Bus from Myrtle Beach, SC to Indianapolis from $114

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Compare all timetables for the bus from Myrtle Beach, SC to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Myrtle Beach, SC to Indianapolis from various bus operators like Greyhound US for the next days.

today
tomorrow
$114
Friday
Saturday
$182
Sunday
$131
Monday
Tuesday
$157

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 30m 1:55 PM Myrtle Beach, SC Bus Stop 9:25 PM Indianapolis Washington / Delaware  Economy $114
Greyhound US 22h 10m 1:55 PM Myrtle Beach, SC Bus Stop 12:05 PM Indianapolis Central Bus Station  Economy $114

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 10m 1:55 PM Myrtle Beach, SC Bus Stop 12:05 PM Indianapolis Central Bus Station  Economy $182
Greyhound US 31h 30m 1:55 PM Myrtle Beach, SC Bus Stop 9:25 PM Indianapolis Washington / Delaware  Economy $182
  • Did you know that if you travel from Myrtle Beach, SC to Indianapolis via Atlanta, GA, you can save more than $75? You can find the corresponding connections below.
    • FlixBus
      26h 40m
      0
      1:55 PM
      Myrtle Beach, SC
      Bus Stop
      10:50 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $46
      • Waiting Time 6h 0m
    • Busbud
      11h 45m
      0
      4:50 AM
      Atlanta, GA
      Garnett Transit Station
      4:35 PM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $61
    Travel time is 4h 30m longer, but you will save $75

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 10m 1:55 PM Myrtle Beach, SC Bus Stop 12:05 PM Indianapolis Central Bus Station  Economy $131
Greyhound US 31h 30m 1:55 PM Myrtle Beach, SC Bus Stop 9:25 PM Indianapolis Washington / Delaware  Economy $131
  • Did you know that if you travel from Myrtle Beach, SC to Indianapolis via Atlanta, GA, you can save more than $24? You can find the corresponding connections below.
    • FlixBus
      26h 40m
      0
      1:55 PM
      Myrtle Beach, SC
      Bus Stop
      10:50 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $46
      • Waiting Time 6h 0m
    • Busbud
      11h 45m
      0
      4:50 AM
      Atlanta, GA
      Garnett Transit Station
      4:35 PM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $61
    Travel time is 4h 30m longer, but you will save $24

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 10m 1:55 PM Myrtle Beach, SC Bus Stop 12:05 PM Indianapolis Central Bus Station  Economy $157
  • Did you know that if you travel from Myrtle Beach, SC to Indianapolis via Atlanta, GA, you can save more than $50? You can find the corresponding connections below.
    • FlixBus
      26h 40m
      0
      1:55 PM
      Myrtle Beach, SC
      Bus Stop
      10:50 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $46
      • Waiting Time 6h 0m
    • Busbud
      11h 45m
      0
      4:50 AM
      Atlanta, GA
      Garnett Transit Station
      4:35 PM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $61
    Travel time is 4h 30m longer, but you will save $50

Best Price Offer: The price for the cheapest bus from Myrtle Beach, SC to Indianapolis is $114 on 2/5/2026. Flexible travelers save on ticket prices.


Facts about the bus from Myrtle Beach, SC to Indianapolis

Compare all providers like Greyhound US that travel 1 times every day by bus from Myrtle Beach, SC to Indianapolis in one click! Book your bus ticket from Myrtle Beach, SC to Indianapolis starting from $114!

Cheapest Bus $114
Fastest Bus 22h 10m
Earliest Bus 1:55 PM
Latest Bus 1:55 PM
Daily Bus Routes 1 Ø
Distance 581.4 miles
Bus Companies Greyhound US

Cheapest bus connections from Myrtle Beach, SC to Indianapolis

Every day, 1 buses from 1 bus companies leave Myrtle Beach, SC for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/04/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
$114
Friday 02/06
Saturday 02/07
$182
Sunday 02/08
$131
Monday 02/09
Tuesday 02/10
$157
Wednesday 02/11
Thursday 02/12
Friday 02/13
Saturday 02/14
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

How to save money travelling from Myrtle Beach, SC to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Myrtle Beach, SC to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Myrtle Beach, SC to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Myrtle Beach, SC to Indianapolis are also emptier.

Beloved bus companies from Myrtle Beach, SC to Indianapolis

These are the most booked bus companies between Myrtle Beach, SC to Indianapolis from our users.

Greyhound US from Myrtle Beach, SC to Indianapolis

Greyhound US

Here you will find the key facts about the Greyhound US bus route Myrtle Beach, SC to Indianapolis:

Cheapest Price $114
Fastest Bus 22h 10m
Earliest Bus 1:55 PM
Last Bus 1:55 PM
Daily Connections 1 Ø
Found on 2/1/2026

All bus stations and stops in Myrtle Beach, SC and Indianapolis

In the map below, you can see where to find all bus stations in Myrtle Beach, SC and Indianapolis.

Service and Comfort on the bus from Myrtle Beach, SC to Indianapolis

Want to know which seat classes are available on the buses from Myrtle Beach, SC to Indianapolis? Or which bus companies serve the route Myrtle Beach, SC to Indianapolis? Below you will find answers to your questions.

FAQs about the Myrtle Beach, SC to Indianapolis bus

How much does a Myrtle Beach, SC Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $114 and takes 31h 30m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Myrtle Beach, SC to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $114 and $182. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Myrtle Beach, SC to Indianapolis each day?

Every day, the Myrtle Beach, SC to Indianapolis bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Myrtle Beach, SC to Indianapolis take?

The fastest bus from Myrtle Beach, SC to Indianapolis is offered by Greyhound US and takes 22h 10m. Bus tickets for this connection cost $114. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Myrtle Beach, SC to Indianapolis?

The earliest bus arriving in Indianapolis from Myrtle Beach, SC starts at 1:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Myrtle Beach, SC to Indianapolis?

The latest bus trip departing from Myrtle Beach, SC for Indianapolis starts at 1:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Myrtle Beach, SC Indianapolis route?

When traveling by bus from Myrtle Beach, SC to Indianapolis, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Myrtle Beach, SC and Indianapolis?

You can check all the direct connections between Myrtle Beach, SC and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Myrtle Beach, SC to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Myrtle Beach, SC Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Myrtle Beach, SC Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Myrtle Beach, SC to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from Myrtle Beach, SC to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Myrtle Beach, SC and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Myrtle Beach, SC to Indianapolis?

Prices and availability for 1 trips between Myrtle Beach, SC and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Myrtle Beach, SC to Indianapolis

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Myrtle Beach, SC and to Indianapolis

Here’s an overview of the most popular bus routes to Myrtle Beach, SC and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Myrtle Beach, SC and to Indianapolis
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