Bus from Pittsburgh to Chicago from $50

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Pittsburgh to Chicago

Here is a selection of the cheapest bus trips from the schedule from Pittsburgh to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today
$50
tomorrow
$51
Thursday
$56
Friday
$60
Saturday
$57
Sunday
$68
Monday
$54

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 12h 30m 8:35 AM Pittsburgh Grant Street Transportation Center 8:05 PM Chicago Downtown Bus Station  Economy $50
Greyhound US 10h 5m 12:55 AM Pittsburgh Grant Street Transportation Center 10:00 AM Chicago Downtown Bus Station  Economy $55
FlixBus 11h 25m 7:45 PM Pittsburgh Grant Street Transportation Center 6:10 AM Chicago Downtown Bus Station  Economy $58
Greyhound US 14h 0m 1:35 AM Pittsburgh Grant Street Transportation Center 2:35 PM Chicago Downtown Bus Station  Economy $63
FlixBus 10h 55m 7:45 PM Pittsburgh Grant Street Transportation Center 5:40 AM Chicago 95th Red Line Station  Economy $63

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 10h 55m 7:45 PM Pittsburgh Grant Street Transportation Center 5:40 AM Chicago 95th Red Line Station  Economy $51
Greyhound US 13h 30m 12:55 AM Pittsburgh Grant Street Transportation Center 1:25 PM Chicago 95th Red Line Station  Economy $88
Greyhound US 13h 5m 1:35 AM Pittsburgh Grant Street Transportation Center 1:40 PM Chicago 95th Red Line Station  Economy $88
Greyhound US 14h 50m 8:00 PM Pittsburgh Grant Street Transportation Center 9:50 AM Chicago 95th Red Line Station  Economy $88

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 10h 5m 12:55 AM Pittsburgh Grant Street Transportation Center 10:00 AM Chicago Downtown Bus Station  Economy $56
Greyhound US 12h 30m 8:35 AM Pittsburgh Grant Street Transportation Center 8:05 PM Chicago Downtown Bus Station  Economy $56
FlixBus 11h 25m 7:45 PM Pittsburgh Grant Street Transportation Center 6:10 AM Chicago Downtown Bus Station  Economy $61
FlixBus 10h 55m 7:45 PM Pittsburgh Grant Street Transportation Center 5:40 AM Chicago 95th Red Line Station  Economy $66
Greyhound US 14h 15m 1:20 AM Pittsburgh Grant Street Transportation Center 2:35 PM Chicago Downtown Bus Station  Economy $68

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 10h 5m 12:55 AM Pittsburgh Grant Street Transportation Center 10:00 AM Chicago Downtown Bus Station  Economy $60
FlixBus 11h 25m 7:45 PM Pittsburgh Grant Street Transportation Center 6:10 AM Chicago Downtown Bus Station  Economy $66
Greyhound US 12h 30m 8:35 AM Pittsburgh Grant Street Transportation Center 8:05 PM Chicago Downtown Bus Station  Economy $70
FlixBus 10h 55m 7:45 PM Pittsburgh Grant Street Transportation Center 5:40 AM Chicago 95th Red Line Station  Economy $72
Greyhound US 14h 15m 1:20 AM Pittsburgh Grant Street Transportation Center 2:35 PM Chicago Downtown Bus Station  Economy $77

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 12h 30m 8:35 AM Pittsburgh Grant Street Transportation Center 8:05 PM Chicago Downtown Bus Station  Economy $57
Greyhound US 10h 5m 12:55 AM Pittsburgh Grant Street Transportation Center 10:00 AM Chicago Downtown Bus Station  Economy $58
FlixBus 11h 25m 7:45 PM Pittsburgh Grant Street Transportation Center 6:10 AM Chicago Downtown Bus Station  Economy $62
FlixBus 10h 55m 7:45 PM Pittsburgh Grant Street Transportation Center 5:40 AM Chicago 95th Red Line Station  Economy $67
Greyhound US 14h 15m 1:20 AM Pittsburgh Grant Street Transportation Center 2:35 PM Chicago Downtown Bus Station  Economy $68

