Bus from Karlsruhe to Brussels from $27

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Karlsruhe to Brussels

Here is a selection of the cheapest bus trips from the schedule from Karlsruhe to Brussels from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today
from $30
tomorrow
from $33
Monday
from $36
Tuesday
from $27
Wednesday
from $37
Thursday
from $33
Friday
from $42

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    7h 30m
    0
    10:45 AM
    Karlsruhe
    Central Station
    6:15 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $30
  • FlixBus
    9h 40m
    0
    6:50 AM
    Karlsruhe
    Central Station
    4:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    10h 5m
    0
    9:15 PM
    Karlsruhe
    Central Station
    7:20 AM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    10h 40m
    0
    3:15 AM
    Karlsruhe
    Central Station
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $39
  • FlixBus
    9h 40m
    0
    3:50 AM
    Karlsruhe
    Central Station
    1:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $40

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    7h 30m
    0
    10:45 AM
    Karlsruhe
    Central Station
    6:15 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $33
  • FlixBus
    9h 40m
    0
    3:50 AM
    Karlsruhe
    Central Station
    1:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $41
  • FlixBus
    9h 40m
    0
    6:50 AM
    Karlsruhe
    Central Station
    4:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $41
  • FlixBus
    10h 40m
    0
    3:15 AM
    Karlsruhe
    Central Station
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $41
  • FlixBus
    7h 35m
    0
    11:10 PM
    Karlsruhe
    Central Station
    6:45 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $43

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    10h 40m
    0
    3:15 AM
    Karlsruhe
    Central Station
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    10h 5m
    0
    9:15 PM
    Karlsruhe
    Central Station
    7:20 AM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    10h 30m
    0
    3:50 AM
    Karlsruhe
    Central Station
    2:20 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $36
  • BlaBlaCar Bus
    8h 5m
    0
    12:25 AM
    Karlsruhe
    Central Station
    8:30 AM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $43
  • BlaBlaCar Bus
    7h 45m
    0
    9:05 PM
    Karlsruhe
    Central Station
    4:50 AM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $44

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    10h 30m
    0
    3:50 AM
    Karlsruhe
    Central Station
    2:20 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $27
  • FlixBus
    10h 35m
    0
    5:55 AM
    Karlsruhe
    Central Station
    4:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $28
  • FlixBus
    7h 30m
    0
    10:45 AM
    Karlsruhe
    Central Station
    6:15 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $29
  • FlixBus
    10h 40m
    0
    3:15 AM
    Karlsruhe
    Central Station
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $31
  • FlixBus
    7h 35m
    0
    11:10 PM
    Karlsruhe
    Central Station
    6:45 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $33

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    7h 35m
    0
    11:10 PM
    Karlsruhe
    Central Station
    6:45 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    10h 40m
    0
    3:15 AM
    Karlsruhe
    Central Station
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $39
  • FlixBus
    10h 30m
    0
    3:50 AM
    Karlsruhe
    Central Station
    2:20 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $40
  • FlixBus
    10h 35m
    0
    5:55 AM
    Karlsruhe
    Central Station
    4:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $40
  • FlixBus
    9h 30m
    0
    11:05 AM
    Karlsruhe
    Central Station
    8:35 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $40

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    7h 35m
    0
    11:10 PM
    Karlsruhe
    Central Station
    6:45 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $33
  • FlixBus
    10h 20m
    0
    8:25 AM
    Karlsruhe
    Central Station
    6:45 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $34
  • FlixBus
    10h 5m
    0
    9:15 PM
    Karlsruhe
    Central Station
    7:20 AM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $36
  • FlixBus
    10h 30m
    0
    3:50 AM
    Karlsruhe
    Central Station
    2:20 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    10h 40m
    0
    3:15 AM
    Karlsruhe
    Central Station
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $38

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    7h 30m
    0
    10:45 AM
    Karlsruhe
    Central Station
    6:15 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $42
  • FlixBus
    7h 35m
    0
    11:10 PM
    Karlsruhe
    Central Station
    6:45 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $47
  • FlixBus
    10h 30m
    0
    3:50 AM
    Karlsruhe
    Central Station
    2:20 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $50
  • FlixBus
    10h 40m
    0
    3:15 AM
    Karlsruhe
    Central Station
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $50
  • FlixBus
    10h 5m
    0
    9:15 PM
    Karlsruhe
    Central Station
    7:20 AM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $50

