Bus from Santiago del Estero to Buenos Aires from $40

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Compare all timetables for the bus from Santiago del Estero to Buenos Aires

Here is a selection of the cheapest bus trips from the schedule from Santiago del Estero to Buenos Aires from various bus operators like Balut, Flecha Bus or 20 de Junio for the next days.

today
$44
tomorrow
$51
Tuesday
$44
Wednesday
$44
Thursday
$44
Friday
$46
Saturday
$40

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
20 de Junio 16h 40m 3:21 PM Santiago del Estero Central Bus Station 8:01 AM Buenos Aires Retiro Bus Station  Premium Economy $44
Crucero del Sur 15h 10m 10:20 PM Santiago del Estero Central Bus Station 1:30 PM Buenos Aires Retiro Bus Station  Premium Economy $52
Balut 15h 0m 1:40 AM Santiago del Estero Central Bus Station 4:40 PM Buenos Aires Retiro Bus Station  Premium Economy $59
Transporte La Union 18h 0m 12:30 PM Santiago del Estero Central Bus Station 6:30 AM Buenos Aires Retiro Bus Station  Premium Economy $59
La Veloz del Norte 15h 0m 12:10 AM Santiago del Estero Central Bus Station 3:10 PM Buenos Aires Retiro Bus Station  Premium Economy $60

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
20 de Junio 16h 40m 1:20 AM Santiago del Estero Central Bus Station 6:00 PM Buenos Aires Retiro Bus Station  Premium Economy $51
Balut 15h 0m 1:40 AM Santiago del Estero Central Bus Station 4:40 PM Buenos Aires Retiro Bus Station  Premium Economy $59
Transporte La Union 18h 0m 12:30 PM Santiago del Estero Central Bus Station 6:30 AM Buenos Aires Retiro Bus Station  Premium Economy $59
La Veloz del Norte 15h 0m 12:10 AM Santiago del Estero Central Bus Station 3:10 PM Buenos Aires Retiro Bus Station  Premium Economy $60
Flecha Bus 15h 50m 5:50 PM Santiago del Estero Central Bus Station 9:40 AM Buenos Aires Retiro Bus Station  Premium Economy $60
  • Did you know that if you travel from Santiago del Estero to Buenos Aires via Rosario, SF, you can save more than $11? You can find the corresponding connections below.
    • Central de Pasajes
      16h 40m
      0
      1:20 AM
      Santiago del Estero
      Central Bus Station
      1:25 PM
      Rosario, SF
      Bus Station
      0
      Central de Pasajes
      Premium Economy
      $25
      • Waiting Time 0h 5m
    • Plataforma 10
      4h 30m
      0
      1:30 PM
      Rosario, SF
      Bus Station
      6:00 PM
      Buenos Aires
      Retiro Bus Station
      0
      Plataforma 10
      Premium Economy
      $15
    Travel time is 1h 40m longer, but you will save $11

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
20 de Junio 16h 40m 1:20 AM Santiago del Estero Central Bus Station 6:00 PM Buenos Aires Retiro Bus Station  Premium Economy $44
Crucero del Sur 15h 15m 10:15 PM Santiago del Estero Central Bus Station 1:30 PM Buenos Aires Retiro Bus Station  Premium Economy $52
Flecha Bus 15h 0m 12:40 AM Santiago del Estero Central Bus Station 3:40 PM Buenos Aires Retiro Bus Station  Premium Economy $57
Balut 15h 0m 1:40 AM Santiago del Estero Central Bus Station 4:40 PM Buenos Aires Retiro Bus Station  Premium Economy $59
La Unión 18h 0m 12:30 PM Santiago del Estero Central Bus Station 6:30 AM Buenos Aires Retiro Bus Station  Premium Economy $59
  • Did you know that if you travel from Santiago del Estero to Buenos Aires via Rosario, SF, you can save more than $4? You can find the corresponding connections below.
    • Central de Pasajes
      16h 40m
      0
      1:20 AM
      Santiago del Estero
      Central Bus Station
      1:25 PM
      Rosario, SF
      Bus Station
      0
      Central de Pasajes
      Premium Economy
      $25
      • Waiting Time 0h 5m
    • Plataforma 10
      4h 30m
      0
      1:30 PM
      Rosario, SF
      Bus Station
      6:00 PM
      Buenos Aires
      Retiro Bus Station
      0
      Plataforma 10
      Premium Economy
      $15
    Travel time is 1h 40m longer, but you will save $4

