Bus Santa Ana, CA to Portland, OR: Compare prices and save money

Compare all timetables for the bus from Santa Ana, CA to Portland, OR

Here is a selection of the cheapest bus trips from the schedule from Santa Ana, CA to Portland, OR from various bus operators like Greyhound US for the next days.

today

$168

tomorrow

$144

Sunday

$150

Monday

$126

Tuesday

Wednesday

$133

Thursday

$150

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 5m	7:40 AM	Santa Ana, CA	Bus Stop	8:45 AM	Portland, OR	Greyhound Bus Station		Economy	$168	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/16/2026 7:40:00 AM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/17/2026 8:45:00 AM. 50 Economy ticket for $168 per person are available. Travel duration is 25h 5m
	Greyhound US	28h 5m	9:25 PM	Santa Ana, CA	Bus Stop	1:30 AM	Portland, OR	Greyhound Bus Station		Economy	$189	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/16/2026 9:25:00 PM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/18/2026 1:30:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 28h 5m

Did you know that if you travel from Santa Ana, CA to Portland, OR via Los Angeles, you can save more than $33? You can find the corresponding connections below.
- Greyhound US
  
  28h 5m
  
  0
  
  9:25 PM
  
  Santa Ana, CA
  Bus Stop
  
  10:20 PM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $5
  
  A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/17/2026 9:25:00 PM to Union Station, Los Angeles (USA) arriving at 10/17/2026 10:20:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 55m
- Greyhound US
  
  25h 40m
  
  0
  
  11:50 PM
  
  Los Angeles
  Union Station
  
  1:30 AM
  
  Portland, OR
  Greyhound Bus Station
  
  0
  
  Economy
  
  $130
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 10/17/2026 11:50:00 PM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/19/2026 1:30:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 25h 40m
Travel time is 3h 0m longer, but you will save $33

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 5m	7:40 AM	Santa Ana, CA	Bus Stop	8:45 AM	Portland, OR	Greyhound Bus Station		Economy	$144	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/17/2026 7:40:00 AM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/18/2026 8:45:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 25h 5m
	Greyhound US	28h 5m	9:25 PM	Santa Ana, CA	Bus Stop	1:30 AM	Portland, OR	Greyhound Bus Station		Economy	$162	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/17/2026 9:25:00 PM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/19/2026 1:30:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 28h 5m

Did you know that if you travel from Santa Ana, CA to Portland, OR via Los Angeles, you can save more than $25? You can find the corresponding connections below.
- Greyhound US
  
  37h 15m
  
  0
  
  7:30 PM
  
  Santa Ana, CA
  Bus Stop
  
  9:15 PM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/18/2026 7:30:00 PM to Union Station, Los Angeles (USA) arriving at 10/18/2026 9:15:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 45m
- FlixBus
  
  25h 10m
  
  0
  
  7:35 AM
  
  Los Angeles
  North Hollywood
  
  8:45 AM
  
  Portland, OR
  Greyhound Bus Station
  
  0
  
  Economy
  
  $112
  
  A Bus from FlixBus goes from North Hollywood, Los Angeles (USA) at 10/19/2026 7:35:00 AM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/20/2026 8:45:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 25h 10m
Travel time is 12h 10m longer, but you will save $25

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 5m	7:40 AM	Santa Ana, CA	Bus Stop	8:45 AM	Portland, OR	Greyhound Bus Station		Economy	$150	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/18/2026 7:40:00 AM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/19/2026 8:45:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 25h 5m
	Greyhound US	28h 5m	9:25 PM	Santa Ana, CA	Bus Stop	1:30 AM	Portland, OR	Greyhound Bus Station		Economy	$178	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/18/2026 9:25:00 PM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/20/2026 1:30:00 AM. 50 Economy ticket for $178 per person are available. Travel duration is 28h 5m

Did you know that if you travel from Santa Ana, CA to Portland, OR via Los Angeles, you can save more than $50? You can find the corresponding connections below.
- Greyhound US
  
  35h 20m
  
  0
  
  9:25 PM
  
  Santa Ana, CA
  Bus Stop
  
  10:20 PM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $5
  
  A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/19/2026 9:25:00 PM to Union Station, Los Angeles (USA) arriving at 10/19/2026 10:20:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 55m
- FlixBus
  
  25h 10m
  
  0
  
  7:35 AM
  
  Los Angeles
  North Hollywood
  
  8:45 AM
  
  Portland, OR
  Greyhound Bus Station
  
  0
  
  Economy
  
  $95
  
  A Bus from FlixBus goes from North Hollywood, Los Angeles (USA) at 10/20/2026 7:35:00 AM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/21/2026 8:45:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 25h 10m
Travel time is 10h 15m longer, but you will save $50

