Bus McAllen, TX to San Diego - Compare all Companies

Compare all timetables for the bus from McAllen, TX to San Diego

Here is a selection of the cheapest bus trips from the schedule from McAllen, TX to San Diego from various bus operators like FlixBus or Greyhound Lines Mexico for the next days.

today

$223

tomorrow

$220

Saturday

$226

Sunday

$235

Monday

$306

Tuesday

$225

Wednesday

$272

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	41h 25m	11:15 PM	McAllen, TX	Central Bus Station	2:40 PM	San Diego	San Ysidro Transit Center		Economy	$223	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/18/2025 11:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/20/2025 2:40:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 41h 25m
	Greyhound Lines Mexico	49h 15m	11:20 AM	McAllen, TX	Central Bus Station	10:35 AM	San Diego	San Ysidro Transit Center		Economy	$294	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/18/2025 11:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/20/2025 10:35:00 AM. 50 Economy ticket for $294 per person are available. Travel duration is 49h 15m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	41h 25m	11:15 PM	McAllen, TX	Central Bus Station	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$220	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/19/2025 11:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/21/2025 2:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 41h 25m
Greyhound Lines Mexico	49h 15m	11:20 AM	McAllen, TX	Central Bus Station	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$322	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/19/2025 11:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/21/2025 10:35:00 AM. 50 Economy ticket for $322 per person are available. Travel duration is 49h 15m
FlixBus	40h 55m	11:15 PM	McAllen, TX	Central Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$360	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/19/2025 11:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/21/2025 2:10:00 PM. 50 Economy ticket for $360 per person are available. Travel duration is 40h 55m
FlixBus	40h 25m	11:15 PM	McAllen, TX	Central Bus Station	1:40 PM	San Diego	La Jolla Village	Economy	$360	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/19/2025 11:15:00 PM to La Jolla Village, San Diego (USA) arriving at 12/21/2025 1:40:00 PM. 50 Economy ticket for $360 per person are available. Travel duration is 40h 25m
Greyhound Lines Mexico	48h 45m	11:20 AM	McAllen, TX	Central Bus Station	10:05 AM	San Diego	Seaport Village	Economy	$469	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/19/2025 11:20:00 AM to Seaport Village, San Diego (USA) arriving at 12/21/2025 10:05:00 AM. 50 Economy ticket for $469 per person are available. Travel duration is 48h 45m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	41h 25m	11:15 PM	McAllen, TX	Central Bus Station	2:40 PM	San Diego	San Ysidro Transit Center		Economy	$226	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/20/2025 11:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/22/2025 2:40:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 41h 25m
	Greyhound Lines Mexico	49h 15m	11:20 AM	McAllen, TX	Central Bus Station	10:35 AM	San Diego	San Ysidro Transit Center		Economy	$243	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/20/2025 11:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/22/2025 10:35:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 49h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	43h 55m	11:15 PM	McAllen, TX	Central Bus Station	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$235	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/21/2025 11:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/23/2025 5:10:00 PM. 50 Economy ticket for $235 per person are available. Travel duration is 43h 55m
FlixBus	46h 10m	10:10 PM	McAllen, TX	Central Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$239	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/21/2025 10:10:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/23/2025 6:20:00 PM. 50 Economy ticket for $239 per person are available. Travel duration is 46h 10m
FlixBus	49h 30m	11:15 PM	McAllen, TX	Central Bus Station	10:45 PM	San Diego	San Ysidro Transit Center	Economy	$247	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/21/2025 11:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/23/2025 10:45:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 49h 30m
Greyhound Lines Mexico	49h 15m	11:20 AM	McAllen, TX	Central Bus Station	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$259	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/21/2025 11:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/23/2025 10:35:00 AM. 50 Economy ticket for $259 per person are available. Travel duration is 49h 15m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound Lines Mexico	49h 15m	11:20 AM	McAllen, TX	Central Bus Station	10:35 AM	San Diego	San Ysidro Transit Center		Economy	$306	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/22/2025 11:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/24/2025 10:35:00 AM. 50 Economy ticket for $306 per person are available. Travel duration is 49h 15m