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
20 de Junio 16h 40m 1:20 AM Santiago del Estero Central Bus Station 6:00 PM Buenos Aires Retiro Bus Station  Premium Economy $44
Flecha Bus 15h 0m 12:40 AM Santiago del Estero Central Bus Station 3:40 PM Buenos Aires Retiro Bus Station  Premium Economy $57
Balut 15h 0m 1:40 AM Santiago del Estero Central Bus Station 4:40 PM Buenos Aires Retiro Bus Station  Premium Economy $59
Transporte La Union 18h 0m 12:30 PM Santiago del Estero Central Bus Station 6:30 AM Buenos Aires Retiro Bus Station  Premium Economy $59
La Veloz del Norte 15h 0m 12:10 AM Santiago del Estero Central Bus Station 3:10 PM Buenos Aires Retiro Bus Station  Premium Economy $60
  • Did you know that if you travel from Santiago del Estero to Buenos Aires via Rosario, SF, you can save more than $4? You can find the corresponding connections below.
    • Central de Pasajes
      16h 40m
      0
      1:20 AM
      Santiago del Estero
      Central Bus Station
      1:25 PM
      Rosario, SF
      Bus Station
      0
      Central de Pasajes
      Premium Economy
      $25
      • Waiting Time 0h 5m
    • Plataforma 10
      4h 30m
      0
      1:30 PM
      Rosario, SF
      Bus Station
      6:00 PM
      Buenos Aires
      Retiro Bus Station
      0
      Plataforma 10
      Premium Economy
      $15
    Travel time is 1h 40m longer, but you will save $4

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
20 de Junio 16h 40m 1:20 AM Santiago del Estero Central Bus Station 6:00 PM Buenos Aires Retiro Bus Station  Premium Economy $44
Crucero del Sur 15h 10m 10:20 PM Santiago del Estero Central Bus Station 1:30 PM Buenos Aires Retiro Bus Station  Premium Economy $52
Flecha Bus 15h 0m 12:40 AM Santiago del Estero Central Bus Station 3:40 PM Buenos Aires Retiro Bus Station  Premium Economy $57
Balut 15h 0m 1:40 AM Santiago del Estero Central Bus Station 4:40 PM Buenos Aires Retiro Bus Station  Premium Economy $59
La Unión 18h 0m 12:30 PM Santiago del Estero Central Bus Station 6:30 AM Buenos Aires Retiro Bus Station  Premium Economy $59
  • Did you know that if you travel from Santiago del Estero to Buenos Aires via Rosario, SF, you can save more than $4? You can find the corresponding connections below.
    • Central de Pasajes
      16h 40m
      0
      1:20 AM
      Santiago del Estero
      Central Bus Station
      1:25 PM
      Rosario, SF
      Bus Station
      0
      Central de Pasajes
      Premium Economy
      $25
      • Waiting Time 0h 5m
    • Plataforma 10
      4h 30m
      0
      1:30 PM
      Rosario, SF
      Bus Station
      6:00 PM
      Buenos Aires
      Retiro Bus Station
      0
      Plataforma 10
      Premium Economy
      $15
    Travel time is 1h 40m longer, but you will save $4

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
20 de Junio 16h 40m 1:20 AM Santiago del Estero Bus Stop 6:00 PM Buenos Aires Retiro Bus Station  Premium Economy $46
Crucero del Sur 15h 10m 10:20 PM Santiago del Estero Central Bus Station 1:30 PM Buenos Aires Retiro Bus Station  Premium Economy $52
Balut 15h 0m 1:40 AM Santiago del Estero Central Bus Station 4:40 PM Buenos Aires Retiro Bus Station  Premium Economy $59
La Unión 18h 0m 12:30 PM Santiago del Estero Central Bus Station 6:30 AM Buenos Aires Retiro Bus Station  Premium Economy $59
La Veloz del Norte 15h 0m 12:10 AM Santiago del Estero Central Bus Station 3:10 PM Buenos Aires Retiro Bus Station  Premium Economy $60
  • Did you know that if you travel from Santiago del Estero to Buenos Aires via Rosario, SF, you can save more than $6? You can find the corresponding connections below.
    • Central de Pasajes
      16h 40m
      0
      1:20 AM
      Santiago del Estero
      Central Bus Station
      1:25 PM
      Rosario, SF
      Bus Station
      0
      Central de Pasajes
      Premium Economy
      $25
      • Waiting Time 0h 5m
    • Plataforma 10
      4h 30m
      0
      1:30 PM
      Rosario, SF
      Bus Station
      6:00 PM
      Buenos Aires
      Retiro Bus Station
      0
      Plataforma 10
      Premium Economy
      $15
    Travel time is 1h 40m longer, but you will save $6

