What is the best way to travel from Karlsruhe to Brussels?
Looking for a trip? Compare all the available Buses, Trains and Flights for the journey to Brussels from Karlsruhe. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Karlsruhe?
You can get to Brussels with just $28 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus7h 30m010:45 AMKarlsruheCentral Station6:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/14/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/14/2025 6:15:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 30m
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FlixBus7h 35m011:10 PMKarlsruheCentral Station6:45 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/14/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/15/2025 6:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 7h 35m
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FlixBus9h 40m06:50 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/14/2025 6:50:00 AM to North Station, Brussels (Belgium) arriving at 12/14/2025 4:30:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 9h 40m
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BlaBlaCar Bus7h 50m09:05 PMKarlsruheCentral Station4:55 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 12/14/2025 9:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/15/2025 4:55:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 7h 50m
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Lauda Europe24h 40m03:45 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:25 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lauda Europe goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/14/2025 3:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/15/2025 4:25:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 40m
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LC Perú8h 25m07:35 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:00 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from LC Perú goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/14/2025 7:35:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/14/2025 4:00:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 8h 25m
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Skyscanner20h 5m04:10 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport12:15 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/14/2025 4:10:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/15/2025 12:15:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 5m
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Skyscanner19h 55m012:40 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:35 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/14/2025 12:40:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/15/2025 8:35:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 19h 55m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Lauda Europe8h 45m07:40 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:25 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lauda Europe goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/15/2025 7:40:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/15/2025 4:25:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 8h 45m
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Skyscanner10h 35m011:15 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport9:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/15/2025 11:15:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/15/2025 9:50:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 10h 35m
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Skyscanner7h 20m06:00 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport1:20 PMBrussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/15/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/15/2025 1:20:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 7h 20m
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Skyscanner8h 30m06:00 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport2:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/15/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/15/2025 2:30:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 8h 30m
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Deutsche Bahn5h 36m06:41 PMKarlsruheCentral Station12:17 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Karlsruhe (Germany) at 12/15/2025 6:41:00 PM to Central Station, Brussels (Belgium) arriving at 12/16/2025 12:17:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 5h 36m
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Deutsche Bahn4h 53m02:41 PMKarlsruheCentral Station7:34 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Karlsruhe (Germany) at 12/15/2025 2:41:00 PM to Central Station, Brussels (Belgium) arriving at 12/15/2025 7:34:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 4h 53m
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Deutsche Bahn4h 53m04:41 PMKarlsruheCentral Station9:34 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Karlsruhe (Germany) at 12/15/2025 4:41:00 PM to Central Station, Brussels (Belgium) arriving at 12/15/2025 9:34:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 4h 53m
Cheapest Flights Monday
Cheapest Trains Monday
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FlixBus10h 50m03:50 AMKarlsruheCentral Station2:40 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/16/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/16/2025 2:40:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 10h 50m
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FlixBus10h 35m05:55 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/16/2025 5:55:00 AM to North Station, Brussels (Belgium) arriving at 12/16/2025 4:30:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 10h 35m
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FlixBus7h 30m010:45 AMKarlsruheCentral Station6:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/16/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/16/2025 6:15:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 7h 30m
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FlixBus7h 35m011:10 PMKarlsruheCentral Station6:45 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/16/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/17/2025 6:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 7h 35m
Cheapest Buses Tuesday
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FlixBus10h 50m03:50 AMKarlsruheCentral Station2:40 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/18/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/18/2025 2:40:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 50m
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FlixBus10h 15m06:15 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/18/2025 6:15:00 AM to North Station, Brussels (Belgium) arriving at 12/18/2025 4:30:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 15m
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FlixBus10h 20m08:25 AMKarlsruheCentral Station6:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/18/2025 8:25:00 AM to North Station, Brussels (Belgium) arriving at 12/18/2025 6:45:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 20m
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FlixBus10h 5m09:15 PMKarlsruheCentral Station7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/18/2025 9:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/19/2025 7:20:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 5m
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Ryanair25h 25m06:55 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/18/2025 6:55:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/19/2025 8:20:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 25m
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Lauda Europe8h 25m08:20 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:45 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lauda Europe goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/18/2025 8:20:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/18/2025 4:45:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 8h 25m
