Bus Karlsruhe to Brussels: Compare prices and save money

Compare all timetables for the bus from Karlsruhe to Brussels

Here is a selection of the cheapest bus trips from the schedule from Karlsruhe to Brussels from various bus operators like FlixBus for the next days.

today

$26

tomorrow

$33

Sunday

$28

Monday

Tuesday

$21

Wednesday

$27

Thursday

$30

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 30m	10:45 AM	Karlsruhe	Central Station	6:15 PM	Brussels	North Station	Economy	$26	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/5/2025 6:15:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 7h 30m
FlixBus	7h 35m	11:10 PM	Karlsruhe	Central Station	6:45 AM	Brussels	North Station	Economy	$30	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/6/2025 6:45:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 7h 35m
FlixBus	10h 5m	9:15 PM	Karlsruhe	Central Station	7:20 AM	Brussels	Midi Bus Station	Economy	$32	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 9:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/6/2025 7:20:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 5m
FlixBus	10h 50m	3:50 AM	Karlsruhe	Central Station	2:40 PM	Brussels	North Station	Economy	$33	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/5/2025 2:40:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 10h 50m
FlixBus	10h 35m	5:55 AM	Karlsruhe	Central Station	4:30 PM	Brussels	North Station	Economy	$33	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/5/2025 5:55:00 AM to North Station, Brussels (Belgium) arriving at 12/5/2025 4:30:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 10h 35m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 35m	11:10 PM	Karlsruhe	Central Station	6:45 AM	Brussels	North Station	Economy	$33	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/7/2025 6:45:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 7h 35m
FlixBus	9h 40m	6:50 AM	Karlsruhe	Central Station	4:30 PM	Brussels	North Station	Economy	$35	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 6:50:00 AM to North Station, Brussels (Belgium) arriving at 12/6/2025 4:30:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 9h 40m
FlixBus	10h 20m	8:25 AM	Karlsruhe	Central Station	6:45 PM	Brussels	North Station	Economy	$36	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 8:25:00 AM to North Station, Brussels (Belgium) arriving at 12/6/2025 6:45:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 20m
FlixBus	10h 5m	9:15 PM	Karlsruhe	Central Station	7:20 AM	Brussels	Midi Bus Station	Economy	$36	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 9:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/7/2025 7:20:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 5m
FlixBus	9h 40m	3:50 AM	Karlsruhe	Central Station	1:30 PM	Brussels	North Station	Economy	$39	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/6/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/6/2025 1:30:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 9h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 30m	10:45 AM	Karlsruhe	Central Station	6:15 PM	Brussels	North Station	Economy	$28	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/7/2025 6:15:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 30m
FlixBus	7h 35m	11:10 PM	Karlsruhe	Central Station	6:45 AM	Brussels	North Station	Economy	$31	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/8/2025 6:45:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 7h 35m
FlixBus	10h 45m	4:50 PM	Karlsruhe	Central Station	3:35 AM	Brussels	Midi Bus Station	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 4:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/8/2025 3:35:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 45m
FlixBus	10h 5m	9:15 PM	Karlsruhe	Central Station	7:20 AM	Brussels	Midi Bus Station	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 9:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/8/2025 7:20:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 5m
FlixBus	9h 40m	3:50 AM	Karlsruhe	Central Station	1:30 PM	Brussels	North Station	Economy	$44	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/7/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/7/2025 1:30:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 40m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 30m	10:45 AM	Karlsruhe	Central Station	6:15 PM	Brussels	North Station	Economy	$21	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 10:45:00 AM to North Station, Brussels (Belgium) arriving at 12/9/2025 6:15:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 7h 30m
FlixBus	7h 35m	11:10 PM	Karlsruhe	Central Station	6:45 AM	Brussels	North Station	Economy	$26	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/10/2025 6:45:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 7h 35m
FlixBus	10h 50m	3:50 AM	Karlsruhe	Central Station	2:40 PM	Brussels	North Station	Economy	$29	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/9/2025 2:40:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 10h 50m
FlixBus	10h 45m	4:50 PM	Karlsruhe	Central Station	3:35 AM	Brussels	Midi Bus Station	Economy	$34	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/9/2025 4:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/10/2025 3:35:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 45m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 35m	11:10 PM	Karlsruhe	Central Station	6:45 AM	Brussels	North Station	Economy	$27	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/10/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/11/2025 6:45:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 7h 35m
FlixBus	10h 50m	3:50 AM	Karlsruhe	Central Station	2:40 PM	Brussels	North Station	Economy	$30	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/10/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/10/2025 2:40:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 10h 50m
FlixBus	9h 30m	11:05 AM	Karlsruhe	Central Station	8:35 PM	Brussels	North Station	Economy	$42	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/10/2025 11:05:00 AM to North Station, Brussels (Belgium) arriving at 12/10/2025 8:35:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 9h 30m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 35m	11:10 PM	Karlsruhe	Central Station	6:45 AM	Brussels	North Station	Economy	$30	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 11:10:00 PM to North Station, Brussels (Belgium) arriving at 12/12/2025 6:45:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 7h 35m
FlixBus	10h 20m	8:25 AM	Karlsruhe	Central Station	6:45 PM	Brussels	North Station	Economy	$32	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 8:25:00 AM to North Station, Brussels (Belgium) arriving at 12/11/2025 6:45:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 20m
FlixBus	10h 5m	9:15 PM	Karlsruhe	Central Station	7:20 AM	Brussels	Midi Bus Station	Economy	$32	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 9:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/12/2025 7:20:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 5m
FlixBus	10h 50m	3:50 AM	Karlsruhe	Central Station	2:40 PM	Brussels	North Station	Economy	$33	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/11/2025 2:40:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 10h 50m
FlixBus	10h 15m	6:15 AM	Karlsruhe	Central Station	4:30 PM	Brussels	North Station	Economy	$33	A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/11/2025 6:15:00 AM to North Station, Brussels (Belgium) arriving at 12/11/2025 4:30:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 10h 15m