Frequency of bus connections between Karlsruhe and Brussels

See here how frequent the connections between Karlsruhe and Brussels are, during different times and days of the week.
Monday is the busiest day, with more than 11 daily buses from Karlsruhe to Brussels. Tuesday has instead the fewest connections, with only 6 daily coaches between Karlsruhe and Brussels.
The busiest time of the day is the Night, with 20 buses from Karlsruhe to Brussels, while Afternoon sees the fewest connections between Karlsruhe and Brussels, with 7 offers.

Facts about the bus from Karlsruhe to Brussels

Compare all providers like FlixBus and BlaBlaCar Bus that travel 7 times every day by bus from Karlsruhe to Brussels in one click! Book your bus ticket from Karlsruhe to Brussels starting from $27!

Cheapest Bus $27
Fastest Bus 7h 30m
Earliest Bus 1:40 AM
Latest Bus 11:10 PM
Daily Bus Routes 7 Ø
Distance 220.7 miles
Bus Companies FlixBus and BlaBlaCar Bus

Cheapest bus connections from Karlsruhe to Brussels

Every day, 7 buses from 2 bus companies leave Karlsruhe for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/12/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12
$30
Sunday 07/13
$33
Monday 07/14
$36
Tuesday 07/15
$27
Wednesday 07/16
$37
Thursday 07/17
$33
Friday 07/18
$42
Saturday 07/19
$36
Sunday 07/20
Monday 07/21
$37
Tuesday 07/22
$30
Wednesday 07/23
$34
Thursday 07/24
$36
Friday 07/25
$41
Saturday 07/26
Sunday 07/27
$40
Monday 07/28
Tuesday 07/29
Wednesday 07/30
Thursday 07/31
Friday 08/01
Saturday 08/02

The cheapest time to travel from Karlsruhe to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Karlsruhe to Brussels, for the next 30 days.
With a price starting from $27, Tuesday is the cheapest day for a bus from Karlsruhe to Brussels. Friday instead is the most expensive day with prices starting from $42.
Night is the cheapest day time for bus tickets from Karlsruhe to Brussels, with $27. Afternoon is the most expensive time of the day with prices starting from $36.

How to save money travelling from Karlsruhe to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Karlsruhe to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Brussels are also emptier.

All bus stations and stops in Karlsruhe and Brussels

In the map below, you can see where to find all bus stations in Karlsruhe and Brussels.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Karlsruhe to Brussels? Compare all modes of transports from Karlsruhe to Brussels.

Service and Comfort on the bus from Karlsruhe to Brussels

Want to know which seat classes are available on the buses from Karlsruhe to Brussels? Or which bus companies serve the route Karlsruhe to Brussels? Below you will find answers to your questions.

FAQs about the Karlsruhe to Brussels bus

How much does a Karlsruhe Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $27 and takes 10h 30m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Karlsruhe to Brussels?

This route is offered by 2 companies with a range of ticket prices between $27 and $66. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Karlsruhe to Brussels each day?

Every day, the Karlsruhe to Brussels bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Karlsruhe to Brussels take?

The fastest bus from Karlsruhe to Brussels is offered by FlixBus and takes 7h 30m. Bus tickets for this connection cost $30. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Karlsruhe to Brussels?

The earliest bus arriving in Brussels from Karlsruhe starts at 1:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Karlsruhe to Brussels?

The latest bus trip departing from Karlsruhe for Brussels starts at 11:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Karlsruhe Brussels route?

When traveling by bus from Karlsruhe to Brussels, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Karlsruhe and Brussels?

You can check all the direct connections between Karlsruhe and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Karlsruhe to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Karlsruhe Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Karlsruhe Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Karlsruhe to Brussels on your planned travel date.

Available seat classes which are offered on the bus route Karlsruhe to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Karlsruhe and to Brussels

Here’s an overview of the most popular bus routes to Karlsruhe and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.