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
20 de Junio 16h 40m 1:20 AM Santiago del Estero Central Bus Station 6:00 PM Buenos Aires Retiro Bus Station  Premium Economy $40
Crucero del Sur 15h 10m 10:20 PM Santiago del Estero Central Bus Station 1:30 PM Buenos Aires Retiro Bus Station  Premium Economy $52
Flecha Bus 15h 0m 12:40 AM Santiago del Estero Central Bus Station 3:40 PM Buenos Aires Retiro Bus Station  Premium Economy $57
Balut 15h 0m 1:40 AM Santiago del Estero Central Bus Station 4:40 PM Buenos Aires Retiro Bus Station  Premium Economy $59
La Unión 18h 0m 12:30 PM Santiago del Estero Central Bus Station 6:30 AM Buenos Aires Retiro Bus Station  Premium Economy $59

Best Price Offer: The price for the cheapest bus from Santiago del Estero to Buenos Aires is $40 on 2/14/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Santiago del Estero and Buenos Aires

See here how frequent the connections between Santiago del Estero and Buenos Aires are, during different times and days of the week.
Tuesday is the busiest day, with more than 118 daily buses from Santiago del Estero to Buenos Aires. Monday has instead the fewest connections, with only 60 daily coaches between Santiago del Estero and Buenos Aires.
The busiest time of the day is the Night, with 340 buses from Santiago del Estero to Buenos Aires, while Evening sees the fewest connections between Santiago del Estero and Buenos Aires, with 120 offers.

Facts about the bus from Santiago del Estero to Buenos Aires

Compare all providers like Balut, Flecha Bus and 20 de Junio that travel 91 times every day by bus from Santiago del Estero to Buenos Aires in one click! Book your bus ticket from Santiago del Estero to Buenos Aires starting from $40!

Cheapest Bus $40
Fastest Bus 12h 20m
Earliest Bus 12:10 AM
Latest Bus 10:40 PM
Daily Bus Routes 91 Ø
Distance 586.1 miles
Bus Companies Balut, Flecha Bus, 20 de Junio, Vosa, Rutatlántica, La Veloz del Norte, Almirante Brown, Transporte La Union, Crucero del Sur, Vía Tac and 1 more.

Cheapest bus connections from Santiago del Estero to Buenos Aires

Every day, 91 buses from 11 bus companies leave Santiago del Estero for Buenos Aires: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/08/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/08
$59
Monday 02/09
$51
Tuesday 02/10
$74
Wednesday 02/11
$59
Thursday 02/12
$51
Friday 02/13
$59
Saturday 02/14
$52
Sunday 02/15
$60
Monday 02/16
$51
Tuesday 02/17
$52
Wednesday 02/18
$44
Thursday 02/19
$44
Friday 02/20
$44
Saturday 02/21
$44
Sunday 02/22
$44
Monday 02/23
$52
Tuesday 02/24
$44
Wednesday 02/25
$44
Thursday 02/26
$44
Friday 02/27
$44
Saturday 02/28
$44
Sunday 03/01
$44
Monday 03/02
$44
Tuesday 03/03
$44
Wednesday 03/04
$44
Thursday 03/05
$44
Friday 03/06
$44
Saturday 03/07

The cheapest time to travel from Santiago del Estero to Buenos Aires

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago del Estero to Buenos Aires, for the next 30 days.
With a price starting from $40, Saturday is the cheapest day for a bus from Santiago del Estero to Buenos Aires. Monday instead is the most expensive day with prices starting from $44.
Afternoon is the cheapest day time for bus tickets from Santiago del Estero to Buenos Aires, with $40. Evening is the most expensive time of the day with prices starting from $52.

How to save money travelling from Santiago del Estero to Buenos Aires

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago del Estero to Buenos Aires in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago del Estero to Buenos Aires, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago del Estero to Buenos Aires are also emptier.

Beloved bus companies from Santiago del Estero to Buenos Aires

These are the most booked bus companies between Santiago del Estero to Buenos Aires from our users.

