Bus Pittsburgh to Chicago: Compare prices and save money

Compare all timetables for the bus from Pittsburgh to Chicago

Here is a selection of the cheapest bus trips from the schedule from Pittsburgh to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today

$103

tomorrow

$81

Friday

Saturday

Sunday

$86

Monday

$74

Tuesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 55m	7:45 PM	Pittsburgh	Grant Street Transportation Center	5:40 AM	Chicago	95th Red Line Station	Economy	$103	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/24/2025 7:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/25/2025 5:40:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 10h 55m
FlixBus	11h 25m	7:45 PM	Pittsburgh	Grant Street Transportation Center	6:10 AM	Chicago	Downtown Bus Station	Economy	$107	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/24/2025 7:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/25/2025 6:10:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 11h 25m
Greyhound US	13h 45m	12:40 AM	Pittsburgh	Grant Street Transportation Center	1:25 PM	Chicago	95th Red Line Station	Economy	$123	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/24/2025 12:40:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/24/2025 1:25:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 13h 45m
Greyhound US	14h 50m	8:00 PM	Pittsburgh	Grant Street Transportation Center	9:50 AM	Chicago	95th Red Line Station	Economy	$125	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/24/2025 8:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/25/2025 9:50:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 14h 50m
Greyhound US	12h 25m	8:40 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$126	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/24/2025 8:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/24/2025 8:05:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 12h 25m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 25m	7:40 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$81	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/25/2025 7:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/25/2025 8:05:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 13h 25m
Greyhound US	14h 0m	1:35 AM	Pittsburgh	Grant Street Transportation Center	2:35 PM	Chicago	Downtown Bus Station	Economy	$83	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/25/2025 1:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/25/2025 2:35:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 14h 0m
Greyhound US	12h 25m	8:40 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$83	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/25/2025 8:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/25/2025 8:05:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 12h 25m
FlixBus	11h 25m	7:45 PM	Pittsburgh	Grant Street Transportation Center	6:10 AM	Chicago	Downtown Bus Station	Economy	$92	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/25/2025 7:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/26/2025 6:10:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 11h 25m
FlixBus	10h 55m	7:45 PM	Pittsburgh	Grant Street Transportation Center	5:40 AM	Chicago	95th Red Line Station	Economy	$100	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/25/2025 7:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/26/2025 5:40:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 10h 55m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 25m	7:40 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$86	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/28/2025 7:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/28/2025 8:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 13h 25m
Greyhound US	10h 20m	12:40 AM	Pittsburgh	Grant Street Transportation Center	10:00 AM	Chicago	Downtown Bus Station	Economy	$93	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/28/2025 12:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/28/2025 10:00:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 10h 20m
Greyhound US	12h 25m	8:40 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$100	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/28/2025 8:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/28/2025 8:05:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 12h 25m
FlixBus	10h 55m	7:45 PM	Pittsburgh	Grant Street Transportation Center	5:40 AM	Chicago	95th Red Line Station	Economy	$101	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/28/2025 7:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/29/2025 5:40:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 10h 55m
FlixBus	11h 25m	7:45 PM	Pittsburgh	Grant Street Transportation Center	6:10 AM	Chicago	Downtown Bus Station	Economy	$102	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/28/2025 7:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/29/2025 6:10:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 11h 25m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 25m	7:40 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$74	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/29/2025 7:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/29/2025 8:05:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 13h 25m
Greyhound US	12h 25m	8:40 AM	Pittsburgh	Grant Street Transportation Center	8:05 PM	Chicago	Downtown Bus Station	Economy	$81	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/29/2025 8:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/29/2025 8:05:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 12h 25m
Greyhound US	10h 20m	12:40 AM	Pittsburgh	Grant Street Transportation Center	10:00 AM	Chicago	Downtown Bus Station	Economy	$86	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/29/2025 12:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/29/2025 10:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 10h 20m
FlixBus	11h 25m	7:45 PM	Pittsburgh	Grant Street Transportation Center	6:10 AM	Chicago	Downtown Bus Station	Economy	$86	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/29/2025 7:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/30/2025 6:10:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 11h 25m
FlixBus	10h 55m	7:45 PM	Pittsburgh	Grant Street Transportation Center	5:40 AM	Chicago	95th Red Line Station	Economy	$98	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/29/2025 7:45:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/30/2025 5:40:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 10h 55m

Best Price Offer: The price for the cheapest bus from Pittsburgh to Chicago is $51 on 1/12/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Pittsburgh and Chicago

See here how frequent the connections between Pittsburgh and Chicago are, during different times and days of the week.

