Bus Itapema, SC to São Paulo - Compare all Companies

Compare all timetables for the bus from Itapema, SC to São Paulo

Here is a selection of the cheapest bus trips from the schedule from Itapema, SC to São Paulo from various bus operators like Viação Penha or Real Maia for the next days.

today

$48

tomorrow

$43

Saturday

$55

Sunday

$48

Monday

$55

Tuesday

$30

Wednesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viação Penha	11h 10m	6:50 AM	Itapema, SC	Central Bus Station	6:00 PM	São Paulo	Tietê Bus Station	Premium Economy	$48	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 4/30/2026 6:50:00 AM to Tietê Bus Station, São Paulo (Brazil) arriving at 4/30/2026 6:00:00 PM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 11h 10m
Viação Penha	11h 40m	1:30 PM	Itapema, SC	Central Bus Station	1:10 AM	São Paulo	Tietê Bus Station	Premium Economy	$56	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 4/30/2026 1:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/1/2026 1:10:00 AM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 11h 40m
Viação Penha	12h 30m	9:30 PM	Itapema, SC	Central Bus Station	10:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$57	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 4/30/2026 9:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/1/2026 10:00:00 AM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 12h 30m
Viação Penha	11h 0m	7:00 PM	Itapema, SC	Central Bus Station	6:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$60	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 4/30/2026 7:00:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/1/2026 6:00:00 AM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 11h 0m
Viação Penha	11h 15m	7:45 PM	Itapema, SC	Central Bus Station	7:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$64	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 4/30/2026 7:45:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/1/2026 7:00:00 AM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 11h 15m

Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $26? You will find the corresponding connections below.
- Save more than 54%
  
  10h 20m
  
  Itapema, SC
  
  7 mi
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0 mi
  
  Economy
  
  $22
  
  A Bus from goes from Bus Station, Balneário Camboriú (Brazil) at 4/30/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/1/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $25? You can find the corresponding connections below.
- Auto Viação Catarinense
  
  15h 35m
  
  0
  
  5:55 PM
  
  Itapema, SC
  Central Bus Station
  
  6:20 PM
  
  Balneário Camboriú
  Bus Station
  
  0
  
  Basic
  
  $1
  
  A Bus from Auto Viação Catarinense goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 5:55:00 PM to Bus Station, Balneário Camboriú (Brazil) arriving at 5/1/2026 6:20:00 PM. 50 Basic ticket for $1 per person are available. Travel duration is 0h 25m
- Busco
  
  10h 20m
  
  0
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Busco goes from Bus Station, Balneário Camboriú (Brazil) at 5/1/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Travel time is 4h 35m longer, but you will save $25

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viação Penha	11h 40m	1:30 PM	Itapema, SC	Central Bus Station	1:10 AM	São Paulo	Tietê Bus Station	Premium Economy	$43	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 1:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 1:10:00 AM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 11h 40m
Viação Penha	11h 0m	7:00 PM	Itapema, SC	Central Bus Station	6:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$43	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 7:00:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 6:00:00 AM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 11h 0m
Viação Penha	11h 15m	7:45 PM	Itapema, SC	Central Bus Station	7:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$43	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 7:45:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 7:00:00 AM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 11h 15m
Viação Penha	11h 35m	8:15 PM	Itapema, SC	Central Bus Station	7:50 AM	São Paulo	Tietê Bus Station	Premium Economy	$43	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 8:15:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 7:50:00 AM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 11h 35m
Viação Penha	12h 30m	9:30 PM	Itapema, SC	Central Bus Station	10:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$47	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 9:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 10:00:00 AM. 50 Premium Economy ticket for $47 per person are available. Travel duration is 12h 30m

Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $21? You will find the corresponding connections below.
- Save more than 49%
  
  10h 20m
  
  Itapema, SC
  
  7 mi
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0 mi
  
  Economy
  
  $22
  
  A Bus from goes from Bus Station, Balneário Camboriú (Brazil) at 5/1/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $20? You can find the corresponding connections below.
- Auto Viação Catarinense
  
