:00 AM to Hotel City Express, Reynosa (Mexico) arriving at 12/22/2025 5:00:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 15h 0m
- FlixBus
  
  15h 20m
  
  0
  
  6:10 PM
  
  Reynosa
  Central Bus Station
  
  9:30 AM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $77
  
  A Bus from FlixBus goes from Central Bus Station, Reynosa (Mexico) at 12/22/2025 6:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/23/2025 9:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 20m
Travel time is 7h 10m longer, but you will save $59

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	26h 15m	12:05 AM	Houston	SW Agencia Autobuses	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$197	A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/23/2025 12:05:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/24/2025 2:20:00 AM. 50 Economy ticket for $197 per person are available. Travel duration is 26h 15m
FlixBus	34h 5m	11:35 PM	Houston	Harrisburg Blvd Station	9:40 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$198	A Bus from FlixBus goes from Harrisburg Blvd Station, Houston (USA) at 12/23/2025 11:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/25/2025 9:40:00 AM. 50 Economy ticket for $198 per person are available. Travel duration is 34h 5m
FlixBus	24h 25m	7:35 PM	Houston	Downtown Houston	8:00 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$206	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/23/2025 7:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/24/2025 8:00:00 PM. 50 Economy ticket for $206 per person are available. Travel duration is 24h 25m
Greyhound US	28h 10m	2:30 PM	Houston	Harrisburg Blvd Station	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$216	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/23/2025 2:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/24/2025 6:40:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 28h 10m
Greyhound US	31h 25m	6:55 PM	Houston	Harrisburg Blvd Station	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$230	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/23/2025 6:55:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/25/2025 2:20:00 AM. 50 Economy ticket for $230 per person are available. Travel duration is 31h 25m

Did you know that if you travel from Houston to Santiago de Queretaro via Reynosa, you can save more than $60? You can find the corresponding connections below.
- Busbud
  
  31h 30m
  
  0
  
  2:00 AM
  
  Houston
  Harrisburg Blvd Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $60
  
  A Bus from Busbud goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 2:00:00 AM to Hotel City Express, Reynosa (Mexico) arriving at 12/22/2025 5:00:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 15h 0m
- FlixBus
  
  15h 20m
  
  0
  
  6:10 PM
  
  Reynosa
  Central Bus Station
  
  9:30 AM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $77
  
  A Bus from FlixBus goes from Central Bus Station, Reynosa (Mexico) at 12/22/2025 6:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/23/2025 9:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 20m
Travel time is 7h 5m longer, but you will save $60

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 10m	2:30 PM	Houston	Harrisburg Blvd Station	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$173	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/24/2025 2:30:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/25/2025 6:40:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 28h 10m
FlixBus	31h 15m	11:25 AM	Houston	Uptown/Upper Kirby	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$176	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/24/2025 11:25:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/25/2025 6:40:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 31h 15m
FlixBus	31h 30m	11:10 AM	Houston	Downtown Houston	6:40 PM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$179	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/24/2025 11:10:00 AM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/25/2025 6:40:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 31h 30m
FlixBus	33h 55m	11:35 PM	Houston	Harrisburg Blvd Station	9:30 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$190	A Bus from FlixBus goes from Harrisburg Blvd Station, Houston (USA) at 12/24/2025 11:35:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/26/2025 9:30:00 AM. 50 Economy ticket for $190 per person are available. Travel duration is 33h 55m
Greyhound US	31h 25m	6:55 PM	Houston	Harrisburg Blvd Station	2:20 AM	Santiago de Queretaro	Centro Comercial Galeria	Economy	$201	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/24/2025 6:55:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/26/2025 2:20:00 AM. 50 Economy ticket for $201 per person are available. Travel duration is 31h 25m

Did you know that if you travel from Houston to Santiago de Queretaro via Reynosa, you can save more than $46? You can find the corresponding connections below.
- Busbud
  
  31h 30m
  
  0
  
  2:00 AM
  
  Houston
  Harrisburg Blvd Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $52
  
  A Bus from Busbud goes from Harrisburg Blvd Station, Houston (USA) at 12/25/2025 2:00:00 AM to Hotel City Express, Reynosa (Mexico) arriving at 12/25/2025 5:00:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 15h 0m
- Busbud
  
  15h 20m
  
  0
  
  6:10 PM
  
  Reynosa
  Hotel City Express
  
  9:30 AM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $75
  
  A Bus from Busbud goes from Hotel City Express, Reynosa (Mexico) at 12/25/2025 6:10:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 12/26/2025 9:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 15h 20m
Travel time is 3h 20m longer, but you will save $46

Best Price Offer: The price for the cheapest bus from Houston to Santiago de Queretaro is $98 on 1/7/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Houston and Santiago de Queretaro

See here how frequent the connections between Houston and Santiago de Queretaro are, during different times and days of the week.