Flecha Bus from Santiago del Estero to Buenos Aires

Flecha Bus

Here you will find the key facts about the Flecha Bus bus route Santiago del Estero to Buenos Aires:

Cheapest Price $57
Fastest Bus 13h 40m
Earliest Bus 12:20 AM
Last Bus 9:45 PM
Daily Connections 16 Ø
Found on 2/7/2026

Crucero del Sur from Santiago del Estero to Buenos Aires

Crucero del Sur

Here you will find the key facts about the Crucero del Sur bus route Santiago del Estero to Buenos Aires:

Cheapest Price $52
Fastest Bus 15h 10m
Earliest Bus 10:20 PM
Last Bus 10:20 PM
Daily Connections 2 Ø
Found on 2/7/2026

Latest reviews for bus companies on the route Santiago del Estero - Buenos Aires

Vía Bariloche
Nicole, 10/14/2025
Impuntuales totalmente siempre! Porque no es la primera vez y lo comentamos entre varios pasajeros. Teníamos que llegar 8.20 am a retiro, son las 10.30 am seguimos por liniers, cuando primero tenía qu ... Impuntuales totalmente siempre! Porque no es la primera vez y lo comentamos entre varios pasajeros. Teníamos que llegar 8.20 am a retiro, son las 10.30 am seguimos por liniers, cuando primero tenía que pasar por retiro según el recorrido online. Por ende van más de dos horas de demora en la hora de llegada. Tenemos turnos medicos y juegan con la salud y tiempo de la gente. Sumamente impuntuales llegó tarde a buscarnos llega tarde a dejarnos

All bus stations and stops in Santiago del Estero and Buenos Aires

In the map below, you can see where to find all bus stations in Santiago del Estero and Buenos Aires.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago del Estero to Buenos Aires? Compare all modes of transports from Santiago del Estero to Buenos Aires.

Service and Comfort on the bus from Santiago del Estero to Buenos Aires

Want to know which seat classes are available on the buses from Santiago del Estero to Buenos Aires? Or which bus companies serve the route Santiago del Estero to Buenos Aires? Below you will find answers to your questions.

FAQs about the Santiago del Estero to Buenos Aires bus

How much does a Santiago del Estero Buenos Aires bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $40 and takes 16h 40m to reach Buenos Aires. Compare offers to save money!

How much could I save by comparing buses from Santiago del Estero to Buenos Aires?

This route is offered by 11 companies with a range of ticket prices between $40 and $103. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Buenos Aires.

On average, how many connections are available from Santiago del Estero to Buenos Aires each day?

Every day, the Santiago del Estero to Buenos Aires bus route is served by approximately 91 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago del Estero to Buenos Aires take?

The fastest bus from Santiago del Estero to Buenos Aires is offered by Vosa and takes 12h 20m. Bus tickets for this connection cost $80. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago del Estero to Buenos Aires?

The earliest bus arriving in Buenos Aires from Santiago del Estero starts at 12:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago del Estero to Buenos Aires?

The latest bus trip departing from Santiago del Estero for Buenos Aires starts at 10:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago del Estero Buenos Aires route?

When traveling by bus from Santiago del Estero to Buenos Aires, passengers can travel with Balut, Flecha Bus and 20 de Junio. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago del Estero and Buenos Aires?

You can check all the direct connections between Santiago del Estero and Buenos Aires by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Balut, Flecha Bus and 20 de Junio.

What can I take with me on the Santiago del Estero to Buenos Aires bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago del Estero Buenos Aires bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago del Estero Buenos Aires bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago del Estero to Buenos Aires on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago del Estero to Buenos Aires?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 91 daily trips between Santiago del Estero and Buenos Aires. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago del Estero to Buenos Aires?

Prices and availability for 91 trips between Santiago del Estero and Buenos Aires change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago del Estero to Buenos Aires

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Santiago del Estero and to Buenos Aires

Here’s an overview of the most popular bus routes to Santiago del Estero and to Buenos Aires. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Río Gallegos to Santiago del Estero Bus Río Gallegos to Santiago del Estero
From San Miguel de Tucumán to Santiago del Estero bus From San Miguel de Tucumán to Santiago del Estero bus
Córdoba, CD to Santiago del Estero bus Córdoba, CD to Santiago del Estero bus
Bus Mendoza - Santiago del Estero Bus Mendoza - Santiago del Estero
Bus from San Juan Bautista to Buenos Aires Bus from San Juan Bautista to Buenos Aires
Bus from Tartagal to Buenos Aires Bus from Tartagal to Buenos Aires
Bus Itá - Buenos Aires Bus Itá - Buenos Aires
Buses to Buenos Aires from Azul Buses to Buenos Aires from Azul
Popular Airport Shuttles to Santiago del Estero and to Buenos Aires
CheckMyBus › Buses in Argentina › Bus to Santiago del Estero › Bus to Buenos Aires

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