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Skyscanner10h 30m06:05 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:35 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/18/2025 6:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/18/2025 4:35:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 10h 30m
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Wizz Air16h 30m04:25 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:55 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/18/2025 4:25:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/19/2025 8:55:00 AM. 50 Economy ticket for $246 per person are available. Travel duration is 16h 30m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus10h 20m08:25 AMKarlsruheCentral Station6:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/19/2025 8:25:00 AM to North Station, Brussels (Belgium) arriving at 12/19/2025 6:45:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 10h 20m
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FlixBus10h 50m03:50 AMKarlsruheCentral Station2:40 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/19/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/19/2025 2:40:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 50m
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FlixBus10h 35m05:55 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/19/2025 5:55:00 AM to North Station, Brussels (Belgium) arriving at 12/19/2025 4:30:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 35m
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FlixBus10h 35m04:50 PMKarlsruheCentral Station3:25 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/19/2025 4:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/20/2025 3:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 10h 35m
Cheapest Buses Friday
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FlixBus7h 30m010:45 AMKarlsruheCentral Station6:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/20/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/20/2025 6:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 30m
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FlixBus7h 35m011:10 PMKarlsruheCentral Station6:45 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/20/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/21/2025 6:45:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 7h 35m
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FlixBus10h 5m09:15 PMKarlsruheCentral Station7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/20/2025 9:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/21/2025 7:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 10h 5m
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FlixBus9h 40m03:50 AMKarlsruheCentral Station1:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/20/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/20/2025 1:30:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 9h 40m
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Skyscanner13h 30m06:40 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/20/2025 6:40:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/20/2025 8:10:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 13h 30m
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Skyscanner9h 10m011:00 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/20/2025 11:00:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/20/2025 8:10:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 9h 10m
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Skyscanner25h 0m012:05 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport1:05 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/20/2025 12:05:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/21/2025 1:05:00 PM. 50 Economy ticket for $295 per person are available. Travel duration is 25h 0m
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Ryanair28h 5m04:35 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:40 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/20/2025 4:35:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/21/2025 8:40:00 PM. 50 Economy ticket for $333 per person are available. Travel duration is 28h 5m
Cheapest Buses Saturday
Cheapest Flights Saturday
What are the fastest trips from Karlsruhe to Brussels?
You can get to Brussels from Karlsruhe in just 4h 53m with a Train from Deutsche Bahn. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus7h 30m010:45 AMKarlsruheCentral Station6:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/14/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/14/2025 6:15:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 30m
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FlixBus7h 35m011:10 PMKarlsruheCentral Station6:45 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/14/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/15/2025 6:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 7h 35m
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BlaBlaCar Bus7h 50m09:05 PMKarlsruheCentral Station4:55 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 12/14/2025 9:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/15/2025 4:55:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 7h 50m
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FlixBus9h 40m06:50 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/14/2025 6:50:00 AM to North Station, Brussels (Belgium) arriving at 12/14/2025 4:30:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 9h 40m
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LC Perú8h 25m07:35 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:00 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from LC Perú goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/14/2025 7:35:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/14/2025 4:00:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 8h 25m
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Ryanair10h 40m011:40 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/14/2025 11:40:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/14/2025 10:20:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 10h 40m
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Skyscanner15h 30m06:20 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport9:50 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/14/2025 6:20:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/14/2025 9:50:00 PM. 50 Economy ticket for $350 per person are available. Travel duration is 15h 30m
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Skyscanner19h 55m012:40 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:35 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/14/2025 12:40:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/15/2025 8:35:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 19h 55m
Fastest Buses Sunday
Fastest Flights Sunday
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Deutsche Bahn4h 53m02:41 PMKarlsruheCentral Station7:34 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Karlsruhe (Germany) at 12/15/2025 2:41:00 PM to Central Station, Brussels (Belgium) arriving at 12/15/2025 7:34:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 4h 53m
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Deutsche Bahn4h 53m04:41 PMKarlsruheCentral Station9:34 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Karlsruhe (Germany) at 12/15/2025 4:41:00 PM to Central Station, Brussels (Belgium) arriving at 12/15/2025 9:34:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 4h 53m
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Deutsche Bahn5h 36m06:41 PMKarlsruheCentral Station12:17 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Karlsruhe (Germany) at 12/15/2025 6:41:00 PM to Central Station, Brussels (Belgium) arriving at 12/16/2025 12:17:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 5h 36m
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Skyscanner7h 20m06:00 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport1:20 PMBrussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/15/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/15/2025 1:20:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 7h 20m
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Skyscanner7h 25m06:20 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport1:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/15/2025 6:20:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/15/2025 1:45:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 7h 25m
