Bus Panama City Beach, FL to Chicago: Compare prices and save money

Compare all timetables for the bus from Panama City Beach, FL to Chicago

Here is a selection of the cheapest bus trips from the schedule from Panama City Beach, FL to Chicago from various bus operators like Greyhound US for the next days.

today

tomorrow

Wednesday

$106

Thursday

$110

Friday

Saturday

$113

Sunday

$102

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 35m	7:30 AM	Panama City Beach, FL	Parkway	11:05 AM	Chicago	95th Red Line Station	Economy	$106	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/22/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 4/23/2026 11:05:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 35m
Greyhound US	31h 40m	9:40 PM	Panama City Beach, FL	Parkway	5:20 AM	Chicago	95th Red Line Station	Economy	$106	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/22/2026 9:40:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/24/2026 5:20:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 31h 40m
Greyhound US	29h 45m	12:50 PM	Panama City Beach, FL	Parkway	6:35 PM	Chicago	95th Red Line Station	Economy	$107	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/22/2026 12:50:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/23/2026 6:35:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 29h 45m
Greyhound US	33h 35m	2:15 PM	Panama City Beach, FL	Parkway	11:50 PM	Chicago	95th Red Line Station	Economy	$107	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/22/2026 2:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/23/2026 11:50:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 33h 35m
Greyhound US	34h 20m	9:40 PM	Panama City Beach, FL	Parkway	8:00 AM	Chicago	Canal & Van Buren	Economy	$118	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/22/2026 9:40:00 PM to Canal & Van Buren, Chicago (USA) arriving at 4/24/2026 8:00:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 34h 20m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 35m	2:15 PM	Panama City Beach, FL	Parkway	11:50 PM	Chicago	95th Red Line Station	Economy	$110	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/23/2026 2:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/24/2026 11:50:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 33h 35m
Greyhound US	27h 35m	7:30 AM	Panama City Beach, FL	Parkway	11:05 AM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/23/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 4/24/2026 11:05:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 27h 35m
Greyhound US	29h 45m	12:50 PM	Panama City Beach, FL	Parkway	6:35 PM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/23/2026 12:50:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/24/2026 6:35:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 29h 45m
Greyhound US	31h 40m	9:40 PM	Panama City Beach, FL	Parkway	5:20 AM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/23/2026 9:40:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/25/2026 5:20:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 31h 40m
Greyhound US	34h 20m	9:40 PM	Panama City Beach, FL	Parkway	8:00 AM	Chicago	Canal & Van Buren	Economy	$118	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/23/2026 9:40:00 PM to Canal & Van Buren, Chicago (USA) arriving at 4/25/2026 8:00:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 34h 20m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 35m	7:30 AM	Panama City Beach, FL	Parkway	11:05 AM	Chicago	95th Red Line Station	Economy	$113	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/25/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 4/26/2026 11:05:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 27h 35m
Greyhound US	29h 45m	12:50 PM	Panama City Beach, FL	Parkway	6:35 PM	Chicago	95th Red Line Station	Economy	$113	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/25/2026 12:50:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/26/2026 6:35:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 29h 45m
Greyhound US	31h 40m	9:40 PM	Panama City Beach, FL	Parkway	5:20 AM	Chicago	95th Red Line Station	Economy	$113	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/25/2026 9:40:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/27/2026 5:20:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 31h 40m
Greyhound US	33h 35m	2:15 PM	Panama City Beach, FL	Parkway	11:50 PM	Chicago	95th Red Line Station	Economy	$114	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/25/2026 2:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/26/2026 11:50:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 33h 35m
Greyhound US	30h 40m	9:40 PM	Panama City Beach, FL	Parkway	4:20 AM	Chicago	Downtown Bus Station	Economy	$129	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/25/2026 9:40:00 PM to Downtown Bus Station, Chicago (USA) arriving at 4/27/2026 4:20:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 30h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 35m	2:15 PM	Panama City Beach, FL	Parkway	11:50 PM	Chicago	95th Red Line Station	Economy	$102	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/26/2026 2:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/27/2026 11:50:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 33h 35m
Greyhound US	27h 35m	7:30 AM	Panama City Beach, FL	Parkway	11:05 AM	Chicago	95th Red Line Station	Economy	$103	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/26/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 4/27/2026 11:05:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 27h 35m
Greyhound US	29h 45m	12:50 PM	Panama City Beach, FL	Parkway	6:35 PM	Chicago	95th Red Line Station	Economy	$104	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/26/2026 12:50:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/27/2026 6:35:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 29h 45m
Greyhound US	31h 40m	9:40 PM	Panama City Beach, FL	Parkway	5:20 AM	Chicago	95th Red Line Station	Economy	$104	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/26/2026 9:40:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/28/2026 5:20:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 31h 40m
Greyhound US	30h 40m	7:30 AM	Panama City Beach, FL	Parkway	2:10 PM	Chicago	Canal & Van Buren	Economy	$123	A Bus from Greyhound US goes from Parkway, Panama City Beach, FL (USA) at 4/26/2026 7:30:00 AM to Canal & Van Buren, Chicago (USA) arriving at 4/27/2026 2:10:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 30h 40m

Best Price Offer: The price for the cheapest bus from Panama City Beach, FL to Chicago is $94 on 5/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Panama City Beach, FL and Chicago

See here how frequent the connections between Panama City Beach, FL and Chicago are, during different times and days of the week.