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 10h 5m 12:55 AM Pittsburgh Grant Street Transportation Center 10:00 AM Chicago Downtown Bus Station  Economy $68
Greyhound US 12h 30m 8:35 AM Pittsburgh Grant Street Transportation Center 8:05 PM Chicago Downtown Bus Station  Economy $68
Greyhound US 14h 15m 1:20 AM Pittsburgh Grant Street Transportation Center 2:35 PM Chicago Downtown Bus Station  Economy $70
FlixBus 11h 25m 7:45 PM Pittsburgh Grant Street Transportation Center 6:10 AM Chicago Downtown Bus Station  Economy $74
  • Did you know that if you travel from Pittsburgh to Chicago via Cleveland, you can save more than $12? You can find the corresponding connections below.
    • Greyhound US
      12h 15m
      0
      8:50 AM
      Pittsburgh
      Grant Street Transportation Center
      11:25 AM
      Cleveland
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $18
      • Waiting Time 0h 10m
    • Greyhound US
      9h 30m
      0
      11:35 AM
      Cleveland
      Greyhound Bus Station
      8:05 PM
      Chicago
      Downtown Bus Station
      0
      Greyhound US
      Economy
      $38
    Travel time is 3h 10m longer, but you will save $12

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 12h 30m 8:35 AM Pittsburgh Grant Street Transportation Center 8:05 PM Chicago Downtown Bus Station  Economy $54
Greyhound US 10h 5m 12:55 AM Pittsburgh Grant Street Transportation Center 10:00 AM Chicago Downtown Bus Station  Economy $56
FlixBus 11h 25m 7:45 PM Pittsburgh Grant Street Transportation Center 6:10 AM Chicago Downtown Bus Station  Economy $59
Greyhound US 12h 15m 8:50 AM Pittsburgh Grant Street Transportation Center 8:05 PM Chicago Downtown Bus Station  Economy $64
FlixBus 10h 55m 7:45 PM Pittsburgh Grant Street Transportation Center 5:40 AM Chicago 95th Red Line Station  Economy $66

Best Price Offer: The price for the cheapest bus from Pittsburgh to Chicago is $50 on 3/24/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Pittsburgh and Chicago

See here how frequent the connections between Pittsburgh and Chicago are, during different times and days of the week.
Thursday is the busiest day, with more than 30 daily buses from Pittsburgh to Chicago. Wednesday has instead the fewest connections, with only 5 daily coaches between Pittsburgh and Chicago.
The busiest time of the day is the Night, with 65 buses from Pittsburgh to Chicago, while Morning sees the fewest connections between Pittsburgh and Chicago, with 30 offers.

Facts about the bus from Pittsburgh to Chicago

Compare all providers like Greyhound US and FlixBus that travel 20 times every day by bus from Pittsburgh to Chicago in one click! Book your bus ticket from Pittsburgh to Chicago starting from $50!

Cheapest Bus $50
Fastest Bus 9h 5m
Earliest Bus 12:55 AM
Latest Bus 8:00 PM
Daily Bus Routes 20 Ø
Distance 409.7 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Pittsburgh to Chicago

Every day, 20 buses from 2 bus companies leave Pittsburgh for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/24/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/22
Monday 03/23
Tuesday 03/24
$50
Wednesday 03/25
$51
Thursday 03/26
$56
Friday 03/27
$60
Saturday 03/28
$57
Sunday 03/29
$68
Monday 03/30
$54
Tuesday 03/31
$56
Wednesday 04/01
$58
Thursday 04/02
$54
Friday 04/03
$57
Saturday 04/04
$59
Sunday 04/05
$76
Monday 04/06
$56
Tuesday 04/07
$57
Wednesday 04/08
$56
Thursday 04/09
$55
Friday 04/10
$57
Saturday 04/11
$60
Sunday 04/12
$62
Monday 04/13
$55
Tuesday 04/14
$57
Wednesday 04/15
$53
Thursday 04/16
$57
Friday 04/17
$64
Saturday 04/18

The cheapest time to travel from Pittsburgh to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Pittsburgh to Chicago, for the next 30 days.
With a price starting from $50, Tuesday is the cheapest day for a bus from Pittsburgh to Chicago. Sunday instead is the most expensive day with prices starting from $58.
Morning is the cheapest day time for bus tickets from Pittsburgh to Chicago, with $50. Evening is the most expensive time of the day with prices starting from $51.