  15h 35m
  
  0
  
  5:55 PM
  
  Itapema, SC
  Central Bus Station
  
  6:20 PM
  
  Balneário Camboriú
  Bus Station
  
  0
  
  Basic
  
  $1
  
  A Bus from Auto Viação Catarinense goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 5:55:00 PM to Bus Station, Balneário Camboriú (Brazil) arriving at 5/1/2026 6:20:00 PM. 50 Basic ticket for $1 per person are available. Travel duration is 0h 25m
- Busco
  
  10h 20m
  
  0
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Busco goes from Bus Station, Balneário Camboriú (Brazil) at 5/1/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Travel time is 4h 35m longer, but you will save $20

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viação Penha	11h 0m	7:00 PM	Itapema, SC	Central Bus Station	6:00 AM	São Paulo	Tietê Bus Station	Basic	$55	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/2/2026 7:00:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/3/2026 6:00:00 AM. 50 Basic ticket for $55 per person are available. Travel duration is 11h 0m
Viação Penha	11h 10m	6:50 AM	Itapema, SC	Central Bus Station	6:00 PM	São Paulo	Tietê Bus Station	Premium Economy	$59	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/2/2026 6:50:00 AM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 6:00:00 PM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 11h 10m
Viação Penha	12h 30m	9:30 PM	Itapema, SC	Central Bus Station	10:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$61	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/2/2026 9:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/3/2026 10:00:00 AM. 50 Premium Economy ticket for $61 per person are available. Travel duration is 12h 30m
Viação Penha	11h 40m	1:30 PM	Itapema, SC	Central Bus Station	1:10 AM	São Paulo	Tietê Bus Station	Premium Economy	$63	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/2/2026 1:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/3/2026 1:10:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 11h 40m
Viação Penha	11h 35m	8:15 PM	Itapema, SC	Central Bus Station	7:50 AM	São Paulo	Tietê Bus Station	Premium Economy	$63	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/2/2026 8:15:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/3/2026 7:50:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 11h 35m

Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $30? You will find the corresponding connections below.
- Save more than 55%
  
  12h 0m
  
  Itapema, SC
  
  7 mi
  
  10:00 PM
  
  Balneário Camboriú
  Bus Station
  
  10:00 AM
  
  São Paulo
  Tietê Bus Station
  
  0 mi
  
  Premium Economy
  
  $25
  
  A Bus from goes from Bus Station, Balneário Camboriú (Brazil) at 5/2/2026 10:00:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/3/2026 10:00:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 12h 0m
Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $32? You can find the corresponding connections below.
- Auto Viação Catarinense
  
  15h 35m
  
  0
  
  5:55 PM
  
  Itapema, SC
  Central Bus Station
  
  6:20 PM
  
  Balneário Camboriú
  Bus Station
  
  0
  
  Basic
  
  $1
  
  A Bus from Auto Viação Catarinense goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 5:55:00 PM to Bus Station, Balneário Camboriú (Brazil) arriving at 5/1/2026 6:20:00 PM. 50 Basic ticket for $1 per person are available. Travel duration is 0h 25m
- Busco
  
  10h 20m
  
  0
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Busco goes from Bus Station, Balneário Camboriú (Brazil) at 5/1/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Travel time is 4h 35m longer, but you will save $32

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viação Penha	11h 10m	6:50 AM	Itapema, SC	Central Bus Station	6:00 PM	São Paulo	Tietê Bus Station	Premium Economy	$48	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/3/2026 6:50:00 AM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/3/2026 6:00:00 PM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 11h 10m
Viação Penha	11h 40m	1:30 PM	Itapema, SC	Central Bus Station	1:10 AM	São Paulo	Tietê Bus Station	Premium Economy	$48	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/3/2026 1:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/4/2026 1:10:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 11h 40m
Viação Penha	11h 0m	7:00 PM	Itapema, SC	Central Bus Station	6:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$48	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/3/2026 7:00:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/4/2026 6:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 11h 0m
Viação Penha	11h 35m	8:15 PM	Itapema, SC	Central Bus Station	7:50 AM	São Paulo	Tietê Bus Station	Premium Economy	$48	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/3/2026 8:15:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/4/2026 7:50:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 11h 35m
Viação Penha	11h 15m	7:45 PM	Itapema, SC	Central Bus Station	7:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$48	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/3/2026 7:45:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/4/2026 7:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 11h 15m

Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $26? You will find the corresponding connections below.
- Save more than 54%
  
  10h 20m
  
  Itapema, SC
  
  7 mi
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0 mi
  
  Economy
  
  $22
  
  A Bus from goes from Bus Station, Balneário Camboriú (Brazil) at 5/3/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/4/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $25? You can find the corresponding connections below.
- Auto Viação Catarinense
  
  15h 35m
  
  0
  
  5:55 PM
  
  Itapema, SC
  Central Bus Station
  
  6:20 PM
  
  Balneário Camboriú
  Bus Station
  
  0
  
  Basic
  
  $1
  
  A Bus from Auto Viação Catarinense goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 5:55:00 PM to Bus Station, Balneário Camboriú (Brazil) arriving at 5/1/2026 6:20:00 PM. 50 Basic ticket for $1 per person are available. Travel duration is 0h 25m
- Busco
  
  10h 20m
  
  0
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Busco goes from Bus Station, Balneário Camboriú (Brazil) at 5/1/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Travel time is 4h 35m longer, but you will save $25

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viação Penha	11h 0m	7:00 PM	Itapema, SC	Central Bus Station	6:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$55	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/4/2026 7:00:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/5/2026 6:00:00 AM. 50 Premium Economy ticket for $55 per person are available. Travel duration is 11h 0m
Viação Penha	11h 10m	6:50 AM	Itapema, SC	Central Bus Station	6:00 PM	São Paulo	Tietê Bus Station	Premium Economy	$59	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/4/2026 6:50:00 AM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/4/2026 6:00:00 PM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 11h 10m
Viação Penha	12h 30m	9:30 PM	Itapema, SC	Central Bus Station	10:00 AM	São Paulo	Tietê Bus Station	Basic	$62	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/4/2026 9:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/5/2026 10:00:00 AM. 50 Basic ticket for $62 per person are available. Travel duration is 12h 30m
Viação Penha	11h 40m	1:30 PM	Itapema, SC	Central Bus Station	1:10 AM	São Paulo	Tietê Bus Station	Premium Economy	$63	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/4/2026 1:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/5/2026 1:10:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 11h 40m
Viação Penha	11h 35m	8:15 PM	Itapema, SC	Central Bus Station	7:50 AM	São Paulo	Tietê Bus Station	Premium Economy	$63	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/4/2026 8:15:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/5/2026 7:50:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 11h 35m

Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $33? You will find the corresponding connections below.
- Save more than 60%
  
  10h 20m
  
  Itapema, SC
  
  7 mi
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0 mi
  
  Economy
  
  $22
  
  A Bus from goes from Bus Station, Balneário Camboriú (Brazil) at 5/4/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/5/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $32? You can find the corresponding connections below.
- Auto Viação Catarinense
  
  15h 35m
  
  0
  
  5:55 PM
  
  Itapema, SC
  Central Bus Station
  
  6:20 PM
  
  Balneário Camboriú
  Bus Station
  
  0
  
  Basic
  
  $1
  
  A Bus from Auto Viação Catarinense goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 5:55:00 PM to Bus Station, Balneário Camboriú (Brazil) arriving at 5/1/2026 6:20:00 PM. 50 Basic ticket for $1 per person are available. Travel duration is 0h 25m
- Busco
  
  10h 20m
  
  0
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Busco goes from Bus Station, Balneário Camboriú (Brazil) at 5/1/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Travel time is 4h 35m longer, but you will save $32