Best Price Offer: The price for the cheapest bus from Karlsruhe to Brussels is $21 on 12/9/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Karlsruhe and Brussels

See here how frequent the connections between Karlsruhe and Brussels are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Karlsruhe to Brussels. Wednesday has instead the fewest connections, with only 3 daily coaches between Karlsruhe and Brussels.

The busiest time of the day is the Morning, with 11 buses from Karlsruhe to Brussels, while Afternoon sees the fewest connections between Karlsruhe and Brussels, with 3 offers.

Facts about the bus from Karlsruhe to Brussels

Compare all providers like FlixBus that travel 5 times every day by bus from Karlsruhe to Brussels in one click! Book your bus ticket from Karlsruhe to Brussels starting from $21!

Cheapest Bus	$21
Fastest Bus	7h 30m
Earliest Bus	3:50 AM
Latest Bus	11:10 PM
Daily Bus Routes	5 Ø
Distance	220.7 miles
Bus Companies	FlixBus

Cheapest bus connections from Karlsruhe to Brussels

Every day, 5 buses from 1 bus companies leave Karlsruhe for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$26

Saturday 12/06

$33

Sunday 12/07

$28

Monday 12/08

Tuesday 12/09

$21

Wednesday 12/10

$27

Thursday 12/11

$30

Friday 12/12

Saturday 12/13

$25

Sunday 12/14

$27

Monday 12/15

Tuesday 12/16

$29

Wednesday 12/17

Thursday 12/18

$34

Friday 12/19

Saturday 12/20

$40

Sunday 12/21

$43

Monday 12/22

$47

Tuesday 12/23

$56

Wednesday 12/24

$47

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Karlsruhe to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Karlsruhe to Brussels, for the next 30 days.

With a price starting from $21, Tuesday is the cheapest day for a bus from Karlsruhe to Brussels. Thursday instead is the most expensive day with prices starting from $30.

Morning is the cheapest day time for bus tickets from Karlsruhe to Brussels, with $21. Afternoon is the most expensive time of the day with prices starting from $34.

How to save money travelling from Karlsruhe to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Karlsruhe to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Brussels are also emptier.

All bus stations and stops in Karlsruhe and Brussels

In the map below, you can see where to find all bus stations in Karlsruhe and Brussels.

Central Bus Station

Central Station

Hinterm Hauptbahnhof 6

Durlach Train Station

Knielingen Train Station

Durlach Auer Str./Dr.Willmar Schwabe Bus Stop

Midi Bus Station

Avenue Fonsny 1

North Station

Rue du Progrès 80

Congrès

Boulevard Pachéco 7

Central Station

City Tours

Rue du Marché Aux Herbes 82

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Karlsruhe to Brussels? Compare all modes of transports from Karlsruhe to Brussels.

Service and Comfort on the bus from Karlsruhe to Brussels

Want to know which seat classes are available on the buses from Karlsruhe to Brussels? Or which bus companies serve the route Karlsruhe to Brussels? Below you will find answers to your questions.

FAQs about the Karlsruhe to Brussels bus

How much does a Karlsruhe Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $21 and takes 7h 30m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Karlsruhe to Brussels?

This route is offered by 1 companies with a range of ticket prices between $21 and $72. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Karlsruhe to Brussels each day?

Every day, the Karlsruhe to Brussels bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Karlsruhe to Brussels take?

The fastest bus from Karlsruhe to Brussels is offered by FlixBus and takes 7h 30m. Bus tickets for this connection cost $26. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Karlsruhe to Brussels?

The earliest bus arriving in Brussels from Karlsruhe starts at 3:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Karlsruhe to Brussels?

The latest bus trip departing from Karlsruhe for Brussels starts at 11:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Karlsruhe Brussels route?

When traveling by bus from Karlsruhe to Brussels, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Karlsruhe and Brussels?

You can check all the direct connections between Karlsruhe and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Karlsruhe to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Karlsruhe Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Karlsruhe Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Karlsruhe to Brussels on your planned travel date.

Available seat classes which are offered on the bus route Karlsruhe to Brussels

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Karlsruhe and to Brussels

Here’s an overview of the most popular bus routes to Karlsruhe and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!