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 5m	7:40 AM	Santa Ana, CA	Bus Stop	8:45 AM	Portland, OR	Union Bus Station		Economy	$126	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/19/2026 7:40:00 AM to Union Bus Station, Portland, OR (USA) arriving at 10/20/2026 8:45:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 25h 5m
	Greyhound US	28h 5m	9:25 PM	Santa Ana, CA	Bus Stop	1:30 AM	Portland, OR	Union Bus Station		Economy	$134	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/19/2026 9:25:00 PM to Union Bus Station, Portland, OR (USA) arriving at 10/21/2026 1:30:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 28h 5m

Did you know that if you travel from Santa Ana, CA to Portland, OR via Los Angeles, you can save more than $26? You can find the corresponding connections below.
- Greyhound US
  
  35h 20m
  
  0
  
  9:25 PM
  
  Santa Ana, CA
  Bus Stop
  
  10:20 PM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $5
  
  A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/19/2026 9:25:00 PM to Union Station, Los Angeles (USA) arriving at 10/19/2026 10:20:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 55m
- FlixBus
  
  25h 10m
  
  0
  
  7:35 AM
  
  Los Angeles
  North Hollywood
  
  8:45 AM
  
  Portland, OR
  Greyhound Bus Station
  
  0
  
  Economy
  
  $95
  
  A Bus from FlixBus goes from North Hollywood, Los Angeles (USA) at 10/20/2026 7:35:00 AM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/21/2026 8:45:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 25h 10m
Travel time is 10h 15m longer, but you will save $26

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 5m	7:40 AM	Santa Ana, CA	Bus Stop	8:45 AM	Portland, OR	Union Bus Station		Economy	$133	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/21/2026 7:40:00 AM to Union Bus Station, Portland, OR (USA) arriving at 10/22/2026 8:45:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 25h 5m
	Greyhound US	28h 5m	9:25 PM	Santa Ana, CA	Bus Stop	1:30 AM	Portland, OR	Union Bus Station		Economy	$176	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/21/2026 9:25:00 PM to Union Bus Station, Portland, OR (USA) arriving at 10/23/2026 1:30:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 28h 5m

Did you know that if you travel from Santa Ana, CA to Portland, OR via Los Angeles, you can save more than $35? You can find the corresponding connections below.
- Greyhound US
  
  37h 15m
  
  0
  
  7:30 PM
  
  Santa Ana, CA
  Bus Stop
  
  9:15 PM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $6
  
  A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/21/2026 7:30:00 PM to Union Station, Los Angeles (USA) arriving at 10/21/2026 9:15:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 45m
- FlixBus
  
  25h 10m
  
  0
  
  7:35 AM
  
  Los Angeles
  North Hollywood
  
  8:45 AM
  
  Portland, OR
  Greyhound Bus Station
  
  0
  
  Economy
  
  $92
  
  A Bus from FlixBus goes from North Hollywood, Los Angeles (USA) at 10/22/2026 7:35:00 AM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/23/2026 8:45:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 25h 10m
Travel time is 12h 10m longer, but you will save $35

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	25h 5m	7:40 AM	Santa Ana, CA	Bus Stop	8:45 AM	Portland, OR	Union Bus Station		Economy	$150	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/22/2026 7:40:00 AM to Union Bus Station, Portland, OR (USA) arriving at 10/23/2026 8:45:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 25h 5m
	Greyhound US	28h 5m	9:25 PM	Santa Ana, CA	Bus Stop	1:30 AM	Portland, OR	Union Bus Station		Economy	$171	A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/22/2026 9:25:00 PM to Union Bus Station, Portland, OR (USA) arriving at 10/24/2026 1:30:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 28h 5m

Did you know that if you travel from Santa Ana, CA to Portland, OR via Los Angeles, you can save more than $52? You can find the corresponding connections below.
- Greyhound US
  
  37h 15m
  
  0
  
  7:30 PM
  
  Santa Ana, CA
  Bus Stop
  
  9:15 PM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $6
  
  A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 10/21/2026 7:30:00 PM to Union Station, Los Angeles (USA) arriving at 10/21/2026 9:15:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 45m
- FlixBus
  
  25h 10m
  
  0
  
  7:35 AM
  
  Los Angeles
  North Hollywood
  
  8:45 AM
  
  Portland, OR
  Greyhound Bus Station
  
  0
  
  Economy
  
  $92
  
  A Bus from FlixBus goes from North Hollywood, Los Angeles (USA) at 10/22/2026 7:35:00 AM to Greyhound Bus Station, Portland, OR (USA) arriving at 10/23/2026 8:45:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 25h 10m
Travel time is 12h 10m longer, but you will save $52

Best Price Offer: The price for the cheapest bus from Santa Ana, CA to Portland, OR is $115 on 11/5/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Santa Ana, CA and Portland, OR

See here how frequent the connections between Santa Ana, CA and Portland, OR are, during different times and days of the week.

Sunday is the busiest day, with more than 2 daily buses from Santa Ana, CA to Portland, OR. Sunday has instead the fewest connections, with only 2 daily coaches between Santa Ana, CA and Portland, OR.