Did you know that if you travel from McAllen, TX to San Diego via Reynosa, you can save more than $78? You can find the corresponding connections below.
- Busbud
  
  48h 10m
  
  0
  
  3:30 PM
  
  McAllen, TX
  Central Bus Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $6
  
  A Bus from Busbud goes from Central Bus Station, McAllen, TX (USA) at 12/19/2025 3:30:00 PM to Hotel City Express, Reynosa (Mexico) arriving at 12/19/2025 5:00:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 30m
- FlixBus
  
  46h 10m
  
  0
  
  5:30 PM
  
  Reynosa
  Central Bus Station
  
  1:40 PM
  
  San Diego
  La Jolla Village
  
  0
  
  Economy
  
  $222
  
  A Bus from FlixBus goes from Central Bus Station, Reynosa (Mexico) at 12/19/2025 5:30:00 PM to La Jolla Village, San Diego (USA) arriving at 12/21/2025 1:40:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 46h 10m
Travel time is 0h 55m longer, but you will save $78

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	41h 25m	11:15 PM	McAllen, TX	Central Bus Station	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$225	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/23/2025 11:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/25/2025 2:40:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 41h 25m
Greyhound Lines Mexico	51h 0m	11:20 AM	McAllen, TX	Central Bus Station	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$251	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/23/2025 11:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/25/2025 12:20:00 PM. 50 Economy ticket for $251 per person are available. Travel duration is 51h 0m
FlixBus	40h 55m	11:15 PM	McAllen, TX	Central Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$296	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/23/2025 11:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/25/2025 2:10:00 PM. 50 Economy ticket for $296 per person are available. Travel duration is 40h 55m
FlixBus	40h 25m	11:15 PM	McAllen, TX	Central Bus Station	1:40 PM	San Diego	La Jolla Village	Economy	$296	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/23/2025 11:15:00 PM to La Jolla Village, San Diego (USA) arriving at 12/25/2025 1:40:00 PM. 50 Economy ticket for $296 per person are available. Travel duration is 40h 25m
Greyhound Lines Mexico	50h 25m	11:20 AM	McAllen, TX	Central Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$322	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/23/2025 11:20:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/25/2025 11:45:00 AM. 50 Economy ticket for $322 per person are available. Travel duration is 50h 25m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	49h 0m	11:15 PM	McAllen, TX	Central Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$272	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/24/2025 11:15:00 PM to Seaport Village, San Diego (USA) arriving at 12/26/2025 10:15:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 49h 0m
FlixBus	40h 55m	11:15 PM	McAllen, TX	Central Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$272	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/24/2025 11:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/26/2025 2:10:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 40h 55m
FlixBus	40h 25m	11:15 PM	McAllen, TX	Central Bus Station	1:40 PM	San Diego	La Jolla Village	Economy	$272	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 12/24/2025 11:15:00 PM to La Jolla Village, San Diego (USA) arriving at 12/26/2025 1:40:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 40h 25m
Greyhound Lines Mexico	50h 25m	11:20 AM	McAllen, TX	Central Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$293	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/24/2025 11:20:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/26/2025 11:45:00 AM. 50 Economy ticket for $293 per person are available. Travel duration is 50h 25m
Greyhound Lines Mexico	48h 20m	11:20 AM	McAllen, TX	Central Bus Station	9:40 AM	San Diego	La Jolla Village	Economy	$293	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 12/24/2025 11:20:00 AM to La Jolla Village, San Diego (USA) arriving at 12/26/2025 9:40:00 AM. 50 Economy ticket for $293 per person are available. Travel duration is 48h 20m

Did you know that if you travel from McAllen, TX to San Diego via Reynosa, you can save more than $44? You can find the corresponding connections below.
- Busbud
  
  48h 10m
  
  0
  
  3:30 PM
  
  McAllen, TX
  Central Bus Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $6
  
  A Bus from Busbud goes from Central Bus Station, McAllen, TX (USA) at 12/19/2025 3:30:00 PM to Hotel City Express, Reynosa (Mexico) arriving at 12/19/2025 5:00:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 30m
- FlixBus
  
  46h 10m
  
  0
  
  5:30 PM
  
  Reynosa
  Central Bus Station
  
  1:40 PM
  
  San Diego
  La Jolla Village
  
  0
  
  Economy
  
  $222
  
  A Bus from FlixBus goes from Central Bus Station, Reynosa (Mexico) at 12/19/2025 5:30:00 PM to La Jolla Village, San Diego (USA) arriving at 12/21/2025 1:40:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 46h 10m
Travel time is 9h 45m longer, but you will save $44

Best Price Offer: The price for the cheapest bus from McAllen, TX to San Diego is $219 on 1/3/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between McAllen, TX and San Diego

See here how frequent the connections between McAllen, TX and San Diego are, during different times and days of the week.