Wednesday is the busiest day, with more than 28 daily buses from Pittsburgh to Chicago. Monday has instead the fewest connections, with only 13 daily coaches between Pittsburgh and Chicago.

The busiest time of the day is the Night, with 30 buses from Pittsburgh to Chicago, while Morning sees the fewest connections between Pittsburgh and Chicago, with 24 offers.

Facts about the bus from Pittsburgh to Chicago

Compare all providers like Greyhound US and FlixBus that travel 20 times every day by bus from Pittsburgh to Chicago in one click! Book your bus ticket from Pittsburgh to Chicago starting from $51!

Cheapest Bus	$51
Fastest Bus	9h 20m
Earliest Bus	12:40 AM
Latest Bus	8:00 PM
Daily Bus Routes	20 Ø
Distance	409.7 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Pittsburgh to Chicago

Every day, 20 buses from 2 bus companies leave Pittsburgh for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/24/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$103

Thursday 12/25

$81

Friday 12/26

Saturday 12/27

Sunday 12/28

$101

Monday 12/29

$95

Tuesday 12/30

Wednesday 12/31

$81

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

$57

Friday 01/09

$56

Saturday 01/10

$60

Sunday 01/11

Monday 01/12

$51

Tuesday 01/13

Wednesday 01/14

Thursday 01/15

$52

Friday 01/16

Saturday 01/17

The cheapest time to travel from Pittsburgh to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Pittsburgh to Chicago, for the next 30 days.

With a price starting from $51, Monday is the cheapest day for a bus from Pittsburgh to Chicago. Sunday instead is the most expensive day with prices starting from $86.

Night is the cheapest day time for bus tickets from Pittsburgh to Chicago, with $51. Evening is the most expensive time of the day with prices starting from $86.

How to save money travelling from Pittsburgh to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pittsburgh to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pittsburgh to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Pittsburgh to Chicago are also emptier.

Beloved bus companies from Pittsburgh to Chicago

These are the most booked bus companies between Pittsburgh to Chicago from our users.

Greyhound US from Pittsburgh to Chicago

Here you will find the key facts about the Greyhound US bus route Pittsburgh to Chicago:

Cheapest Price	$74
Fastest Bus	9h 20m
Earliest Bus	12:40 AM
Last Bus	8:00 PM
Daily Connections	17 Ø
Found on	12/24/2025

All bus stations and stops in Pittsburgh and Chicago

In the map below, you can see where to find all bus stations in Pittsburgh and Chicago.

Grant Street Transportation Center

11th St 55

David L. Lawrence Convention Center

10th St Pittsburgh 131-199

Carnegie Mellon

Forbes Ave

University of

Bus Stop

Forbes Ave 3501

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Pittsburgh to Chicago? Compare all modes of transports from Pittsburgh to Chicago.

Service and Comfort on the bus from Pittsburgh to Chicago

Want to know which seat classes are available on the buses from Pittsburgh to Chicago? Or which bus companies serve the route Pittsburgh to Chicago? Below you will find answers to your questions.

FAQs about the Pittsburgh to Chicago bus

How much does a Pittsburgh Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $51 and takes 12h 25m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Pittsburgh to Chicago?

This route is offered by 2 companies with a range of ticket prices between $51 and $151. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Pittsburgh to Chicago each day?

Every day, the Pittsburgh to Chicago bus route is served by approximately 20 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Pittsburgh to Chicago take?

The fastest bus from Pittsburgh to Chicago is offered by Greyhound US and takes 9h 20m. Bus tickets for this connection cost $133. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Pittsburgh to Chicago?

The earliest bus arriving in Chicago from Pittsburgh starts at 12:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Pittsburgh to Chicago?

The latest bus trip departing from Pittsburgh for Chicago starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Pittsburgh Chicago route?

When traveling by bus from Pittsburgh to Chicago, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Pittsburgh and Chicago?

You can check all the direct connections between Pittsburgh and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Pittsburgh to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Pittsburgh Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Pittsburgh Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pittsburgh to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Pittsburgh to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 20 daily trips between Pittsburgh and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Pittsburgh to Chicago?

Prices and availability for 20 trips between Pittsburgh and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Pittsburgh to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pittsburgh and to Chicago

Here’s an overview of the most popular bus routes to Pittsburgh and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!