Bus Santiago Tuxtla to Mexico City: Compare prices and save money

Compare all timetables for the bus from Santiago Tuxtla to Mexico City

Here is a selection of the cheapest bus trips from the schedule from Santiago Tuxtla to Mexico City from various bus operators like ADO for the next days.

today

$70

tomorrow

Thursday

Friday

$70

Saturday

Sunday

Monday

$70

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	8h 55m	9:20 PM	Santiago Tuxtla	Central Bus Station	6:15 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/24/2026 9:20:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/25/2026 6:15:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 8h 55m
ADO	8h 55m	10:00 PM	Santiago Tuxtla	Central Bus Station	6:55 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/24/2026 10:00:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/25/2026 6:55:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 8h 55m
ADO	9h 15m	10:15 PM	Santiago Tuxtla	Central Bus Station	7:30 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/24/2026 10:15:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/25/2026 7:30:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 15m
ADO	10h 0m	10:15 PM	Santiago Tuxtla	Central Bus Station	8:15 AM	Mexico City	Norte Bus Station	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/24/2026 10:15:00 PM to Norte Bus Station, Mexico City (Mexico) arriving at 3/25/2026 8:15:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 10h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	8h 55m	9:15 PM	Santiago Tuxtla	Central Bus Station	6:10 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/27/2026 9:15:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/28/2026 6:10:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 8h 55m
ADO	8h 55m	10:00 PM	Santiago Tuxtla	Central Bus Station	6:55 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/27/2026 10:00:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/28/2026 6:55:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 8h 55m
ADO	9h 15m	10:15 PM	Santiago Tuxtla	Central Bus Station	7:30 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/27/2026 10:15:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/28/2026 7:30:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 15m
ADO	10h 0m	10:15 PM	Santiago Tuxtla	Central Bus Station	8:15 AM	Mexico City	Norte Bus Station	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/27/2026 10:15:00 PM to Norte Bus Station, Mexico City (Mexico) arriving at 3/28/2026 8:15:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 10h 0m

Did you know that if you travel from Santiago Tuxtla to Mexico City via Puebla City, PL, you can save more than $9? You can find the corresponding connections below.
- ADO
  
  11h 5m
  
  0
  
  10:00 PM
  
  Santiago Tuxtla
  Central Bus Station
  
  4:45 AM
  
  Puebla City, PL
  Central Bus Station (CAPU)
  
  0
  
  Economy
  
  $57
  
  A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/27/2026 10:00:00 PM to Central Bus Station (CAPU), Puebla City, PL (Mexico) arriving at 3/28/2026 4:45:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 6h 45m
- Flix Mexico
  
  3h 35m
  
  0
  
  5:30 AM
  
  Puebla City, PL
  Central Bus Station (CAPU)
  
  9:05 AM
  
  Mexico City
  Fórum Buenavista
  
  0
  
  Economy
  
  $4
  
  A Bus from Flix Mexico goes from Central Bus Station (CAPU), Puebla City, PL (Mexico) at 3/28/2026 5:30:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 3/28/2026 9:05:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 3h 35m
Travel time is 2h 10m longer, but you will save $9

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	9h 5m	9:15 PM	Santiago Tuxtla	Central Bus Station	6:20 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/30/2026 9:15:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/31/2026 6:20:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 5m
ADO	9h 5m	10:00 PM	Santiago Tuxtla	Central Bus Station	7:05 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/30/2026 10:00:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/31/2026 7:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 5m
ADO	9h 15m	10:20 PM	Santiago Tuxtla	Central Bus Station	7:35 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/30/2026 10:20:00 PM to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 3/31/2026 7:35:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 15m
ADO	10h 0m	10:20 PM	Santiago Tuxtla	Central Bus Station	8:20 AM	Mexico City	Norte Bus Station	Economy	$70	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/30/2026 10:20:00 PM to Norte Bus Station, Mexico City (Mexico) arriving at 3/31/2026 8:20:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 10h 0m

Did you know that if you travel from Santiago Tuxtla to Mexico City via Veracruz, you can save more than $19? You can find the corresponding connections below.
- ADO
  
  12h 20m
  
  0
  
  2:10 PM
  
  Santiago Tuxtla
  Central Bus Station
  
  5:05 PM
  
  Veracruz
  Central bus station
  
  0
  
  Economy
  
  $19
  
  A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 3/30/2026 2:10:00 PM to Central bus station, Veracruz (Mexico) arriving at 3/30/2026 5:05:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 2h 55m
- Conexión
  
  6h 30m
  
  0
  
  8:00 PM
  
  Veracruz
  Bus Stop
  
  2:30 AM
  
  Mexico City
  Norte Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from Conexión goes from Bus Stop, Veracruz (Mexico) at 3/30/2026 8:00:00 PM to Norte Bus Station, Mexico City (Mexico) arriving at 3/31/2026 2:30:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 30m
Travel time is 3h 15m longer, but you will save $19

Best Price Offer: The price for the cheapest bus from Santiago Tuxtla to Mexico City is $70 on 3/24/2026. Flexible travelers save on ticket prices.

