Which bus from Lewiston, ME to San Diego is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $224
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Lewiston, ME to San Diego

Here is a selection of the cheapest bus trips from the schedule from Lewiston, ME to San Diego from various bus operators like Greyhound US for the next days.

today
$230
tomorrow
$277
Thursday
Friday
$226
Saturday
$251
Sunday
Monday
$235

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 80h 40m 12:40 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $230
Greyhound US 80h 35m 12:45 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $230
  • Did you know that if you travel from Lewiston, ME to San Diego via Boston, MA, you can save more than $52? You can find the corresponding connections below.
    • Greyhound US
      98h 0m
      0
      12:45 PM
      Lewiston, ME
      Bus Stop
      4:15 PM
      Boston, MA
      Atlantic and Beach St
      0
      Greyhound US
      Economy
      $22
      • Waiting Time 4h 40m
    • FlixBus
      89h 50m
      0
      8:55 PM
      Boston, MA
      Allston
      11:45 AM
      San Diego
      Old Town Transit Center
      0
      FlixBus
      Economy
      $156
    Travel time is 20h 25m longer, but you will save $52

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 80h 40m 12:40 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $277
Greyhound US 80h 35m 12:45 PM Lewiston, ME Bus Stop 6:20 PM San Diego San Ysidro Transit Center  Economy $277
  • Did you know that if you travel from Lewiston, ME to San Diego via Boston, MA, you can save more than $99? You can find the corresponding connections below.
    • Greyhound US
      98h 0m
      0
      12:45 PM
      Lewiston, ME
      Bus Stop
      4:15 PM
      Boston, MA
      Atlantic and Beach St
      0
      Greyhound US
      Economy
      $22
      • Waiting Time 4h 40m
    • FlixBus
      89h 50m
      0
      8:55 PM
      Boston, MA
      Allston
      11:45 AM
      San Diego
      Old Town Transit Center
      0
      FlixBus
      Economy
      $156
    Travel time is 20h 25m longer, but you will save $99

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 84h 35m 12:40 PM Lewiston, ME Bus Stop 10:15 PM San Diego Seaport Village  Economy $226
Greyhound US 79h 55m 12:40 PM Lewiston, ME Bus Stop 5:35 PM San Diego La Jolla Village  Economy $226
Greyhound US 79h 50m 12:45 PM Lewiston, ME Bus Stop 5:35 PM San Diego La Jolla Village  Economy $226
Greyhound US 80h 30m 12:40 PM Lewiston, ME Bus Stop 6:10 PM San Diego Old Town Transit Center  Economy $226
Greyhound US 80h 25m 12:45 PM Lewiston, ME Bus Stop 6:10 PM San Diego Old Town Transit Center  Economy $226
  • Did you know that if you travel from Lewiston, ME to San Diego via Boston, MA, you can save more than $67? You can find the corresponding connections below.
    • Greyhound US
      102h 10m
      0
      12:45 PM
      Lewiston, ME
      Bus Stop
      4:15 PM
      Boston, MA
      Atlantic and Beach St
      0
      Greyhound US
      Economy
      $41
      • Waiting Time 20h 15m
    • Greyhound US
      78h 25m
      0
      12:30 PM
      Boston, MA
      South Station
      3:55 PM
      San Diego
      La Jolla Village
      0
      Greyhound US
      Economy
      $118
    Travel time is 25h 20m longer, but you will save $67

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 84h 35m 12:40 PM Lewiston, ME Bus Stop 10:15 PM San Diego Seaport Village  Economy $251
Greyhound US 80h 5m 12:40 PM Lewiston, ME Bus Stop 5:45 PM San Diego Old Town Transit Center  Economy $251
Greyhound US 80h 0m 12:45 PM Lewiston, ME Bus Stop 5:45 PM San Diego Old Town Transit Center  Economy $251
Greyhound US 84h 30m 12:45 PM Lewiston, ME Bus Stop 10:15 PM San Diego Seaport Village  Economy $253
Greyhound US 80h 30m 12:40 PM Lewiston, ME Bus Stop 6:10 PM San Diego Old Town Transit Center  Economy $255
  • Did you know that if you travel from Lewiston, ME to San Diego via Boston, MA, you can save more than $99? You can find the corresponding connections below.
    • Greyhound US
      79h 50m
      0
      12:45 PM
      Lewiston, ME
      Bus Stop
      4:15 PM
      Boston, MA
      Atlantic and Beach St
      0
      Greyhound US
      Economy
      $41
      • Waiting Time 3h 20m
    • Greyhound US
      73h 0m
      0
      7:35 PM
      Boston, MA
      South Station
      5:35 PM
      San Diego
      La Jolla Village
      0
      Greyhound US
      Economy
      $111
    Travel time is 2h 50m longer, but you will save $99

