Which bus from San Antonio, TX to Tupelo, MS is the cheapest?

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Compare all timetables for the bus from San Antonio, TX to Tupelo, MS

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Tupelo, MS from various bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US for the next days.

today
tomorrow
Thursday
Friday
Saturday
$204
Sunday
Monday

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound Lines Mexico 21h 35m 1:30 AM San Antonio, TX Bus Station 11:05 PM Tupelo, MS Bus Stop  Economy $204
Greyhound US 22h 5m 12:35 PM San Antonio, TX Bus Station 10:40 AM Tupelo, MS Bus Stop  Economy $204
FlixBus 25h 50m 9:15 PM San Antonio, TX Bus Station 11:05 PM Tupelo, MS Bus Stop  Economy $204
Greyhound Lines Mexico 26h 25m 7:00 PM San Antonio, TX Bus Station 9:25 PM Tupelo, MS Bus Stop  Economy $205
FlixBus 26h 55m 7:45 AM San Antonio, TX Pearl District 10:40 AM Tupelo, MS Bus Stop  Economy $206
  • Did you know that if you travel from San Antonio, TX to Tupelo, MS via Dallas, you can save more than $88? You can find the corresponding connections below.
    • Busbud
      27h 55m
      0
      6:45 AM
      San Antonio, TX
      Pearl District
      12:40 PM
      Dallas
      Downtown
      0
      Busbud
      Economy
      $34
      • Waiting Time 2h 50m
    • Busbud
      19h 10m
      0
      3:30 PM
      Dallas
      Downtown
      10:40 AM
      Tupelo, MS
      Bus Stop
      0
      Busbud
      Economy
      $82
    Travel time is 6h 20m longer, but you will save $88

Best Price Offer: The price for the cheapest bus from San Antonio, TX to Tupelo, MS is $149 on 2/1/2026. Flexible travelers save on ticket prices.


Facts about the bus from San Antonio, TX to Tupelo, MS

Compare all providers like FlixBus, Greyhound Lines Mexico and Greyhound US that travel 5 times every day by bus from San Antonio, TX to Tupelo, MS in one click! Book your bus ticket from San Antonio, TX to Tupelo, MS starting from $149!

Cheapest Bus $149
Fastest Bus 21h 35m
Earliest Bus 1:30 AM
Latest Bus 9:15 PM
Daily Bus Routes 5 Ø
Distance 663.8 miles
Bus Companies FlixBus, Greyhound Lines Mexico and Greyhound US

Cheapest bus connections from San Antonio, TX to Tupelo, MS

Every day, 5 buses from 3 bus companies leave San Antonio, TX for Tupelo, MS: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/03/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
$204
Sunday 02/08
Monday 02/09
Tuesday 02/10
$192
Wednesday 02/11
$175
Thursday 02/12
Friday 02/13
Saturday 02/14
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

How to save money travelling from San Antonio, TX to Tupelo, MS

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Tupelo, MS in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Tupelo, MS, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Tupelo, MS are also emptier.

All bus stations and stops in San Antonio, TX and Tupelo, MS

In the map below, you can see where to find all bus stations in San Antonio, TX and Tupelo, MS.

Service and Comfort on the bus from San Antonio, TX to Tupelo, MS

Want to know which seat classes are available on the buses from San Antonio, TX to Tupelo, MS? Or which bus companies serve the route San Antonio, TX to Tupelo, MS? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Tupelo, MS bus

How much does a San Antonio, TX Tupelo, MS bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $149 and takes 21h 35m to reach Tupelo, MS. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Tupelo, MS?

This route is offered by 3 companies with a range of ticket prices between $149 and $206. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Tupelo, MS.

On average, how many connections are available from San Antonio, TX to Tupelo, MS each day?

Every day, the San Antonio, TX to Tupelo, MS bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Tupelo, MS take?

The fastest bus from San Antonio, TX to Tupelo, MS is offered by Greyhound Lines Mexico and takes 21h 35m. Bus tickets for this connection cost $204. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Tupelo, MS?

The earliest bus arriving in Tupelo, MS from San Antonio, TX starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Tupelo, MS?

The latest bus trip departing from San Antonio, TX for Tupelo, MS starts at 9:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Tupelo, MS route?

When traveling by bus from San Antonio, TX to Tupelo, MS, passengers can travel with FlixBus, Greyhound Lines Mexico and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Tupelo, MS?

You can check all the direct connections between San Antonio, TX and Tupelo, MS by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound Lines Mexico and Greyhound US.

What can I take with me on the San Antonio, TX to Tupelo, MS bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Tupelo, MS bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Tupelo, MS bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Tupelo, MS on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to Tupelo, MS?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between San Antonio, TX and Tupelo, MS. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to Tupelo, MS?

Prices and availability for 5 trips between San Antonio, TX and Tupelo, MS change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to Tupelo, MS

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Tupelo, MS

Here’s an overview of the most popular bus routes to San Antonio, TX and to Tupelo, MS. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus Del Rio, TX to San Antonio, TX Bus Del Rio, TX to San Antonio, TX
Bus to Tupelo, MS from Newark Bus to Tupelo, MS from Newark
Bus to Tupelo, MS from Windsor, ON Bus to Tupelo, MS from Windsor, ON
Buses to Tupelo, MS from Cincinnati Buses to Tupelo, MS from Cincinnati
Bus Jackson, MS - Tupelo, MS Bus Jackson, MS - Tupelo, MS
Popular Airport Shuttles to San Antonio, TX and to Tupelo, MS
CheckMyBus › Buses in USA › Bus to San Antonio, TX › Bus to Tupelo, MS

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