Facts about the bus from Santiago Tuxtla to Mexico City

Compare all providers like ADO that travel 6 times every day by bus from Santiago Tuxtla to Mexico City in one click! Book your bus ticket from Santiago Tuxtla to Mexico City starting from $70!

Cheapest Bus	$70
Fastest Bus	8h 55m
Earliest Bus	9:20 PM
Latest Bus	10:20 PM
Daily Bus Routes	6 Ø
Distance	259.2 miles
Bus Companies	ADO

Cheapest bus connections from Santiago Tuxtla to Mexico City

Every day, 6 buses from 1 bus companies leave Santiago Tuxtla for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

Monday 03/23

Tuesday 03/24

$70

Wednesday 03/25

Thursday 03/26

Friday 03/27

$70

Saturday 03/28

Sunday 03/29

Monday 03/30

$70

Tuesday 03/31

$74

Wednesday 04/01

Thursday 04/02

Friday 04/03

Saturday 04/04

$73

Sunday 04/05

Monday 04/06

$72

Tuesday 04/07

Wednesday 04/08

Thursday 04/09

$70

Friday 04/10

Saturday 04/11

Sunday 04/12

$70

Monday 04/13

$72

Tuesday 04/14

Wednesday 04/15

$72

Thursday 04/16

$70

Friday 04/17

$73

Saturday 04/18

How to save money travelling from Santiago Tuxtla to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago Tuxtla to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago Tuxtla to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago Tuxtla to Mexico City are also emptier.

All bus stations and stops in Santiago Tuxtla and Mexico City

In the map below, you can see where to find all bus stations in Santiago Tuxtla and Mexico City.

Central Bus Station

Morelos 190

Norte Bus Station

Eje Central Lázaro Cárdenas

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Terminal del Sur

Av. Taxqueña 1320

Observatorio Central Bus Station

Av Río de Tacubaya 122 232

Eje Central Bus Stop

Avenida Lázaro Cárdenas & Calle Poniente 112 Avenida Lázaro Cárdenas & Calle Poniente 112

Service and Comfort on the bus from Santiago Tuxtla to Mexico City

Want to know which seat classes are available on the buses from Santiago Tuxtla to Mexico City? Or which bus companies serve the route Santiago Tuxtla to Mexico City? Below you will find answers to your questions.

FAQs about the Santiago Tuxtla to Mexico City bus

How much does a Santiago Tuxtla Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $70 and takes 8h 55m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from Santiago Tuxtla to Mexico City?

This route is offered by 1 companies with a range of ticket prices between $70 and $73. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from Santiago Tuxtla to Mexico City each day?

Every day, the Santiago Tuxtla to Mexico City bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago Tuxtla to Mexico City take?

The fastest bus from Santiago Tuxtla to Mexico City is offered by ADO and takes 8h 55m. Bus tickets for this connection cost $70. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago Tuxtla to Mexico City?

The earliest bus arriving in Mexico City from Santiago Tuxtla starts at 9:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago Tuxtla to Mexico City?

The latest bus trip departing from Santiago Tuxtla for Mexico City starts at 10:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago Tuxtla Mexico City route?

When traveling by bus from Santiago Tuxtla to Mexico City, passengers can travel with ADO. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago Tuxtla and Mexico City?

You can check all the direct connections between Santiago Tuxtla and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ADO.

What can I take with me on the Santiago Tuxtla to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago Tuxtla Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago Tuxtla Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago Tuxtla to Mexico City on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago Tuxtla to Mexico City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Santiago Tuxtla and Mexico City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago Tuxtla to Mexico City?

Prices and availability for 6 trips between Santiago Tuxtla and Mexico City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago Tuxtla to Mexico City

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santiago Tuxtla and to Mexico City

Here’s an overview of the most popular bus routes to Santiago Tuxtla and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!