Bus McAllen, TX to Indianapolis: Compare prices and save money

Compare all timetables for the bus from McAllen, TX to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from McAllen, TX to Indianapolis from various bus operators like Valley Transit, FlixBus or Greyhound Lines Mexico for the next days.

today

tomorrow

Saturday

$105

Sunday

$108

Monday

$111

Tuesday

$115

Wednesday

$123

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	39h 20m	4:05 PM	McAllen, TX	Central Bus Station	8:25 AM	Indianapolis	Downtown Transit Center	Economy	$105	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/9/2026 4:05:00 PM to Downtown Transit Center, Indianapolis (USA) arriving at 5/11/2026 8:25:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 39h 20m
Valley Transit	35h 40m	4:05 PM	McAllen, TX	Central Bus Station	4:45 AM	Indianapolis	Central Bus Station	Economy	$105	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/9/2026 4:05:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/11/2026 4:45:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 35h 40m
Valley Transit	37h 50m	6:35 AM	McAllen, TX	Central Bus Station	9:25 PM	Indianapolis	Downtown Transit Center	Economy	$106	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/9/2026 6:35:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 5/10/2026 9:25:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 37h 50m
Valley Transit	33h 0m	6:35 AM	McAllen, TX	Central Bus Station	4:35 PM	Indianapolis	Central Bus Station	Economy	$106	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/9/2026 6:35:00 AM to Central Bus Station, Indianapolis (USA) arriving at 5/10/2026 4:35:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 33h 0m
Valley Transit	35h 50m	11:15 PM	McAllen, TX	Central Bus Station	12:05 PM	Indianapolis	Central Bus Station	Economy	$107	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/9/2026 11:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/11/2026 12:05:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 35h 50m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	37h 50m	6:35 AM	McAllen, TX	Central Bus Station	9:25 PM	Indianapolis	Downtown Transit Center	Economy	$108	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/10/2026 6:35:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 5/11/2026 9:25:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 37h 50m
Valley Transit	39h 20m	4:05 PM	McAllen, TX	Central Bus Station	8:25 AM	Indianapolis	Downtown Transit Center	Economy	$108	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/10/2026 4:05:00 PM to Downtown Transit Center, Indianapolis (USA) arriving at 5/12/2026 8:25:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 39h 20m
Valley Transit	33h 0m	6:35 AM	McAllen, TX	Central Bus Station	4:35 PM	Indianapolis	Central Bus Station	Economy	$108	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/10/2026 6:35:00 AM to Central Bus Station, Indianapolis (USA) arriving at 5/11/2026 4:35:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 33h 0m
Valley Transit	35h 50m	11:15 PM	McAllen, TX	Central Bus Station	12:05 PM	Indianapolis	Central Bus Station	Economy	$108	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/10/2026 11:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/12/2026 12:05:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 35h 50m
Valley Transit	35h 40m	4:05 PM	McAllen, TX	Central Bus Station	4:45 AM	Indianapolis	Central Bus Station	Economy	$109	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/10/2026 4:05:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/12/2026 4:45:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 35h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	41h 5m	2:20 PM	McAllen, TX	Central Bus Station	8:25 AM	Indianapolis	Downtown Transit Center	Economy	$111	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 5/11/2026 2:20:00 PM to Downtown Transit Center, Indianapolis (USA) arriving at 5/13/2026 8:25:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 41h 5m
Valley Transit	37h 50m	6:35 AM	McAllen, TX	Central Bus Station	9:25 PM	Indianapolis	Downtown Transit Center	Economy	$112	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/11/2026 6:35:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 5/12/2026 9:25:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 37h 50m
