Bus Lucerne to Brussels: Compare prices and save money

Compare all timetables for the bus from Lucerne to Brussels

Here is a selection of the cheapest bus trips from the schedule from Lucerne to Brussels from various bus operators like FlixBus for the next days.

today

tomorrow

$43

Wednesday

$42

Thursday

Friday

$59

Saturday

$50

Sunday

$54

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	9h 20m	2:15 AM	Lucerne	Bus Station Inselipark	11:35 AM	Brussels	North Station		Economy	$43	A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/21/2026 2:15:00 AM to North Station, Brussels (Belgium) arriving at 4/21/2026 11:35:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 9h 20m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	9h 20m	2:15 AM	Lucerne	Bus Station Inselipark	11:35 AM	Brussels	North Station		Economy	$42	A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/22/2026 2:15:00 AM to North Station, Brussels (Belgium) arriving at 4/22/2026 11:35:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 9h 20m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 10m	4:25 AM	Lucerne	Bus Station Inselipark	8:35 PM	Brussels	North Station	Economy	$59	A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/24/2026 4:25:00 AM to North Station, Brussels (Belgium) arriving at 4/24/2026 8:35:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 16h 10m
FlixBus	14h 15m	4:30 PM	Lucerne	Bus Station Inselipark	6:45 AM	Brussels	North Station	Economy	$63	A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/24/2026 4:30:00 PM to North Station, Brussels (Belgium) arriving at 4/25/2026 6:45:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 14h 15m
FlixBus	19h 5m	4:25 AM	Lucerne	Bus Station Inselipark	11:30 PM	Brussels	Midi Bus Station	Economy	$63	A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/24/2026 4:25:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 4/24/2026 11:30:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 19h 5m
FlixBus	20h 15m	4:30 PM	Lucerne	Bus Station Inselipark	12:45 PM	Brussels	Midi Bus Station	Economy	$81	A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/24/2026 4:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 4/25/2026 12:45:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 20h 15m

Did you know that if you travel from Lucerne to Brussels via Antwerp, you can save more than $10? You can find the corresponding connections below.
- FlixBus
  
  13h 50m
  
  0
  
  2:15 AM
  
  Lucerne
  Bus Station Inselipark
  
  12:40 PM
  
  Antwerp
  Van Stralenstraat
  
  0
  
  Economy
  
  $44
  
  A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/22/2026 2:15:00 AM to Van Stralenstraat, Antwerp (Belgium) arriving at 4/22/2026 12:40:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 10h 25m
- FlixBus
  
  0h 45m
  
  0
  
  3:20 PM
  
  Antwerp
  Van Stralenstraat
  
  4:05 PM
  
  Brussels
  North Station
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Van Stralenstraat, Antwerp (Belgium) at 4/22/2026 3:20:00 PM to North Station, Brussels (Belgium) arriving at 4/22/2026 4:05:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 45m
Travel Time is 0h 25m shorter, and you will save $10

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	9h 20m	2:15 AM	Lucerne	Bus Station Inselipark	11:35 AM	Brussels	North Station		Economy	$50	A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/25/2026 2:15:00 AM to North Station, Brussels (Belgium) arriving at 4/25/2026 11:35:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 9h 20m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	9h 20m	2:15 AM	Lucerne	Bus Station Inselipark	11:35 AM	Brussels	North Station		Economy	$54	A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/26/2026 2:15:00 AM to North Station, Brussels (Belgium) arriving at 4/26/2026 11:35:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 9h 20m

Did you know that if you travel from Lucerne to Brussels via Antwerp, you can save more than $5? You can find the corresponding connections below.
- FlixBus
  
  13h 50m
  
  0
  
  2:15 AM
  
  Lucerne
  Bus Station Inselipark
  
  12:40 PM
  
  Antwerp
  Van Stralenstraat
  
  0
  
  Economy
  
  $44
  
  A Bus from FlixBus goes from Bus Station Inselipark, Lucerne (Switzerland) at 4/22/2026 2:15:00 AM to Van Stralenstraat, Antwerp (Belgium) arriving at 4/22/2026 12:40:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 10h 25m
- FlixBus
  
  0h 45m
  
  0
  
  3:20 PM
  
  Antwerp
  Van Stralenstraat
  
  4:05 PM
  
  Brussels
  North Station
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Van Stralenstraat, Antwerp (Belgium) at 4/22/2026 3:20:00 PM to North Station, Brussels (Belgium) arriving at 4/22/2026 4:05:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 45m
Travel time is 4h 30m longer, but you will save $5

Best Price Offer: The price for the cheapest bus from Lucerne to Brussels is $42 on 4/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Lucerne and Brussels

See here how frequent the connections between Lucerne and Brussels are, during different times and days of the week.