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Real Maia	12h 30m	9:30 PM	Itapema, SC	Central Bus Station	10:00 AM	São Paulo	Tietê Bus Station	Economy	$30	A Bus from Real Maia goes from Central Bus Station, Itapema, SC (Brazil) at 5/5/2026 9:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/6/2026 10:00:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 12h 30m
Real Maia	12h 20m	9:41 PM	Itapema, SC	Central Bus Station	10:01 AM	São Paulo	Tietê Bus Station	Business	$32	A Bus from Real Maia goes from Central Bus Station, Itapema, SC (Brazil) at 5/5/2026 9:41:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/6/2026 10:01:00 AM. 50 Business ticket for $32 per person are available. Travel duration is 12h 20m
Viação Penha	11h 0m	7:00 PM	Itapema, SC	Central Bus Station	6:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$35	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/5/2026 7:00:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/6/2026 6:00:00 AM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 11h 0m
Viação Penha	11h 15m	7:45 PM	Itapema, SC	Central Bus Station	7:00 AM	São Paulo	Tietê Bus Station	Premium Economy	$35	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/5/2026 7:45:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/6/2026 7:00:00 AM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 11h 15m
Viação Penha	11h 40m	1:30 PM	Itapema, SC	Central Bus Station	1:10 AM	São Paulo	Tietê Bus Station	Basic	$36	A Bus from Viação Penha goes from Central Bus Station, Itapema, SC (Brazil) at 5/5/2026 1:30:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/6/2026 1:10:00 AM. 50 Basic ticket for $36 per person are available. Travel duration is 11h 40m

Did you know that if you travel from Itapema, SC to São Paulo via Balneário Camboriú, you can save more than $7? You can find the corresponding connections below.
- Auto Viação Catarinense
  
  15h 35m
  
  0
  
  5:55 PM
  
  Itapema, SC
  Central Bus Station
  
  6:20 PM
  
  Balneário Camboriú
  Bus Station
  
  0
  
  Basic
  
  $1
  
  A Bus from Auto Viação Catarinense goes from Central Bus Station, Itapema, SC (Brazil) at 5/1/2026 5:55:00 PM to Bus Station, Balneário Camboriú (Brazil) arriving at 5/1/2026 6:20:00 PM. 50 Basic ticket for $1 per person are available. Travel duration is 0h 25m
- Busco
  
  10h 20m
  
  0
  
  11:10 PM
  
  Balneário Camboriú
  Bus Station
  
  9:30 AM
  
  São Paulo
  Tietê Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from Busco goes from Bus Station, Balneário Camboriú (Brazil) at 5/1/2026 11:10:00 PM to Tietê Bus Station, São Paulo (Brazil) arriving at 5/2/2026 9:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 10h 20m
Travel time is 4h 35m longer, but you will save $7

Best Price Offer: The price for the cheapest bus from Itapema, SC to São Paulo is $26 on 5/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Itapema, SC and São Paulo

See here how frequent the connections between Itapema, SC and São Paulo are, during different times and days of the week.

Sunday is the busiest day, with more than 42 daily buses from Itapema, SC to São Paulo. Monday has instead the fewest connections, with only 18 daily coaches between Itapema, SC and São Paulo.

The busiest time of the day is the Evening, with 120 buses from Itapema, SC to São Paulo, while Morning sees the fewest connections between Itapema, SC and São Paulo, with 17 offers.

Facts about the bus from Itapema, SC to São Paulo

Compare all providers like Viação Penha and Real Maia that travel 28 times every day by bus from Itapema, SC to São Paulo in one click! Book your bus ticket from Itapema, SC to São Paulo starting from $26!

Cheapest Bus	$26
Fastest Bus	11h 0m
Earliest Bus	6:50 AM
Latest Bus	9:41 PM
Daily Bus Routes	28 Ø
Distance	274.2 miles
Bus Companies	Viação Penha and Real Maia

Cheapest bus connections from Itapema, SC to São Paulo

Every day, 28 buses from 2 bus companies leave Itapema, SC for São Paulo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/30/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/26

Monday 04/27

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

$48

Friday 05/01

$43

Saturday 05/02

$55

Sunday 05/03

$48

Monday 05/04

$55

Tuesday 05/05

$30

Wednesday 05/06

Thursday 05/07

Friday 05/08

$33

Saturday 05/09

$34

Sunday 05/10

$33

Monday 05/11

$33

Tuesday 05/12

$30

Wednesday 05/13

$33

Thursday 05/14

$33

Friday 05/15

$33

Saturday 05/16

$33

Sunday 05/17

$33

Monday 05/18

$33

Tuesday 05/19

$26

Wednesday 05/20

$26

Thursday 05/21

$33

Friday 05/22

$33

Saturday 05/23

The cheapest time to travel from Itapema, SC to São Paulo

See here on which day and which time of the day you can find the cheapest bus ticket from Itapema, SC to São Paulo, for the next 30 days.