Valley Transit	33h 0m	6:35 AM	McAllen, TX	Central Bus Station	4:35 PM	Indianapolis	Central Bus Station	Economy	$112	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/11/2026 6:35:00 AM to Central Bus Station, Indianapolis (USA) arriving at 5/12/2026 4:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 33h 0m
Valley Transit	35h 50m	11:15 PM	McAllen, TX	Central Bus Station	12:05 PM	Indianapolis	Central Bus Station	Economy	$112	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/11/2026 11:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/13/2026 12:05:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 35h 50m
Greyhound US	37h 25m	2:20 PM	McAllen, TX	Central Bus Station	4:45 AM	Indianapolis	Central Bus Station	Economy	$112	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 5/11/2026 2:20:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/13/2026 4:45:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 37h 25m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	33h 0m	6:35 AM	McAllen, TX	Central Bus Station	4:35 PM	Indianapolis	Central Bus Station	Economy	$115	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/12/2026 6:35:00 AM to Central Bus Station, Indianapolis (USA) arriving at 5/13/2026 4:35:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 33h 0m
Valley Transit	35h 50m	11:15 PM	McAllen, TX	Central Bus Station	12:05 PM	Indianapolis	Central Bus Station	Economy	$115	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/12/2026 11:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/14/2026 12:05:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 35h 50m
Valley Transit	37h 50m	6:35 AM	McAllen, TX	Central Bus Station	9:25 PM	Indianapolis	Downtown Transit Center	Economy	$115	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/12/2026 6:35:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 5/13/2026 9:25:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 37h 50m
Greyhound Lines Mexico	44h 5m	11:20 AM	McAllen, TX	Central Bus Station	8:25 AM	Indianapolis	Downtown Transit Center	Economy	$119	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 5/12/2026 11:20:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 5/14/2026 8:25:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 44h 5m
Greyhound Lines Mexico	40h 25m	11:20 AM	McAllen, TX	Central Bus Station	4:45 AM	Indianapolis	Central Bus Station	Economy	$121	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 5/12/2026 11:20:00 AM to Central Bus Station, Indianapolis (USA) arriving at 5/14/2026 4:45:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 40h 25m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	35h 40m	4:05 PM	McAllen, TX	Central Bus Station	4:45 AM	Indianapolis	Central Bus Station	Economy	$123	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/13/2026 4:05:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/15/2026 4:45:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 35h 40m
Valley Transit	39h 20m	4:05 PM	McAllen, TX	Central Bus Station	8:25 AM	Indianapolis	Downtown Transit Center	Economy	$123	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/13/2026 4:05:00 PM to Downtown Transit Center, Indianapolis (USA) arriving at 5/15/2026 8:25:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 39h 20m
Valley Transit	35h 50m	11:15 PM	McAllen, TX	Central Bus Station	12:05 PM	Indianapolis	Central Bus Station	Economy	$124	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/13/2026 11:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 5/15/2026 12:05:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 35h 50m
Valley Transit	37h 50m	6:35 AM	McAllen, TX	Central Bus Station	9:25 PM	Indianapolis	Downtown Transit Center	Economy	$124	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/13/2026 6:35:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 5/14/2026 9:25:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 37h 50m
Valley Transit	33h 0m	6:35 AM	McAllen, TX	Central Bus Station	4:35 PM	Indianapolis	Central Bus Station	Economy	$125	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 5/13/2026 6:35:00 AM to Central Bus Station, Indianapolis (USA) arriving at 5/14/2026 4:35:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 33h 0m