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Skyscanner8h 30m06:00 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport2:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/15/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/15/2025 2:30:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 8h 30m
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Lauda Europe8h 45m07:40 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:25 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lauda Europe goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/15/2025 7:40:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/15/2025 4:25:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 8h 45m
Fastest Trains Monday
Fastest Flights Monday
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FlixBus7h 30m010:45 AMKarlsruheCentral Station6:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/16/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/16/2025 6:15:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 7h 30m
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FlixBus7h 35m011:10 PMKarlsruheCentral Station6:45 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/16/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/17/2025 6:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 7h 35m
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FlixBus10h 35m05:55 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/16/2025 5:55:00 AM to North Station, Brussels (Belgium) arriving at 12/16/2025 4:30:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 10h 35m
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FlixBus10h 45m04:50 PMKarlsruheCentral Station3:35 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/16/2025 4:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/17/2025 3:35:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 10h 45m
Fastest Buses Tuesday
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FlixBus7h 35m011:10 PMKarlsruheCentral Station6:45 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/18/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/19/2025 6:45:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 35m
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FlixBus10h 5m09:15 PMKarlsruheCentral Station7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/18/2025 9:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/19/2025 7:20:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 5m
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FlixBus10h 15m06:15 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/18/2025 6:15:00 AM to North Station, Brussels (Belgium) arriving at 12/18/2025 4:30:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 15m
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FlixBus10h 20m08:25 AMKarlsruheCentral Station6:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/18/2025 8:25:00 AM to North Station, Brussels (Belgium) arriving at 12/18/2025 6:45:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 20m
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Lauda Europe8h 25m08:20 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:45 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lauda Europe goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/18/2025 8:20:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/18/2025 4:45:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 8h 25m
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Skyscanner8h 55m012:15 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport9:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/18/2025 12:15:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $298 per person are available. Travel duration is 8h 55m
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Skyscanner10h 30m06:05 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:35 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/18/2025 6:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/18/2025 4:35:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 10h 30m
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Wizz Air16h 30m04:25 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:55 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/18/2025 4:25:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/19/2025 8:55:00 AM. 50 Economy ticket for $246 per person are available. Travel duration is 16h 30m
Fastest Buses Thursday
Fastest Flights Thursday
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FlixBus7h 35m011:10 PMKarlsruheCentral Station6:45 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/19/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/20/2025 6:45:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 7h 35m
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FlixBus10h 20m08:25 AMKarlsruheCentral Station6:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/19/2025 8:25:00 AM to North Station, Brussels (Belgium) arriving at 12/19/2025 6:45:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 10h 20m
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FlixBus10h 35m05:55 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/19/2025 5:55:00 AM to North Station, Brussels (Belgium) arriving at 12/19/2025 4:30:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 35m
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FlixBus10h 35m04:50 PMKarlsruheCentral Station3:25 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/19/2025 4:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/20/2025 3:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 10h 35m
Fastest Buses Friday
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FlixBus7h 30m010:45 AMKarlsruheCentral Station6:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/20/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/20/2025 6:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 30m
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FlixBus7h 35m011:10 PMKarlsruheCentral Station6:45 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/20/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/21/2025 6:45:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 7h 35m
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FlixBus9h 40m03:50 AMKarlsruheCentral Station1:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/20/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/20/2025 1:30:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 9h 40m
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FlixBus9h 40m06:50 AMKarlsruheCentral Station4:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/20/2025 6:50:00 AM to North Station, Brussels (Belgium) arriving at 12/20/2025 4:30:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 9h 40m
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Skyscanner9h 10m011:00 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/20/2025 11:00:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/20/2025 8:10:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 9h 10m
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Skyscanner12h 20m06:00 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport6:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/20/2025 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/20/2025 6:20:00 PM. 50 Economy ticket for $521 per person are available. Travel duration is 12h 20m
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Skyscanner13h 30m06:40 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport8:10 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/20/2025 6:40:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/20/2025 8:10:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 13h 30m
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Skyscanner25h 0m012:05 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport1:05 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 12/20/2025 12:05:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/21/2025 1:05:00 PM. 50 Economy ticket for $295 per person are available. Travel duration is 25h 0m
Fastest Buses Saturday
Fastest Flights Saturday
Here you will find all operators and timetables for a
Bus from Karlsruhe to Brussels
What are the most popular stations in Karlsruhe and Brussels?