Friday is the busiest day, with more than 4 daily buses from Lucerne to Brussels. Sunday has instead the fewest connections, with only 1 daily coaches between Lucerne and Brussels.

The busiest time of the day is the Night, with 6 buses from Lucerne to Brussels, while Afternoon sees the fewest connections between Lucerne and Brussels, with 2 offers.

Facts about the bus from Lucerne to Brussels

Compare all providers like FlixBus that travel 1 times every day by bus from Lucerne to Brussels in one click! Book your bus ticket from Lucerne to Brussels starting from $42!

Cheapest Bus	$42
Fastest Bus	9h 20m
Earliest Bus	2:15 AM
Latest Bus	2:15 AM
Daily Bus Routes	1 Ø
Distance	318.1 miles
Bus Companies	FlixBus

Cheapest bus connections from Lucerne to Brussels

Every day, 1 buses from 1 bus companies leave Lucerne for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

Tuesday 04/21

$43

Wednesday 04/22

$42

Thursday 04/23

Friday 04/24

$59

Saturday 04/25

$50

Sunday 04/26

$54

Monday 04/27

$55

Tuesday 04/28

$49

Wednesday 04/29

Thursday 04/30

$58

Friday 05/01

Saturday 05/02

Sunday 05/03

Monday 05/04

$50

Tuesday 05/05

$50

Wednesday 05/06

Thursday 05/07

Friday 05/08

$70

Saturday 05/09

$58

Sunday 05/10

$58

Monday 05/11

$53

Tuesday 05/12

Wednesday 05/13

Thursday 05/14

$85

Friday 05/15

$82

Saturday 05/16

The cheapest time to travel from Lucerne to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Lucerne to Brussels, for the next 30 days.

With a price starting from $42, Wednesday is the cheapest day for a bus from Lucerne to Brussels. Friday instead is the most expensive day with prices starting from $59.

Night is the cheapest day time for bus tickets from Lucerne to Brussels, with $42. Afternoon is the most expensive time of the day with prices starting from $63.

How to save money travelling from Lucerne to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lucerne to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lucerne to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lucerne to Brussels are also emptier.

Beloved bus companies from Lucerne to Brussels

These are the most booked bus companies between Lucerne to Brussels from our users.

FlixBus from Lucerne to Brussels

Here you will find the key facts about the FlixBus bus route Lucerne to Brussels:

Cheapest Price	$42
Fastest Bus	9h 20m
Earliest Bus	2:15 AM
Last Bus	2:15 AM
Daily Connections	1 Ø
Found on	3/27/2026

All bus stations and stops in Lucerne and Brussels

In the map below, you can see where to find all bus stations in Lucerne and Brussels.

Bus Station Inselipark

Europaplatz / Inseliquai 1

Central Bus Station

West

Autobahnraststätte West (Richtung Luzern) 1

Eichhof Bus Stop

Pilatusplatz Bus Stop

Midi Bus Station

Avenue Fonsny 1

North Station

Rue du Progrès 80

Congrès

Boulevard Pachéco 7

Central Station

Delta

PONT DU, Boulevard des Invalides, 1160 BRUXELLES, Belgium

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Lucerne to Brussels? Compare all modes of transports from Lucerne to Brussels.

Service and Comfort on the bus from Lucerne to Brussels

Want to know which seat classes are available on the buses from Lucerne to Brussels? Or which bus companies serve the route Lucerne to Brussels? Below you will find answers to your questions.

FAQs about the Lucerne to Brussels bus

How much does a Lucerne Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 9h 20m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Lucerne to Brussels?

This route is offered by 1 companies with a range of ticket prices between $42 and $81. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Lucerne to Brussels each day?

Every day, the Lucerne to Brussels bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lucerne to Brussels take?

The fastest bus from Lucerne to Brussels is offered by FlixBus and takes 9h 20m. Bus tickets for this connection cost $43. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lucerne to Brussels?

The earliest bus arriving in Brussels from Lucerne starts at 2:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lucerne to Brussels?

The latest bus trip departing from Lucerne for Brussels starts at 2:15 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lucerne Brussels route?

When traveling by bus from Lucerne to Brussels, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lucerne and Brussels?

You can check all the direct connections between Lucerne and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Lucerne to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lucerne Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lucerne Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lucerne to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Lucerne to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Lucerne and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lucerne to Brussels?

Prices and availability for 1 trips between Lucerne and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lucerne to Brussels

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lucerne and to Brussels

Here’s an overview of the most popular bus routes to Lucerne and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!