Bus Indianapolis to Roanoke, VA - Compare all Companies

Compare all timetables for the bus from Indianapolis to Roanoke, VA

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to Roanoke, VA from various bus operators like Greyhound US for the next days.

today

tomorrow

$122

Monday

Tuesday

$155

Wednesday

$150

Thursday

Friday

$114

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	16h 25m	11:25 AM	Indianapolis	Central Bus Station	3:50 AM	Roanoke, VA	Greyhound		Economy	$122	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 2/8/2026 11:25:00 AM to Greyhound, Roanoke, VA (USA) arriving at 2/9/2026 3:50:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 16h 25m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	16h 25m	11:25 AM	Indianapolis	Central Bus Station	3:50 AM	Roanoke, VA	Greyhound		Economy	$155	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 2/10/2026 11:25:00 AM to Greyhound, Roanoke, VA (USA) arriving at 2/11/2026 3:50:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 16h 25m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	16h 25m	11:25 AM	Indianapolis	Central Bus Station	3:50 AM	Roanoke, VA	Greyhound		Economy	$150	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 2/11/2026 11:25:00 AM to Greyhound, Roanoke, VA (USA) arriving at 2/12/2026 3:50:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 16h 25m

Did you know that if you travel from Indianapolis to Roanoke, VA via Knoxville, TN, you can save more than $23? You can find the corresponding connections below.
- FlixBus
  
  16h 25m
  
  0
  
  11:25 AM
  
  Indianapolis
  Central Bus Station
  
  10:40 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  0
  
  Economy
  
  $79
  
  A Bus from FlixBus goes from Central Bus Station, Indianapolis (USA) at 2/13/2026 11:25:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 2/13/2026 10:40:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 11h 15m
- FlixBus
  
  5h 0m
  
  0
  
  10:50 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  3:50 AM
  
  Roanoke, VA
  Greyhound
  
  0
  
  Economy
  
  $48
  
  A Bus from FlixBus goes from Greyhound Bus Station, Knoxville, TN (USA) at 2/13/2026 10:50:00 PM to Greyhound, Roanoke, VA (USA) arriving at 2/14/2026 3:50:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 0m
Travel time is the same as the direct connection, but you will save $23

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	16h 25m	11:25 AM	Indianapolis	Central Bus Station	3:50 AM	Roanoke, VA	Greyhound		Economy	$114	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 2/13/2026 11:25:00 AM to Greyhound, Roanoke, VA (USA) arriving at 2/14/2026 3:50:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 16h 25m

Best Price Offer: The price for the cheapest bus from Indianapolis to Roanoke, VA is $94 on 2/5/2026. Flexible travelers save on ticket prices.

Facts about the bus from Indianapolis to Roanoke, VA

Compare all providers like Greyhound US that travel 1 times every day by bus from Indianapolis to Roanoke, VA in one click! Book your bus ticket from Indianapolis to Roanoke, VA starting from $94!

Cheapest Bus	$94
Fastest Bus	16h 25m
Earliest Bus	11:25 AM
Latest Bus	11:25 AM
Daily Bus Routes	1 Ø
Distance	377.5 miles
Bus Companies	Greyhound US

Cheapest bus connections from Indianapolis to Roanoke, VA

Every day, 1 buses from 1 bus companies leave Indianapolis for Roanoke, VA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

$122

Monday 02/09

Tuesday 02/10

$155

Wednesday 02/11

$150

Thursday 02/12

Friday 02/13

$114

Saturday 02/14

Sunday 02/15

Monday 02/16

Tuesday 02/17

Wednesday 02/18

Thursday 02/19

Friday 02/20

Saturday 02/21

Sunday 02/22

Monday 02/23

Tuesday 02/24

Wednesday 02/25

Thursday 02/26

Friday 02/27

Saturday 02/28

How to save money travelling from Indianapolis to Roanoke, VA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to Roanoke, VA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to Roanoke, VA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to Roanoke, VA are also emptier.

All bus stations and stops in Indianapolis and Roanoke, VA

In the map below, you can see where to find all bus stations in Indianapolis and Roanoke, VA.

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Greyhound

Salem Ave Sw 26

Park and Ride

Hollins Shell Gas Station

Planation Rd. 8040

Service and Comfort on the bus from Indianapolis to Roanoke, VA

Want to know which seat classes are available on the buses from Indianapolis to Roanoke, VA? Or which bus companies serve the route Indianapolis to Roanoke, VA? Below you will find answers to your questions.

FAQs about the Indianapolis to Roanoke, VA bus

How much does a Indianapolis Roanoke, VA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $94 and takes 16h 25m to reach Roanoke, VA. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to Roanoke, VA?

This route is offered by 1 companies with a range of ticket prices between $94 and $155. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Roanoke, VA.

On average, how many connections are available from Indianapolis to Roanoke, VA each day?

Every day, the Indianapolis to Roanoke, VA bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to Roanoke, VA take?

The fastest bus from Indianapolis to Roanoke, VA is offered by Greyhound US and takes 16h 25m. Bus tickets for this connection cost $122. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to Roanoke, VA?

The earliest bus arriving in Roanoke, VA from Indianapolis starts at 11:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to Roanoke, VA?

The latest bus trip departing from Indianapolis for Roanoke, VA starts at 11:25 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis Roanoke, VA route?

When traveling by bus from Indianapolis to Roanoke, VA, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and Roanoke, VA?

You can check all the direct connections between Indianapolis and Roanoke, VA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Indianapolis to Roanoke, VA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis Roanoke, VA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis Roanoke, VA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to Roanoke, VA on your planned travel date.

How does CheckMyBus find the best bus deals from Indianapolis to Roanoke, VA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Indianapolis and Roanoke, VA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Indianapolis to Roanoke, VA?

Prices and availability for 1 trips between Indianapolis and Roanoke, VA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Indianapolis to Roanoke, VA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to Roanoke, VA

Here’s an overview of the most popular bus routes to Indianapolis and to Roanoke, VA. Simply click on the connection of your choice, and you will find all the details about your bus route!