In Karlsruhe, you will usually depart from Central Station, Heidehof Train Station or Tullastraße / Verkehrsbetriebe Train Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Karlsruhe? With 9 connections between 3 Bus, Train and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Karlsruhe and Brussels, you can pay as low as $28 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from Deutsche Bahn: you will get to Brussels in just 4h 53m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Karlsruhe and Brussels are FlixBus, Skyscanner and Deutsche Bahn, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Karlsruhe and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Ettlingen or to Saint-Gilles, and look at flights from Karlsruhe/Baden-Baden Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Karlsruhe to Brussels?
The most popular companies between Karlsruhe and Brussels, are FlixBus, Skyscanner and Deutsche Bahn. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Train companies: Deutsche Bahn
Airlines: Skyscanner, Ryanair, Lauda Europe and 2 more.
All you need to know when you travel from Karlsruhe to Brussels
Check all information on comfort and services on all modes of transports from Karlsruhe to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Karlsruhe to Brussels
How can I reach Brussels from Karlsruhe?
Every day, there are on average 9 connections between Bus, Train and Flight, with which you can get to Brussels from Karlsruhe.
How far is Brussels from Karlsruhe?
The distance between Karlsruhe and Brussels is 220.7 miles.
What is the most ecofriendly mode of transport between Karlsruhe and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 10 kgs of CO2, a train 12 kgs, a car 60 kgs, and a flight 87 kgs.
What is the cheapest mode of transport from Karlsruhe to Brussels?
You can get to Brussels with just $28 by taking a Bus from FlixBus.
What is the fastest way to get from Karlsruhe to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 4h 53m with a Train from Deutsche Bahn.
More routes to Karlsruhe and to Brussels
Looking for more options? Here you can see the most popular routes to Karlsruhe and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Karlsruhe
- Barcelona to Karlsruhe
- Berlin to Karlsruhe
- Bremen to Karlsruhe
- Dortmund to Karlsruhe
- Dresden to Karlsruhe
- Dusseldorf to Karlsruhe
- Frankfurt am Main Airport to Karlsruhe
- Frankfurt am Main to Karlsruhe
- Frankfurt Hahn Airport to Karlsruhe
- Freiburg to Karlsruhe
- Hamburg to Karlsruhe
- Heidelberg to Karlsruhe
- Innsbruck to Karlsruhe
- Mannheim to Karlsruhe
- Memmingen Airport to Karlsruhe
- Milan to Karlsruhe
- Munich to Karlsruhe
- Nuremberg to Karlsruhe
- Paris to Karlsruhe
- Saarbruecken to Karlsruhe
- Strasbourg to Karlsruhe
- Stuttgart Airport to Karlsruhe
- Stuttgart to Karlsruhe
- Vienna to Karlsruhe
- Trips to Brussels
- Amsterdam to Brussels
- Angers to Brussels
- Berlin to Brussels
- Bern to Brussels
- Besancon to Brussels
- Bruges (BE) to Brussels
- Brussels South Charleroi Airport to Brussels
- Cologne to Brussels
- Cologne/Bonn Airport to Brussels
- Eindhoven to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Maastricht to Brussels
- Milan to Brussels
- Montpellier to Brussels
- Nottingham to Brussels
- Paris to Brussels
- Porto to Brussels
- Rotterdam to Brussels
- Salzburg to Brussels
- Utrecht to Brussels
- Valence to Brussels
- Zurich to Brussels