Best Price Offer: The price for the cheapest bus from McAllen, TX to Indianapolis is $105 on 5/9/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between McAllen, TX and Indianapolis

See here how frequent the connections between McAllen, TX and Indianapolis are, during different times and days of the week.

Wednesday is the busiest day, with more than 8 daily buses from McAllen, TX to Indianapolis. Sunday has instead the fewest connections, with only 5 daily coaches between McAllen, TX and Indianapolis.

The busiest time of the day is the Morning, with 16 buses from McAllen, TX to Indianapolis, while Evening sees the fewest connections between McAllen, TX and Indianapolis, with 7 offers.

Facts about the bus from McAllen, TX to Indianapolis

Compare all providers like Valley Transit, FlixBus and Greyhound Lines Mexico that travel 6 times every day by bus from McAllen, TX to Indianapolis in one click! Book your bus ticket from McAllen, TX to Indianapolis starting from $105!

Cheapest Bus	$105
Fastest Bus	34h 0m
Earliest Bus	6:35 AM
Latest Bus	11:15 PM
Daily Bus Routes	6 Ø
Distance	1,167.6 miles
Bus Companies	Valley Transit, FlixBus, Greyhound Lines Mexico and Greyhound US

Cheapest bus connections from McAllen, TX to Indianapolis

Every day, 6 buses from 4 bus companies leave McAllen, TX for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$107

Saturday 05/09

$109

Sunday 05/10

$108

Monday 05/11

$111

Tuesday 05/12

$115

Wednesday 05/13

$127

Thursday 05/14

$124

Friday 05/15

Saturday 05/16

$125

Sunday 05/17

$115

Monday 05/18

$116

Tuesday 05/19

$134

Wednesday 05/20

$133

Thursday 05/21

$138

Friday 05/22

$145

Saturday 05/23

$143

Sunday 05/24

$127

Monday 05/25

$128

Tuesday 05/26

Wednesday 05/27

$122

Thursday 05/28

$134

Friday 05/29

Saturday 05/30

The cheapest time to travel from McAllen, TX to Indianapolis

See here on which day and which time of the day you can find the cheapest bus ticket from McAllen, TX to Indianapolis, for the next 30 days.

With a price starting from $105, Saturday is the cheapest day for a bus from McAllen, TX to Indianapolis. Wednesday instead is the most expensive day with prices starting from $122.

Afternoon is the cheapest day time for bus tickets from McAllen, TX to Indianapolis, with $105. Evening is the most expensive time of the day with prices starting from $107.

How to save money travelling from McAllen, TX to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from McAllen, TX to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from McAllen, TX to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from McAllen, TX to Indianapolis are also emptier.

Beloved bus companies from McAllen, TX to Indianapolis

These are the most booked bus companies between McAllen, TX to Indianapolis from our users.

Valley Transit from McAllen, TX to Indianapolis

Here you will find the key facts about the Valley Transit bus route McAllen, TX to Indianapolis:

Cheapest Price	$105
Fastest Bus	34h 0m
Earliest Bus	6:35 AM
Last Bus	11:15 PM
Daily Connections	4 Ø
Found on	4/12/2026

FlixBus from McAllen, TX to Indianapolis

Here you will find the key facts about the FlixBus bus route McAllen, TX to Indianapolis:

Cheapest Price	$109
Fastest Bus	36h 50m
Earliest Bus	6:35 AM
Last Bus	11:15 PM
Daily Connections	3 Ø
Found on	4/12/2026

All bus stations and stops in McAllen, TX and Indianapolis

In the map below, you can see where to find all bus stations in McAllen, TX and Indianapolis.

Central Bus Station

U.S. 83 Business 1501

Frontera México-USA

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Service and Comfort on the bus from McAllen, TX to Indianapolis

Want to know which seat classes are available on the buses from McAllen, TX to Indianapolis? Or which bus companies serve the route McAllen, TX to Indianapolis? Below you will find answers to your questions.

FAQs about the McAllen, TX to Indianapolis bus

How much does a McAllen, TX Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $105 and takes 40h 20m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from McAllen, TX to Indianapolis?

This route is offered by 4 companies with a range of ticket prices between $105 and $128. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from McAllen, TX to Indianapolis each day?

Every day, the McAllen, TX to Indianapolis bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from McAllen, TX to Indianapolis take?

The fastest bus from McAllen, TX to Indianapolis is offered by Valley Transit and takes 34h 0m. Bus tickets for this connection cost $106. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from McAllen, TX to Indianapolis?

The earliest bus arriving in Indianapolis from McAllen, TX starts at 6:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from McAllen, TX to Indianapolis?

The latest bus trip departing from McAllen, TX for Indianapolis starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the McAllen, TX Indianapolis route?

When traveling by bus from McAllen, TX to Indianapolis, passengers can travel with Valley Transit, FlixBus and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between McAllen, TX and Indianapolis?

You can check all the direct connections between McAllen, TX and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Valley Transit, FlixBus and Greyhound Lines Mexico.

What can I take with me on the McAllen, TX to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the McAllen, TX Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the McAllen, TX Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from McAllen, TX to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from McAllen, TX to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between McAllen, TX and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from McAllen, TX to Indianapolis?

Prices and availability for 6 trips between McAllen, TX and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route McAllen, TX to Indianapolis

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to McAllen, TX and to Indianapolis

Here’s an overview of the most popular bus routes to McAllen, TX and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!