With a price starting from $26, Monday is the cheapest day for a bus from Itapema, SC to São Paulo. Thursday instead is the most expensive day with prices starting from $33.

Evening is the cheapest day time for bus tickets from Itapema, SC to São Paulo, with $30. Morning is the most expensive time of the day with prices starting from $39.

How to save money travelling from Itapema, SC to São Paulo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Itapema, SC to São Paulo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Itapema, SC to São Paulo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Itapema, SC to São Paulo are also emptier.

All bus stations and stops in Itapema, SC and São Paulo

In the map below, you can see where to find all bus stations in Itapema, SC and São Paulo.

Central Bus Station

R. 600 323

Mercado Público

Morretes

R. 406 765

PEIXARIA - Sul Bus Stop

Rua Cento e Dezenove, 710 Station

Rua Cento e Dezenove, 710 Rua Cento e Dezenove, 710

Tietê Bus Station

Vila Guilherme

Barra Funda Bus Station

Rua Aloysio Biondi, s/n Barra Funda

Sala VIP Bella Vita

Av. Ordem e Progresso 95

Jabaquara Bus Station

Avenida Engenheiro Armando de Arruda Pereira 2022

Shopping Feira da Madrugada Bus Stop

Rua São Caetano 812

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Itapema, SC to São Paulo? Compare all modes of transports from Itapema, SC to São Paulo.

Service and Comfort on the bus from Itapema, SC to São Paulo

Want to know which seat classes are available on the buses from Itapema, SC to São Paulo? Or which bus companies serve the route Itapema, SC to São Paulo? Below you will find answers to your questions.

FAQs about the Itapema, SC to São Paulo bus

How much does a Itapema, SC São Paulo bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $26 and takes 12h 30m to reach São Paulo. Compare offers to save money!

How much could I save by comparing buses from Itapema, SC to São Paulo?

This route is offered by 2 companies with a range of ticket prices between $26 and $191. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to São Paulo.

On average, how many connections are available from Itapema, SC to São Paulo each day?

Every day, the Itapema, SC to São Paulo bus route is served by approximately 28 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Itapema, SC to São Paulo take?

The fastest bus from Itapema, SC to São Paulo is offered by Viação Penha and takes 11h 0m. Bus tickets for this connection cost $89. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Itapema, SC to São Paulo?

The earliest bus arriving in São Paulo from Itapema, SC starts at 6:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Itapema, SC to São Paulo?

The latest bus trip departing from Itapema, SC for São Paulo starts at 9:41 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Itapema, SC São Paulo route?

When traveling by bus from Itapema, SC to São Paulo, passengers can travel with Viação Penha and Real Maia. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Itapema, SC and São Paulo?

You can check all the direct connections between Itapema, SC and São Paulo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Viação Penha and Real Maia.

What can I take with me on the Itapema, SC to São Paulo bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Itapema, SC São Paulo bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Itapema, SC São Paulo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Itapema, SC to São Paulo on your planned travel date.

How does CheckMyBus find the best bus deals from Itapema, SC to São Paulo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 28 daily trips between Itapema, SC and São Paulo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Itapema, SC to São Paulo?

Prices and availability for 28 trips between Itapema, SC and São Paulo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Itapema, SC to São Paulo

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

More bus routes to Itapema, SC and to São Paulo

Here’s an overview of the most popular bus routes to Itapema, SC and to São Paulo. Simply click on the connection of your choice, and you will find all the details about your bus route!