Friday is the busiest day, with more than 9 daily buses from McAllen, TX to San Diego. Monday has instead the fewest connections, with only 1 daily coaches between McAllen, TX and San Diego.

The busiest time of the day is the Evening, with 19 buses from McAllen, TX to San Diego, while Morning sees the fewest connections between McAllen, TX and San Diego, with 13 offers.

Facts about the bus from McAllen, TX to San Diego

Compare all providers like FlixBus and Greyhound Lines Mexico that travel 4 times every day by bus from McAllen, TX to San Diego in one click! Book your bus ticket from McAllen, TX to San Diego starting from $219!

Cheapest Bus	$219
Fastest Bus	38h 25m
Earliest Bus	11:20 AM
Latest Bus	11:15 PM
Daily Bus Routes	4 Ø
Distance	1,222.2 miles
Bus Companies	FlixBus and Greyhound Lines Mexico

Cheapest bus connections from McAllen, TX to San Diego

Every day, 4 buses from 2 bus companies leave McAllen, TX for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$223

Friday 12/19

$220

Saturday 12/20

$226

Sunday 12/21

$235

Monday 12/22

$306

Tuesday 12/23

$225

Wednesday 12/24

$272

Thursday 12/25

$226

Friday 12/26

$300

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

$219

Sunday 01/04

$224

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from McAllen, TX to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from McAllen, TX to San Diego, for the next 30 days.

With a price starting from $219, Saturday is the cheapest day for a bus from McAllen, TX to San Diego. Monday instead is the most expensive day with prices starting from $303.

Evening is the cheapest day time for bus tickets from McAllen, TX to San Diego, with $220. Morning is the most expensive time of the day with prices starting from $243.

How to save money travelling from McAllen, TX to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from McAllen, TX to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from McAllen, TX to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from McAllen, TX to San Diego are also emptier.

All bus stations and stops in McAllen, TX and San Diego

In the map below, you can see where to find all bus stations in McAllen, TX and San Diego.

Central Bus Station

U.S. 83 Business 1501

Frontera México-USA

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from McAllen, TX to San Diego

Want to know which seat classes are available on the buses from McAllen, TX to San Diego? Or which bus companies serve the route McAllen, TX to San Diego? Below you will find answers to your questions.

FAQs about the McAllen, TX to San Diego bus

How much does a McAllen, TX San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $219 and takes 39h 25m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from McAllen, TX to San Diego?

This route is offered by 2 companies with a range of ticket prices between $219 and $485. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from McAllen, TX to San Diego each day?

Every day, the McAllen, TX to San Diego bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from McAllen, TX to San Diego take?

The fastest bus from McAllen, TX to San Diego is offered by FlixBus and takes 38h 25m. Bus tickets for this connection cost $360. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from McAllen, TX to San Diego?

The earliest bus arriving in San Diego from McAllen, TX starts at 11:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from McAllen, TX to San Diego?

The latest bus trip departing from McAllen, TX for San Diego starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the McAllen, TX San Diego route?

When traveling by bus from McAllen, TX to San Diego, passengers can travel with FlixBus and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between McAllen, TX and San Diego?

You can check all the direct connections between McAllen, TX and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound Lines Mexico.

What can I take with me on the McAllen, TX to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the McAllen, TX San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the McAllen, TX San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from McAllen, TX to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from McAllen, TX to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between McAllen, TX and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from McAllen, TX to San Diego?

Prices and availability for 4 trips between McAllen, TX and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route McAllen, TX to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to McAllen, TX and to San Diego

Here’s an overview of the most popular bus routes to McAllen, TX and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!