Sunday is the busiest day, with more than 24 daily buses from Houston to Santiago de Queretaro. Wednesday has instead the fewest connections, with only 13 daily coaches between Houston and Santiago de Queretaro.

The busiest time of the day is the Morning, with 42 buses from Houston to Santiago de Queretaro, while Night sees the fewest connections between Houston and Santiago de Queretaro, with 11 offers.

Facts about the bus from Houston to Santiago de Queretaro

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 18 times every day by bus from Houston to Santiago de Queretaro in one click! Book your bus ticket from Houston to Santiago de Queretaro starting from $98!

Cheapest Bus	$98
Fastest Bus	24h 0m
Earliest Bus	9:00 AM
Latest Bus	11:35 PM
Daily Bus Routes	18 Ø
Distance	706.2 miles
Bus Companies	FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from Houston to Santiago de Queretaro

Every day, 18 buses from 3 bus companies leave Houston for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$214

Friday 12/19

$224

Saturday 12/20

$248

Sunday 12/21

$172

Monday 12/22

$196

Tuesday 12/23

$193

Wednesday 12/24

$173

Thursday 12/25

$163

Friday 12/26

$196

Saturday 12/27

$189

Sunday 12/28

$147

Monday 12/29

$178

Tuesday 12/30

$167

Wednesday 12/31

$116

Thursday 01/01

$177

Friday 01/02

$172

Saturday 01/03

$177

Sunday 01/04

$163

Monday 01/05

$148

Tuesday 01/06

$124

Wednesday 01/07

$98

Thursday 01/08

$103

Friday 01/09

$142

Saturday 01/10

The cheapest time to travel from Houston to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to Santiago de Queretaro, for the next 30 days.

With a price starting from $94, Tuesday is the cheapest day for a bus from Houston to Santiago de Queretaro. Saturday instead is the most expensive day with prices starting from $153.

Night is the cheapest day time for bus tickets from Houston to Santiago de Queretaro, with $94. Evening is the most expensive time of the day with prices starting from $190.

How to save money travelling from Houston to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Santiago de Queretaro are also emptier.

Beloved bus companies from Houston to Santiago de Queretaro

These are the most booked bus companies between Houston to Santiago de Queretaro from our users.

FlixBus from Houston to Santiago de Queretaro

Here you will find the key facts about the FlixBus bus route Houston to Santiago de Queretaro:

Cheapest Price	$174
Fastest Bus	24h 10m
Earliest Bus	1:55 PM
Last Bus	11:35 PM
Daily Connections	10 Ø
Found on	12/18/2025

All bus stations and stops in Houston and Santiago de Queretaro

In the map below, you can see where to find all bus stations in Houston and Santiago de Queretaro.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Uptown/Upper Kirby

Southwest Fwy 2525

Chase Bank

Milam Street 212

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Houston to Santiago de Queretaro? Compare all modes of transports from Houston to Santiago de Queretaro.

Service and Comfort on the bus from Houston to Santiago de Queretaro

Want to know which seat classes are available on the buses from Houston to Santiago de Queretaro? Or which bus companies serve the route Houston to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the Houston to Santiago de Queretaro bus

How much does a Houston Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $98 and takes 28h 10m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from Houston to Santiago de Queretaro?

This route is offered by 3 companies with a range of ticket prices between $98 and $278. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from Houston to Santiago de Queretaro each day?

Every day, the Houston to Santiago de Queretaro bus route is served by approximately 18 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to Santiago de Queretaro take?

The fastest bus from Houston to Santiago de Queretaro is offered by Greyhound Lines Mexico and takes 24h 0m. Bus tickets for this connection cost $245. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from Houston starts at 9:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to Santiago de Queretaro?

The latest bus trip departing from Houston for Santiago de Queretaro starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston Santiago de Queretaro route?

When traveling by bus from Houston to Santiago de Queretaro, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and Santiago de Queretaro?

You can check all the direct connections between Houston and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Santiago de Queretaro on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to Santiago de Queretaro?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 18 daily trips between Houston and Santiago de Queretaro. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to Santiago de Queretaro?

Prices and availability for 18 trips between Houston and Santiago de Queretaro change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to Santiago de Queretaro

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to Houston and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!