Compare all timetables for the bus from Tupelo, MS to Indianapolis
Here is a selection of the cheapest bus trips from the schedule from Tupelo, MS to Indianapolis from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 30m | 9:35 PM | Tupelo, MS | Bus Stop | 12:05 PM | Indianapolis | Central Bus Station | Economy | $88 |
A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 2/5/2026 9:35:00 PM to Central Bus Station, Indianapolis (USA) arriving at 2/6/2026 12:05:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 13h 30m
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| Greyhound US | 21h 10m | 11:15 PM | Tupelo, MS | Bus Stop | 9:25 PM | Indianapolis | Washington / Delaware | Economy | $90 |
A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 2/5/2026 11:15:00 PM to Washington / Delaware, Indianapolis (USA) arriving at 2/6/2026 9:25:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 21h 10m
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| Greyhound US | 22h 10m | 5:35 AM | Tupelo, MS | Bus Stop | 4:45 AM | Indianapolis | Central Bus Station | Economy | $103 |
A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 2/5/2026 5:35:00 AM to Central Bus Station, Indianapolis (USA) arriving at 2/6/2026 4:45:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 22h 10m
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| Greyhound US | 22h 0m | 10:55 AM | Tupelo, MS | Bus Stop | 9:55 AM | Indianapolis | Central Bus Station | Economy | $103 |
A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 2/5/2026 10:55:00 AM to Central Bus Station, Indianapolis (USA) arriving at 2/6/2026 9:55:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 22h 0m
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| Greyhound US | 20h 30m | 10:55 AM | Tupelo, MS | Bus Stop | 8:25 AM | Indianapolis | Washington / Delaware | Economy | $103 |
A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 2/5/2026 10:55:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 2/6/2026 8:25:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 20h 30m
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Best Price Offer: The price for the cheapest bus from Tupelo, MS to Indianapolis is $88 on 2/5/2026. Flexible travelers save on ticket prices.
Facts about the bus from Tupelo, MS to Indianapolis
Compare all providers like Greyhound US that travel 5 times every day by bus from Tupelo, MS to Indianapolis in one click! Book your bus ticket from Tupelo, MS to Indianapolis starting from $88!
| Cheapest Bus | $88 |
| Fastest Bus | 14h 30m |
| Earliest Bus | 5:35 AM |
| Latest Bus | 11:15 PM |
| Daily Bus Routes | 5 Ø |
| Distance | 405.9 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Tupelo, MS to Indianapolis
Every day, 5 buses from 1 bus companies leave Tupelo, MS for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/02/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
02/01
Monday
02/02
Tuesday
02/03
Wednesday
02/04
Thursday
02/05
$88
Friday
02/06
Saturday
02/07
Sunday
02/08
Monday
02/09
Tuesday
02/10
$134
Wednesday
02/11
Thursday
02/12
Friday
02/13
Saturday
02/14
Sunday
02/15
Monday
02/16
Tuesday
02/17
Wednesday
02/18
Thursday
02/19
Friday
02/20
Saturday
02/21
Sunday
02/22
Monday
02/23
Tuesday
02/24
Wednesday
02/25
Thursday
02/26
Friday
02/27
Saturday
02/28
How to save money travelling from Tupelo, MS to Indianapolis
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Tupelo, MS to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tupelo, MS to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tupelo, MS to Indianapolis are also emptier.All bus stations and stops in Tupelo, MS and Indianapolis
In the map below, you can see where to find all bus stations in Tupelo, MS and Indianapolis.
Service and Comfort on the bus from Tupelo, MS to Indianapolis
Want to know which seat classes are available on the buses from Tupelo, MS to Indianapolis? Or which bus companies serve the route Tupelo, MS to Indianapolis? Below you will find answers to your questions.
FAQs about the Tupelo, MS to Indianapolis bus
How much does a Tupelo, MS Indianapolis bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $88 and takes 14h 30m to reach Indianapolis. Compare offers to save money!
How much could I save by comparing buses from Tupelo, MS to Indianapolis?
This route is offered by 1 companies with a range of ticket prices between $88 and $103. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.
On average, how many connections are available from Tupelo, MS to Indianapolis each day?
Every day, the Tupelo, MS to Indianapolis bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Tupelo, MS to Indianapolis take?
The fastest bus from Tupelo, MS to Indianapolis is offered by Greyhound US and takes 14h 30m. Bus tickets for this connection cost $88. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Tupelo, MS to Indianapolis?
The earliest bus arriving in Indianapolis from Tupelo, MS starts at 5:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Tupelo, MS to Indianapolis?
The latest bus trip departing from Tupelo, MS for Indianapolis starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Tupelo, MS Indianapolis route?
When traveling by bus from Tupelo, MS to Indianapolis, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Tupelo, MS and Indianapolis?
You can check all the direct connections between Tupelo, MS and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Tupelo, MS to Indianapolis bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tupelo, MS Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Tupelo, MS Indianapolis bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tupelo, MS to Indianapolis on your planned travel date.
How does CheckMyBus find the best bus deals from Tupelo, MS to Indianapolis?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Tupelo, MS and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Tupelo, MS to Indianapolis?
Prices and availability for 5 trips between Tupelo, MS and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Tupelo, MS to Indianapolis
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Tupelo, MS and to Indianapolis
Here’s an overview of the most popular bus routes to Tupelo, MS and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Tupelo, MS
- Buses Austin to Tupelo, MS
- Bus from Beaumont, TX to Tupelo, MS
- Bus Chicago - Tupelo, MS
- Bus to Tupelo, MS from Cincinnati
- Bus Columbia, MO to Tupelo, MS
- Bus from Dallas to Tupelo, MS
- Bus Fort Collins, CO - Tupelo, MS
- Buses Houston to Tupelo, MS
- Buses Jackson, MS - Tupelo, MS
- Buses to Tupelo, MS from Meridian, MS
- Bus from Mobile, AL to Tupelo, MS
- Bus from Owensboro, KY to Tupelo, MS
- Phoenix, AZ to Tupelo, MS bus
- Bus from Shreveport, LA to Tupelo, MS
- Buses to Tupelo, MS from Springfield, IL
- Buses to Tupelo, MS from The Woodlands, TX
- Bus Routes to Indianapolis
- Buses Allentown, PA to Indianapolis
- Bus to Indianapolis from Bloomington, IN
- Bus Boston, MA to Indianapolis
- Bus to Indianapolis from Dallas
- From Dayton, OH to Indianapolis bus
- Buses to Indianapolis from El Paso, TX
- From Eugene, OR to Indianapolis bus
- Bus to Indianapolis from Gary, IN
- Bus from Greenville, SC to Indianapolis
- Buses from Houston to Indianapolis
- Bus Knoxville, TN - Indianapolis
- Bus from Los Angeles to Indianapolis
- Buses to Indianapolis from Merrillville, IN
- Buses to Indianapolis from Philadelphia
- Bus from Saint Paul, MN to Indianapolis
- Buses San Diego - Indianapolis
- Buses from South Bend, IN to Indianapolis
- Bus to Indianapolis from Toronto, ON
- Bus Tucson, AZ - Indianapolis
- Bus to Indianapolis from Wichita, KS
Popular Airport Shuttles to Tupelo, MS and to Indianapolis