The busiest time of the day is the Morning, with 6 buses from Santa Ana, CA to Portland, OR, while Morning sees the fewest connections between Santa Ana, CA and Portland, OR, with 6 offers.

Facts about the bus from Santa Ana, CA to Portland, OR

Compare all providers like Greyhound US that travel 2 times every day by bus from Santa Ana, CA to Portland, OR in one click! Book your bus ticket from Santa Ana, CA to Portland, OR starting from $115!

Cheapest Bus	$115
Fastest Bus	25h 5m
Earliest Bus	7:40 AM
Latest Bus	9:25 PM
Daily Bus Routes	2 Ø
Distance	852.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Santa Ana, CA to Portland, OR

Every day, 2 buses from 1 bus companies leave Santa Ana, CA for Portland, OR: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/16/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/11

Monday 10/12

Tuesday 10/13

Wednesday 10/14

Thursday 10/15

Friday 10/16

$168

Saturday 10/17

$144

Sunday 10/18

$150

Monday 10/19

$126

Tuesday 10/20

Wednesday 10/21

$133

Thursday 10/22

$150

Friday 10/23

$149

Saturday 10/24

$146

Sunday 10/25

$150

Monday 10/26

$138

Tuesday 10/27

$144

Wednesday 10/28

$143

Thursday 10/29

$125

Friday 10/30

$135

Saturday 10/31

$122

Sunday 11/01

Monday 11/02

$134

Tuesday 11/03

$130

Wednesday 11/04

$122

Thursday 11/05

$115

Friday 11/06

$128

Saturday 11/07

The cheapest time to travel from Santa Ana, CA to Portland, OR

See here on which day and which time of the day you can find the cheapest bus ticket from Santa Ana, CA to Portland, OR, for the next 30 days.

With a price starting from $113, Saturday is the cheapest day for a bus from Santa Ana, CA to Portland, OR. Sunday instead is the most expensive day with prices starting from $133.

Morning is the cheapest day time for bus tickets from Santa Ana, CA to Portland, OR, with $126. Evening is the most expensive time of the day with prices starting from $134.

How to save money travelling from Santa Ana, CA to Portland, OR

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santa Ana, CA to Portland, OR in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Ana, CA to Portland, OR, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Ana, CA to Portland, OR are also emptier.

All bus stations and stops in Santa Ana, CA and Portland, OR

In the map below, you can see where to find all bus stations in Santa Ana, CA and Portland, OR.

Bus Stop

1000 E Santa Ana Blvd 105

Train Station

W 1st St 101-155

Union Bus Station

NW 6th Ave 800

NW Station Way

NW Station Way 1090

Greyhound Bus Station

NW Station Way 1090

Portland Bolt Lloyd Center

NE 13th Ave 1060

SE 102nd & Washington Bus Stop

Service and Comfort on the bus from Santa Ana, CA to Portland, OR

Want to know which seat classes are available on the buses from Santa Ana, CA to Portland, OR? Or which bus companies serve the route Santa Ana, CA to Portland, OR? Below you will find answers to your questions.

FAQs about the Santa Ana, CA to Portland, OR bus

How much does a Santa Ana, CA Portland, OR bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $115 and takes 25h 5m to reach Portland, OR. Compare offers to save money!

How much could I save by comparing buses from Santa Ana, CA to Portland, OR?

This route is offered by 1 companies with a range of ticket prices between $115 and $189. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Portland, OR.

On average, how many connections are available from Santa Ana, CA to Portland, OR each day?

Every day, the Santa Ana, CA to Portland, OR bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santa Ana, CA to Portland, OR take?

The fastest bus from Santa Ana, CA to Portland, OR is offered by Greyhound US and takes 25h 5m. Bus tickets for this connection cost $168. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santa Ana, CA to Portland, OR?

The earliest bus arriving in Portland, OR from Santa Ana, CA starts at 7:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santa Ana, CA to Portland, OR?

The latest bus trip departing from Santa Ana, CA for Portland, OR starts at 9:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santa Ana, CA Portland, OR route?

When traveling by bus from Santa Ana, CA to Portland, OR, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santa Ana, CA and Portland, OR?

You can check all the direct connections between Santa Ana, CA and Portland, OR by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Santa Ana, CA to Portland, OR bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santa Ana, CA Portland, OR bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Ana, CA Portland, OR bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Ana, CA to Portland, OR on your planned travel date.

How does CheckMyBus find the best bus deals from Santa Ana, CA to Portland, OR?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Santa Ana, CA and Portland, OR. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santa Ana, CA to Portland, OR?

Prices and availability for 2 trips between Santa Ana, CA and Portland, OR change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santa Ana, CA to Portland, OR

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santa Ana, CA and to Portland, OR

Here’s an overview of the most popular bus routes to Santa Ana, CA and to Portland, OR. Simply click on the connection of your choice, and you will find all the details about your bus route!