How to save money travelling from Pittsburgh to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pittsburgh to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pittsburgh to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Pittsburgh to Chicago are also emptier.

Beloved bus companies from Pittsburgh to Chicago

These are the most booked bus companies between Pittsburgh to Chicago from our users.

Greyhound US from Pittsburgh to Chicago

Greyhound US

Here you will find the key facts about the Greyhound US bus route Pittsburgh to Chicago:

Cheapest Price $50
Fastest Bus 9h 5m
Earliest Bus 12:55 AM
Last Bus 8:00 PM
Daily Connections 17 Ø
Found on 3/15/2026

FlixBus from Pittsburgh to Chicago

FlixBus

Here you will find the key facts about the FlixBus bus route Pittsburgh to Chicago:

Cheapest Price $51
Fastest Bus 9h 55m
Earliest Bus 7:45 PM
Last Bus 7:45 PM
Daily Connections 2 Ø
Found on 3/15/2026

All bus stations and stops in Pittsburgh and Chicago

In the map below, you can see where to find all bus stations in Pittsburgh and Chicago.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Pittsburgh to Chicago? Compare all modes of transports from Pittsburgh to Chicago.

Service and Comfort on the bus from Pittsburgh to Chicago

Want to know which seat classes are available on the buses from Pittsburgh to Chicago? Or which bus companies serve the route Pittsburgh to Chicago? Below you will find answers to your questions.

FAQs about the Pittsburgh to Chicago bus

How much does a Pittsburgh Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $50 and takes 11h 30m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Pittsburgh to Chicago?

This route is offered by 2 companies with a range of ticket prices between $50 and $107. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Pittsburgh to Chicago each day?

Every day, the Pittsburgh to Chicago bus route is served by approximately 20 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Pittsburgh to Chicago take?

The fastest bus from Pittsburgh to Chicago is offered by Greyhound US and takes 9h 5m. Bus tickets for this connection cost $55. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Pittsburgh to Chicago?

The earliest bus arriving in Chicago from Pittsburgh starts at 12:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Pittsburgh to Chicago?

The latest bus trip departing from Pittsburgh for Chicago starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Pittsburgh Chicago route?

When traveling by bus from Pittsburgh to Chicago, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Pittsburgh and Chicago?

You can check all the direct connections between Pittsburgh and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Pittsburgh to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Pittsburgh Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Pittsburgh Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pittsburgh to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Pittsburgh to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 20 daily trips between Pittsburgh and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Pittsburgh to Chicago?

Prices and availability for 20 trips between Pittsburgh and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Pittsburgh to Chicago

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pittsburgh and to Chicago

Here’s an overview of the most popular bus routes to Pittsburgh and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Pittsburgh from Las Cruces, NM Bus to Pittsburgh from Las Cruces, NM
Buses from Clarksville, TN to Pittsburgh Buses from Clarksville, TN to Pittsburgh
Buses from Woodbridge, VA to Pittsburgh Buses from Woodbridge, VA to Pittsburgh
Buses to Pittsburgh from Silver Spring, MD Buses to Pittsburgh from Silver Spring, MD
Birmingham, AL to Chicago bus Birmingham, AL to Chicago bus
Buses to Chicago from Eau Claire, WI Buses to Chicago from Eau Claire, WI
From New Orleans, LA to Chicago bus From New Orleans, LA to Chicago bus
From Austin to Chicago bus From Austin to Chicago bus
Popular Airport Shuttles to Pittsburgh and to Chicago
CheckMyBus › Buses in USA › Bus to Pittsburgh › Bus to Chicago

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.