Bus from Myrtle Beach, SC to Indianapolis from $105

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Compare all timetables for the bus from Myrtle Beach, SC to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Myrtle Beach, SC to Indianapolis from various bus operators like Greyhound US for the next days.

today
$105
tomorrow
$105
Sunday
Monday
Tuesday
Wednesday
$107
Thursday
$107

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 30m 1:55 PM Myrtle Beach, SC Bus Stop 9:25 PM Indianapolis Washington / Delaware  Economy $105
Greyhound US 22h 10m 1:55 PM Myrtle Beach, SC Bus Stop 12:05 PM Indianapolis Central Bus Station  Economy $107

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 30m 1:55 PM Myrtle Beach, SC Bus Stop 9:25 PM Indianapolis Washington / Delaware  Economy $105
Greyhound US 22h 10m 1:55 PM Myrtle Beach, SC Bus Stop 12:05 PM Indianapolis Central Bus Station  Economy $107

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 30m 1:55 PM Myrtle Beach, SC Bus Stop 9:25 PM Indianapolis Washington / Delaware  Economy $107
Greyhound US 22h 10m 1:55 PM Myrtle Beach, SC Bus Stop 12:05 PM Indianapolis Central Bus Station  Economy $107

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 30m 1:55 PM Myrtle Beach, SC Bus Stop 9:25 PM Indianapolis Washington / Delaware  Economy $107
Greyhound US 22h 10m 1:55 PM Myrtle Beach, SC Bus Stop 12:05 PM Indianapolis Central Bus Station  Economy $107

Best Price Offer: The price for the cheapest bus from Myrtle Beach, SC to Indianapolis is $105 on 12/3/2025. Flexible travelers save on ticket prices.


Facts about the bus from Myrtle Beach, SC to Indianapolis

Compare all providers like Greyhound US that travel 2 times every day by bus from Myrtle Beach, SC to Indianapolis in one click! Book your bus ticket from Myrtle Beach, SC to Indianapolis starting from $105!

Cheapest Bus $105
Fastest Bus 22h 10m
Earliest Bus 1:55 PM
Latest Bus 1:55 PM
Daily Bus Routes 2 Ø
Distance 581.4 miles
Bus Companies Greyhound US

Cheapest bus connections from Myrtle Beach, SC to Indianapolis

Every day, 2 buses from 1 bus companies leave Myrtle Beach, SC for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
Friday 12/05
$105
Saturday 12/06
$105
Sunday 12/07
Monday 12/08
Tuesday 12/09
Wednesday 12/10
$107
Thursday 12/11
$107
Friday 12/12
Saturday 12/13
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27

How to save money travelling from Myrtle Beach, SC to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Myrtle Beach, SC to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Myrtle Beach, SC to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Myrtle Beach, SC to Indianapolis are also emptier.

Beloved bus companies from Myrtle Beach, SC to Indianapolis

These are the most booked bus companies between Myrtle Beach, SC to Indianapolis from our users.

Greyhound US from Myrtle Beach, SC to Indianapolis

Greyhound US

Here you will find the key facts about the Greyhound US bus route Myrtle Beach, SC to Indianapolis:

Cheapest Price $105
Fastest Bus 22h 10m
Earliest Bus 1:55 PM
Last Bus 1:55 PM
Daily Connections 2 Ø
Found on 12/3/2025

All bus stations and stops in Myrtle Beach, SC and Indianapolis

In the map below, you can see where to find all bus stations in Myrtle Beach, SC and Indianapolis.

Service and Comfort on the bus from Myrtle Beach, SC to Indianapolis

Want to know which seat classes are available on the buses from Myrtle Beach, SC to Indianapolis? Or which bus companies serve the route Myrtle Beach, SC to Indianapolis? Below you will find answers to your questions.

FAQs about the Myrtle Beach, SC to Indianapolis bus

How much does a Myrtle Beach, SC Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $105 and takes 31h 30m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Myrtle Beach, SC to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $105 and $107. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Myrtle Beach, SC to Indianapolis each day?

Every day, the Myrtle Beach, SC to Indianapolis bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Myrtle Beach, SC to Indianapolis take?

The fastest bus from Myrtle Beach, SC to Indianapolis is offered by Greyhound US and takes 22h 10m. Bus tickets for this connection cost $107. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Myrtle Beach, SC to Indianapolis?

The earliest bus arriving in Indianapolis from Myrtle Beach, SC starts at 1:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Myrtle Beach, SC to Indianapolis?

The latest bus trip departing from Myrtle Beach, SC for Indianapolis starts at 1:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Myrtle Beach, SC Indianapolis route?

When traveling by bus from Myrtle Beach, SC to Indianapolis, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Myrtle Beach, SC and Indianapolis?

You can check all the direct connections between Myrtle Beach, SC and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Myrtle Beach, SC to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Myrtle Beach, SC Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Myrtle Beach, SC Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Myrtle Beach, SC to Indianapolis on your planned travel date.

Available seat classes which are offered on the bus route Myrtle Beach, SC to Indianapolis

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Myrtle Beach, SC and to Indianapolis

Here’s an overview of the most popular bus routes to Myrtle Beach, SC and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
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