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 84h 30m 12:45 PM Lewiston, ME Bus Stop 10:15 PM San Diego Seaport Village  Economy $235
Greyhound US 84h 35m 12:40 PM Lewiston, ME Bus Stop 10:15 PM San Diego Seaport Village  Economy $236
Greyhound US 86h 10m 12:40 PM Lewiston, ME Bus Stop 11:50 PM San Diego Old Town Transit Center  Economy $236
Greyhound US 86h 5m 12:45 PM Lewiston, ME Bus Stop 11:50 PM San Diego Old Town Transit Center  Economy $236
Greyhound US 80h 30m 12:40 PM Lewiston, ME Bus Stop 6:10 PM San Diego Old Town Transit Center  Economy $239
  • Did you know that if you travel from Lewiston, ME to San Diego via Boston, MA, you can save more than $111? You can find the corresponding connections below.
    • Greyhound US
      80h 0m
      0
      12:45 PM
      Lewiston, ME
      Bus Stop
      4:15 PM
      Boston, MA
      Atlantic and Beach St
      0
      Greyhound US
      Economy
      $22
      • Waiting Time 3h 20m
    • Greyhound US
      73h 10m
      0
      7:35 PM
      Boston, MA
      South Station
      5:45 PM
      San Diego
      Old Town Transit Center
      0
      Greyhound US
      Economy
      $102
    Travel time is 2h 30m longer, but you will save $111

Best Price Offer: The price for the cheapest bus from Lewiston, ME to San Diego is $224 on 5/26/2026. Flexible travelers save on ticket prices.


Facts about the bus from Lewiston, ME to San Diego

Compare all providers like Greyhound US that travel 6 times every day by bus from Lewiston, ME to San Diego in one click! Book your bus ticket from Lewiston, ME to San Diego starting from $224!

Cheapest Bus $224
Fastest Bus 76h 50m
Earliest Bus 12:40 PM
Latest Bus 12:45 PM
Daily Bus Routes 6 Ø
Distance 2,621.9 miles
Bus Companies Greyhound US

Cheapest bus connections from Lewiston, ME to San Diego

Every day, 6 buses from 1 bus companies leave Lewiston, ME for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/19/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/17
Monday 05/18
Tuesday 05/19
$230
Wednesday 05/20
$277
Thursday 05/21
Friday 05/22
$228
Saturday 05/23
$251
Sunday 05/24
Monday 05/25
$239
Tuesday 05/26
$224
Wednesday 05/27
Thursday 05/28
$239
Friday 05/29
$231
Saturday 05/30
$232
Sunday 05/31
$245
Monday 06/01
$228
Tuesday 06/02
Wednesday 06/03
$235
Thursday 06/04
$235
Friday 06/05
Saturday 06/06
$226
Sunday 06/07
$226
Monday 06/08
$232
Tuesday 06/09
$228
Wednesday 06/10
Thursday 06/11
$229
Friday 06/12
Saturday 06/13

How to save money travelling from Lewiston, ME to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lewiston, ME to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lewiston, ME to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lewiston, ME to San Diego are also emptier.

Beloved bus companies from Lewiston, ME to San Diego

These are the most booked bus companies between Lewiston, ME to San Diego from our users.

Greyhound US from Lewiston, ME to San Diego

Greyhound US

Here you will find the key facts about the Greyhound US bus route Lewiston, ME to San Diego:

Cheapest Price $226
Fastest Bus 76h 50m
Earliest Bus 12:40 PM
Last Bus 12:45 PM
Daily Connections 6 Ø
Found on 4/25/2026

All bus stations and stops in Lewiston, ME and San Diego

In the map below, you can see where to find all bus stations in Lewiston, ME and San Diego.

Service and Comfort on the bus from Lewiston, ME to San Diego

Want to know which seat classes are available on the buses from Lewiston, ME to San Diego? Or which bus companies serve the route Lewiston, ME to San Diego? Below you will find answers to your questions.

FAQs about the Lewiston, ME to San Diego bus

How much does a Lewiston, ME San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $224 and takes 81h 35m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Lewiston, ME to San Diego?

This route is offered by 1 companies with a range of ticket prices between $224 and $277. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Lewiston, ME to San Diego each day?

Every day, the Lewiston, ME to San Diego bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lewiston, ME to San Diego take?

The fastest bus from Lewiston, ME to San Diego is offered by Greyhound US and takes 76h 50m. Bus tickets for this connection cost $226. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lewiston, ME to San Diego?

The earliest bus arriving in San Diego from Lewiston, ME starts at 12:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lewiston, ME to San Diego?

The latest bus trip departing from Lewiston, ME for San Diego starts at 12:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lewiston, ME San Diego route?

When traveling by bus from Lewiston, ME to San Diego, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lewiston, ME and San Diego?

You can check all the direct connections between Lewiston, ME and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Lewiston, ME to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lewiston, ME San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lewiston, ME San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lewiston, ME to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Lewiston, ME to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Lewiston, ME and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lewiston, ME to San Diego?

Prices and availability for 6 trips between Lewiston, ME and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lewiston, ME to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lewiston, ME and to San Diego

Here’s an overview of the most popular bus routes to Lewiston, ME and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to Lewiston, ME from Orlando, FL Buses to Lewiston, ME from Orlando, FL
Bus to Lewiston, ME from Newark Bus to Lewiston, ME from Newark
Bus Florence, SC to Lewiston, ME Bus Florence, SC to Lewiston, ME
Bus Richmond, VA - Lewiston, ME Bus Richmond, VA - Lewiston, ME
Bus Barstow, CA to San Diego Bus Barstow, CA to San Diego
Gilroy, CA to San Diego bus Gilroy, CA to San Diego bus
Buses Las Cruces, NM - San Diego Buses Las Cruces, NM - San Diego
Oxnard, CA to San Diego bus Oxnard, CA to San Diego bus
Popular Airport Shuttles to Lewiston, ME and to San Diego
CheckMyBus › Buses in USA › Bus to Lewiston, ME › Bus to San Diego

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.