Sunday is the busiest day, with more than 10 daily buses from Panama City Beach, FL to Chicago. Sunday has instead the fewest connections, with only 10 daily coaches between Panama City Beach, FL and Chicago.

The busiest time of the day is the Afternoon, with 16 buses from Panama City Beach, FL to Chicago, while Morning sees the fewest connections between Panama City Beach, FL and Chicago, with 12 offers.

Facts about the bus from Panama City Beach, FL to Chicago

Compare all providers like Greyhound US that travel 10 times every day by bus from Panama City Beach, FL to Chicago in one click! Book your bus ticket from Panama City Beach, FL to Chicago starting from $94!

Cheapest Bus	$94
Fastest Bus	26h 25m
Earliest Bus	7:30 AM
Latest Bus	9:40 PM
Daily Bus Routes	10 Ø
Distance	815.1 miles
Bus Companies	Greyhound US

Cheapest bus connections from Panama City Beach, FL to Chicago

Every day, 10 buses from 1 bus companies leave Panama City Beach, FL for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

Tuesday 04/21

Wednesday 04/22

$106

Thursday 04/23

$110

Friday 04/24

Saturday 04/25

$113

Sunday 04/26

$102

Monday 04/27

Tuesday 04/28

Wednesday 04/29

$101

Thursday 04/30

Friday 05/01

Saturday 05/02

Sunday 05/03

$117

Monday 05/04

$105

Tuesday 05/05

$106

Wednesday 05/06

Thursday 05/07

Friday 05/08

$103

Saturday 05/09

Sunday 05/10

$107

Monday 05/11

$104

Tuesday 05/12

$104

Wednesday 05/13

$99

Thursday 05/14

$94

Friday 05/15

$96

Saturday 05/16

The cheapest time to travel from Panama City Beach, FL to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Panama City Beach, FL to Chicago, for the next 30 days.

With a price starting from $94, Thursday is the cheapest day for a bus from Panama City Beach, FL to Chicago. Saturday instead is the most expensive day with prices starting from $103.

Afternoon is the cheapest day time for bus tickets from Panama City Beach, FL to Chicago, with $102. Evening is the most expensive time of the day with prices starting from $104.

How to save money travelling from Panama City Beach, FL to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Panama City Beach, FL to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Panama City Beach, FL to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Panama City Beach, FL to Chicago are also emptier.

All bus stations and stops in Panama City Beach, FL and Chicago

In the map below, you can see where to find all bus stations in Panama City Beach, FL and Chicago.

Parkway

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Panama City Beach, FL to Chicago

Want to know which seat classes are available on the buses from Panama City Beach, FL to Chicago? Or which bus companies serve the route Panama City Beach, FL to Chicago? Below you will find answers to your questions.

FAQs about the Panama City Beach, FL to Chicago bus

How much does a Panama City Beach, FL Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $94 and takes 33h 35m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Panama City Beach, FL to Chicago?

This route is offered by 1 companies with a range of ticket prices between $94 and $131. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Panama City Beach, FL to Chicago each day?

Every day, the Panama City Beach, FL to Chicago bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Panama City Beach, FL to Chicago take?

The fastest bus from Panama City Beach, FL to Chicago is offered by Greyhound US and takes 26h 25m. Bus tickets for this connection cost $119. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Panama City Beach, FL to Chicago?

The earliest bus arriving in Chicago from Panama City Beach, FL starts at 7:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Panama City Beach, FL to Chicago?

The latest bus trip departing from Panama City Beach, FL for Chicago starts at 9:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Panama City Beach, FL Chicago route?

When traveling by bus from Panama City Beach, FL to Chicago, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Panama City Beach, FL and Chicago?

You can check all the direct connections between Panama City Beach, FL and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Panama City Beach, FL to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Panama City Beach, FL Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Panama City Beach, FL Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Panama City Beach, FL to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Panama City Beach, FL to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Panama City Beach, FL and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Panama City Beach, FL to Chicago?

Prices and availability for 10 trips between Panama City Beach, FL and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Panama City Beach, FL to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Panama City Beach, FL and to Chicago

Here’s an overview of the most popular bus routes to Panama City Beach, FL and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!